Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

 Q10UL6_9INFA            Unreviewed;       759 AA.
Q10UL6;
22-AUG-2006, integrated into UniProtKB/TrEMBL.
22-AUG-2006, sequence version 1.
25-APR-2018, entry version 61.
RecName: Full=Polymerase basic protein 2 {ECO:0000256|HAMAP-Rule:MF_04062, ECO:0000256|RuleBase:RU361246, ECO:0000256|SAAS:SAAS00943514};
AltName: Full=RNA-directed RNA polymerase subunit P3 {ECO:0000256|HAMAP-Rule:MF_04062};
Name=PB2 {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|RuleBase:RU361246, ECO:0000313|EMBL:ABG47883.1};
Influenza A virus (A/New York/684/1995(H3N2)).
Viruses; ssRNA viruses; ssRNA negative-strand viruses;
Orthomyxoviridae; Alphainfluenzavirus.
NCBI_TaxID=383025 {ECO:0000313|EMBL:ABG47883.1};
[1] {ECO:0000313|EMBL:ABG47883.1}
NUCLEOTIDE SEQUENCE.
STRAIN=A/New York/684/1995 {ECO:0000313|EMBL:ABG47883.1};
The NIAID Influenza Genome Sequencing Consortium;
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:ABG47883.1}
NUCLEOTIDE SEQUENCE.
STRAIN=A/New York/684/1995 {ECO:0000313|EMBL:ABG47883.1};
Ghedin E., Miller N., Zaborsky J., Feldblyum T., Subbu V., Shumway M.,
Sitz J., Kosack D., Koo H., Salzberg S.L., Griesemer S., StGeorge K.,
Bennett R., Taylor J., Bao Y., Bolotov P., Dernovoy D., Lipman D.J.,
Tatusova T.;
"The NIAID Influenza Genome Sequencing Project.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
-!- SUBCELLULAR LOCATION: Host nucleus
{ECO:0000256|SAAS:SAAS00943502}.
-!- SIMILARITY: Belongs to the influenza viruses PB2 family.
{ECO:0000256|HAMAP-Rule:MF_04062, ECO:0000256|RuleBase:RU361246,
ECO:0000256|SAAS:SAAS00943527}.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|HAMAP-Rule:MF_04062}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; CY011831; ABG47883.1; -; Genomic_RNA.
GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-UniRule.
GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO; GO:0019012; C:virion; IEA:UniProtKB-UniRule.
GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-UniRule.
GO; GO:0075526; P:cap snatching; IEA:UniProtKB-UniRule.
GO; GO:0039545; P:suppression by virus of host MAVS activity; IEA:UniProtKB-UniRule.
GO; GO:0039523; P:suppression by virus of host RNA polymerase II activity; IEA:UniProtKB-UniRule.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
Gene3D; 3.30.30.90; -; 1.
HAMAP; MF_04062; INV_PB2; 1.
InterPro; IPR001591; INV_PB2.
InterPro; IPR037258; PDB2_C.
Pfam; PF00604; Flu_PB2; 1.
ProDom; PD001667; RNA_pol_PB2_orthomyxovir; 1.
SUPFAM; SSF160453; SSF160453; 1.
3: Inferred from homology;
Cap snatching {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|SAAS:SAAS00943529};
Eukaryotic host gene expression shutoff by virus {ECO:0000256|HAMAP-
Rule:MF_04062, ECO:0000256|SAAS:SAAS00943508};
Eukaryotic host transcription shutoff by virus {ECO:0000256|HAMAP-
Rule:MF_04062, ECO:0000256|SAAS:SAAS00943508};
Host gene expression shutoff by virus {ECO:0000256|HAMAP-
Rule:MF_04062, ECO:0000256|SAAS:SAAS00943508};
Host mitochondrion {ECO:0000256|HAMAP-Rule:MF_04062};
Host nucleus {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|RuleBase:RU361246, ECO:0000256|SAAS:SAAS00943496};
Host-virus interaction {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|SAAS:SAAS00943508};
Inhibition of host innate immune response by virus {ECO:0000256|HAMAP-
Rule:MF_04062};
Inhibition of host MAVS by virus {ECO:0000256|HAMAP-Rule:MF_04062};
Inhibition of host RLR pathway by virus {ECO:0000256|HAMAP-
Rule:MF_04062};
Inhibition of host RNA polymerase II by virus {ECO:0000256|HAMAP-
Rule:MF_04062, ECO:0000256|SAAS:SAAS00943508};
mRNA capping {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|RuleBase:RU361246, ECO:0000256|SAAS:SAAS00943498};
mRNA processing {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|RuleBase:RU361246, ECO:0000256|SAAS:SAAS00943498};
Viral immunoevasion {ECO:0000256|HAMAP-Rule:MF_04062};
Viral transcription {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|SAAS:SAAS00943507};
Virion {ECO:0000256|HAMAP-Rule:MF_04062,
ECO:0000256|RuleBase:RU361246, ECO:0000256|SAAS:SAAS00943495}.
MOTIF 736 739 Nuclear localization signal.
{ECO:0000256|HAMAP-Rule:MF_04062}.
SITE 627 627 Mammalian adaptation. {ECO:0000256|HAMAP-
Rule:MF_04062}.
SEQUENCE 759 AA; 86073 MW; 64051DD22A1728B5 CRC64;
MERIKELRNL MSQSRTREIL TKTTVDHMAI IKKYTSGRQE KNPSLRMKWM MAMKYPITAD
KRITEMVPER NEQGQTLWSK MSDAGSDRVM VSPLAVTWWN RNGPVTNTVH YPKVYKTYFD
KVERLKHGTF GPVHFRNQVK IRRRVDINPG HADLSAKEAQ DVIMEVVFPN EVGARILTSE
SQLTITKEKK EELRDCKISP LMVAYMLERE LVRKTRFLPV AGGTSSIYIE VLHLTQGTCW
EQMYTPGGEV RNDDVDQSLI IAARNIVRRA AVSADPLASL LEMCHSTQIG GTRMVDILRQ
NPTEEQAVDI CKAAMGLRIS SSFSFGGFTF KRTSGSSVKK EEEMLTGNLQ TLKIRVHEGY
EEFTMVGKRA TAILRKATRR LVQLIVSGRD EQSIAEAIIV AMVFSQEDCM IKAVRGDLNF
VNRANQRLNP MHQLLRHFQK DAKVLFQNWG IEHIDNVMGM VGVLPDMTPS TEMSMRGIRV
SKMGVDEYSS TERVVVSIDR FLRVRDQRGN VLLSPEEVSE TQGTERLTIT YSSSMMWEIN
GPESVLVNTY QWIIRNWETV KIQWSQNPAM LYNKMEFEPF QSLVPKAIRG QYSGFVRALF
QQMRDVLGTF DTTQIIKLLP FAAAPPKQSR MQFSSLTVNV RGSGMRILVR GNSPVFNYNK
TTKRLTILGK DAGTLTEDPD ESTSGVESAV LRGFLILGKE DRRYGPALSI NELSNLAKGE
KANVLIGQGD VVLVMKRKRD SSILTDSQTA TKRIRMAIN


Related products :

Catalog number Product name Quantity
EIAAB35736 A190,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Homo sapiens,Human,POLR1A,RNA polymerase I 194 kDa subunit,RNA pol
EIAAB35784 DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,Homo sapiens,Human,POLR2,POLR2A,RNA polymerase II subunit B1,RNA-di
EIAAB35785 DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,Mouse,Mus musculus,Polr2a,RNA polymerase II subunit B1,Rpii215,Rpo2
EIAAB35812 C128,DNA-directed RNA polymerase III 127.6 kDa polypeptide,DNA-directed RNA polymerase III subunit B,DNA-directed RNA polymerase III subunit RPC2,Homo sapiens,Human,POLR3B,RNA polymerase III subunit C
EIAAB35792 DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,DNA-directed RNA polymerase II subunit RPB2,Homo sapiens,Human,POLR2B,RNA polymerase II subunit 2,RNA polyme
EIAAB35794 A-152E5.7,DNA-directed RNA polymerase II 33 kDa polypeptide,DNA-directed RNA polymerase II subunit C,DNA-directed RNA polymerase II subunit RPB3,Homo sapiens,Human,POLR2C,RNA polymerase II subunit 3,R
EIAAB35735 A194,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Polr1a,Rat,Rattus norvegicus,RNA polymerase I 194 kDa subunit,RNA
EIAAB35737 DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Mouse,Mus musculus,Polr1a,RNA polymerase I 194 kDa subunit,RNA polymera
EIAAB35808 DNA-directed RNA polymerase III largest subunit,DNA-directed RNA polymerase III subunit A,DNA-directed RNA polymerase III subunit RPC1,Homo sapiens,Human,POLR3A,RNA polymerase III 155 kDa subunit,RNA
EIAAB35791 DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,DNA-directed RNA polymerase II subunit RPB2,Mouse,Mus musculus,Polr2b,RNA polymerase II subunit 2,RNA polyme
EIAAB35813 C128,DNA-directed RNA polymerase III 127.6 kDa polypeptide,DNA-directed RNA polymerase III subunit B,DNA-directed RNA polymerase III subunit RPC2,Mouse,Mus musculus,Polr3b,RNA polymerase III subunit C
EIAAB35793 DNA-directed RNA polymerase II 33 kDa polypeptide,DNA-directed RNA polymerase II subunit C,DNA-directed RNA polymerase II subunit RPB3,Mouse,Mus musculus,Polr2c,RNA polymerase II subunit 3,RNA polymer
EIAAB35809 DNA-directed RNA polymerase III subunit K,DNA-directed RNA polymerase III subunit RPC10,Homo sapiens,hRPC11,HsC11p,Human,My010,POLR3K,RNA polymerase III 12.5 kDa subunit,RNA polymerase III subunit C10
EIAAB35820 BN51,BN51T,DNA-directed RNA polymerase III subunit D,DNA-directed RNA polymerase III subunit RPC4,Homo sapiens,Human,POLR3D,Protein BN51,RNA polymerase III 47 kDa subunit,RNA polymerase III subunit C4
EIAAB35750 DNA-directed RNA polymerase I subunit E,DNA-directed RNA polymerase I subunit RPA49,Homo sapiens,Human,PAF53,POLR1E,PRAF1,RNA polymerase I subunit A49,RNA polymerase I-associated factor 1,RNA polymera
EIAAB35833 DNA-directed RNA polymerase III subunit H,DNA-directed RNA polymerase III subunit RPC8,Homo sapiens,Human,KIAA1665,POLR3H,RNA polymerase III subunit 22.9 kDa subunit,RNA polymerase III subunit C8,RPC2
EIAAB35749 DNA-directed RNA polymerase I subunit E,DNA-directed RNA polymerase I subunit RPA49,Mouse,Mus musculus,Paf53,Polr1e,Praf1,RNA polymerase I subunit A49,RNA polymerase I-associated factor 1,RNA polymera
EIAAB35787 DNA-directed RNA polymerase II subunit J-1,DNA-directed RNA polymerase II subunit RPB11-a,Homo sapiens,Human,POLR2J,POLR2J1,RNA polymerase II 13.3 kDa subunit,RNA polymerase II subunit B11-a,RPB11a
EIAAB35832 Bos taurus,Bovine,DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide,DNA-directed RNA polymerase III subunit H,DNA-directed RNA polymerase III subunit RPC8,POLR3H,RNA polymerase III subunit
EIAAB35815 DNA-directed RNA polymerase III subunit C,DNA-directed RNA polymerase III subunit RPC3,Homo sapiens,Human,POLR3C,RNA polymerase III 62 kDa subunit,RNA polymerase III subunit C3,RPC62
EIAAB35825 DNA-directed RNA polymerase III subunit F,DNA-directed RNA polymerase III subunit RPC6,Homo sapiens,Human,POLR3F,RNA polymerase III 39 kDa subunit,RNA polymerase III subunit C6,RPC39
EIAAB35802 DNA-directed RNA polymerase II subunit I,DNA-directed RNA polymerase II subunit RPB9,Homo sapiens,Human,POLR2I,RNA polymerase II 14.5 kDa subunit,RNA polymerase II subunit B9,RPB14.5
EIAAB35796 DNA-directed RNA polymerase II subunit D,DNA-directed RNA polymerase II subunit RPB4,Homo sapiens,Human,POLR2D,RNA polymerase II 16 kDa subunit,RNA polymerase II subunit B4,RPB16
EIAAB35786 DNA-directed RNA polymerase II subunit J,DNA-directed RNA polymerase II subunit RPB11,Mouse,Mus musculus,Polr2j,RNA polymerase II 13.3 kDa subunit,RNA polymerase II subunit B11,RPB14,Rpo2-4
EIAAB35827 DNA-directed RNA polymerase III subunit G,DNA-directed RNA polymerase III subunit RPC7,Homo sapiens,Human,POLR3G,RNA polymerase III 32 kDa subunit,RNA polymerase III subunit C7,RPC32


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur