Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Probable manganese-transporting ATPase PDR2 (EC 3.6.3.-) (Protein MALE GAMETOGENESIS IMPAIRED ANTHERS) (Protein PHOSPHATE DEFICIENCY RESPONSE 2)

 PDR2_ARATH              Reviewed;        1179 AA.
Q9LT02;
11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
22-NOV-2017, entry version 125.
RecName: Full=Probable manganese-transporting ATPase PDR2;
EC=3.6.3.-;
AltName: Full=Protein MALE GAMETOGENESIS IMPAIRED ANTHERS;
AltName: Full=Protein PHOSPHATE DEFICIENCY RESPONSE 2;
Name=PDR2; Synonyms=MIA; OrderedLocusNames=At5g23630;
ORFNames=MQM1.11;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=10718197; DOI=10.1093/dnares/7.1.31;
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
features of the regions of 3,076,755 bp covered by sixty P1 and TAC
clones.";
DNA Res. 7:31-63(2000).
[2]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
The Arabidopsis Information Portal (Araport);
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 702-1179.
STRAIN=cv. Columbia;
PubMed=14993207; DOI=10.1101/gr.1515604;
Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G.,
Caboche M., Weissenbach J., Salanoubat M.;
"Whole genome sequence comparisons and 'full-length' cDNA sequences: a
combined approach to evaluate and improve Arabidopsis genome
annotation.";
Genome Res. 14:406-413(2004).
[4]
FUNCTION, AND DISRUPTION PHENOTYPE.
PubMed=14996215; DOI=10.1111/j.1365-313X.2004.02005.x;
Ticconi C.A., Delatorre C.A., Lahner B., Salt D.E., Abel S.;
"Arabidopsis pdr2 reveals a phosphate-sensitive checkpoint in root
development.";
Plant J. 37:801-814(2004).
[5]
FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
PubMed=16291648; DOI=10.1101/gad.357305;
Jakobsen M.K., Poulsen L.R., Schulz A., Fleurat-Lessard P., Moller A.,
Husted S., Schiott M., Amtmann A., Palmgren M.G.;
"Pollen development and fertilization in Arabidopsis is dependent on
the MALE GAMETOGENESIS IMPAIRED ANTHERS gene encoding a type V P-type
ATPase.";
Genes Dev. 19:2757-2769(2005).
[6]
FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DISRUPTION
PHENOTYPE, AND MUTAGENESIS OF THR-699.
PubMed=19666499; DOI=10.1073/pnas.0901778106;
Ticconi C.A., Lucero R.D., Sakhonwasee S., Adamson A.W., Creff A.,
Nussaume L., Desnos T., Abel S.;
"ER-resident proteins PDR2 and LPR1 mediate the developmental response
of root meristems to phosphate availability.";
Proc. Natl. Acad. Sci. U.S.A. 106:14174-14179(2009).
-!- FUNCTION: Mediates manganese transport into the endoplasmic
reticulum. The ATPase activity is required for cellular manganese
homeostasis (By similarity). Plays an important role in pollen and
root development through its impact on protein secretion and
transport processes. Functions together with LPR1 and LPR2 in a
common pathway that adjusts root meristem activity to phosphate
availability. Under phosphate limitation, restricts SHR movement
in root meristem and is required for maintaining SCR expression in
the root meristem stem-cell niche as well as for proximal meristem
activity. Can complement the yeast spf1 mutant. {ECO:0000250,
ECO:0000269|PubMed:14996215, ECO:0000269|PubMed:16291648,
ECO:0000269|PubMed:19666499}.
-!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
-!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
{ECO:0000269|PubMed:16291648, ECO:0000269|PubMed:19666499}; Multi-
pass membrane protein {ECO:0000269|PubMed:16291648,
ECO:0000269|PubMed:19666499}. Note=Found in secretory vesicles of
the tapetum and developing pollen grains.
-!- TISSUE SPECIFICITY: Highly expressed in root meristem. Expressed
in pavement cells of trichomes, stipules, stamens and pollen
grains. {ECO:0000269|PubMed:19666499}.
-!- DISRUPTION PHENOTYPE: Imbalances in cation homeostasis and severe
reduction in fertility. Increased inhibition of primary root
growth in low inorganic phosphate conditions.
{ECO:0000269|PubMed:14996215, ECO:0000269|PubMed:16291648,
ECO:0000269|PubMed:19666499}.
-!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC
3.A.3) family. Type V subfamily. {ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=BX831910; Type=Frameshift; Positions=1100; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AB025633; BAA97238.1; -; Genomic_DNA.
EMBL; CP002688; AED93192.1; -; Genomic_DNA.
EMBL; BX831910; -; NOT_ANNOTATED_CDS; mRNA.
RefSeq; NP_197752.1; NM_122268.5.
UniGene; At.25308; -.
ProteinModelPortal; Q9LT02; -.
BioGrid; 17703; 1.
STRING; 3702.AT5G23630.1; -.
PaxDb; Q9LT02; -.
PRIDE; Q9LT02; -.
EnsemblPlants; AT5G23630.1; AT5G23630.1; AT5G23630.
GeneID; 832428; -.
Gramene; AT5G23630.1; AT5G23630.1; AT5G23630.
KEGG; ath:AT5G23630; -.
Araport; AT5G23630; -.
TAIR; locus:2171686; AT5G23630.
eggNOG; KOG0209; Eukaryota.
eggNOG; COG0474; LUCA.
HOGENOM; HOG000199432; -.
InParanoid; Q9LT02; -.
KO; K14950; -.
OMA; QVSTFAI; -.
OrthoDB; EOG093600HK; -.
PhylomeDB; Q9LT02; -.
Reactome; R-ATH-936837; Ion transport by P-type ATPases.
PRO; PR:Q9LT02; -.
Proteomes; UP000006548; Chromosome 5.
Genevisible; Q9LT02; AT.
GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0005886; C:plasma membrane; IDA:TAIR.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0005388; F:calcium-transporting ATPase activity; IBA:GO_Central.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0006874; P:cellular calcium ion homeostasis; IBA:GO_Central.
GO; GO:0006875; P:cellular metal ion homeostasis; IMP:TAIR.
GO; GO:0016036; P:cellular response to phosphate starvation; IMP:TAIR.
GO; GO:0010073; P:meristem maintenance; IMP:TAIR.
GO; GO:0009846; P:pollen germination; IMP:TAIR.
GO; GO:0010152; P:pollen maturation; IMP:TAIR.
GO; GO:0048867; P:stem cell fate determination; IMP:TAIR.
Gene3D; 3.40.1110.10; -; 1.
InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
InterPro; IPR018303; ATPase_P-typ_P_site.
InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
InterPro; IPR036412; HAD-like_sf.
InterPro; IPR006544; P-type_TPase_V.
InterPro; IPR001757; P_typ_ATPase.
SUPFAM; SSF56784; SSF56784; 3.
SUPFAM; SSF81653; SSF81653; 1.
SUPFAM; SSF81660; SSF81660; 1.
SUPFAM; SSF81665; SSF81665; 3.
TIGRFAMs; TIGR01494; ATPase_P-type; 2.
TIGRFAMs; TIGR01657; P-ATPase-V; 1.
PROSITE; PS00154; ATPASE_E1_E2; 1.
1: Evidence at protein level;
ATP-binding; Complete proteome; Endoplasmic reticulum; Hydrolase;
Magnesium; Manganese; Membrane; Metal-binding; Nucleotide-binding;
Reference proteome; Transmembrane; Transmembrane helix; Transport.
CHAIN 1 1179 Probable manganese-transporting ATPase
PDR2.
/FTId=PRO_0000046420.
TOPO_DOM 1 20 Cytoplasmic. {ECO:0000255}.
TRANSMEM 21 42 Helical. {ECO:0000255}.
TOPO_DOM 43 50 Lumenal. {ECO:0000255}.
TRANSMEM 51 71 Helical. {ECO:0000255}.
TOPO_DOM 72 192 Cytoplasmic. {ECO:0000255}.
TRANSMEM 193 215 Helical. {ECO:0000255}.
TOPO_DOM 216 218 Lumenal. {ECO:0000255}.
TRANSMEM 219 238 Helical. {ECO:0000255}.
TOPO_DOM 239 402 Cytoplasmic. {ECO:0000255}.
TRANSMEM 403 422 Helical. {ECO:0000255}.
TOPO_DOM 423 435 Lumenal. {ECO:0000255}.
TRANSMEM 436 453 Helical. {ECO:0000255}.
TOPO_DOM 454 947 Cytoplasmic. {ECO:0000255}.
TRANSMEM 948 967 Helical. {ECO:0000255}.
TOPO_DOM 968 979 Lumenal. {ECO:0000255}.
TRANSMEM 980 997 Helical. {ECO:0000255}.
TOPO_DOM 998 1013 Cytoplasmic. {ECO:0000255}.
TRANSMEM 1014 1034 Helical. {ECO:0000255}.
TOPO_DOM 1035 1059 Lumenal. {ECO:0000255}.
TRANSMEM 1060 1079 Helical. {ECO:0000255}.
TOPO_DOM 1080 1092 Cytoplasmic. {ECO:0000255}.
TRANSMEM 1093 1110 Helical. {ECO:0000255}.
TOPO_DOM 1111 1128 Lumenal. {ECO:0000255}.
TRANSMEM 1129 1148 Helical. {ECO:0000255}.
TOPO_DOM 1149 1179 Cytoplasmic. {ECO:0000255}.
COMPBIAS 1175 1178 Poly-Lys.
ACT_SITE 491 491 4-aspartylphosphate intermediate.
{ECO:0000250}.
METAL 812 812 Magnesium. {ECO:0000250}.
METAL 816 816 Magnesium. {ECO:0000250}.
MUTAGEN 699 699 T->I: In pdr2-1; increased inhibition of
primary root growth in low inorganic
phosphate conditions.
{ECO:0000269|PubMed:19666499}.
CONFLICT 935 935 D -> N (in Ref. 3; BX831910).
{ECO:0000305}.
CONFLICT 995 995 S -> F (in Ref. 3; BX831910).
{ECO:0000305}.
SEQUENCE 1179 AA; 131115 MW; 4A3E82D2222A4D78 CRC64;
MSSFRVGGKV VEKVDLCRKK QLVWRLDVWP FAILYTVWLT TIVPSIDFSD ACIALGGLSA
FHILVLLFTT WSVDFKCFVQ FSKVNSIDQA DACKVTPAKF SGSKEVVPLH FRSQMTDSAS
SGDMEEIFFD FRKQRFIYSK ELGAFSKLPY PTKETFGHYL KCTGHGTEAK IATATEKWGR
NVFDYPQPTF QKLMKENCME PFFVFQVFCV GLWCLDEFWY YSVFTLFMLF MFESTMAKSR
LKTLTDLRSV RVDSQTVMVY RSGKWVKLLG TDLLPGDVVS IGRPSTQTGG EDKTVPADML
LLVGSAIVNE AILTGESTPQ WKVPIVGQRS DEKLSIKRNK NHVLFGGTKI LQHSPDKSFS
LKTPDGGCLA VVLRTGFETS QGKLMRTILF STERVTANSW ESGLFILFLV VFAVIAAGYV
LVKGLEDPTR SKYKLLLGCS LIITSVIPPE LPMELSIAVN TSLLALVRRG IFCTEPFRIP
FAGKVDLCCF DKTGTLTSDD MEFRGVGGLS NCEEAETDMS KVPVRTLEIL ASCHALVFVE
NKLVGDPLEK AALKGIDWSY KADEKALPRR GNGNSVQIMQ RYHFASHLKR MSVIVRIQEE
YLAFVKGAPE TIQERLVDVP AQYIETYKRY TRQGSRVLAL AYKRLPDMMV SEARDMDRDA
VESDLTFAGF AVFNCPIRPD SAPVLLELKN SSHDLVMITG DQALTACHVA GQVHIVSNPV
LILGRSGSGN EYKWVSPDEK EIIPYSEKEI ETLAETHDLC IGGDSIEMLQ ATSAVLRVIP
FVKVFARVAP QQKELILTTF KAVGRGTLMC GDGTNDVGAL KQAHVGVALL NNKLPLSPSD
SSKDDKSKSK KSKLPLEPAS KTITQNGEGS SKGKIPPQNR HLTAAELQRQ KLKKIMDDLN
NDEGDGRSAP LVKLGDASMA SPFTAKHASV APVTDIIRQG RSTLVTTLQM FKILGLNCLA
TAYVLSVMYL DGVKLGDVQA TISGVLTAAF FLFISHARPL QTLSAERPHP SVFSVYLFLS
LIGQFAVHLT FLVYSVKEAE KHMPEECIEP DASFHPNLVN TVSYMVSMML QVATFAVNYM
GHPFNQSIRE NKPFFYALIA GAGFFTVIAS DLFRDLNDSL KLVPLPQGLR DKLLIWASLM
FIICYSWERL LRWAFPGKIS SWKHKQRAVT ANLEKKKKV


Related products :

Catalog number Product name Quantity
EIAAB34264 ATP6AP2,ATP6IP2,ATP6M8-9,ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,CAPER,ELDF10,Embryonic liver differentiation factor 10,ER-local
EIAAB34265 ATP6AP2,ATP6IP2,ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,Bos taurus,Bovine,Renin receptor,Renin_prorenin receptor,Vacuolar ATP sy
EIAAB34267 Atp6ap2,Atp6ip2,ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,Mouse,Mus musculus,Renin receptor,Renin_prorenin receptor
EIAAB34266 Atp6ap2,Atp6ip2,ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,Rat,Rattus norvegicus,Renin receptor,Renin_prorenin receptor
EIAAB27268 Mouse,Mus musculus,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 2,Nkain2,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 2,Tcba1,T-cell lymphoma breakpoint
EIAAB27269 FAM77B,Homo sapiens,Human,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 2,NKAIN2,Protein FAM77B,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 2,TCBA1,T-ce
EIAAB27273 C20orf58,FAM77A,Homo sapiens,Human,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 4,NKAIN4,Protein FAM77A,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 4
EIAAB27265 FAM77C,Homo sapiens,Human,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 1,NKAIN1,Protein FAM77C,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 1
EIAAB27271 FAM77D,Homo sapiens,Human,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 3,NKAIN3,Protein FAM77D,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 3
EIAAB27272 Fam77a,Mouse,Mus musculus,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 4,Nkain4,Protein FAM77A,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 4
EIAAB27270 Fam77d,Mouse,Mus musculus,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 3,Nkain3,Protein FAM77D,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 3
EIAAB27266 Fam77c,Mouse,Mus musculus,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 1,Nkain1,Protein FAM77C,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 1
EIAAB27267 Bos taurus,Bovine,Na(+)_K(+)-transporting ATPase subunit beta-1-interacting protein 2,NKAIN2,Sodium_potassium-transporting ATPase subunit beta-1-interacting protein 2
E1446c Rat ELISA Kit FOR Probable phospholipid-transporting ATPase IIB 96T
bs-1152P Peptides: ATP1b2_Na+K+ ATPase(ATPase, Na+_K+ transporting, beta 2 polypeptide) Protein Length:12-25 amino acids. 200ug lyophilized
EH2280 Probable cation-transporting ATPase 13A2 Elisa Kit 96T
E1057d Human ELISA Kit FOR Probable phospholipid-transporting ATPase IM 96T
E2000r Mouse ELISA Kit FOR Probable phospholipid-transporting ATPase IH 96T
AT11C_HUMAN Human ELISA Kit FOR Probable phospholipid-transporting ATPase IG 96T
E10871r Human ELISA Kit FOR Probable phospholipid-transporting ATPase VD 96T
CSB-EL002417HU Human Probable phospholipid-transporting ATPase IB(ATP8A2) ELISA kit 96T
G1346 Probable phospholipid-transporting ATPase IH (ATP11A), Mouse, ELISA Kit 96T
CSB-EL002310HU Human Probable phospholipid-transporting ATPase VA(ATP10A) ELISA kit 96T
CSB-EL002311HU Human Probable phospholipid-transporting ATPase VB(ATP10B) ELISA kit 96T
G1335 Probable phospholipid-transporting ATPase IB (ATP8A2), Human, ELISA Kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur