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Putative arsenate reductase (EC 1.20.4.1)

 ARSC_NEIMA              Reviewed;         117 AA.
P63621; A1IP98; Q9JQU0;
11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
11-OCT-2004, sequence version 1.
25-OCT-2017, entry version 77.
RecName: Full=Putative arsenate reductase;
EC=1.20.4.1;
Name=arsC; OrderedLocusNames=NMA0252;
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491).
Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
Neisseriaceae; Neisseria.
NCBI_TaxID=122587;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Z2491;
PubMed=10761919; DOI=10.1038/35006655;
Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T.,
Davies R.M., Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S.,
Jagels K., Leather S., Moule S., Mungall K.L., Quail M.A.,
Rajandream M.A., Rutherford K.M., Simmonds M., Skelton J.,
Whitehead S., Spratt B.G., Barrell B.G.;
"Complete DNA sequence of a serogroup A strain of Neisseria
meningitidis Z2491.";
Nature 404:502-506(2000).
-!- FUNCTION: Reduction of arsenate [As(V)] to arsenite [As(III)].
{ECO:0000305}.
-!- CATALYTIC ACTIVITY: Arsenate + glutaredoxin = arsenite +
glutaredoxin disulfide + H(2)O.
-!- SIMILARITY: Belongs to the ArsC family. {ECO:0000305}.
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EMBL; AL157959; CAM07558.1; -; Genomic_DNA.
RefSeq; WP_002225750.1; NC_003116.1.
ProteinModelPortal; P63621; -.
SMR; P63621; -.
EnsemblBacteria; CAM07558; CAM07558; NMA0252.
KEGG; nma:NMA0252; -.
HOGENOM; HOG000059717; -.
KO; K00537; -.
OMA; DYLKTPP; -.
Proteomes; UP000000626; Chromosome.
GO; GO:0008794; F:arsenate reductase (glutaredoxin) activity; IEA:UniProtKB-EC.
GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
CDD; cd03034; ArsC_ArsC; 1.
InterPro; IPR006659; Arsenate_reductase.
InterPro; IPR006660; Arsenate_reductase-like.
InterPro; IPR036249; Thioredoxin-like_sf.
Pfam; PF03960; ArsC; 1.
SUPFAM; SSF52833; SSF52833; 1.
TIGRFAMs; TIGR00014; arsC; 1.
PROSITE; PS51353; ARSC; 1.
3: Inferred from homology;
Arsenical resistance; Complete proteome; Oxidoreductase.
CHAIN 1 117 Putative arsenate reductase.
/FTId=PRO_0000162541.
SEQUENCE 117 AA; 12869 MW; C834075A7941EBE5 CRC64;
MPEIKIFHNP RCSKSRAALS LLEERGIAAE VVKYLDTPPD LSELKDIFNK LGLASARGMM
RVKDDLYKEL GLDNPNLDND ALLRAIADHP ALLERPIVLA NGKAAVGRPL ENIEAVL


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