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Paired box 2

 A0A0G2JZ47_RAT          Unreviewed;       153 AA.
A0A0G2JZ47;
22-JUL-2015, integrated into UniProtKB/TrEMBL.
22-JUL-2015, sequence version 1.
23-MAY-2018, entry version 21.
SubName: Full=Paired box 2 {ECO:0000313|Ensembl:ENSRNOP00000070907};
Name=Pax2 {ECO:0000313|Ensembl:ENSRNOP00000070907,
ECO:0000313|RGD:1305568};
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000070907, ECO:0000313|Proteomes:UP000002494};
[1] {ECO:0000313|Ensembl:ENSRNOP00000070907, ECO:0000313|Proteomes:UP000002494}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000070907,
ECO:0000313|Proteomes:UP000002494};
PubMed=15057822; DOI=10.1038/nature02426;
Rat Genome Sequencing Project Consortium;
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T.,
Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A.,
Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M.,
Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K.,
Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S.,
Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J.,
Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y.,
Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A.,
Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J.,
D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R.,
Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A.,
Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E.,
Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E.,
Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D.,
Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M.,
Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O.,
Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O.,
Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H.,
Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S.,
Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J.,
Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E.,
Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F.,
Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K.,
Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S.,
Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M.,
Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M.,
Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A.,
Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S.,
Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G.,
Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H.,
Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R.,
Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M.,
Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H.,
Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S.,
Collins F.S.;
"Genome sequence of the Brown Norway rat yields insights into
mammalian evolution.";
Nature 428:493-521(2004).
[2] {ECO:0000313|Ensembl:ENSRNOP00000070907}
IDENTIFICATION.
STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000070907};
Ensembl;
Submitted (JUN-2015) to UniProtKB.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00381, ECO:0000256|SAAS:SAAS00117811}.
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EMBL; AC128836; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Ensembl; ENSRNOT00000085811; ENSRNOP00000070907; ENSRNOG00000014253.
RGD; 1305568; Pax2.
GeneTree; ENSGT00680000099553; -.
Proteomes; UP000002494; Chromosome 1.
Bgee; ENSRNOG00000014253; -.
ExpressionAtlas; A0A0G2JZ47; baseline and differential.
GO; GO:0005764; C:lysosome; IDA:RGD.
GO; GO:0005634; C:nucleus; IDA:RGD.
GO; GO:0003700; F:DNA binding transcription factor activity; IC:RGD.
GO; GO:0043565; F:sequence-specific DNA binding; IC:RGD.
GO; GO:0007568; P:aging; IEP:RGD.
GO; GO:0048513; P:animal organ development; IMP:RGD.
GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IEP:RGD.
GO; GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.
GO; GO:0031667; P:response to nutrient levels; IEP:RGD.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
CDD; cd00131; PAX; 1.
Gene3D; 1.10.10.10; -; 2.
InterPro; IPR009057; Homeobox-like_sf.
InterPro; IPR001523; Paired_dom.
InterPro; IPR036388; WH-like_DNA-bd_sf.
Pfam; PF00292; PAX; 1.
PRINTS; PR00027; PAIREDBOX.
SMART; SM00351; PAX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS00034; PAIRED_1; 1.
PROSITE; PS51057; PAIRED_2; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002494};
Developmental protein {ECO:0000256|SAAS:SAAS00117810};
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00381,
ECO:0000256|SAAS:SAAS00117818};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00381,
ECO:0000256|SAAS:SAAS00117821};
Paired box {ECO:0000256|PROSITE-ProRule:PRU00381,
ECO:0000256|SAAS:SAAS00117809};
Reference proteome {ECO:0000313|Proteomes:UP000002494};
Signal {ECO:0000256|SAM:SignalP};
Transcription {ECO:0000256|PROSITE-ProRule:PRU00381,
ECO:0000256|SAAS:SAAS00117816};
Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00381,
ECO:0000256|SAAS:SAAS00117816}.
SIGNAL 1 22 {ECO:0000256|SAM:SignalP}.
CHAIN 23 153 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5002546965.
DOMAIN 20 146 Paired. {ECO:0000259|PROSITE:PS51057}.
SEQUENCE 153 AA; 16574 MW; 941E9DB5241375D1 CRC64;
MAGPCCVWGV VFFSCLSPAG HGGVNQLGGV FVNGRPLPDV VRQRIVELAH QGVRPCDISR
QLRVSHGCVS KILGRYYETG SIKPGVIGGS KPKVATPKVV DKIAEYKRQN PTMFAWEIRD
RLLAEGICDN DTVPSVSSIN SSQHGLPSCF QRL


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