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Putative RAD2-like endonuclease 095R (EC 3.1.-.-)

 095R_FRG3G              Reviewed;         363 AA.
Q6GZN0;
28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
19-JUL-2004, sequence version 1.
23-MAY-2018, entry version 56.
RecName: Full=Putative RAD2-like endonuclease 095R;
EC=3.1.-.-;
ORFNames=FV3-095R;
Frog virus 3 (isolate Goorha) (FV-3).
Viruses; dsDNA viruses, no RNA stage; Iridoviridae; Alphairidovirinae;
Ranavirus.
NCBI_TaxID=654924;
NCBI_TaxID=8295; Ambystoma (mole salamanders).
NCBI_TaxID=30343; Dryophytes versicolor (chameleon treefrog).
NCBI_TaxID=8404; Lithobates pipiens (Northern leopard frog) (Rana pipiens).
NCBI_TaxID=8316; Notophthalmus viridescens (Eastern newt) (Triturus viridescens).
NCBI_TaxID=45438; Rana sylvatica (Wood frog).
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=15165820; DOI=10.1016/j.virol.2004.02.019;
Tan W.G., Barkman T.J., Gregory Chinchar V., Essani K.;
"Comparative genomic analyses of frog virus 3, type species of the
genus Ranavirus (family Iridoviridae).";
Virology 323:70-84(2004).
-!- FUNCTION: Probable endonuclease. {ECO:0000305}.
-!- COFACTOR:
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Note=Binds 2 magnesium ions per subunit. {ECO:0000250};
-!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000250}.
-!- SIMILARITY: Belongs to the XPG/RAD2 endonuclease family.
{ECO:0000305}.
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EMBL; AY548484; AAT09755.1; -; Genomic_DNA.
RefSeq; YP_031674.1; NC_005946.1.
ProteinModelPortal; Q6GZN0; -.
PRIDE; Q6GZN0; -.
GeneID; 2947788; -.
KEGG; vg:2947788; -.
OrthoDB; VOG090000XR; -.
Proteomes; UP000008770; Genome.
GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO; GO:0003677; F:DNA binding; IEA:InterPro.
GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0006281; P:DNA repair; IEA:InterPro.
InterPro; IPR036279; 5-3_exonuclease_C_sf.
InterPro; IPR008918; HhH2.
InterPro; IPR029060; PIN-like_dom_sf.
InterPro; IPR006086; XPG-I_dom.
InterPro; IPR006084; XPG/Rad2.
InterPro; IPR006085; XPG_DNA_repair_N.
PANTHER; PTHR11081; PTHR11081; 1.
Pfam; PF00867; XPG_I; 1.
Pfam; PF00752; XPG_N; 1.
PRINTS; PR00853; XPGRADSUPER.
SMART; SM00279; HhH2; 1.
SMART; SM00484; XPGI; 1.
SMART; SM00485; XPGN; 1.
SUPFAM; SSF47807; SSF47807; 1.
SUPFAM; SSF88723; SSF88723; 2.
3: Inferred from homology;
Complete proteome; Endonuclease; Host nucleus; Hydrolase; Magnesium;
Metal-binding; Nuclease; Reference proteome.
CHAIN 1 363 Putative RAD2-like endonuclease 095R.
/FTId=PRO_0000410578.
SEQUENCE 363 AA; 40621 MW; A200449B8156A014 CRC64;
MGIKGLKPLL RSYGVHEYTV PLSQMSGKTI AVDGTFLLHK YKNCHSVPWH YLTLYTLSNL
RLRNVKVLFI FDGMSPPEKS REKSNRRCRK QALMEKGTLV KAQLEVWKKD GGEQAPELAA
VSERLVKTRG LDPSLTDPET VQVLTDYVDN MSRDTRVTSD DYELMRRSLD AFGFPYADAP
DEAELCCVRV VQMGIADAPM TIDSDALACG ALHGVDVVYT DLHGETLTAM STSKSKEALG
LNGEQFMDLC VMCGTDFNQR VHKLGPVTAL KLIKAHGSIE NIPSAAPSMS CLEAVRTREI
LSGGDMESRR KDYEAMVQKP VSAELIRSVF PPEFLDKLLH ENWQLRDAMK RMAPEAFEKC
KRK


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