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Putative uncharacterized protein encoded by MIR7-3HG (Pituitary gland-specific factor 1)

 PGSF1_HUMAN             Reviewed;         128 AA.
Q8N6C7; D6W630; Q17RJ9; Q8N6C6;
05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
01-OCT-2002, sequence version 1.
05-JUL-2017, entry version 77.
RecName: Full=Putative uncharacterized protein encoded by MIR7-3HG;
AltName: Full=Pituitary gland-specific factor 1;
Name=MIR7-3HG; Synonyms=C19orf30, LINC00306, NCRNA00306, PGSF1;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), AND TISSUE SPECIFICITY.
TISSUE=Pituitary;
PubMed=11854097; DOI=10.1677/jme.0.0280033;
Tanaka S., Tatsumi K., Okubo K., Itoh K., Kawamoto S., Matsubara K.,
Amino N.;
"Expression profile of active genes in the human pituitary gland.";
J. Mol. Endocrinol. 28:33-44(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=15057824; DOI=10.1038/nature02399;
Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
Rubin E.M., Lucas S.M.;
"The DNA sequence and biology of human chromosome 19.";
Nature 428:529-535(2004).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), AND VARIANTS
SER-73 AND GLN-91.
TISSUE=Brain;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1; Synonyms=PGSF1a;
IsoId=Q8N6C7-1; Sequence=Displayed;
Name=2; Synonyms=PGSF1b;
IsoId=Q8N6C7-2; Sequence=VSP_014375, VSP_014376;
Note=May be produced at very low levels due to a premature stop
codon in the mRNA, leading to nonsense-mediated mRNA decay.;
-!- TISSUE SPECIFICITY: High expression in pituitary gland and weak in
pancreas. {ECO:0000269|PubMed:11854097}.
-!- CAUTION: Product of a dubious CDS prediction. May be a non-coding
RNA. {ECO:0000305}.
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EMBL; AB058892; BAB40233.2; -; mRNA.
EMBL; AB058893; BAB40234.2; -; mRNA.
EMBL; AC006537; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH471139; EAW69196.1; -; Genomic_DNA.
EMBL; CH471139; EAW69197.1; -; Genomic_DNA.
EMBL; BC117294; -; NOT_ANNOTATED_CDS; mRNA.
EMBL; BC117296; -; NOT_ANNOTATED_CDS; mRNA.
UniGene; Hs.326728; -.
PaxDb; Q8N6C7; -.
PRIDE; Q8N6C7; -.
DisGeNET; 284424; -.
GeneCards; MIR7-3HG; -.
H-InvDB; HIX0039937; -.
HGNC; HGNC:30049; MIR7-3HG.
neXtProt; NX_Q8N6C7; -.
eggNOG; ENOG410JHNV; Eukaryota.
eggNOG; ENOG4111DH4; LUCA.
InParanoid; Q8N6C7; -.
PRO; PR:Q8N6C7; -.
Proteomes; UP000005640; Unplaced.
CleanEx; HS_C19orf30; -.
5: Uncertain;
Alternative splicing; Complete proteome; Polymorphism;
Reference proteome.
CHAIN 1 128 Putative uncharacterized protein encoded
by MIR7-3HG.
/FTId=PRO_0000058365.
VAR_SEQ 83 91 LGMHSLHLH -> PPKVLGLQA (in isoform 2).
{ECO:0000303|PubMed:11854097}.
/FTId=VSP_014375.
VAR_SEQ 92 128 Missing (in isoform 2).
{ECO:0000303|PubMed:11854097}.
/FTId=VSP_014376.
VARIANT 73 73 R -> S (in dbSNP:rs11878617).
{ECO:0000269|PubMed:15489334}.
/FTId=VAR_030681.
VARIANT 91 91 H -> Q (in dbSNP:rs3760955).
{ECO:0000269|PubMed:15489334}.
/FTId=VAR_030682.
SEQUENCE 128 AA; 14321 MW; 7EAF4A1A025EE50A CRC64;
MPGMRLVCRL AHGHFPRKGQ RRRSLTVWKA ETSRADCLGA PNIRTAPLGR SEKRTAICFS
TGAQDSSQRA PFRLQNPGQL LQLGMHSLHL HPELPTTDPA FFCKLHFIKG NDPYCLTISH
VKSVLTFS


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