Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Peroxisomal membrane protein 11A (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Peroxisomal coatomer receptor) (Peroxisomal membrane protein 26) (Pmp26p) (Protein PEX11 homolog alpha) (PEX11-alpha) (RnPEX11p)

 PX11A_RAT               Reviewed;         246 AA.
O70597; Q6P749;
26-APR-2005, integrated into UniProtKB/Swiss-Prot.
01-AUG-1998, sequence version 1.
28-FEB-2018, entry version 99.
RecName: Full=Peroxisomal membrane protein 11A;
AltName: Full=28 kDa peroxisomal integral membrane protein;
Short=PMP28;
AltName: Full=Peroxin-11A;
AltName: Full=Peroxisomal biogenesis factor 11A;
AltName: Full=Peroxisomal coatomer receptor;
AltName: Full=Peroxisomal membrane protein 26;
Short=Pmp26p;
AltName: Full=Protein PEX11 homolog alpha;
Short=PEX11-alpha;
AltName: Full=RnPEX11p;
Name=Pex11a; Synonyms=Pex11;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TOPOLOGY, FUNCTION,
MUTAGENESIS OF 242-LYS--LYS-244, AND INTERACTION WITH COPB2 AND COPA.
TISSUE=Liver;
PubMed=9548716; DOI=10.1083/jcb.141.2.373;
Passreiter M., Anton M., Lay D., Frank R., Harter C., Wieland F.T.,
Gorgas K., Just W.W.;
"Peroxisome biogenesis: involvement of ARF and coatomer.";
J. Cell Biol. 141:373-383(1998).
[2]
INDUCTION.
TISSUE=Liver;
PubMed=9714566; DOI=10.1016/S0014-5793(98)00815-1;
Abe I., Okumoto K., Tamura S., Fujiki Y.;
"Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is
encoded by PEX11.";
FEBS Lett. 431:468-472(1998).
[3]
TISSUE SPECIFICITY, AND INDUCTION.
PubMed=9792670; DOI=10.1074/jbc.273.45.29607;
Schrader M., Reuber B.E., Morrell J.C., Jimenez-Sanchez G., Obie C.,
Stroh T.A., Valle D., Schroer T.A., Gould S.J.;
"Expression of PEX11beta mediates peroxisome proliferation in the
absence of extracellular stimuli.";
J. Biol. Chem. 273:29607-29614(1998).
-!- FUNCTION: May be involved in peroxisomal proliferation and may
regulate peroxisomes division. May mediate binding of coatomer
proteins to the peroxisomal membrane (PubMed:9548716). Promotes
membrane protrusion and elongation on the peroxisomal surface.
{ECO:0000250|UniProtKB:O75192, ECO:0000269|PubMed:9548716}.
-!- SUBUNIT: Homodimer (By similarity). Heterodimer with PEX11G (By
similarity). Probably interacts with COPB2 and COPA
(PubMed:9548716). Interacts with PEX19 (By similarity). Interacts
with FIS1 (By similarity). {ECO:0000250|UniProtKB:O75192,
ECO:0000269|PubMed:9548716}.
-!- SUBCELLULAR LOCATION: Peroxisome membrane
{ECO:0000269|PubMed:9548716}; Multi-pass membrane protein
{ECO:0000269|PubMed:9548716}.
-!- TISSUE SPECIFICITY: Expressed at high levels in kidney, liver,
lung, brain, and testis and at low levels in heart, spleen and
skeletal muscle. {ECO:0000269|PubMed:9792670}.
-!- INDUCTION: Induced by clofibrate and di(2-ethylhexyl)phtalate
(DEHP). {ECO:0000269|PubMed:9714566, ECO:0000269|PubMed:9792670}.
-!- SIMILARITY: Belongs to the peroxin-11 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AJ224120; CAA11838.1; -; mRNA.
RefSeq; NP_445939.1; NM_053487.2.
UniGene; Rn.14519; -.
IntAct; O70597; 1.
MINT; O70597; -.
STRING; 10116.ENSRNOP00000020229; -.
PaxDb; O70597; -.
PRIDE; O70597; -.
Ensembl; ENSRNOT00000020229; ENSRNOP00000020229; ENSRNOG00000015003.
GeneID; 85249; -.
KEGG; rno:85249; -.
UCSC; RGD:619842; rat.
CTD; 8800; -.
RGD; 619842; Pex11a.
eggNOG; KOG4186; Eukaryota.
eggNOG; ENOG4111NS6; LUCA.
GeneTree; ENSGT00390000014273; -.
HOGENOM; HOG000251589; -.
HOVERGEN; HBG053771; -.
InParanoid; O70597; -.
KO; K13351; -.
OMA; NLCDILN; -.
OrthoDB; EOG091G0H6Y; -.
PhylomeDB; O70597; -.
TreeFam; TF325704; -.
PRO; PR:O70597; -.
Proteomes; UP000002494; Chromosome 1.
Bgee; ENSRNOG00000015003; -.
Genevisible; O70597; RN.
GO; GO:0005779; C:integral component of peroxisomal membrane; ISS:UniProtKB.
GO; GO:0005778; C:peroxisomal membrane; IDA:HGNC.
GO; GO:0005777; C:peroxisome; ISO:RGD.
GO; GO:0043234; C:protein complex; ISO:RGD.
GO; GO:0042803; F:protein homodimerization activity; ISO:RGD.
GO; GO:0050873; P:brown fat cell differentiation; ISO:RGD.
GO; GO:0016559; P:peroxisome fission; ISO:RGD.
GO; GO:0016557; P:peroxisome membrane biogenesis; IDA:RGD.
GO; GO:0007031; P:peroxisome organization; ISS:UniProtKB.
GO; GO:0044375; P:regulation of peroxisome size; ISO:RGD.
GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
InterPro; IPR008733; PEX11.
Pfam; PF05648; PEX11; 1.
1: Evidence at protein level;
Complete proteome; Membrane; Peroxisome; Peroxisome biogenesis;
Reference proteome; Transmembrane; Transmembrane helix.
CHAIN 1 246 Peroxisomal membrane protein 11A.
/FTId=PRO_0000105966.
TOPO_DOM 1 93 Cytoplasmic. {ECO:0000255}.
TRANSMEM 94 114 Helical. {ECO:0000255}.
TOPO_DOM 115 217 Lumenal. {ECO:0000255}.
TRANSMEM 218 238 Helical. {ECO:0000255}.
TOPO_DOM 239 246 Cytoplasmic. {ECO:0000255}.
REGION 218 238 Required for homodimerization,
interaction with PEX11G, and peroxisomal
localization.
{ECO:0000250|UniProtKB:O75192}.
MUTAGEN 242 244 KLK->SLS: Loss of interactions with COPA
and COPB2. {ECO:0000269|PubMed:9548716}.
MUTAGEN 244 244 K->S: Loss of interactions with COPA and
COPB2.
SEQUENCE 246 AA; 27923 MW; A4D1951ADE21B04E CRC64;
MDAFIRVANQ SQGRDRLFRA TQHACMLLRY LLESKAGKEA VVTKLKNLET SVSTGRKWFR
LGNVLHAIQA TEQSIQATDL VPRLCLTLAN LNRVVYYICD TVLWAKSVGL TSGINREKWQ
MRAARHYYYF LLLSLVRDLY EVLLHMGQVA RDRAKREKSS GDPPKYSVAN EESEWLQSFL
LLLFQSLKRN PPLFLDTVKN FCDILIPLNQ LGIYKSNLGV VGFGGLVSSV AGLITVVYPQ
LKLKAR


Related products :

Catalog number Product name Quantity
EIAAB33230 28 kDa peroxisomal integral membrane protein,Homo sapiens,HsPEX11p,Human,Peroxin-11A,Peroxisomal biogenesis factor 11A,Peroxisomal membrane protein 11A,PEX11,PEX11A,PEX11-alpha,PMP28,Protein PEX11 hom
EIAAB33227 28 kDa peroxisomal integral membrane protein,Peroxin-11A,Peroxisomal biogenesis factor 11A,Peroxisomal coatomer receptor,Peroxisomal membrane protein 11A,Peroxisomal membrane protein 26,Pex11,Pex11a,P
EIAAB33228 Mouse,Mus musculus,Peroxin-11A,Peroxisomal biogenesis factor 11A,Peroxisomal membrane protein 11A,Pex11a,PEX11-alpha,Protein PEX11 homolog alpha
EIAAB33234 Homo sapiens,Human,Peroxin-11C,Peroxisomal biogenesis factor 11C,Peroxisomal membrane protein 11C,PEX11C,PEX11G,PEX11-gamma,Protein PEX11 homolog gamma
EIAAB33233 Homo sapiens,Human,Peroxin-11B,Peroxisomal biogenesis factor 11B,Peroxisomal membrane protein 11B,PEX11B,PEX11-beta,Protein PEX11 homolog beta
EIAAB33235 Mouse,Mus musculus,Peroxin-11C,Peroxisomal biogenesis factor 11C,Peroxisomal membrane protein 11C,Pex11c,Pex11g,PEX11-gamma,Protein PEX11 homolog gamma
EIAAB33232 Mouse,Mus musculus,Peroxin-11B,Peroxisomal biogenesis factor 11B,Peroxisomal membrane protein 11B,Pex11b,PEX11-beta,Protein PEX11 homolog beta
EIAAB33231 Bos taurus,Bovine,Peroxin-11B,Peroxisomal biogenesis factor 11B,Peroxisomal membrane protein 11B,PEX11B
EIAAB33229 Bos taurus,Bovine,Peroxin-11A,Peroxisomal biogenesis factor 11A,Peroxisomal membrane protein 11A,PEX11A
EIAAB30620 35 kDa peroxisomal membrane protein,Homo sapiens,Human,PAF1,PAF-1,Peroxin-2,Peroxisomal membrane protein 3,Peroxisome assembly factor 1,Peroxisome biogenesis factor 2,PEX2,PMP3,PMP35,PXMP3,RING finger
EIAAB30613 Homo sapiens,Human,Peroxin-16,Peroxisomal biogenesis factor 16,Peroxisomal membrane protein PEX16,PEX16
EIAAB30611 Bos taurus,Bovine,Peroxin-16,Peroxisomal biogenesis factor 16,Peroxisomal membrane protein PEX16,PEX16
EIAAB30612 Mouse,Mus musculus,Peroxin-16,Peroxisomal biogenesis factor 16,Peroxisomal membrane protein PEX16,Pex16
EIAAB30610 Homo sapiens,Human,Peroxin-14,Peroxisomal membrane anchor protein PEX14,Peroxisomal membrane protein PEX14,PEX14,PTS1 receptor-docking protein
EIAAB30609 Peroxin-14,Peroxisomal membrane anchor protein PEX14,Peroxisomal membrane protein PEX14,Pex14,PTS1 receptor-docking protein,Rat,Rattus norvegicus
EIAAB30608 Mouse,Mus musculus,Peroxin-14,Peroxisomal membrane anchor protein PEX14,Peroxisomal membrane protein PEX14,Pex14,PTS1 receptor-docking protein
EIAAB33253 24 kDa peroxisomal intrinsic membrane protein,Homo sapiens,Human,Peroxisomal membrane protein 4,PMP24,PXMP4
EIAAB30615 Bos taurus,Bovine,Peroxin-19,Peroxisomal biogenesis factor 19,Peroxisomal farnesylated protein,PEX19,PXF
EIAAB30614 Mouse,Mus musculus,Peroxin-19,Peroxisomal biogenesis factor 19,Peroxisomal farnesylated protein,Pex19,PxF,Pxf
EIAAB30616 Peroxin-19,Peroxisomal biogenesis factor 19,Peroxisomal farnesylated protein,Pex19,Pxf,Rat,Rattus norvegicus
EIAAB33250 24 kDa peroxisomal intrinsic membrane protein,Mouse,Mus musculus,Peroxisomal membrane protein 4,Pmp24,Pxmp4
EIAAB33248 22 kDa peroxisomal membrane protein,Homo sapiens,Human,Peroxisomal membrane protein 2,PMP22,PXMP2
EIAAB33252 24 kDa peroxisomal intrinsic membrane protein,Peroxisomal membrane protein 4,Pmp24,Pxmp4,Rat,Rattus norvegicus
15-288-22267F Peroxisomal biogenesis factor 19 - Peroxin-19; Peroxisomal farnesylated protein; 33 kDa housekeeping protein Polyclonal 0.1 mg
15-288-22267F Peroxisomal biogenesis factor 19 - Peroxin-19; Peroxisomal farnesylated protein; 33 kDa housekeeping protein Polyclonal 0.05 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur