Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

PKHD1, fibrocystin/polyductin

 E1BK86_BOVIN            Unreviewed;      4071 AA.
E1BK86;
02-NOV-2010, integrated into UniProtKB/TrEMBL.
16-NOV-2011, sequence version 2.
28-MAR-2018, entry version 52.
SubName: Full=PKHD1, fibrocystin/polyductin {ECO:0000313|Ensembl:ENSBTAP00000032158};
Name=PKHD1 {ECO:0000313|Ensembl:ENSBTAP00000032158,
ECO:0000313|VGNC:VGNC:32939};
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000032158, ECO:0000313|Proteomes:UP000009136};
[1] {ECO:0000313|Ensembl:ENSBTAP00000032158, ECO:0000313|Proteomes:UP000009136}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000032158,
ECO:0000313|Proteomes:UP000009136};
PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42;
Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C.,
Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S.,
Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.;
"A whole-genome assembly of the domestic cow, Bos taurus.";
Genome Biol. 10:R42.01-R42.10(2009).
[2] {ECO:0000313|Ensembl:ENSBTAP00000032158}
IDENTIFICATION.
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000032158};
Ensembl;
Submitted (MAR-2016) to UniProtKB.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; DAAA02055245; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055246; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055247; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055249; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055250; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055251; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055252; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02055254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9913.ENSBTAP00000032158; -.
PaxDb; E1BK86; -.
Ensembl; ENSBTAT00000032221; ENSBTAP00000032158; ENSBTAG00000011237.
VGNC; VGNC:32939; PKHD1.
eggNOG; ENOG410IEIF; Eukaryota.
eggNOG; ENOG410XQ01; LUCA.
GeneTree; ENSGT00780000121902; -.
InParanoid; E1BK86; -.
OMA; WVAGIKV; -.
OrthoDB; EOG091G00JT; -.
TreeFam; TF329582; -.
Proteomes; UP000009136; Chromosome 23.
Bgee; ENSBTAG00000011237; -.
GO; GO:0016324; C:apical plasma membrane; IEA:Ensembl.
GO; GO:0005813; C:centrosome; IEA:Ensembl.
GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0072686; C:mitotic spindle; IEA:Ensembl.
GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
GO; GO:0001822; P:kidney development; IEA:Ensembl.
GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
GO; GO:0051898; P:negative regulation of protein kinase B signaling; IEA:Ensembl.
GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
GO; GO:0010824; P:regulation of centrosome duplication; IEA:Ensembl.
GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
GO; GO:0032006; P:regulation of TOR signaling; IEA:Ensembl.
Gene3D; 2.160.20.10; -; 2.
Gene3D; 2.60.40.10; -; 5.
InterPro; IPR019316; G8_domain.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR014756; Ig_E-set.
InterPro; IPR002909; IPT_dom.
InterPro; IPR037524; PA14/GLEYA.
InterPro; IPR011658; PA14_dom.
InterPro; IPR006626; PbH1.
InterPro; IPR012334; Pectin_lyas_fold.
InterPro; IPR011050; Pectin_lyase_fold/virulence.
InterPro; IPR028839; PKHD1.
PANTHER; PTHR45107; PTHR45107; 1.
Pfam; PF10162; G8; 2.
Pfam; PF07691; PA14; 1.
Pfam; PF01833; TIG; 7.
SMART; SM01225; G8; 2.
SMART; SM00429; IPT; 5.
SMART; SM00710; PbH1; 11.
SUPFAM; SSF51126; SSF51126; 3.
SUPFAM; SSF81296; SSF81296; 6.
PROSITE; PS51484; G8; 2.
PROSITE; PS51820; PA14; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000009136};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000009136};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 17 {ECO:0000256|SAM:SignalP}.
CHAIN 18 4071 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5003144126.
TRANSMEM 3850 3873 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 323 483 PA14. {ECO:0000259|PROSITE:PS51820}.
DOMAIN 1926 2047 G8. {ECO:0000259|PROSITE:PS51484}.
DOMAIN 2741 2867 G8. {ECO:0000259|PROSITE:PS51484}.
SEQUENCE 4071 AA; 444214 MW; 728CB4DDEDF764BD CRC64;
MTGWLISLTS IKVLLLAVPC LNIHIEPEEG SLAGGTWITV IFDGLELGLL HPANGSQLEI
HLVNVALPTL PSIPCDVSPV FLDVPAVMCR TRSLLPEAQE GVYSLEVQAG GQVVGSPHPG
PQDGRTFKFS RAQTPIVYKV NPPSGVPGKL IHVYGWIITG RSETFDFDAE YIDSPLILEA
QGDKWITPCS LVNRQTGSHY PIQEDHGLGT LQCRVEGNYI GSQNVSFSVF NKGKSVIHKD
AWLVSAKQDL FLYQTYSEIL SVFPETGSLG GRTDITIIGD FFDNPAQVTI AGIPCDIRHV
SPRRIECTTR APSKGARLSA PQAGNRGLLF EVGDASEDLD LTEATPGYSW QIVPNASSPS
GFWSKEGQPF RARLSGFFVA PETNNYTFWI QADNQASLYF SWSEDLRTKV KMASIRVGTA
DWFDSWEQNG SDKTQQQKTP KLELLGGARY YLEAEHRGRA PSSGVRIGVQ IHNTWLNPDV
VSTYLREKHQ IRAWAQRLPE IQMLTLSGTG NFFLTWDNVS SQPIPANATA HQIQTAIEEL
LAVKCKLEPL SANILLWLGF EQGLEGSTSD GHLTSGTEPF CGRFSLHQPR HLVLTPPAVQ
KVYRLDQYTH LCLAYRGHEN TTLKMTVSFT IGLQNPVKNI TCDWSLLGTS PKCWQFTCTD
LWKMCVHHAS HLQLPPANSP VLVHQIDLLP LSPEMGMFYV DEIIIADTNL TVSQADTGTA
RPGGNLLELL SVVGSPPVYS VTSWLAGCGL ELPLITASAV PTEGAEEGSR LVQVTTQRLQ
RTSPPLGGHF RIQLSNTAIP GVPVHISASH LQKLLQTSAD DFTSRYLNAS DFTVTEDLKS
CYEHVWTFSW SSRVGDLPNF IKVSNENLTG VNPAVTTRVV YDGGVFLGPI FGDMLVTANQ
HTQVVVRVND IPAYCSGSCA FQYLEGSTPQ VYSVWYALAY DMDLLVYITG TSFSGDYKAL
QVTVNKTSCN VIFSNQTNVV CQTSLLPIGL HQISMLVRPS GLAINASGGG LFLNVEPRLD
TVEPSRAADI GGLWATIRGS GLDNVNLVLF GSQSCVINVT TSNSRRIQCK VPSKGEDGPT
VNVTVILGGH PVVLAMAFTY VSSLNPVIVS LSRNGSSIAG GEILSIGMLL PVNHTDLDAE
VRIGDTRAWV LAQTAQGLEV VLPPLPAGLH GISVSINGVH IHAQGVDLHI QYITQVFSIQ
PCCGSLVGGT ILSISGRGFS RDRALLWVLV GNRSCDIVNS TETSIWCETP PPAPLPLSAP
VPVEVWAGSK PFPHRPSPRL VGKGFTFMYE VAATPVVTAM RGEVTNHSLR LYVEGQNLFD
SVVLLGNLSC DLQTPSPGSN LSPAGCTFPL DTLEAGLYPL QVHQRQMGFA DMSAVPQQCV
VMPQITSIFP TRGSTCGGTV LTVRGLALRS SRGSVEVDLS GPFTCVILSL GDQTVLCRIT
PVGDPLPGTS FALNVTILVN GLPSMCQGNC TLFLCEETTP IVDDWTTNIS GSLTTVLVRG
QRLGITADEP VVFVDDRLAC TVAFHNASHV ACWISDLSPG PHYLSVFHAR YGYACSGNLS
RHFHVWPQVF HYFPKNFSLH GGSLLTLEGT ALKGLNSTLV YIGQQACLTV SLGSELIQCA
VPAGNGSAAL VIEVDGLSYQ MGVIGYSSAF TPELLSVSQT EDVLTFSVAR ISGAANVDIF
IGMSPCVGVS GNHTLLHCLV PSLPTGEYQV RGYDRMRGWA SSILMFTSRV TITAVTENFG
RLGGRLVHVF GAGFSPGNIS AAVCGTPCQV LANATVSAFS CLVLPLDVSL ASLCDLRPEE
EDCETASCSY VHCDLIITVG TESLPESWPY FYICEESSRC LLARDHWTES ILPSFSGLFI
SPKVERDEVL IYNSSCTITM ETEAKMECET PNQPITAKIT EIRKSRGQNT QGNFIFQFCG
RWSRAHSWFP QRPPQEGDNV TVEKGQLLLL DTNTSILNFL HVKGGKLIFL DLGPIELRTH
SILVSDGGEL RIGSEDKPFQ GKARIKLYGS SYSARFFPYG VKFLAVRNGT LSLHGSLPEV
VVTHLRAAAN AHDTVLALED AVDWHAGDEV LVISGMGAED AKPKEEIVTV ETVHSTDLQL
RSPLRYSHNS TEKWVAGEHH VLKVMLVLLS RSITIQGNLT DERVQFLASC QGASASEGDL
QNCLYSKSEK MLGSRDLGAR VIVQSFPEEP SRVQLKGVQF RDLGQAFHEH VSSLMLVGAM
RGSYVQGCTV RRSFSRGLSM SQTSGLKVDS NVFYDISGHA LLLGTSPEIR YILWEVTSGG
GKDWSEQGNI IRNNVIIRVS GAEGLSSPEV VTPSGIYIRH PTNVIEGNRV FAAGYGYFFH
LVTNQTSQAP LLSFTRNSAH SCTRSGLFVY PKFQPPWDNS AGSTLFQNFT VWGSAGGAQI
FRSSNLHLKN FQVYACRDFG IDVLESDANT SITDSLLLGH FAHKGNLCMS AGIKSPRRWE
LRVSNTTFVN FDLTHCVAIR TCSGCSQGQG GFTVKTNQLK FMNSPNLVAF PSPHAAILED
LDGSLSGKNR SHILASMETL PATCVVKASF SQLVHGSVCE ENVLFHRMSI GLASALKVSQ
DLTITDSRNK TTTVSYVHDT LSNPYGWMAL LLDQETYSLR FESPWTSSAL QYSATFDNFA
PGNFLLLVHT DVWVYPDILI KCGSHVGRSL SSLPSPGQDQ GCDWFFDSQL RQLTYLVSGE
GQVKVVLQVR KGVDPTISAS ISVPESVLKW SLPEAWEGVA EGWGGHSGAS PGPGEDVLIL
SNRTVLVDTD LPPLRGLYVM GTLEFPVDRS NVLSVACMLI AGGELRVGTS ENPLEKEKKL
LILLRASEGV FCDRFSGIHI DPGTIGVFGK VQLHSAYPKK SWTRLGADIA SGNERIIVED
AVDWRPHDKI VLSSSSYEPH EAEVLTVKEV RGHHIRIHER LRHRHIGSAH VMEGGRHIRL
AAEVGLLTRN IQIQGDTSCR GGLLVGSFRK SSVEEFSGIL QLYNVEIQNF GSPLYSSIEL
TDVSTGSWVI SSSLHQSCGG GIHAAASQGI ILNDNVVFST AGHGIDLEGQ DYSLSKNLVV
LMTQSAWSPV WVAGIKVNEA KNTRLHGNVV AGSERLGFHI QGHRCSAPES LWSDNVAHSS
LHGLHLYKGS GLDSCTGISG FLAFKNFDYG AMLQVENSME IENLTLVDNT VGLFTAVYVS
SAPRYYIRSL QIVLKNSVIV ATSSSFDCIQ DRVKPHSAHL TSPDRAPSNP RGGRVGILWP
VFTSEPNRWP QEPWHKVRNS HLISGIMKLQ DVTFSSFVKS CYSDDLDVCI LPNAENTGIV
PPIMAERTSM LKIKDKNKFH FPPLQTRKDL ETLVCSESDC ESPGKYLFKD LDGRALGLPP
PVSVFPKTEG EWTGSFFNTG TFREEQKCTY RPLINGYICK QTDPVILILD SADTTWAMQK
LYPVVSVTSG FVDTFSSINA SAPCSISRSV SAFYSIVPTR RITKVCFVDQ TPDVLHFFLL
GNKNTSKLLL AVFYHELQSP YVFSGDRFIP PTQVHSTSSL LNESIGSNYF SITDNLLYVV
LQGEKPIEIR SSVSIHLALN VMFSVLEKGW EIVILERLTV FLQINQDQIR FIHQMPGNEA
TLKAMADSRA KRKRNCPTVT CTSHDRVGQR RPLMVEMSSY RDLPTMEMIS KVMVIEIGDL
PTVRNAGLIP SLSSNKLQNL AHQVIIAQQT GLLESVLNMT IGALLVTQSK GIIGYGNTSS
FKTGNLIYVR PYGLSVFVQP SDGEVGKELT VQPQLVFLDK QNRRVESLGP PSEPWVISVS
LEGTLDSVLR GCTHAETQDG YVSFSNLAVL ISGSNWHFIF TVTSPPGVNF TARSRSFAVL
PVTPSERSTI IMAASLCSGV SWLALCCLVC CWFKKSKTRK IKNEEISETQ TSDQRNHSHV
SPKHQGSRVE TEKEVTMMAE DLRMKVMLAK LNQLPHQSLN GVSRRKVSHR VVREEGGSRE
EAAVPAPSIT SVTSPRNTCT PGSPAQQVYL QESGGWKGAQ EQVLRYQLAG QDQLLLLCPD
LRRERQRLQG QSQLGKGHIS LGLSQKKPGS CGATEAFCLH SVHPEAVQEQ L


Related products :

Catalog number Product name Quantity
EIAAB31281 FCYT,Fibrocystin,Homo sapiens,Human,PKHD1,Polycystic kidney and hepatic disease 1 protein,Polyductin,TIGM1,Tigmin
EIAAB31312 Fibrocystin-L,Homo sapiens,Human,PKHD1L1,PKHD1-like protein 1,Polycystic kidney and hepatic disease 1-like protein 1
EIAAB31311 Fibrocystin-L,Mouse,Mus musculus,Pkhd1l1,PKHD1-like protein 1,Polycystic kidney and hepatic disease 1-like protein 1,Protein D86
CSB-EL018067MO Mouse Fibrocystin-L(PKHD1L1) ELISA kit 96T
CSB-EL018067HU Human Fibrocystin-L(PKHD1L1) ELISA kit 96T
CSB-EL018067MO Mouse Fibrocystin-L(PKHD1L1) ELISA kit SpeciesMouse 96T
PKHL1_MOUSE ELISA Kit FOR Fibrocystin-L; organism: Mouse; gene name: Pkhd1l1 96T
031532A Pkhd1 250ul
017943A PKHD1 250ul
i000197 PKHD1-set siRNA_Lentivectors 500ng (each)
BC110-60477 PKHD1 0.1 ml
BC110-60477 PKHD1 0.1 ml
BC110-60478 PKHD1 0.1 ml
BC110-60480 PKHD1 0.1 ml
BC110-60479 PKHD1 0.1 ml
BC110-60478 PKHD1 0.1 ml
BC110-60480 PKHD1 0.1 ml
BC110-60477 PKHD1 0.1 ml
BC110-60480 PKHD1 0.1 ml
BC110-60479 PKHD1 0.1 ml
BC110-60478 PKHD1 0.1 ml
BC110-60479 PKHD1 0.1 ml
i000197d PKHD1-11817 siRNA_Lentivectors 500ng
i000197c PKHD1-4566 siRNA_Lentivectors 500ng
i000197b PKHD1-3238 siRNA_Lentivectors 500ng


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur