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Protein FAM74A4/A6

 FAM74_HUMAN             Reviewed;         123 AA.
Q5TZK3; A6NH89; Q6ZSU6;
12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
05-JUL-2005, sequence version 1.
18-JUL-2018, entry version 66.
RecName: Full=Protein FAM74A4/A6 {ECO:0000305};
Name=FAM74A4 {ECO:0000312|HGNC:HGNC:32032};
Synonyms=FAM74A2 {ECO:0000312|HGNC:HGNC:32032};
and
Name=FAM74A6 {ECO:0000312|HGNC:HGNC:34036};
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Caudate nucleus;
PubMed=14702039; DOI=10.1038/ng1285;
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human
cDNAs.";
Nat. Genet. 36:40-45(2004).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=15164053; DOI=10.1038/nature02465;
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E.,
Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C.,
Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S.,
Babbage A.K., Babbage S., Bagguley C.L., Bailey J., Banerjee R.,
Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P.,
Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W.,
Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G.,
Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M.,
Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W.,
Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A.,
Frankland J.A., French L., Fricker D.G., Garner P., Garnett J.,
Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
Kimberley A.M., King A., Knights A., Laird G.K., Langford C.,
Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M.,
Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S.,
McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J.,
Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R.,
Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M.,
Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M.,
Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A.,
Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P.,
Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W.,
Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M.,
Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S.,
Rogers J., Dunham I.;
"DNA sequence and analysis of human chromosome 9.";
Nature 429:369-374(2004).
-!- INTERACTION:
Q15834:CCDC85B; NbExp=3; IntAct=EBI-10247271, EBI-739674;
O95273:CCNDBP1; NbExp=5; IntAct=EBI-10247271, EBI-748961;
Q9C0F1:CEP44; NbExp=3; IntAct=EBI-10247271, EBI-744115;
O95967:EFEMP2; NbExp=5; IntAct=EBI-10247271, EBI-743414;
Q92979:EMG1; NbExp=5; IntAct=EBI-10247271, EBI-718638;
Q6NT76:HMBOX1; NbExp=3; IntAct=EBI-10247271, EBI-2549423;
Q13422:IKZF1; NbExp=3; IntAct=EBI-10247271, EBI-745305;
Q15323:KRT31; NbExp=5; IntAct=EBI-10247271, EBI-948001;
Q6A162:KRT40; NbExp=5; IntAct=EBI-10247271, EBI-10171697;
P60370:KRTAP10-5; NbExp=3; IntAct=EBI-10247271, EBI-10172150;
P60409:KRTAP10-7; NbExp=3; IntAct=EBI-10247271, EBI-10172290;
P60410:KRTAP10-8; NbExp=5; IntAct=EBI-10247271, EBI-10171774;
P60411:KRTAP10-9; NbExp=3; IntAct=EBI-10247271, EBI-10172052;
Q9BYR5:KRTAP4-2; NbExp=3; IntAct=EBI-10247271, EBI-10172511;
P26371:KRTAP5-9; NbExp=5; IntAct=EBI-10247271, EBI-3958099;
Q9BRK4:LZTS2; NbExp=3; IntAct=EBI-10247271, EBI-741037;
P50222:MEOX2; NbExp=3; IntAct=EBI-10247271, EBI-748397;
Q5JR59:MTUS2; NbExp=3; IntAct=EBI-10247271, EBI-742948;
Q7Z3S9:NOTCH2NL; NbExp=5; IntAct=EBI-10247271, EBI-945833;
Q5VU43:PDE4DIP; NbExp=3; IntAct=EBI-10247271, EBI-1105124;
Q8IXK0:PHC2; NbExp=3; IntAct=EBI-10247271, EBI-713786;
Q96KN7:RPGRIP1; NbExp=3; IntAct=EBI-10247271, EBI-1050213;
O75558:STX11; NbExp=3; IntAct=EBI-10247271, EBI-714135;
P15884:TCF4; NbExp=3; IntAct=EBI-10247271, EBI-533224;
-!- SIMILARITY: Belongs to the FAM74 family. {ECO:0000305}.
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EMBL; AK127145; BAC86850.1; -; mRNA.
EMBL; AL590491; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BX005040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
UniGene; Hs.741141; -.
UniGene; Hs.742601; -.
SMR; Q5TZK3; -.
IntAct; Q5TZK3; 34.
iPTMnet; Q5TZK3; -.
PhosphoSitePlus; Q5TZK3; -.
PRIDE; Q5TZK3; -.
ProteomicsDB; 65221; -.
GeneCards; FAM74A4; -.
GeneCards; FAM74A6; -.
HGNC; HGNC:32032; FAM74A4.
HGNC; HGNC:34036; FAM74A6.
neXtProt; NX_Q5TZK3; -.
InParanoid; Q5TZK3; -.
PhylomeDB; Q5TZK3; -.
PRO; PR:Q5TZK3; -.
Proteomes; UP000005640; Unplaced.
1: Evidence at protein level;
Complete proteome; Reference proteome.
CHAIN 1 123 Protein FAM74A4/A6.
/FTId=PRO_0000266047.
CONFLICT 13 13 V -> L (in Ref. 1; BAC86850).
{ECO:0000305}.
SEQUENCE 123 AA; 14773 MW; 1DAC8479980565FF CRC64;
MWRELRGCPG GDVETAQRLS QRRRGKSSEA VPEKTWRAQR MSQRRRGESS EAVPEKTWKE
LRNSETVPEK TWKQLRGCLQ EDVQRVQRLS RRRHGESSKA VHKKMWREFR GCRYCCTWLF
FFG


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