Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Probable tRNA sulfurtransferase (EC 2.8.1.4) (Sulfur carrier protein ThiS sulfurtransferase) (Thiamine biosynthesis protein ThiI) (tRNA 4-thiouridine synthase)

 A0A1B4X5U8_9PSED        Unreviewed;       465 AA.
A0A1B4X5U8;
02-NOV-2016, integrated into UniProtKB/TrEMBL.
02-NOV-2016, sequence version 1.
25-OCT-2017, entry version 10.
RecName: Full=Probable tRNA sulfurtransferase {ECO:0000256|HAMAP-Rule:MF_00021};
EC=2.8.1.4 {ECO:0000256|HAMAP-Rule:MF_00021};
AltName: Full=Sulfur carrier protein ThiS sulfurtransferase {ECO:0000256|HAMAP-Rule:MF_00021};
AltName: Full=Thiamine biosynthesis protein ThiI {ECO:0000256|HAMAP-Rule:MF_00021};
AltName: Full=tRNA 4-thiouridine synthase {ECO:0000256|HAMAP-Rule:MF_00021};
Name=thiI {ECO:0000256|HAMAP-Rule:MF_00021};
ORFNames=LAB08_4895 {ECO:0000313|EMBL:BAV30165.1};
Pseudomonas sp. LAB-08.
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
Pseudomonadaceae; Pseudomonas.
NCBI_TaxID=143813 {ECO:0000313|EMBL:BAV30165.1};
[1] {ECO:0000313|EMBL:BAV30165.1}
NUCLEOTIDE SEQUENCE.
Suzuki K., Fatma A., Inuzuka Y., Tashiro Y., Futamata H.;
"Draft genome sequence of Pseudomonassp. LAB-08 isolated from TCE
contaminated aquifer soil.";
Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Catalyzes the ATP-dependent transfer of a sulfur to tRNA
to produce 4-thiouridine in position 8 of tRNAs, which functions
as a near-UV photosensor. Also catalyzes the transfer of sulfur to
the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.
This is a step in the synthesis of thiazole, in the thiamine
biosynthesis pathway. The sulfur is donated as persulfide by IscS.
{ECO:0000256|HAMAP-Rule:MF_00021, ECO:0000256|SAAS:SAAS00848766}.
-!- CATALYTIC ACTIVITY: ATP + [ThiI sulfur-carrier protein]-S-
sulfanyl-L-cysteine + uracil in tRNA + 2 reduced ferredoxin [iron-
sulfur] cluster = AMP + diphosphate + 4-thiouracil in tRNA + [ThiI
sulfur-carrier protein]-L-cysteine + 2 oxidized ferredoxin [iron-
sulfur] cluster. {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00860091}.
-!- CATALYTIC ACTIVITY: [IscS]-SSH + [ThiS]-COAMP = [IscS]-SH +
[ThiS]-COSH + AMP. {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00848762}.
-!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
{ECO:0000256|HAMAP-Rule:MF_00021, ECO:0000256|SAAS:SAAS00848764}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00848759}.
-!- SIMILARITY: Belongs to the ThiI family. {ECO:0000256|HAMAP-
Rule:MF_00021, ECO:0000256|SAAS:SAAS00848754}.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00021}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AP017423; BAV30165.1; -; Genomic_DNA.
UniPathway; UPA00060; -.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
GO; GO:0016783; F:sulfurtransferase activity; IEA:UniProtKB-UniRule.
GO; GO:0004810; F:tRNA adenylyltransferase activity; IEA:InterPro.
GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-UniRule.
GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
GO; GO:0052837; P:thiazole biosynthetic process; IEA:InterPro.
GO; GO:0034227; P:tRNA thio-modification; IEA:UniProtKB-UniRule.
CDD; cd01712; ThiI; 1.
Gene3D; 3.40.250.10; -; 1.
Gene3D; 3.40.50.620; -; 1.
HAMAP; MF_00021; ThiI; 1.
InterPro; IPR036873; Rhodanese-like_dom_sf.
InterPro; IPR014729; Rossmann-like_a/b/a_fold.
InterPro; IPR026340; Thiazole_biosynth_dom.
InterPro; IPR020536; ThiI_AANH.
InterPro; IPR004114; THUMP_dom.
InterPro; IPR003720; tRNA_STrfase.
Pfam; PF02568; ThiI; 1.
Pfam; PF02926; THUMP; 1.
SMART; SM00981; THUMP; 1.
SUPFAM; SSF52821; SSF52821; 1.
TIGRFAMs; TIGR04271; ThiI_C_thiazole; 1.
TIGRFAMs; TIGR00342; TIGR00342; 1.
PROSITE; PS51165; THUMP; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00023005};
Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00848768};
Disulfide bond {ECO:0000256|SAAS:SAAS00898280};
Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00023005};
Redox-active center {ECO:0000256|SAAS:SAAS00898282};
RNA-binding {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00848757};
Thiamine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00848763};
Transferase {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00848758};
tRNA-binding {ECO:0000256|HAMAP-Rule:MF_00021,
ECO:0000256|SAAS:SAAS00848757}.
DOMAIN 44 148 THUMP. {ECO:0000259|PROSITE:PS51165}.
NP_BIND 166 167 ATP. {ECO:0000256|HAMAP-Rule:MF_00021}.
BINDING 248 248 ATP. {ECO:0000256|HAMAP-Rule:MF_00021}.
BINDING 270 270 ATP; via amide nitrogen.
{ECO:0000256|HAMAP-Rule:MF_00021}.
BINDING 279 279 ATP. {ECO:0000256|HAMAP-Rule:MF_00021}.
SEQUENCE 465 AA; 52157 MW; 5802F40CB51CD4E6 CRC64;
MRFIRQLAKN IRAVLRDLDP AVVVNGVWDN LELETRVSDP KALKEMGERL SCMPGIAHFL
QIDEYPLGDF DDIVEKCKQH YGDALAGKIF SVRCKRAGKH PFSSIDIEKY VGSQLRRQCG
AAGIDLKKPE IEVRIEVRDQ RLFVIHSQHN GIGGYPLGAL EQTLVLMSGG FDSTVAAYQI
MRRGLMAHFC FFNLGGRAHE LGVMEVAHFI WKKYGSSQRV LFVSVPFEEV LGEILGKVDN
SHMGVVLKRM MLRASSQIAD RLHIEALVTG EAISQVSSQT LPNLSVIDCV TDKLVLRPLI
ASHKQDIIDT ANEIGTADFA RHMPEYCGVI SVNPKTAAKR YRVEHEEKEF DMAVLERALE
NAKLVPIDRV IDELGQDLQI EEVSDALAGQ IVIDIRHPDA AEDDPLELAG IEVQTMPFYA
LNARFKELDP TRQYLLYCDK GVMSRLHAHH LLSEGHANVR VYRPS


Related products :

Catalog number Product name Quantity
EIAAB33196 Ccdc139,Coiled-coil domain-containing protein 139,Mouse,Mus musculus,Psi55 synthase,Pus10,Putative tRNA pseudouridine synthase Pus10,tRNA pseudouridine 55 synthase,tRNA pseudouridylate synthase,tRNA-u
EIAAB33197 CCDC139,Coiled-coil domain-containing protein 139,DOBI,Homo sapiens,Human,Psi55 synthase,PUS10,Putative tRNA pseudouridine synthase Pus10,tRNA pseudouridine 55 synthase,tRNA pseudouridylate synthase,t
U1045m CLIA D5Ertd135e,Mouse,Mus musculus,O-phosphoseryl-tRNA(Sec) selenium transferase,Sec synthase,Selenocysteine synthase,Selenocysteinyl-tRNA(Sec) synthase,SepSecS,Sepsecs,Sep-tRNA Sec-tRNA synthase,UGA 96T
E1045m ELISA D5Ertd135e,Mouse,Mus musculus,O-phosphoseryl-tRNA(Sec) selenium transferase,Sec synthase,Selenocysteine synthase,Selenocysteinyl-tRNA(Sec) synthase,SepSecS,Sepsecs,Sep-tRNA Sec-tRNA synthase,UGA 96T
E1045m ELISA kit D5Ertd135e,Mouse,Mus musculus,O-phosphoseryl-tRNA(Sec) selenium transferase,Sec synthase,Selenocysteine synthase,Selenocysteinyl-tRNA(Sec) synthase,SepSecS,Sepsecs,Sep-tRNA Sec-tRNA synthas 96T
EIAAB44137 MNCb-0873,Mouse,Mus musculus,Pus1,tRNA pseudouridine synthase A, mitochondrial,tRNA pseudouridine(38-40) synthase,tRNA pseudouridylate synthase I,tRNA-uridine isomerase I
EIAAB44136 Homo sapiens,Human,PP8985,PUS1,tRNA pseudouridine synthase A, mitochondrial,tRNA pseudouridine(38-40) synthase,tRNA pseudouridylate synthase I,tRNA-uridine isomerase I
EIAAB44135 Pus1,Rat,Rattus norvegicus,tRNA pseudouridine synthase A, mitochondrial,tRNA pseudouridine(38-40) synthase,tRNA pseudouridylate synthase I,tRNA-uridine isomerase I
E0025m Mouse ELISA Kit FOR Probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep 96T
STRN_HUMAN Mouse ELISA Kit FOR Probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep 96T
E1612c Human ELISA Kit FOR Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP 96T
ATP5H_BOVIN Mouse ELISA Kit FOR Probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep 96T
EIAAB29259 GCPL1,Homo sapiens,hOSGEP,Human,OSGEP,Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP,t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP
EIAAB33200 FKSG32,Homo sapiens,Human,PUS3,tRNA pseudouridine synthase 3,tRNA pseudouridylate synthase 3,tRNA-uridine isomerase 3
EIAAB33206 Homo sapiens,Human,PUSL1,tRNA pseudouridine synthase-like 1,tRNA pseudouridylate synthase-like 1,tRNA-uridine isomerase-like 1
EIAAB40912 Homo sapiens,Human,Probable threonyl-tRNA synthetase 2, cytoplasmic,TARSL2,Threonine--tRNA ligase,Threonyl-tRNA synthetase-like protein 2,ThrRS
EIAAB33198 Mouse,Mus musculus,Pus3,tRNA pseudouridine synthase 3,tRNA pseudouridylate synthase 3,tRNA-uridine isomerase 3
EIAAB33205 Mouse,Mus musculus,Pusl1,tRNA pseudouridine synthase-like 1,tRNA pseudouridylate synthase-like 1,tRNA-uridine isomerase-like 1
EIAAB33199 Bos taurus,Bovine,PUS3,tRNA pseudouridine synthase 3,tRNA pseudouridylate synthase 3,tRNA-uridine isomerase 3
EIAAB40910 Mouse,Mus musculus,Probable threonyl-tRNA synthetase 2, cytoplasmic,Tarsl2,Threonine--tRNA ligase,Threonyl-tRNA synthetase-like protein 2,ThrRS
EIAAB40911 Bos taurus,Bovine,Probable threonyl-tRNA synthetase 2, cytoplasmic,TARSL2,Threonine--tRNA ligase,Threonyl-tRNA synthetase-like protein 2,ThrRS
E1045h ELISA kit Homo sapiens,Human,Liver-pancreas antigen,LP,O-phosphoseryl-tRNA(Sec) selenium transferase,Sec synthase,Selenocysteine synthase,Selenocysteinyl-tRNA(Sec) synthase,SepSecS,SEPSECS,Sep-tRNA S 96T
E1045h ELISA Homo sapiens,Human,Liver-pancreas antigen,LP,O-phosphoseryl-tRNA(Sec) selenium transferase,Sec synthase,Selenocysteine synthase,Selenocysteinyl-tRNA(Sec) synthase,SepSecS,SEPSECS,Sep-tRNA Sec-tR 96T
U1045h CLIA Homo sapiens,Human,Liver-pancreas antigen,LP,O-phosphoseryl-tRNA(Sec) selenium transferase,Sec synthase,Selenocysteine synthase,Selenocysteinyl-tRNA(Sec) synthase,SepSecS,SEPSECS,Sep-tRNA Sec-tRN 96T
EIAAB29257 Gcpl1,Osgep,Probable tRNA threonylcarbamoyladenosine biosynthesis protein Osgep,Rat,Rattus norvegicus,t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur