Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Peptidoglycan-recognition protein SB2 (EC 3.5.1.28)

 PGSB2_DROSI             Reviewed;         182 AA.
Q70PW6;
10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
05-JUL-2004, sequence version 1.
25-OCT-2017, entry version 59.
RecName: Full=Peptidoglycan-recognition protein SB2;
EC=3.5.1.28;
Flags: Precursor;
Name=PGRP-SB2;
Drosophila simulans (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila; Sophophora.
NCBI_TaxID=7240;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=14738318; DOI=10.1007/s00239-003-2506-6;
Jiggins F.M., Hurst G.D.D.;
"The evolution of parasite recognition genes in the innate immune
system: purifying selection on Drosophila melanogaster peptidoglycan
recognition proteins.";
J. Mol. Evol. 57:598-605(2003).
-!- FUNCTION: N-acetylmuramyl-L-alanine amidase involved in innate
immunity by degrading bacterial peptidoglycans (PGN). Probably
plays a scavenger role by digesting biologically active PGN into
biologically inactive fragments. Has no direct bacteriolytic
activity (By similarity). {ECO:0000250}.
-!- CATALYTIC ACTIVITY: Hydrolyzes the link between N-acetylmuramoyl
residues and L-amino acid residues in certain cell-wall
glycopeptides.
-!- COFACTOR:
Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
Evidence={ECO:0000250|UniProtKB:Q8INK6};
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
-!- SIMILARITY: Belongs to the N-acetylmuramoyl-L-alanine amidase 2
family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AJ556586; CAD89151.1; -; Genomic_DNA.
ProteinModelPortal; Q70PW6; -.
SMR; Q70PW6; -.
FlyBase; FBgn0068647; Dsim\PGRP-SB2.
OrthoDB; EOG091G0O6Z; -.
GO; GO:0005576; C:extracellular region; ISS:UniProtKB.
GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
GO; GO:0042834; F:peptidoglycan binding; IEA:InterPro.
GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
CDD; cd06583; PGRP; 1.
Gene3D; 3.40.80.10; -; 1.
InterPro; IPR002502; Amidase_domain.
InterPro; IPR036505; Amidase_sf.
InterPro; IPR017331; Peptidoglycan_recognition.
InterPro; IPR015510; PGRP.
InterPro; IPR006619; PGRP_domain_met/bac.
PANTHER; PTHR11022; PTHR11022; 1.
Pfam; PF01510; Amidase_2; 1.
PIRSF; PIRSF037945; PGRPs; 1.
SMART; SM00644; Ami_2; 1.
SMART; SM00701; PGRP; 1.
SUPFAM; SSF55846; SSF55846; 1.
3: Inferred from homology;
Disulfide bond; Glycoprotein; Hydrolase; Immunity; Innate immunity;
Metal-binding; Secreted; Signal; Zinc.
SIGNAL 1 17 {ECO:0000255}.
CHAIN 18 182 Peptidoglycan-recognition protein SB2.
/FTId=PRO_0000023909.
METAL 47 47 Zinc; via pros nitrogen.
{ECO:0000250|UniProtKB:Q8INK6}.
METAL 155 155 Zinc; via pros nitrogen.
{ECO:0000250|UniProtKB:Q8INK6}.
METAL 163 163 Zinc. {ECO:0000250|UniProtKB:Q8INK6}.
SITE 81 81 Important for catalytic activity;
essential for amidase activity and zinc
hydrate coordination.
{ECO:0000250|UniProtKB:P00806}.
CARBOHYD 149 149 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 54 60 {ECO:0000250}.
SEQUENCE 182 AA; 20512 MW; C74D0CEFD5561BC4 CRC64;
MKLQLALVLC GLTLALGQIV PRSSWCPVPI SPRIPRLMVP VRLIIIHHTV TAPCFNPHQC
QLVLRQIRAD HMRRKFRDIG YNFLIGGDGR IYEGLGFGIR GEHAPRYNSQ SIGIAFIGNF
QTGLPPSQML QAARTLIQIA VQRRQVSPNY SLVGHCQTKA TACPGRHLLN ELKKWPRWQP
KP


Related products :

Catalog number Product name Quantity
EIAAB30770 Homo sapiens,Human,Peptidoglycan recognition protein 4,Peptidoglycan recognition protein I-beta,Peptidoglycan recognition protein intermediate beta,PGLYRP4,PGLYRPIbeta,PGRPIB,PGRP-I-beta,SBBI67
EIAAB30768 Gm420,Mouse,Mus musculus,Peptidoglycan recognition protein 3,Peptidoglycan recognition protein I-alpha,Peptidoglycan recognition protein intermediate alpha,Pglyrp3,PGLYRPIalpha,Pgrpia,PGRP-I-alpha
EIAAB30769 Homo sapiens,Human,Peptidoglycan recognition protein 3,Peptidoglycan recognition protein I-alpha,Peptidoglycan recognition protein intermediate alpha,PGLYRP3,PGLYRPIalpha,PGRPIA,PGRP-I-alpha
EIAAB30771 Mouse,Mus musculus,Peptidoglycan recognition protein 4,Peptidoglycan recognition protein I-beta,Peptidoglycan recognition protein intermediate beta,Pglyrp4,PGLYRPIbeta,Pgrpib,PGRP-I-beta
EIAAB30767 Mouse,Mus musculus,N-acetylmuramoyl-L-alanine amidase,Peptidoglycan recognition protein 2,Peptidoglycan recognition protein long,Pglyrp2,Pglyrpl,Pgrpl,PGRP-L,TagL
EIAAB30765 N-acetylmuramoyl-L-alanine amidase,Peptidoglycan recognition protein 2,Peptidoglycan recognition protein long,PGLYRP2,PGRPL,PGRP-L,Pig,Sus scrofa
EIAAB30766 Homo sapiens,Human,N-acetylmuramoyl-L-alanine amidase,Peptidoglycan recognition protein 2,Peptidoglycan recognition protein long,PGLYRP2,PGLYRPL,PGRPL,PGRP-L,UNQ3103_PRO10102
EIAAB30764 Homo sapiens,Human,Peptidoglycan recognition protein 1,Peptidoglycan recognition protein short,PGLYRP,PGLYRP1,PGRP,PGRP-S,SBBI68,TNFSF3L,UNQ639_PRO1269
EIAAB30761 Bos taurus,Bovine,OBP,Oligosaccharide-binding protein,Peptidoglycan recognition protein 1,Peptidoglycan recognition protein short,PGLYRP,PGLYRP1,PGRP,PGRP-S
EIAAB30763 Peptidoglycan recognition protein 1,Peptidoglycan recognition protein short,Pglyrp,Pglyrp1,Pgrp,PGRP-S,Rat,Rattus norvegicus
EIAAB30762 Cytokine tag7,Mouse,Mus musculus,Peptidoglycan recognition protein 1,Peptidoglycan recognition protein short,Pglyrp,Pglyrp1,Pgrp,Pgrps,PGRP-S,Tag7
RPR-597 Recombinant Human Peptidoglycan Recognition Protein 1 2
ER428 Peptidoglycan recognition protein 1 Elisa Kit 96T
EH3565 Peptidoglycan Recognition Protein-S Elisa Kit 96T
EM630 Peptidoglycan recognition protein 3 Elisa Kit 96T
pro-1597 Recombinant Human Peptidoglycan Recognition Protein 1 2
CSB-EL017862RA Rat Peptidoglycan recognition protein 1(PGLYRP1) ELISA kit 96T
E3610h Human Peptidoglycan Recognition Protein 3 ELISA Ki 96T
E0837b Human ELISA Kit FOR Peptidoglycan recognition protein 4 96T
E10634h Human Peptidoglycan Recognition protein 2 ELISA Ki 96T
201-20-4183 PGLYRP3{peptidoglycan recognition protein 3}rabbit.pAb 0.2ml
pro-1597 Recombinant Human Peptidoglycan Recognition Protein 1 10
PGM1 PGLYRP3 Gene peptidoglycan recognition protein 3
PGLYRP3 PGLYRP1 Gene peptidoglycan recognition protein 1
pro-1597 Recombinant Human Peptidoglycan Recognition Protein 1 1mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur