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Putative arsenical resistance operon repressor ArsD

 ARSD_HALSA              Reviewed;         108 AA.
O52028;
14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
01-JUN-1998, sequence version 1.
07-JUN-2017, entry version 83.
RecName: Full=Putative arsenical resistance operon repressor ArsD;
Name=arsD; OrderedLocusNames=VNG_5181G;
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
(Halobacterium halobium).
Plasmid pNRC100.
Archaea; Euryarchaeota; Halobacteria; Halobacteriales;
Halobacteriaceae; Halobacterium.
NCBI_TaxID=64091;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
PubMed=9847077;
Ng W.V., Ciufo S.A., Smith T.M., Bumgarner R.E., Baskin D., Faust J.,
Hall B., Loretz C., Seto J., Slagel J., Hood L., DasSarma S.;
"Snapshot of a large dynamic replicon in a halophilic archaeon:
megaplasmid or minichromosome?";
Genome Res. 8:1131-1141(1998).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
PubMed=11016950; DOI=10.1073/pnas.190337797;
Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M.,
Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J.,
Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A.,
Leithauser B., Keller K., Cruz R., Danson M.J., Hough D.W.,
Maddocks D.G., Jablonski P.E., Krebs M.P., Angevine C.M., Dale H.,
Isenbarger T.A., Peck R.F., Pohlschroder M., Spudich J.L., Jung K.-H.,
Alam M., Freitas T., Hou S., Daniels C.J., Dennis P.P., Omer A.D.,
Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L., DasSarma S.;
"Genome sequence of Halobacterium species NRC-1.";
Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
[3]
INDUCTION, AND DISRUPTION PHENOTYPE.
STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
PubMed=15126481; DOI=10.1128/JB.186.10.3187-3194.2004;
Wang G., Kennedy S.P., Fasiludeen S., Rensing C., DasSarma S.;
"Arsenic resistance in Halobacterium sp. strain NRC-1 examined by
using an improved gene knockout system.";
J. Bacteriol. 186:3187-3194(2004).
-!- FUNCTION: Trans-acting repressor of the arsADRC operon.
{ECO:0000250}.
-!- INDUCTION: By arsenite and antimonite.
{ECO:0000269|PubMed:15126481}.
-!- DISRUPTION PHENOTYPE: Deletion of the arsADRC operon results in
increased sensitivity to arsenite and antimonite but not arsenate.
{ECO:0000269|PubMed:15126481}.
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EMBL; AF016485; AAC82908.1; -; Genomic_DNA.
PIR; T08341; T08341.
RefSeq; WP_010890457.1; NC_001869.1.
SMR; O52028; -.
EnsemblBacteria; AAC82908; AAC82908; AAC82908.
GeneID; 5954938; -.
KEGG; hal:arsD; -.
InParanoid; O52028; -.
OMA; LCCSTGV; -.
OrthoDB; POG093Z0H6M; -.
PhylomeDB; O52028; -.
Proteomes; UP000000554; Plasmid pNRC100.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
InterPro; IPR010712; Arsenical-R_ArsD.
Pfam; PF06953; ArsD; 1.
2: Evidence at transcript level;
Arsenical resistance; Complete proteome; DNA-binding; Plasmid;
Reference proteome; Repressor; Transcription;
Transcription regulation.
CHAIN 1 108 Putative arsenical resistance operon
repressor ArsD.
/FTId=PRO_0000429113.
SEQUENCE 108 AA; 12024 MW; 64C7441A6D03D4FA CRC64;
MTQLTLYEEA MCCSTGVCGP DPDDELVEVS AALDQLENEF DVDVSRANMQ HNIEQFLETQ
QIADLVEEHG PSILPITVVN DEIVARETYL SYDELASTFE DSPDPQEA


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