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Protein Tat (Transactivating regulatory protein)

 Q9Q6W1_9HIV1            Unreviewed;        86 AA.
Q9Q6W1;
01-MAY-2000, integrated into UniProtKB/TrEMBL.
01-MAY-2000, sequence version 1.
12-SEP-2018, entry version 71.
RecName: Full=Protein Tat {ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00396010};
Name=tat {ECO:0000313|EMBL:AAF22326.1};
HIV-1 CRF03_AB.
Viruses; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
NCBI_TaxID=540995 {ECO:0000313|EMBL:AAF22326.1, ECO:0000313|Proteomes:UP000107373};
[1] {ECO:0000313|EMBL:AAF22326.1, ECO:0000313|Proteomes:UP000107373}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KAL153 {ECO:0000313|EMBL:AAF22326.1};
PubMed=10933619; DOI=10.1089/08892220050075309;
Liitsola K., Holm K., Bobkov A., Pokrovsky V., Smolskaya T.,
Leinikki P., Osmanov S., Salminen M.;
"An AB recombinant and its parental HIV type 1 strains in the area of
the former Soviet Union: low requirements for sequence identity in
recombination. UNAIDS Virus Isolation Network.";
AIDS Res. Hum. Retroviruses 16:1047-1053(2000).
-!- SUBCELLULAR LOCATION: Host nucleus, host nucleolus
{ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00581732}.
-!- SIMILARITY: Belongs to the lentiviruses Tat family.
{ECO:0000256|RuleBase:RU003311, ECO:0000256|SAAS:SAAS00581731}.
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EMBL; AF193276; AAF22326.1; -; Genomic_DNA.
ProteinModelPortal; Q9Q6W1; -.
Proteomes; UP000107373; Genome.
GO; GO:0044196; C:host cell nucleolus; IEA:UniProtKB-SubCell.
GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO; GO:0001070; F:RNA-binding transcription regulator activity; IEA:InterPro.
GO; GO:0050434; P:positive regulation of viral transcription; IEA:InterPro.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
Gene3D; 4.10.20.10; -; 1.
HAMAP; MF_04079; HIV_TAT; 1.
InterPro; IPR001831; IV_Tat.
InterPro; IPR036963; Tat_dom_sf.
Pfam; PF00539; Tat; 1.
PRINTS; PR00055; HIVTATDOMAIN.
3: Inferred from homology;
Activator {ECO:0000256|RuleBase:RU003311,
ECO:0000256|SAAS:SAAS00111091};
Complete proteome {ECO:0000313|Proteomes:UP000107373};
Host nucleus {ECO:0000256|RuleBase:RU003311,
ECO:0000256|SAAS:SAAS00473431};
Host-virus interaction {ECO:0000256|SAAS:SAAS00111166};
Reference proteome {ECO:0000313|Proteomes:UP000107373};
RNA-binding {ECO:0000256|RuleBase:RU003311,
ECO:0000256|SAAS:SAAS00111359};
Transcription {ECO:0000256|RuleBase:RU003311,
ECO:0000256|SAAS:SAAS00111074};
Transcription regulation {ECO:0000256|RuleBase:RU003311,
ECO:0000256|SAAS:SAAS00111074}.
SEQUENCE 86 AA; 9808 MW; 85ACC0B25851ADBD CRC64;
MEPVDPRLEP WKHPGSQPKT ACTNCYCKKC CLHCQVCFMK KGLGISYGRK KRRQRRRAPQ
DNQTDQVSLP KQPASQPRGD PTGPKE


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