Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Phytol kinase (EC 2.7.1.182)

 PHYK_SYNY3              Reviewed;         233 AA.
P74653;
01-APR-2015, integrated into UniProtKB/Swiss-Prot.
01-FEB-1997, sequence version 1.
05-DEC-2018, entry version 92.
RecName: Full=Phytol kinase {ECO:0000303|PubMed:16361393};
EC=2.7.1.182 {ECO:0000269|PubMed:16361393};
Name=vte5 {ECO:0000303|PubMed:16361393};
OrderedLocusNames=slr1652 {ECO:0000312|EMBL:BAA18769.1};
Synechocystis sp. (strain PCC 6803 / Kazusa).
Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae;
Synechocystis.
NCBI_TaxID=1111708;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=PCC 6803 / Kazusa;
PubMed=8905231; DOI=10.1093/dnares/3.3.109;
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T.,
Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S.,
Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M.,
Tabata S.;
"Sequence analysis of the genome of the unicellular cyanobacterium
Synechocystis sp. strain PCC6803. II. Sequence determination of the
entire genome and assignment of potential protein-coding regions.";
DNA Res. 3:109-136(1996).
[2]
FUNCTION, CATALYTIC ACTIVITY, SUBSTRATE SPECIFICITY, DISRUPTION
PHENOTYPE, AND PATHWAY.
STRAIN=ATCC 27184 / PCC 6803 / N-1;
PubMed=16361393; DOI=10.1105/tpc.105.037077;
Valentin H.E., Lincoln K., Moshiri F., Jensen P.K., Qi Q.,
Venkatesh T.V., Karunanandaa B., Baszis S.R., Norris S.R., Savidge B.,
Gruys K.J., Last R.L.;
"The Arabidopsis vitamin E pathway gene5-1 mutant reveals a critical
role for phytol kinase in seed tocopherol biosynthesis.";
Plant Cell 18:212-224(2006).
[3]
FUNCTION, AND DISRUPTION PHENOTYPE.
STRAIN=ATCC 27184 / PCC 6803 / N-1;
PubMed=17499209; DOI=10.1016/j.bbabio.2007.03.010;
Vavilin D., Vermaas W.;
"Continuous chlorophyll degradation accompanied by chlorophyllide and
phytol reutilization for chlorophyll synthesis in Synechocystis sp.
PCC 6803.";
Biochim. Biophys. Acta 1767:920-929(2007).
-!- FUNCTION: Catalyzes the CTP-dependent phosphorylation of phytol to
phytylmonophosphate (PMP). Can also use UTP as an alternative
phosphate donor, but not ATP or GTP. Is involved in tocopherol
biosynthesis, via the utilization of phytol generated by
chlorophyll degradation (PubMed:16361393). Also plays a
significant but not critical role in the recycling of phytol for
the biosynthesis of new chlorophyll molecules (PubMed:17499209).
{ECO:0000269|PubMed:16361393, ECO:0000269|PubMed:17499209}.
-!- CATALYTIC ACTIVITY:
Reaction=CTP + phytol = CDP + H(+) + phytyl phosphate;
Xref=Rhea:RHEA:38055, ChEBI:CHEBI:15378, ChEBI:CHEBI:17327,
ChEBI:CHEBI:37563, ChEBI:CHEBI:58069, ChEBI:CHEBI:75483;
EC=2.7.1.182; Evidence={ECO:0000269|PubMed:16361393};
-!- PATHWAY: Cofactor biosynthesis; tocopherol biosynthesis.
{ECO:0000269|PubMed:16361393}.
-!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Multi-pass
membrane protein {ECO:0000255}.
-!- DISRUPTION PHENOTYPE: Cells lacking this gene show a reduction in
tocopherol levels by 50% or more, and an accumulation of free
phytol (PubMed:16361393). When measuring the kinetics of
chlorophyll labeling after adding 13C, the mutant cells show a
similar rate of chlorophyll synthesis and degradation as the wild
type, but show a reduced rate of accumulation of chlorophyll
containing labeled porphyrin/unlabeled phytyl (13Por12Phy)
(PubMed:17499209). {ECO:0000269|PubMed:16361393,
ECO:0000269|PubMed:17499209}.
-!- SIMILARITY: Belongs to the polyprenol kinase family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; BA000022; BAA18769.1; -; Genomic_DNA.
PIR; S76857; S76857.
IntAct; P74653; 1.
STRING; 1148.SYNGTS_3063; -.
SwissLipids; SLP:000001497; -.
PaxDb; P74653; -.
EnsemblBacteria; BAA18769; BAA18769; BAA18769.
KEGG; syn:slr1652; -.
HOGENOM; HOG000233257; -.
InParanoid; P74653; -.
KO; K18678; -.
OMA; MAWGDGL; -.
PhylomeDB; P74653; -.
BRENDA; 2.7.1.182; 382.
UniPathway; UPA00160; -.
Proteomes; UP000001425; Chromosome.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO; GO:0010276; F:phytol kinase activity; IDA:UniProtKB.
GO; GO:0033306; P:phytol metabolic process; IDA:UniProtKB.
GO; GO:0010189; P:vitamin E biosynthetic process; IMP:UniProtKB.
InterPro; IPR032974; Polypren_kinase.
PANTHER; PTHR13205; PTHR13205; 1.
1: Evidence at protein level;
Cell membrane; Complete proteome; Kinase; Membrane;
Nucleotide-binding; Reference proteome; Transferase; Transmembrane;
Transmembrane helix.
CHAIN 1 233 Phytol kinase.
/FTId=PRO_0000432651.
TRANSMEM 9 29 Helical. {ECO:0000255}.
TRANSMEM 56 76 Helical. {ECO:0000255}.
TRANSMEM 96 118 Helical. {ECO:0000255}.
TRANSMEM 122 144 Helical. {ECO:0000255}.
TRANSMEM 172 192 Helical. {ECO:0000255}.
TRANSMEM 213 233 Helical. {ECO:0000255}.
SEQUENCE 233 AA; 24737 MW; 19C8EBF4272F08B2 CRC64;
MGIEQNNPMA LPLWIAVGLA ATYLGAVVLT AELLNRLSLS PAEVTRKIVH IGAGQVVLIA
WWLSIPGWVG AIAGVFAAGI AVLSYRLPIL PSLESVGRHS YGTLFYALSI GLLVGGFFSL
GLPIFAAIGI LVMAWGDGLA ALVGQRWGRH RYQVFGFRKS WEGTLTMVLA SFLVTVVFLS
YTFGFTVIVL VVAGTVAIAS AGLESFSRWG IDNLTVPLGS ALIAWAGSYL WLG


Related products :

Catalog number Product name Quantity
7541-49-3 Phytol Phytol natural isomer 1g
150-86-7 Phytol synthetic 1g
P18640 Phytol 90-95 percent mixture of isomers 25 G
P18640 Phytol 90_95 percent mixture of isomers 25 G
EIAAB24784 GCK family kinase MiNK,Map4k6,MAPK_ERK kinase kinase kinase 6,MEK kinase kinase 6,MEKKK 6,Mink,Mink1,Misshapen_NIK-related kinase,Misshapen-like kinase 1,Mitogen-activated protein kinase kinase kinase
EIAAB24783 GCK family kinase MiNK,Map4k6,MAPK_ERK kinase kinase kinase 6,MEK kinase kinase 6,MEKKK 6,Mink,Mink1,Misshapen_NIK-related kinase,Misshapen-like kinase 1,Mitogen-activated protein kinase kinase kinase
EIAAB25244 c-Jun N-terminal kinase kinase 2,Dual specificity mitogen-activated protein kinase kinase 7,JNK kinase 2,JNK-activating kinase 2,JNKK 2,MAP kinase kinase 7,Map2k7,MAPK_ERK kinase 7,MAPKK 7,MEK 7,Mkk7,
EIAAB25239 C-JUN N-terminal kinase kinase 1,Dual specificity mitogen-activated protein kinase kinase 4,JNK kinase 1,JNK-activating kinase 1,JNKK 1,Jnkk1,MAP kinase kinase 4,Map2k4,MAPK_ERK kinase 4,MAPKK 4,MEK 4
EIAAB25245 c-Jun N-terminal kinase kinase 2,Dual specificity mitogen-activated protein kinase kinase 7,JNK kinase 2,JNK-activating kinase 2,JNKK 2,MAP kinase kinase 7,Map2k7,MAPK_ERK kinase 7,MAPKK 7,MEK 7,Rat,R
EIAAB25246 c-Jun N-terminal kinase kinase 2,Dual specificity mitogen-activated protein kinase kinase 7,Homo sapiens,Human,JNK kinase 2,JNK-activating kinase 2,JNKK 2,JNKK2,MAP kinase kinase 7,MAP2K7,MAPK_ERK kin
EIAAB25240 c-Jun N-terminal kinase kinase 1,Dual specificity mitogen-activated protein kinase kinase 4,Homo sapiens,Human,JNK-activating kinase 1,JNKK,JNKK1,MAP kinase kinase 4,MAP2K4,MAPK_ERK kinase 4,MAPKK 4,M
E1358m ELISA Apoptosis signal-regulating kinase 1,Ask1,ASK-1,Map3k5,MAPK_ERK kinase kinase 5,MEK kinase 5,MEKK 5,Mekk5,Mitogen-activated protein kinase kinase kinase 5,Mouse,Mus musculus 96T
U1358m CLIA Apoptosis signal-regulating kinase 1,Ask1,ASK-1,Map3k5,MAPK_ERK kinase kinase 5,MEK kinase 5,MEKK 5,Mekk5,Mitogen-activated protein kinase kinase kinase 5,Mouse,Mus musculus 96T
E1358m ELISA kit Apoptosis signal-regulating kinase 1,Ask1,ASK-1,Map3k5,MAPK_ERK kinase kinase 5,MEK kinase 5,MEKK 5,Mekk5,Mitogen-activated protein kinase kinase kinase 5,Mouse,Mus musculus 96T
EIAAB24782 B55,GCK family kinase MiNK,Homo sapiens,Human,MAP4K6,MAPK_ERK kinase kinase kinase 6,MEK kinase kinase 6,MEKKK 6,MINK,MINK1,Misshapen_NIK-related kinase,Misshapen-like kinase 1,Mitogen-activated prote
E1358h ELISA Apoptosis signal-regulating kinase 1,ASK1,ASK-1,Homo sapiens,Human,MAP3K5,MAPK_ERK kinase kinase 5,MAPKKK5,MEK kinase 5,MEKK 5,MEKK5,Mitogen-activated protein kinase kinase kinase 5 96T
E1358h ELISA kit Apoptosis signal-regulating kinase 1,ASK1,ASK-1,Homo sapiens,Human,MAP3K5,MAPK_ERK kinase kinase 5,MAPKKK5,MEK kinase 5,MEKK 5,MEKK5,Mitogen-activated protein kinase kinase kinase 5 96T
U1358h CLIA Apoptosis signal-regulating kinase 1,ASK1,ASK-1,Homo sapiens,Human,MAP3K5,MAPK_ERK kinase kinase 5,MAPKKK5,MEK kinase 5,MEKK 5,MEKK5,Mitogen-activated protein kinase kinase kinase 5 96T
18-662-20092 Dual specificity mitogen-activated protein kinase kinase 1 - EC 2.7.12.2; MAP kinase kinase 1; MAPKK 1; ERK activator kinase 1; MAPK_ERK kinase 1; MEK1 Polyclonal 0.1 ml
15-288-21068 Dual specificity mitogen-activated protein kinase kinase 1 - EC 2.7.12.2; MAP kinase kinase 1; MAPKK 1; ERK activator kinase 1; MAPK_ERK kinase 1; MEK1 Polyclonal 0.1 mg
15-288-21068 Dual specificity mitogen-activated protein kinase kinase 1 - EC 2.7.12.2; MAP kinase kinase 1; MAPKK 1; ERK activator kinase 1; MAPK_ERK kinase 1; MEK1 Polyclonal 0.05 mg
18-662-20091 Dual specificity mitogen-activated protein kinase kinase 1 - EC 2.7.12.2; MAP kinase kinase 1; MAPKK 1; ERK activator kinase 1; MAPK_ERK kinase 1; MEK1 Polyclonal 0.1 ml
18-662-20090 Dual specificity mitogen-activated protein kinase kinase 1 - EC 2.7.12.2; MAP kinase kinase 1; MAPKK 1; ERK activator kinase 1; MAPK_ERK kinase 1; MEK1 Polyclonal 0.1 ml
18-785-210403 SEK1_MKK4 (Phospho-Thr261) - EC 2.7.12.2; MAP kinase kinase 4; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; JNKK; SAPK_ERK kinase 1; SEK1 Polyclonal 0.05 mg
18-785-210404 SEK1_MKK4 (Phospho-Ser80) - EC 2.7.12.2; MAP kinase kinase 4; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; JNKK; SAPK_ERK kinase 1; SEK1 Polyclonal 0.05 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur