Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Peptidoglycan endopeptidase RipA (EC 3.4.-.-) (Resuscitation-promoting factor interaction partner A) (Rpf-interacting protein A)

 RIPA_MYCS2              Reviewed;         497 AA.
A0QX22;
06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
09-JAN-2007, sequence version 1.
27-SEP-2017, entry version 67.
RecName: Full=Peptidoglycan endopeptidase RipA;
EC=3.4.-.-;
AltName: Full=Resuscitation-promoting factor interaction partner A;
Short=Rpf-interacting protein A;
Flags: Precursor;
Name=ripA; OrderedLocusNames=MSMEG_3145, MSMEI_3064;
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155).
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium.
NCBI_TaxID=246196;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700084 / mc(2)155;
Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
Fraser C.M.;
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700084 / mc(2)155;
PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
"Interrupted coding sequences in Mycobacterium smegmatis: authentic
mutations or sequencing errors?";
Genome Biol. 8:R20.1-R20.9(2007).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700084 / mc(2)155;
PubMed=18955433; DOI=10.1101/gr.081901.108;
Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
"Ortho-proteogenomics: multiple proteomes investigation through
orthology and a new MS-based protocol.";
Genome Res. 19:128-135(2009).
[4]
FUNCTION IN CELL DIVISION, AND DISRUPTION PHENOTYPE.
STRAIN=ATCC 700084 / mc(2)155;
PubMed=18463693; DOI=10.1371/journal.ppat.1000001;
Hett E.C., Chao M.C., Deng L.L., Rubin E.J.;
"A mycobacterial enzyme essential for cell division synergizes with
resuscitation-promoting factor.";
PLoS Pathog. 4:E1000001-E1000001(2008).
[5]
INDUCTION.
STRAIN=ATCC 700084 / mc(2)155;
PubMed=22610443; DOI=10.1074/jbc.M112.346544;
Plocinska R., Purushotham G., Sarva K., Vadrevu I.S., Pandeeti E.V.,
Arora N., Plocinski P., Madiraju M.V., Rajagopalan M.;
"Septal localization of the Mycobacterium tuberculosis MtrB sensor
kinase promotes MtrA regulon expression.";
J. Biol. Chem. 287:23887-23899(2012).
-!- FUNCTION: Peptidoglycan endopeptidase that cleaves the bond
between D-glutamate and meso-diaminopimelate. Binds and degrades
high-molecular weight peptidoglycan. Required for normal
separation of daughter cells after cell division and for cell wall
integrity (By similarity). {ECO:0000250,
ECO:0000269|PubMed:18463693}.
-!- SUBUNIT: Monomer. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Secreted. Note=Localizes to the septa.
{ECO:0000250}.
-!- INDUCTION: Expression depends on the two-component regulatory
system MtrA/MtrB. {ECO:0000269|PubMed:22610443}.
-!- DISRUPTION PHENOTYPE: Essential, it cannot be disrupted. Depletion
experiments show cells grow as long, branched chains that form
clumps. Periodic septa and DNA segregation appear to occur
normally along the filaments. Has increased susceptibility to
carbenicillin, a cell wall-targeted antibiotic. Depletion effects
are reversible. {ECO:0000269|PubMed:18463693}.
-!- SIMILARITY: Belongs to the peptidase C40 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; CP000480; ABK70310.1; -; Genomic_DNA.
EMBL; CP001663; AFP39528.1; -; Genomic_DNA.
RefSeq; WP_011728845.1; NZ_CP009494.1.
RefSeq; YP_887460.1; NC_008596.1.
ProteinModelPortal; A0QX22; -.
SMR; A0QX22; -.
STRING; 246196.MSMEG_3145; -.
EnsemblBacteria; ABK70310; ABK70310; MSMEG_3145.
EnsemblBacteria; AFP39528; AFP39528; MSMEI_3064.
GeneID; 4535215; -.
KEGG; msb:LJ00_15640; -.
KEGG; msg:MSMEI_3064; -.
KEGG; msm:MSMEG_3145; -.
PATRIC; fig|246196.19.peg.3106; -.
eggNOG; ENOG4105ZXU; Bacteria.
eggNOG; COG0791; LUCA.
HOGENOM; HOG000045777; -.
KO; K21473; -.
OMA; WGSASIS; -.
OrthoDB; POG091H02HM; -.
Proteomes; UP000000757; Chromosome.
Proteomes; UP000006158; Chromosome.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
InterPro; IPR000064; NLP_P60_dom.
Pfam; PF00877; NLPC_P60; 1.
1: Evidence at protein level;
Cell wall biogenesis/degradation; Complete proteome; Hydrolase;
Protease; Reference proteome; Secreted; Signal.
SIGNAL 1 39 {ECO:0000255}.
CHAIN 40 497 Peptidoglycan endopeptidase RipA.
/FTId=PRO_0000421120.
COMPBIAS 28 280 Ala-rich.
SEQUENCE 497 AA; 51317 MW; 2556CF24316C2381 CRC64;
MRRTVRALAT RVHGRVCAVP LVVGMLLATA LYGGGPAAAD PAAPDNLATL VAKVASADQK
LQELGAAIQT QQETVNKAIV DVQAARDAAA AAQRELEAGQ RGVADANAAI EAAQKRFDSF
AAATYMNGPS RSYLTATDPA DIVNTTATGQ ALIASSQQVM AKLQRARTEQ VNRESAARLA
KEKADQAARD AESSQDNAVA ALKQAQQTFN AQQGELERLA AERAAAQAEL DSVRKVSATG
NAAPAAAPAA APAPAAAPAP VPNSAPAPVP GAQPNPQAAA GNWDRAPSGP ASSGQNWAVW
DPTLPAIPSA FVSGDPIAII NAVLGIASTS AQVTADMGRS FLQKLGILPT PTGFTNGAIP
RVYGREAVEY VIRRGMSQIG VPYSWGGGNA AGPSRGIDSG AGTVGFDCSG LMLYMFAGVG
IKLDHYSGSQ YNAGRKIPSS QMRRGDMIFY GPNASQHVAM YLGNGQMLEA PYTGSHVKVS
PVRTSGMTPY VTRLIEY


Related products :

Catalog number Product name Quantity
EIAAB27227 mNIPA,Mouse,Mus musculus,Nipa,Nuclear-interacting partner of ALK,Nuclear-interacting partner of anaplastic lymphoma kinase,Zc3hc1,Zinc finger C3HC-type protein 1
EIAAB27226 hNIPA,Homo sapiens,HSPC216,Human,NIPA,Nuclear-interacting partner of ALK,Nuclear-interacting partner of anaplastic lymphoma kinase,ZC3HC1,Zinc finger C3HC-type protein 1
10-288-22336F Arfaptin-2 - ADP-ribosylation factor-interacting protein 2; Partner of RAC1; Protein POR1 0.1 mg
10-288-22336F Arfaptin-2 - ADP-ribosylation factor-interacting protein 2; Partner of RAC1; Protein POR1 0.05 mg
15-288-22336B Arfaptin-2 - ADP-ribosylation factor-interacting protein 2; Partner of RAC1; Protein POR1 Polyclonal 0.1 mg
15-288-22336B Arfaptin-2 - ADP-ribosylation factor-interacting protein 2; Partner of RAC1; Protein POR1 Polyclonal 0.05 mg
15-288-22336A Arfaptin-2 - ADP-ribosylation factor-interacting protein 2; Partner of RAC1; Protein POR1 Polyclonal 0.1 mg
15-288-22336A Arfaptin-2 - ADP-ribosylation factor-interacting protein 2; Partner of RAC1; Protein POR1 Polyclonal 0.05 mg
EIAAB28928 E3-14.7K-interacting protein,FIP2,FIP-2,GLC1E,HIP7,HIP-7,Homo sapiens,Human,Huntingtin yeast partner L,Huntingtin-interacting protein 7,Huntingtin-interacting protein L,HYPL,NEMO-related protein,NRP,O
EIAAB46979 DHHC-17,HIP14,HIP-14,HIP3,HIP-3,Homo sapiens,HSPC294,Human,Huntingtin yeast partner H,Huntingtin-interacting protein 14,Huntingtin-interacting protein 3,Huntingtin-interacting protein H,HYPH,KIAA0946,
EIAAB10371 AF9Q34,AIP1,ASK-interacting protein 1,DAB2 interaction protein,DAB2-interacting protein,DAB2IP,Disabled homolog 2-interacting protein,Homo sapiens,Human,KIAA1743
15-288-22308F GIPC PDZ domain-containing protein 1 - RGS19-interacting protein 1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; Tax interaction protein 2; TIP-2 Polyclonal 0.1 mg
18-003-44197 PDZ domain-containing protein GIPC1 - RGS19-interacting protein 1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; Tax interaction protein 2; TIP-2 Polyclonal 0.05 mg Aff Pur
15-288-22308F GIPC PDZ domain-containing protein 1 - RGS19-interacting protein 1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; Tax interaction protein 2; TIP-2 Polyclonal 0.05 mg
10-288-22308F GIPC PDZ domain-containing protein 1 - RGS19-interacting protein 1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; Tax interaction protein 2; TIP-2 0.1 mg
10-288-22308F GIPC PDZ domain-containing protein 1 - RGS19-interacting protein 1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; Tax interaction protein 2; TIP-2 0.05 mg
EIAAB32202 Huntingtin yeast partner C,Huntingtin-interacting protein C,Hypc,Mouse,Mus musculus,Pre-mRNA-processing factor 40 homolog B,Prpf40b
EIAAB32201 Homo sapiens,Human,Huntingtin yeast partner C,Huntingtin-interacting protein C,HYPC,Pre-mRNA-processing factor 40 homolog B,PRPF40B
EIAAB27017 45 kDa NF-AT-interacting protein,45 kDa NFAT-interacting protein,Homo sapiens,Human,NFATC2-interacting protein,NFATC2IP,NIP45,Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein
EIAAB27018 45 kDa NF-AT-interacting protein,45 kDa NFAT-interacting protein,Mouse,Mus musculus,NFATC2-interacting protein,Nfatc2ip,Nip45,Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein
EIAAB37961 HIF1,HIF-1,HIP-1,Histone-lysine N-methyltransferase SETD2,Homo sapiens,hSET2,HSPC069,Human,Huntingtin yeast partner B,Huntingtin-interacting protein 1,Huntingtin-interacting protein B,HYPB,KIAA1732,KM
EIAAB32199 Fas ligand-associated factor 1,FBP11,FLAF1,FNBP3,Formin-binding protein 11,Formin-binding protein 3,HIP10,HIP-10,Homo sapiens,HSPC225,Human,Huntingtin yeast partner A,Huntingtin-interacting protein 10
orb90171 Lysostaphin protein Lysostaphin, an endopeptidase specific for the cell wall peptidoglycan of staphylococci, is an extremely potent anti-staphylococcal agent. Lysostaphin is used as research and diagn 1 mg
EIAAB39347 Mouse,Mus musculus,Spata24,Spermatogenesis-associated protein 24,TATA-binding protein-like factor-interacting protein,Testis protein T6441 homolog,Tipt,Tipt2,TLF-interacting protein,TRF2-interacting p
EIAAB30770 Homo sapiens,Human,Peptidoglycan recognition protein 4,Peptidoglycan recognition protein I-beta,Peptidoglycan recognition protein intermediate beta,PGLYRP4,PGLYRPIbeta,PGRPIB,PGRP-I-beta,SBBI67


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur