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Protein FAM133B

 F133B_MOUSE             Reviewed;         245 AA.
Q9CVI2; B2RVR0; Q78HY5;
15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
03-OCT-2012, sequence version 3.
12-SEP-2018, entry version 94.
RecName: Full=Protein FAM133B;
Name=Fam133b;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), AND NUCLEOTIDE
SEQUENCE [LARGE SCALE MRNA] OF 1-127 (ISOFORM 1).
STRAIN=C57BL/6J; TISSUE=Small intestine, and Testis;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C57BL/6J;
PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
Lindblad-Toh K., Eichler E.E., Ponting C.P.;
"Lineage-specific biology revealed by a finished genome assembly of
the mouse.";
PLoS Biol. 7:E1000112-E1000112(2009).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
STRAIN=C57BL/6J; TISSUE=Brain, and Retina;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[4]
PROTEIN SEQUENCE OF 171-179, AND IDENTIFICATION BY MASS SPECTROMETRY.
STRAIN=OF1; TISSUE=Hippocampus;
Lubec G., Sunyer B., Chen W.-Q.;
Submitted (JAN-2009) to UniProtKB.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1;
IsoId=Q9CVI2-1; Sequence=Displayed;
Name=2;
IsoId=Q9CVI2-2; Sequence=VSP_025572, VSP_025573;
Note=May be produced at very low levels due to a premature stop
codon in the mRNA, leading to nonsense-mediated mRNA decay.;
-!- SIMILARITY: Belongs to the FAM133 family. {ECO:0000305}.
-----------------------------------------------------------------------
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EMBL; AK008115; BAB25470.1; -; mRNA.
EMBL; AK161505; BAE36429.1; -; mRNA.
EMBL; AC090443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC147310; AAI47311.1; -; mRNA.
EMBL; BC147311; AAI47312.1; -; mRNA.
EMBL; BC027051; -; NOT_ANNOTATED_CDS; mRNA.
CCDS; CCDS39000.1; -. [Q9CVI2-1]
RefSeq; NP_001035966.1; NM_001042501.1. [Q9CVI2-1]
UniGene; Mm.240265; -.
ProteinModelPortal; Q9CVI2; -.
iPTMnet; Q9CVI2; -.
PhosphoSitePlus; Q9CVI2; -.
EPD; Q9CVI2; -.
PaxDb; Q9CVI2; -.
PeptideAtlas; Q9CVI2; -.
PRIDE; Q9CVI2; -.
Ensembl; ENSMUST00000115527; ENSMUSP00000111189; ENSMUSG00000058503. [Q9CVI2-1]
GeneID; 68152; -.
KEGG; mmu:68152; -.
UCSC; uc008wgx.1; mouse. [Q9CVI2-2]
UCSC; uc008wgy.1; mouse. [Q9CVI2-1]
CTD; 257415; -.
MGI; MGI:1915402; Fam133b.
eggNOG; ENOG410IY68; Eukaryota.
eggNOG; ENOG41123P0; LUCA.
GeneTree; ENSGT00730000111097; -.
HOGENOM; HOG000059590; -.
HOVERGEN; HBG088046; -.
InParanoid; Q9CVI2; -.
OMA; MYPEDKP; -.
OrthoDB; EOG091G0ZD9; -.
PhylomeDB; Q9CVI2; -.
TreeFam; TF350193; -.
PRO; PR:Q9CVI2; -.
Proteomes; UP000000589; Chromosome 5.
Bgee; ENSMUSG00000058503; Expressed in 267 organ(s), highest expression level in embryo.
CleanEx; MM_5830415L20RIK; -.
ExpressionAtlas; Q9CVI2; baseline and differential.
Genevisible; Q9CVI2; MM.
InterPro; IPR026766; Fam133.
PANTHER; PTHR31911; PTHR31911; 1.
1: Evidence at protein level;
Alternative splicing; Complete proteome; Direct protein sequencing;
Phosphoprotein; Reference proteome.
CHAIN 1 245 Protein FAM133B.
/FTId=PRO_0000287617.
COMPBIAS 45 236 Lys-rich.
COMPBIAS 82 158 Ser-rich.
MOD_RES 82 82 Phosphoserine.
{ECO:0000250|UniProtKB:Q5BKY9}.
MOD_RES 190 190 Phosphoserine.
{ECO:0000250|UniProtKB:Q5BKY9}.
MOD_RES 191 191 Phosphoserine.
{ECO:0000250|UniProtKB:Q5BKY9}.
MOD_RES 193 193 Phosphoserine.
{ECO:0000250|UniProtKB:Q5BKY9}.
MOD_RES 195 195 Phosphoserine.
{ECO:0000250|UniProtKB:Q5BKY9}.
VAR_SEQ 104 115 YSSSSSSSSDSS -> VSKSFLFSKCYS (in isoform
2). {ECO:0000303|PubMed:15489334,
ECO:0000303|PubMed:16141072}.
/FTId=VSP_025572.
VAR_SEQ 116 245 Missing (in isoform 2).
{ECO:0000303|PubMed:15489334,
ECO:0000303|PubMed:16141072}.
/FTId=VSP_025573.
CONFLICT 81 81 L -> I (in Ref. 1; BAB25470).
{ECO:0000305}.
SEQUENCE 245 AA; 27952 MW; F816A4DFC6AFB88B CRC64;
MGKRDNRVAY MNPIAMARSR GPIQSSGPTI QDYLNRPRPT WEEVKEQLEK KKKGSKALAE
FEEKMNENWK KELEKHREKL LSGNESSSKK RQKKKKEKKK SGRYSSSSSS SSDSSSSSSD
SEDEDKKQTK RRKKKKSRCH KSPESSGSDS ASDSKDGSKK KKKSKDVTER EKDTKGLSKK
RKMYEDKPLS SESLSESDCG EVQAKRKKSG EERERTTDKA KKRRKHKKHS KKKKKKAASS
SSDSP


Related products :

Catalog number Product name Quantity
F133B_HUMAN ELISA Kit FOR Protein FAM133B; organism: Human; gene name: FAM133B 96T
F133B_MOUSE ELISA Kit FOR Protein FAM133B; organism: Mouse; gene name: Fam133b 96T
CSB-EL008061HU Human Protein FAM133B(FAM133B) ELISA kit SpeciesHuman 96T
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CSB-EL008061MO Mouse Protein FAM133B(FAM133B) ELISA kit 96T
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i007578d FAM133B siRNA_Lentivectors 500ng
i007578c FAM133B siRNA_Lentivectors 500ng
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NBL1-10474 FAM133B Lysate 0.1 mg


 

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