Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Polyprotein pp220 (220 kDa polyprotein) [Cleaved into: p34; p14; p37; p150]

 PP220_ASFB7             Reviewed;        2475 AA.
Q08358; Q65287;
30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
23-JAN-2007, sequence version 3.
25-OCT-2017, entry version 66.
RecName: Full=Polyprotein pp220;
AltName: Full=220 kDa polyprotein;
Contains:
RecName: Full=p34;
Contains:
RecName: Full=p14;
Contains:
RecName: Full=p37;
Contains:
RecName: Full=p150;
Flags: Precursor;
OrderedLocusNames=Ba71V-92; ORFNames=CP2475L;
African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
(ASFV).
Viruses; dsDNA viruses, no RNA stage; Asfarviridae; Asfivirus.
NCBI_TaxID=10498;
NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
NCBI_TaxID=9823; Sus scrofa (Pig).
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEOLYTIC PROCESSING OF
POLYPROTEIN, AND MYRISTOYLATION AT GLY-2.
PubMed=8335009;
Simon-Mateo C., Andres G., Vinuela E.;
"Polyprotein processing in African swine fever virus: a novel gene
expression strategy for a DNA virus.";
EMBO J. 12:2977-2987(1993).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=11831707; DOI=10.1006/viro.1995.1149;
Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
Rodriguez J.F., Vinuela E.;
"Analysis of the complete nucleotide sequence of African swine fever
virus.";
Virology 208:249-278(1995).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 391-808.
PubMed=3245132; DOI=10.1007/BF00572708;
Lopez-Otin C., Simon C., Mendez E., Vinuela E.;
"Mapping and sequence of the gene encoding protein p37, a major
structural protein of African swine fever virus.";
Virus Genes 1:291-303(1988).
[4]
FUNCTION, AND SUBCELLULAR LOCATION OF POLYPROTEIN PP220.
PubMed=9032369;
Andres G., Simon-Mateo C., Vinuela E.;
"Assembly of African swine fever virus: role of polyprotein pp220.";
J. Virol. 71:2331-2341(1997).
[5]
FUNCTION OF POLYPROTEIN PP220.
PubMed=11861832; DOI=10.1128/JVI.76.6.2654-2666.2002;
Andres G., Garcia-Escudero R., Salas M.L., Rodriguez J.M.;
"Repression of African swine fever virus polyprotein pp220-encoding
gene leads to the assembly of icosahedral core-less particles.";
J. Virol. 76:2654-2666(2002).
[6]
SUBCELLULAR LOCATION.
PubMed=12438573; DOI=10.1128/JVI.76.24.12473-12482.2002;
Andres G., Alejo A., Salas J., Salas M.L.;
"African swine fever virus polyproteins pp220 and pp62 assemble into
the core shell.";
J. Virol. 76:12473-12482(2002).
[7]
SUBCELLULAR LOCATION OF P150 AND P34.
PubMed=12525602; DOI=10.1128/JVI.77.3.1682-1690.2003;
Heath C.M., Windsor M., Wileman T.;
"Membrane association facilitates the correct processing of pp220
during production of the major matrix proteins of African swine fever
virus.";
J. Virol. 77:1682-1690(2003).
[8]
SUBCELLULAR LOCATION OF P37.
PubMed=17580096; DOI=10.1016/j.virusres.2007.05.009;
Eulalio A., Nunes-Correia I., Salas J., Salas M.L., Simoes S.,
Pedroso de Lima M.C.;
"African swine fever virus p37 structural protein is localized in
nuclear foci containing the viral DNA at early post-infection times.";
Virus Res. 130:18-27(2007).
-!- FUNCTION: Polyprotein pp220 is essential for the core assembly.
Its myristoyl moiety may function as a membrane-anchoring signal
to bind the developing core shell to the inner viral envelope.
-!- FUNCTION: The structural protein p34 is a component of the virus
core shell.
-!- FUNCTION: The structural protein p14 is a component of the virus
core shell.
-!- FUNCTION: The structural protein p37 is a component of the virus
core shell.
-!- FUNCTION: The structural protein p150 is a component of the virus
core shell.
-!- SUBCELLULAR LOCATION: Polyprotein pp220: Host cytoplasm, host
perinuclear region. Note=Found in perinuclear cytoplasmic viral
factories during assembly.
-!- SUBCELLULAR LOCATION: p34: Virion {ECO:0000305}. Host cytoplasm,
host perinuclear region {ECO:0000269|PubMed:12525602}. Note=Found
in perinuclear cytoplasmic viral factories during assembly. In the
virion, located in the core shell, which functions like a matrix
between the DNA-containing nucleoid and the inner envelope.
-!- SUBCELLULAR LOCATION: p14: Virion {ECO:0000305}. Host cytoplasm,
host perinuclear region. Note=Found in perinuclear cytoplasmic
viral factories during assembly. In the virion, located in the
core shell, which functions like a matrix between the DNA-
containing nucleoid and the inner envelope.
-!- SUBCELLULAR LOCATION: p37: Virion {ECO:0000305}. Host cytoplasm,
host perinuclear region {ECO:0000269|PubMed:17580096}. Host
nucleus {ECO:0000269|PubMed:17580096}. Note=Nuclear at early
stages of infection. Found in perinuclear cytoplasmic viral
factories during assembly. In the virion, located in the core
shell, which functions like a matrix between the DNA-containing
nucleoid and the inner envelope.
-!- SUBCELLULAR LOCATION: p150: Virion {ECO:0000305}. Host cytoplasm,
host perinuclear region {ECO:0000269|PubMed:12525602}. Note=Found
in perinuclear cytoplasmic viral factories during assembly. In the
virion, located in the core shell, which functions like a matrix
between the DNA-containing nucleoid and the inner envelope.
-!- INDUCTION: Expressed late in the infection.
-!- PTM: The polyprotein is not glycosylated.
-!- PTM: Specific enzymatic cleavages in vivo yield mature proteins.
{ECO:0000269|PubMed:8335009}.
-!- SIMILARITY: Belongs to the asfivirus polyprotein pp220 family.
{ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=CAA61203.1; Type=Frameshift; Positions=713; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; Z22777; CAA80455.1; -; Genomic_DNA.
EMBL; U18466; AAA65321.1; -; Genomic_DNA.
EMBL; X87965; CAA61203.1; ALT_FRAME; Genomic_DNA.
PIR; S35307; S35307.
RefSeq; NP_042785.1; NC_001659.2.
ELM; Q08358; -.
iPTMnet; Q08358; -.
GeneID; 22220321; -.
KEGG; vg:22220321; -.
OrthoDB; VOG090000YJ; -.
Proteomes; UP000000624; Genome.
GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO; GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell.
1: Evidence at protein level;
Coiled coil; Complete proteome; Host cytoplasm; Host nucleus;
Late protein; Lipoprotein; Myristate; Reference proteome; Virion.
INIT_MET 1 1 Removed; by host.
PROPEP 2 45
/FTId=PRO_0000036722.
CHAIN 46 894 Polyprotein pp220. {ECO:0000255}.
/FTId=PRO_0000355531.
CHAIN 46 369 p34. {ECO:0000255}.
/FTId=PRO_0000036723.
CHAIN 370 523 p14. {ECO:0000255}.
/FTId=PRO_0000036724.
CHAIN 524 894 p37. {ECO:0000255}.
/FTId=PRO_0000036725.
CHAIN 895 2475 p150. {ECO:0000255}.
/FTId=PRO_0000036726.
COILED 2185 2212 {ECO:0000255}.
COMPBIAS 551 554 Poly-Tyr.
SITE 45 46 Cleavage; by viral protease S273R.
{ECO:0000255}.
SITE 369 370 Cleavage; by viral protease S273R.
{ECO:0000255}.
SITE 523 524 Cleavage; by viral protease S273R.
{ECO:0000255}.
SITE 894 895 Cleavage; by viral protease S273R.
{ECO:0000255}.
LIPID 2 2 N-myristoyl glycine; by host.
{ECO:0000269|PubMed:8335009}.
SEQUENCE 2475 AA; 281482 MW; 5D0415A506BE218E CRC64;
MGNRGSSTSS RPPLSSEANL YAKLQDHIQR QTRPFSGGGY FNGGGDKNPV QHIKDYHIDS
VSSKAKLRVI EGIIRAIAKI GFKVDTKQPI EDILKDIKKQ LPDPRAGSTF VKNAEKQETV
CKMIADAINQ EFIDLGQDKL IDTTDGAASI CRQIVLYINS LTHGLRAEYL DVHGSIENTL
ENIKLLNDAI KQLHERMVTE VTKAAPNEEV INAVTMIEAV YRRLLNEQNL QINILTNFID
NILTPTQKEL DKLQTDEVDI IKLLNDTNSV LGTKNFGKVL SYTLCNLGIA ASVANKINKA
LQKVGLKVEQ YLQSKNWAEF DKELDLKRFS GLVSAENIAE FEKAVNLLRQ TFNERHKILE
NSCAKKGGDE EKTPLDRRIE AQRLDRKHIL MEFLNKSTQA YNDFLENVKK IGIKLVKEIA
LTPNITRLRD ALSRINDMGT IALDLSLIGF YTNAAAREER ETFLTQFMLV KNVLEEQSKI
DPNFKNLYDS CSRLLQIIDF YTDIVQKKYG GGEDCECTRV GGAALTVEEL GLSKAARSQV
DLNQAINTFM YYYYVAQIYS NLTHNKQEFQ SYEENYATIL GDAIAGRLMQ LDTEKNARIN
SPAVDLARGH VGPNPGGAQE ADWKAAVSAI ELEYDVKRRF YRALEGLDLY LKNITKTFVN
NIDSIQTVQQ MLDGVRIIGR WFTEATGDTL AQVFESFPTS AGNDSNVFTD NAPAGHYYEK
VAAEIQQGRS VGTLRPVRAS QAKNIRDLIG RSLSNFQALK NIINAFARIG DMLGGEELRQ
MVPMSPLQIY KTLLEYIQHS ALSVGLKNLN QSEIGGQRVA LARTPEEAAQ RVYLSTVRVN
DALSTRWETE DVFFTFMLKS MAAKIFIVLG IYDMFERPEP VYKLIPTRMI LGGADELEPE
VIPEAAELYF RLPRLAEFYQ KLFSFRDENV QISMLPELEG IFSGLIRIIF MRPIELINIG
DYSETEIRQL IKEINVIYQH FNLEYGEQEA TKKALIHFVN EINRRFGVIT RTEWEKFQRI
VQEARTMNDF GMMNQTNYSI LPDEDGYTQS SQLLPSDRFI SPSTQPTPKW RPALYNIDSV
DVQTGMLQPN SQWDLVQKFR KQLSEMFEDP SLQQELGKVS YQELIRQAIN ELKKEHTDKI
QIVSKLIQGS ESLADTDVNK IFLFHETVIT GLNLLSAIYV LLNNFRNNIK GLDLDTIQKS
IIEWLRETQA ANVNRANLID WLGRKHGAIS EIRNPGLVVK ENDVRLSRVY PDPTTNATAP
QDQNLVTETL FAWIVPYVGI PAGGGVRAEQ ELAARYLVDN QRIMQLLLTN IFEMTSSFNK
MVQVRFPETS TAQVHLDFTG LISLIDSLMA DTKYFLNLLR PHIDKNIIQY YENRSNPGSF
YWLEEHLIDK LIKPPTDAGG RPLPGGELGL EGVNQIINKT YILLTKPYNV LQLRGGVQRR
DAANIQINNN PQPSERFEQY GRVFSRLVFY DALENNSGLR VEQVVLGDFR LSNLIRTNNA
QEENTLSYWD NMAPRTYANV NDAANNLRRY RLYGSDYGIQ NNRSMMMVFN QLVASYIARF
YDAPSGKIYL NLINAFANGN FSQAVMELGY THPDLARDNI AFGHRGDPTE QSVLLLSLGL
MLQRLIKDTN RQGLSQHLIS TLTEIPIYLK ENYRANLPLF NKMFNILISQ GELLKQFIQY
TNVQLARPNL MGLLGANNDS VIYYNNNINV PMTGLSVGQA ALRGIGGVFR PNVTLMPLGD
AQNNTSDVVR KRLVAVIDGI IRGSHTLADS AMEVLHELTD HPIYLETEEH FIQNYMSRYN
KEPLMPFSLS LYYLRDLRIE NNEVYDPLLY PNLESGSPEF KLLYGTRKLL GNDPVQLSDM
PGVQLIMKNY NETVVAREQI TPTRFEHFYT HAIQALRFIV NIRSFKTVMM YNENTFGGVN
LISENRDDKP IITAGIGMNA VYSLRKTLQD VISFVESSYQ EEQINHIHKI VSPKGQTRTL
GSNRERERIF NLFDMNIIPI NVNALMRSIP LANIYNYDYS FEEIACLMYG ISAEKVRSLN
TAAPQPDIAE VLNIPNRPPM NTREFMLKLL INPYVSVSIT QYGNELMSKG SAGYMSRIFR
GDNALNMGRP KFLSDQIFNK VLFGSLYPTQ FDYDEAGPGL AAGIQRGREQ WGQPLSEYIN
QALHELVRTI RIPQKLRVLR NIIVKNQLIA DLTTIREQLV SMRREVENMI QTPEIQNNPT
PEVIAAAQNW TQQYRARVDT LINFIGNIGQ PNSMLDLIQT ITPVTVRAQL GVIFNRHGIP
VPHPRQILQT DDEATQWFMT NILNIPAIIM TPFTDLANDL RTFLETLERY VFNVPRWLGP
STGRVARAPV RMAPRDMRHP ISYTENSVLT YITEQNREEG PWSIVKQVGV GIQKPTLVQI
GKDRFDTRLI RNLIFITNIQ RLLRLRLNLE LSQFRNVLVS PDHIINPSIT EYGFSITGPS
ETFSDKQYDS DIRIL


Related products :

Catalog number Product name Quantity
60B395 Polyclonal Antibodies: polyprotein-(N-terminal); Specificity: polyprotein-(N-terminal) ; Application: IHC 0.1mg
60B399a Polyclonal Antibodies: polyprotein-(C-terminal); Specificity: polyprotein-(C-terminal) ; Application: IHC 0.1mg
EIAAB12585 Endogenous retrovirus group FRD member 1,Envelope polyprotein,ERVFRD-1,ERVFRDE1,HERV-FRD,HERV-FRD_6p24.1 provirus ancestral Env polyprotein,Homo sapiens,Human,Syncytin-2,UNQ6191_PRO20218
EIAAB12959 Envelope polyprotein,ERVK5,HERV-K(II) envelope protein,HERV-K_3q12.3 provirus ancestral Env polyprotein,Homo sapiens,Human
orb100888 FMDV Polyprotein antibody Polyclonal Rabbit Polyclonal to FMDV Polyprotein. 100
orb102611 FMDV Polyprotein antibody Polyclonal Rabbit Polyclonal to FMDV Polyprotein. 100
EIAAB13041 Endogenous retrovirus group W member 1,Envelope polyprotein gPr73,Enverin,Env-W,ERVW-1,ERVWE1,HERV-7q Envelope protein,HERV-W envelope protein,HERV-W_7q21.2 provirus ancestral Env polyprotein,Homo sap
EIAAB12958 Envelope polyprotein,EnvK2 protein,ERVK6,HERV-K(C7) envelope protein,HERV-K(HML-2.HOM) envelope protein,HERV-K_7p22.1 provirus ancestral Env polyprotein,HERV-K108 envelope protein,Homo sapiens,Human
AB5HCore P1 Polyclonal Antibodies: Anti-HCV Core Polyprotein(Very N-terminal) Polyclonal Antibody ; Specificity: Anti-HCV Core Polyprotein(Very N-terminal) Polyclonal Antibody ; Application: IHC 0.1mg
AB5HCore P2 Polyclonal Antibodies: Anti-HCV Core Polyprotein(N-terminal) Polyclonal Antibody ; Specificity: Anti-HCV Core Polyprotein(N-terminal) Polyclonal Antibody ; Application: IHC 0.1mg
AB1I144 Polyclonal Antibodies: Anti-CrPV Genome polyprotein Polyclonal Antibody; Specificity: Anti-CrPV Genome polyprotein Polyclonal Antibody ; Application: IHC 0.1mg
000773A Gag Polyprotein 250ul
XW-8151 Gag polyprotein Antibody 0.05 mg
10-663-45443 HIV-I Antigen (HIV-I ) - Env polyprotein N_A 0.5 mg
10-663-45451 HIV-1 gp41 - Env polyprotein N_A 1 mg
10-663-45443 HIV-I Antigen (HIV-I ) - Env polyprotein N_A 0.1 mg
10-663-45443 HIV-I Antigen (HIV-I ) - Env polyprotein N_A 1 mg
10-663-45451 HIV-1 gp41 - Env polyprotein N_A 0.1 mg
10-663-45451 HIV-1 gp41 - Env polyprotein N_A 0.5 mg
DP1003P HCV chimeric polyprotein 1 mg
DP1002P HCV chimeric polyprotein 1 mg
A020239 Rabbit Anti-AEV polyprotein Ab 200Ul
15-288-10807F Gag polyprotein - Pr55Gag Polyclonal 0.1 mg
H-1232 HIV-1 gag Polyprotein (121-140) 98 percent C86H138N26O34 CAS: 5mg
10-663-45454 HIV-1 gp41 aa 32kDa - Env polyprotein N_A 0.1 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur