Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Polyubiquitin-B [Cleaved into: Ubiquitin]

 UBB_BOVIN               Reviewed;         305 AA.
P0CG53; O97577; P02248; P02249; P02250; P62990; P80169; Q01235;
Q24K23; Q28169; Q28170; Q29120; Q3T0V5; Q3ZCE3; Q862C1; Q862F4;
Q862M4; Q862T5; Q862X8; Q91887; Q91888;
10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
10-AUG-2010, sequence version 1.
05-DEC-2018, entry version 76.
RecName: Full=Polyubiquitin-B;
RecName: Full=Ubiquitin;
Flags: Precursor;
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
TISSUE=Seminal vesicle;
PubMed=8382528; DOI=10.1016/0167-4781(93)90297-Q;
Wempe F., Scheit K.H.;
"Characterization of a full-length cDNA encoding a bovine four tandem-
repeat ubiquitin.";
Biochim. Biophys. Acta 1172:209-211(1993).
PubMed=12658628; DOI=10.1002/mrd.10292;
Ishiwata H., Katsuma S., Kizaki K., Patel O.V., Nakano H.,
Takahashi T., Imai K., Hirasawa A., Shiojima S., Ikawa H., Suzuki Y.,
Tsujimoto G., Izaike Y., Todoroki J., Hashizume K.;
"Characterization of gene expression profiles in early bovine
pregnancy using a custom cDNA microarray.";
Mol. Reprod. Dev. 65:9-18(2003).
STRAIN=Crossbred X Angus; TISSUE=Ileum, and Liver;
NIH - Mammalian Gene Collection (MGC) project;
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
PubMed=1170880; DOI=10.1021/bi00681a026;
Schlesinger D.H., Goldstein G., Niall H.D.;
"The complete amino acid sequence of ubiquitin, an adenylate cyclase
stimulating polypeptide probably universal in living cells.";
Biochemistry 14:2214-2218(1975).
PubMed=6254502; DOI=10.1016/0006-291X(80)91188-2;
Hamilton J.W., Rouse J.B.;
"The biosynthesis of ubiquitin by parathyroid gland.";
Biochem. Biophys. Res. Commun. 96:114-120(1980).
PubMed=1333954; DOI=10.1111/j.1432-1033.1992.tb17446.x;
Zdebska E., Antoniewicz J., Nilsson B., Sandhoff K., Fuerst W.,
Janik P., Koscielak J.;
"Ganglioside binding proteins of calf brain with ubiquitin-like N-
Eur. J. Biochem. 210:483-489(1992).
PubMed=1846490; DOI=10.1016/0042-6822(91)90074-L;
Meyers G., Tautz N., Dubovi E.J., Thiel H.-J.;
"Viral cytopathogenicity correlated with integration of ubiquitin-
coding sequences.";
Virology 180:602-616(1991).
-!- FUNCTION: Ubiquitin: Exists either covalently attached to another
protein, or free (unanchored). When covalently bound, it is
conjugated to target proteins via an isopeptide bond either as a
monomer (monoubiquitin), a polymer linked via different Lys
residues of the ubiquitin (polyubiquitin chains) or a linear
polymer linked via the initiator Met of the ubiquitin (linear
polyubiquitin chains). Polyubiquitin chains, when attached to a
target protein, have different functions depending on the Lys
residue of the ubiquitin that is linked: Lys-6-linked may be
involved in DNA repair; Lys-11-linked is involved in ERAD
(endoplasmic reticulum-associated degradation) and in cell-cycle
regulation; Lys-29-linked is involved in lysosomal degradation;
Lys-33-linked is involved in kinase modification; Lys-48-linked is
involved in protein degradation via the proteasome; Lys-63-linked
is involved in endocytosis, DNA-damage responses as well as in
signaling processes leading to activation of the transcription
factor NF-kappa-B. Linear polymer chains formed via attachment by
the initiator Met lead to cell signaling. Ubiquitin is usually
conjugated to Lys residues of target proteins, however, in rare
cases, conjugation to Cys or Ser residues has been observed. When
polyubiquitin is free (unanchored-polyubiquitin), it also has
distinct roles, such as in activation of protein kinases, and in
signaling. {ECO:0000250|UniProtKB:P0CG47}.
O14964:HGS (xeno); NbExp=7; IntAct=EBI-5333021, EBI-740220;
P38753:HSE1 (xeno); NbExp=2; IntAct=EBI-5333021, EBI-1382;
Q92783:STAM (xeno); NbExp=9; IntAct=EBI-5333021, EBI-752333;
P40343:VPS27 (xeno); NbExp=6; IntAct=EBI-5333021, EBI-20380;
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus
-!- PTM: Ubiquitin: Phosphorylated at Ser-65 by PINK1 during
mitophagy. Phosphorylated ubiquitin specifically binds and
activates parkin (PRKN), triggering mitophagy. Phosphorylation
does not affect E1-mediated E2 charging of ubiquitin but affects
discharging of E2 enzymes to form polyubiquitin chains. It also
affects deubiquitination by deubiquitinase enzymes such as USP30.
-!- PTM: Ubiquitin: Mono-ADP-riblosylated at the C-terminus by PARP9,
a component of the PPAR9-DTX3L complex. ADP-ribosylation requires
processing by E1 and E2 enzymes and prevents ubiquitin conjugation
to substrates such as histones. {ECO:0000250|UniProtKB:P0CG47}.
-!- MISCELLANEOUS: Ubiquitin is encoded by 4 different genes. Uba52
and Rps27a genes code for a single copy of ubiquitin fused to the
ribosomal proteins L40 and S27a, respectively. UBB and UBC genes
code for a polyubiquitin precursor with exact head to tail
repeats, the number of repeats differ between species and strains.
-!- MISCELLANEOUS: For the sake of clarity sequence features are
annotated only for the first chain, and are not repeated for each
of the following chains.
-!- SIMILARITY: Belongs to the ubiquitin family. {ECO:0000305}.
Sequence=BAC56573.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Sequence=BAC56573.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the C-terminal part.; Evidence={ECO:0000305};
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
EMBL; Z18245; CAA79146.1; -; mRNA.
EMBL; AB099044; BAC56534.1; -; mRNA.
EMBL; AB099083; BAC56573.1; ALT_SEQ; mRNA.
EMBL; BC114001; AAI14002.1; -; mRNA.
EMBL; M62429; AAA30720.1; -; mRNA.
PIR; I45964; I45964.
PIR; S29853; S29853.
RefSeq; NP_776558.1; NM_174133.2.
UniGene; Bt.111403; -.
UniGene; Bt.2878; -.
PDB; 5TR4; X-ray; 2.20 A; B/D=1-76.
PDBsum; 5TR4; -.
ProteinModelPortal; P0CG53; -.
SMR; P0CG53; -.
BioGrid; 158705; 2.
IntAct; P0CG53; 10.
MINT; P0CG53; -.
STRING; 9913.ENSBTAP00000022919; -.
PaxDb; P0CG53; -.
PeptideAtlas; P0CG53; -.
PRIDE; P0CG53; -.
Ensembl; ENSBTAT00000022919; ENSBTAP00000022919; ENSBTAG00000017246.
GeneID; 281370; -.
KEGG; bta:281370; -.
CTD; 7314; -.
eggNOG; KOG0001; Eukaryota.
eggNOG; COG5272; LUCA.
GeneTree; ENSGT00940000162439; -.
InParanoid; P0CG53; -.
KO; K04551; -.
OrthoDB; EOG091G178I; -.
TreeFam; TF300820; -.
Reactome; R-BTA-110312; Translesion synthesis by REV1.
Reactome; R-BTA-110314; Recognition of DNA damage by PCNA-containing replication complex.
Reactome; R-BTA-110320; Translesion Synthesis by POLH.
Reactome; R-BTA-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
Reactome; R-BTA-1253288; Downregulation of ERBB4 signaling.
Reactome; R-BTA-1295596; Spry regulation of FGF signaling.
Reactome; R-BTA-1358803; Downregulation of ERBB2:ERBB3 signaling.
Reactome; R-BTA-168638; NOD1/2 Signaling Pathway.
Reactome; R-BTA-174048; APC/C:Cdc20 mediated degradation of Cyclin B.
Reactome; R-BTA-174084; Autodegradation of Cdh1 by Cdh1:APC/C.
Reactome; R-BTA-174154; APC/C:Cdc20 mediated degradation of Securin.
Reactome; R-BTA-174178; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1.
Reactome; R-BTA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
Reactome; R-BTA-179409; APC-Cdc20 mediated degradation of Nek2A.
Reactome; R-BTA-182971; EGFR downregulation.
Reactome; R-BTA-187577; SCF(Skp2)-mediated degradation of p27/p21.
Reactome; R-BTA-195253; Degradation of beta-catenin by the destruction complex.
Reactome; R-BTA-201681; TCF dependent signaling in response to WNT.
Reactome; R-BTA-205043; NRIF signals cell death from the nucleus.
Reactome; R-BTA-209543; p75NTR recruits signalling complexes.
Reactome; R-BTA-209560; NF-kB is activated and signals survival.
Reactome; R-BTA-2122948; Activated NOTCH1 Transmits Signal to the Nucleus.
Reactome; R-BTA-2173788; Downregulation of TGF-beta receptor signaling.
Reactome; R-BTA-2173791; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition).
Reactome; R-BTA-2173795; Downregulation of SMAD2/3:SMAD4 transcriptional activity.
Reactome; R-BTA-2173796; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription.
Reactome; R-BTA-2467813; Separation of Sister Chromatids.
Reactome; R-BTA-2559580; Oxidative Stress Induced Senescence.
Reactome; R-BTA-2559582; Senescence-Associated Secretory Phenotype (SASP).
Reactome; R-BTA-2559585; Oncogene Induced Senescence.
Reactome; R-BTA-2672351; Stimuli-sensing channels.
Reactome; R-BTA-3134975; Regulation of innate immune responses to cytosolic DNA.
Reactome; R-BTA-3322077; Glycogen synthesis.
Reactome; R-BTA-349425; Autodegradation of the E3 ubiquitin ligase COP1.
Reactome; R-BTA-3769402; Deactivation of the beta-catenin transactivating complex.
Reactome; R-BTA-382556; ABC-family proteins mediated transport.
Reactome; R-BTA-445989; TAK1 activates NFkB by phosphorylation and activation of IKKs complex.
Reactome; R-BTA-450302; activated TAK1 mediates p38 MAPK activation.
Reactome; R-BTA-450321; JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1.
Reactome; R-BTA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA.
Reactome; R-BTA-4608870; Asymmetric localization of PCP proteins.
Reactome; R-BTA-4641257; Degradation of AXIN.
Reactome; R-BTA-4641258; Degradation of DVL.
Reactome; R-BTA-4641263; Regulation of FZD by ubiquitination.
Reactome; R-BTA-5205685; Pink/Parkin Mediated Mitophagy.
Reactome; R-BTA-532668; N-glycan trimming in the ER and Calnexin/Calreticulin cycle.
Reactome; R-BTA-5357905; Regulation of TNFR1 signaling.
Reactome; R-BTA-5357956; TNFR1-induced NFkappaB signaling pathway.
Reactome; R-BTA-5358346; Hedgehog ligand biogenesis.
Reactome; R-BTA-5607761; Dectin-1 mediated noncanonical NF-kB signaling.
Reactome; R-BTA-5610780; Degradation of GLI1 by the proteasome.
Reactome; R-BTA-5610785; GLI3 is processed to GLI3R by the proteasome.
Reactome; R-BTA-5632684; Hedgehog 'on' state.
Reactome; R-BTA-5654726; Negative regulation of FGFR1 signaling.
Reactome; R-BTA-5654727; Negative regulation of FGFR2 signaling.
Reactome; R-BTA-5654732; Negative regulation of FGFR3 signaling.
Reactome; R-BTA-5654733; Negative regulation of FGFR4 signaling.
Reactome; R-BTA-5655862; Translesion synthesis by POLK.
Reactome; R-BTA-5656121; Translesion synthesis by POLI.
Reactome; R-BTA-5656169; Termination of translesion DNA synthesis.
Reactome; R-BTA-5658442; Regulation of RAS by GAPs.
Reactome; R-BTA-5668541; TNFR2 non-canonical NF-kB pathway.
Reactome; R-BTA-5675221; Negative regulation of MAPK pathway.
Reactome; R-BTA-5675482; Regulation of necroptotic cell death.
Reactome; R-BTA-5676590; NIK-->noncanonical NF-kB signaling.
Reactome; R-BTA-5684264; MAP3K8 (TPL2)-dependent MAPK1/3 activation.
Reactome; R-BTA-5685942; HDR through Homologous Recombination (HRR).
Reactome; R-BTA-5687128; MAPK6/MAPK4 signaling.
Reactome; R-BTA-5689603; UCH proteinases.
Reactome; R-BTA-5689877; Josephin domain DUBs.
Reactome; R-BTA-5689880; Ub-specific processing proteases.
Reactome; R-BTA-5689896; Ovarian tumor domain proteases.
Reactome; R-BTA-5689901; Metalloprotease DUBs.
Reactome; R-BTA-5693565; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks.
Reactome; R-BTA-5696394; DNA Damage Recognition in GG-NER.
Reactome; R-BTA-5696395; Formation of Incision Complex in GG-NER.
Reactome; R-BTA-5696397; Gap-filling DNA repair synthesis and ligation in GG-NER.
Reactome; R-BTA-5696400; Dual Incision in GG-NER.
Reactome; R-BTA-6781823; Formation of TC-NER Pre-Incision Complex.
Reactome; R-BTA-6782135; Dual incision in TC-NER.
Reactome; R-BTA-6782210; Gap-filling DNA repair synthesis and ligation in TC-NER.
Reactome; R-BTA-6783310; Fanconi Anemia Pathway.
Reactome; R-BTA-6804756; Regulation of TP53 Activity through Phosphorylation.
Reactome; R-BTA-6804757; Regulation of TP53 Degradation.
Reactome; R-BTA-6804760; Regulation of TP53 Activity through Methylation.
Reactome; R-BTA-6807004; Negative regulation of MET activity.
Reactome; R-BTA-68827; CDT1 association with the CDC6:ORC:origin complex.
Reactome; R-BTA-68949; Orc1 removal from chromatin.
Reactome; R-BTA-69017; CDK-mediated phosphorylation and removal of Cdc6.
Reactome; R-BTA-69229; Ubiquitin-dependent degradation of Cyclin D1.
Reactome; R-BTA-69231; Cyclin D associated events in G1.
Reactome; R-BTA-69481; G2/M Checkpoints.
Reactome; R-BTA-69541; Stabilization of p53.
Reactome; R-BTA-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
Reactome; R-BTA-8849469; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1.
Reactome; R-BTA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint.
Reactome; R-BTA-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis.
Reactome; R-BTA-8856825; Cargo recognition for clathrin-mediated endocytosis.
Reactome; R-BTA-8856828; Clathrin-mediated endocytosis.
Reactome; R-BTA-8863795; Downregulation of ERBB2 signaling.
Reactome; R-BTA-8866652; Synthesis of active ubiquitin: roles of E1 and E2 enzymes.
Reactome; R-BTA-8866654; E3 ubiquitin ligases ubiquitinate target proteins.
Reactome; R-BTA-8939236; RUNX1 regulates transcription of genes involved in differentiation of HSCs.
Reactome; R-BTA-8939902; Regulation of RUNX2 expression and activity.
Reactome; R-BTA-8941858; Regulation of RUNX3 expression and activity.
Reactome; R-BTA-8948747; Regulation of PTEN localization.
Reactome; R-BTA-8948751; Regulation of PTEN stability and activity.
Reactome; R-BTA-8951664; Neddylation.
Reactome; R-BTA-901032; ER Quality Control Compartment (ERQC).
Reactome; R-BTA-9010553; Regulation of expression of SLITs and ROBOs.
Reactome; R-BTA-9013507; NOTCH3 Activation and Transmission of Signal to the Nucleus.
Reactome; R-BTA-9020702; Interleukin-1 signaling.
Reactome; R-BTA-9033241; Peroxisomal protein import.
Reactome; R-BTA-912631; Regulation of signaling by CBL.
Reactome; R-BTA-917729; Endosomal Sorting Complex Required For Transport (ESCRT).
Reactome; R-BTA-917937; Iron uptake and transport.
Reactome; R-BTA-936440; Negative regulators of DDX58/IFIH1 signaling.
Reactome; R-BTA-936964; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon.
Reactome; R-BTA-937041; IKK complex recruitment mediated by RIP1.
Reactome; R-BTA-937042; IRAK2 mediated activation of TAK1 complex.
Reactome; R-BTA-937072; TRAF6-mediated induction of TAK1 complex within TLR4 complex.
Reactome; R-BTA-975163; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation.
Reactome; R-BTA-983168; Antigen processing: Ubiquitination & Proteasome degradation.
Proteomes; UP000009136; Chromosome 19.
Bgee; ENSBTAG00000017246; Expressed in 9 organ(s), highest expression level in testis.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
GO; GO:0043209; C:myelin sheath; IEA:Ensembl.
GO; GO:0043005; C:neuron projection; IEA:Ensembl.
GO; GO:0043025; C:neuronal cell body; IEA:Ensembl.
GO; GO:0005634; C:nucleus; IBA:GO_Central.
GO; GO:0031386; F:protein tag; IBA:GO_Central.
GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
GO; GO:0097009; P:energy homeostasis; IEA:Ensembl.
GO; GO:0060613; P:fat pad development; IEA:Ensembl.
GO; GO:0008585; P:female gonad development; IEA:Ensembl.
GO; GO:0007144; P:female meiosis I; IEA:Ensembl.
GO; GO:0021888; P:hypothalamus gonadotrophin-releasing hormone neuron development; IEA:Ensembl.
GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
GO; GO:0047497; P:mitochondrion transport along microtubule; IEA:Ensembl.
GO; GO:0019941; P:modification-dependent protein catabolic process; IBA:GO_Central.
GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
GO; GO:1902255; P:positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
GO; GO:1902527; P:positive regulation of protein monoubiquitination; IEA:Ensembl.
GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
GO; GO:1901214; P:regulation of neuron death; IEA:Ensembl.
GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IEA:Ensembl.
GO; GO:0072520; P:seminiferous tubule development; IEA:Ensembl.
InterPro; IPR019956; Ubiquitin.
InterPro; IPR029071; Ubiquitin-like_domsf.
InterPro; IPR019954; Ubiquitin_CS.
InterPro; IPR000626; Ubiquitin_dom.
Pfam; PF00240; ubiquitin; 4.
SMART; SM00213; UBQ; 4.
SUPFAM; SSF54236; SSF54236; 4.
1: Evidence at protein level;
3D-structure; ADP-ribosylation; Complete proteome; Cytoplasm;
Direct protein sequencing; Isopeptide bond; Nucleus; Phosphoprotein;
Reference proteome; Repeat; Ubl conjugation.
CHAIN 1 76 Ubiquitin.
CHAIN 77 152 Ubiquitin.
CHAIN 153 228 Ubiquitin.
CHAIN 229 304 Ubiquitin.
PROPEP 305 305
DOMAIN 1 76 Ubiquitin-like 1. {ECO:0000255|PROSITE-
DOMAIN 77 152 Ubiquitin-like 2. {ECO:0000255|PROSITE-
DOMAIN 153 228 Ubiquitin-like 3. {ECO:0000255|PROSITE-
DOMAIN 229 304 Ubiquitin-like 4. {ECO:0000255|PROSITE-
BINDING 54 54 Activating enzyme.
BINDING 72 72 Activating enzyme.
SITE 68 68 Essential for function.
MOD_RES 65 65 Phosphoserine; by PINK1.
MOD_RES 141 141 Phosphoserine.
CROSSLNK 48 48 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in ubiquitin).
CROSSLNK 76 76 Glycyl lysine isopeptide (Gly-Lys)
(interchain with K-? in acceptor
CROSSLNK 82 82 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in ubiquitin).
CROSSLNK 87 87 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in ubiquitin).
CROSSLNK 103 103 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in ubiquitin).
CROSSLNK 105 105 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in ubiquitin).
CROSSLNK 124 124 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in ubiquitin).
CROSSLNK 139 139 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in ubiquitin).
CONFLICT 133 133 S -> F (in Ref. 1; CAA79146).
STRAND 230 235 {ECO:0000244|PDB:5TR4}.
STRAND 240 244 {ECO:0000244|PDB:5TR4}.
HELIX 251 262 {ECO:0000244|PDB:5TR4}.
HELIX 266 268 {ECO:0000244|PDB:5TR4}.
STRAND 270 273 {ECO:0000244|PDB:5TR4}.
STRAND 275 277 {ECO:0000244|PDB:5TR4}.
HELIX 285 287 {ECO:0000244|PDB:5TR4}.
STRAND 294 298 {ECO:0000244|PDB:5TR4}.
SEQUENCE 305 AA; 34308 MW; 1E6C7878AE958E68 CRC64;

Related products :

Catalog number Product name Quantity
25-863 RNF217 is an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. 0.05 mg
25-847 MARCH7 is an E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioeste 0.05 mg
29-847 KIAA1333 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted subs 0.05 mg
25-866 HECTD2 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substr 0.05 mg
EIAAB45098 Deubiquitinating enzyme 8,Kiaa0055,Mouse,mUBPy,Mus musculus,Ubiquitin carboxyl-terminal hydrolase 8,Ubiquitin isopeptidase Y,Ubiquitin thiolesterase 8,Ubiquitin-specific-processing protease 8,Ubpy,Usp
EIAAB45002 41 kDa ubiquitin-specific protease,Deubiquitinating enzyme 2,Rat,Rattus norvegicus,Ubiquitin carboxyl-terminal hydrolase 2,Ubiquitin thiolesterase 2,Ubiquitin-specific-processing protease 2,Ubiquitin-
EIAAB45097 Deubiquitinating enzyme 8,Homo sapiens,hUBPy,Human,KIAA0055,Ubiquitin carboxyl-terminal hydrolase 8,Ubiquitin isopeptidase Y,Ubiquitin thiolesterase 8,Ubiquitin-specific-processing protease 8,UBPY,USP
EIAAB44865 Pig,Polyubiquitin-C,Sus scrofa,UBC
RT30_MOUSE Rat ELISA Kit FOR Polyubiquitin-C 96T
EH737 Polyubiquitin-B Elisa Kit 96T
E0434h Rat ELISA Kit FOR Polyubiquitin-C 96T
EIAAB45096 Deubiquitinating enzyme 7,HAUSP,Herpesvirus-associated ubiquitin-specific protease,Homo sapiens,Human,Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin thioesterase 7,Ubiquitin-specific-processing pro
EIAAB45023 Deubiquitinating enzyme 27,Mouse,Mus musculus,Ubiquitin carboxyl-terminal hydrolase 27,Ubiquitin thiolesterase 27,Ubiquitin-specific-processing protease 27,Usp27,Usp27x,X-linked ubiquitin carboxyl-ter
EIAAB44981 Deubiquitinating enzyme 12,Mouse,Mus musculus,Ubh1,Ubiquitin carboxyl-terminal hydrolase 12,Ubiquitin thiolesterase 12,Ubiquitin-hydrolyzing enzyme 1,Ubiquitin-specific-processing protease 12,Usp12
EIAAB45095 Deubiquitinating enzyme 7,Hausp,Herpesvirus-associated ubiquitin-specific protease,mHAUSP,Mouse,Mus musculus,Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin thioesterase 7,Ubiquitin-specific-process
EIAAB45094 Deubiquitinating enzyme 7,Hausp,Herpesvirus-associated ubiquitin-specific protease,Rat,Rattus norvegicus,rHAUSP,Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin thioesterase 7,Ubiquitin-specific-proc
EIAAB44983 Deubiquitinating enzyme 12,Homo sapiens,Human,UBH1,Ubiquitin carboxyl-terminal hydrolase 12,Ubiquitin thiolesterase 12,Ubiquitin-hydrolyzing enzyme 1,Ubiquitin-specific-processing protease 12,USP12,US
CH55 Recombinant Human Polyubiquitin-B 50 ug
EIAAB44866 Polyubiquitin-C,Rat,Rattus norvegicus,Ubc
CNIH2_RAT Human ELISA Kit FOR Polyubiquitin-C 96T
E1143m Mouse ELISA Kit FOR Polyubiquitin-C 96T
EIAAB44867 Mouse,Mus musculus,Polyubiquitin-C,Ubc
E0298h Human ELISA Kit FOR Polyubiquitin-C 96T
NRX1B_HUMAN Human ELISA Kit FOR Polyubiquitin-C 96T
CH55 Recombinant Human Polyubiquitin-B 1 mg


GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur

Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur



9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123

GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U

spain@gentaur.com | Gentaur | Gentaur

ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636

GENTAUR Poland Sp. z o.o.

ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556


Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur