GENTAUR Molecular Products.

 H0ZPQ2_TAEGU            Unreviewed;       866 AA.
 H0ZPQ2;
 22-FEB-2012, integrated into UniProtKB/TrEMBL.
 22-FEB-2012, sequence version 1.
 16-JAN-2019, entry version 53.
 SubName: Full=RB transcriptional corepressor 1 {ECO:0000313|Ensembl:ENSTGUP00000012584};
 Name=RB1 {ECO:0000313|Ensembl:ENSTGUP00000012584};
 Taeniopygia guttata (Zebra finch) (Poephila guttata).
 Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
 Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
 Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea;
 Estrildidae; Estrildinae; Taeniopygia.
 NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000012584, ECO:0000313|Proteomes:UP000007754};
 [1] {ECO:0000313|Ensembl:ENSTGUP00000012584, ECO:0000313|Proteomes:UP000007754}
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
 PubMed=20360741; DOI=10.1038/nature08819;
 Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
 Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
 Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
 Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C.,
 London S.E., Li Y., Lin Y.C., George J., Sweedler J., Southey B.,
 Gunaratne P., Watson M., Nam K., Backstrom N., Smeds L., Nabholz B.,
 Itoh Y., Whitney O., Pfenning A.R., Howard J., Volker M.,
 Skinner B.M., Griffin D.K., Ye L., McLaren W.M., Flicek P.,
 Quesada V., Velasco G., Lopez-Otin C., Puente X.S., Olender T.,
 Lancet D., Smit A.F., Hubley R., Konkel M.K., Walker J.A.,
 Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z., Eichler E.E.,
 Stapley J., Slate J., Ekblom R., Birkhead T., Burke T., Burt D.,
 Scharff C., Adam I., Richard H., Sultan M., Soldatov A., Lehrach H.,
 Edwards S.V., Yang S.P., Li X., Graves T., Fulton L., Nelson J.,
 Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
 "The genome of a songbird.";
 Nature 464:757-762(2010).
 [2] {ECO:0000313|Ensembl:ENSTGUP00000012584}
 IDENTIFICATION.
 Ensembl;
 Submitted (JAN-2012) to UniProtKB.
 -----------------------------------------------------------------------
 Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
 Distributed under the Creative Commons Attribution (CC BY 4.0) License
 -----------------------------------------------------------------------
 EMBL; ABQF01007189; -; NOT_ANNOTATED_CDS; Genomic_DNA.
 EMBL; ABQF01007190; -; NOT_ANNOTATED_CDS; Genomic_DNA.
 EMBL; ABQF01007191; -; NOT_ANNOTATED_CDS; Genomic_DNA.
 STRING; 59729.ENSTGUP00000012584; -.
 Ensembl; ENSTGUT00000012723; ENSTGUP00000012584; ENSTGUG00000012205.
 eggNOG; KOG1010; Eukaryota.
 eggNOG; ENOG410XQF7; LUCA.
 GeneTree; ENSGT00940000155912; -.
 InParanoid; H0ZPQ2; -.
 OMA; EMQRTPR; -.
 TreeFam; TF105568; -.
 Reactome; R-TGU-113501; Inhibition of replication initiation of damaged DNA by RB1/E2F1.
 Reactome; R-TGU-2299718; Condensation of Prophase Chromosomes.
 Reactome; R-TGU-69231; Cyclin D associated events in G1.
 Proteomes; UP000007754; Chromosome 1.
 GO; GO:0008024; C:cyclin/CDK positive transcription elongation factor complex; IEA:Ensembl.
 GO; GO:0016605; C:PML body; IEA:Ensembl.
 GO; GO:0035189; C:Rb-E2F complex; IEA:Ensembl.
 GO; GO:0005819; C:spindle; IEA:Ensembl.
 GO; GO:0097718; F:disordered domain specific binding; IEA:Ensembl.
 GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
 GO; GO:0061676; F:importin-alpha family protein binding; IEA:Ensembl.
 GO; GO:0019900; F:kinase binding; IEA:Ensembl.
 GO; GO:0051219; F:phosphoprotein binding; IEA:Ensembl.
 GO; GO:0000987; F:proximal promoter sequence-specific DNA binding; IEA:Ensembl.
 GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IEA:Ensembl.
 GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
 GO; GO:0003180; P:aortic valve morphogenesis; IEA:Ensembl.
 GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
 GO; GO:0051301; P:cell division; IEA:Ensembl.
 GO; GO:0048667; P:cell morphogenesis involved in neuron differentiation; IEA:Ensembl.
 GO; GO:0071466; P:cellular response to xenobiotic stimulus; IEA:Ensembl.
 GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
 GO; GO:0043353; P:enucleate erythrocyte differentiation; IEA:Ensembl.
 GO; GO:0034349; P:glial cell apoptotic process; IEA:Ensembl.
 GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
 GO; GO:0034088; P:maintenance of mitotic sister chromatid cohesion; IEA:Ensembl.
 GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
 GO; GO:0120163; P:negative regulation of cold-induced thermogenesis; IEA:Ensembl.
 GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
 GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
 GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
 GO; GO:1904761; P:negative regulation of myofibroblast differentiation; IEA:Ensembl.
 GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
 GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
 GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
 GO; GO:0071930; P:negative regulation of transcription involved in G1/S transition of mitotic cell cycle; IEA:Ensembl.
 GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
 GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
 GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
 GO; GO:1904028; P:positive regulation of collagen fibril organization; IEA:Ensembl.
 GO; GO:0045651; P:positive regulation of macrophage differentiation; IEA:Ensembl.
 GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IEA:Ensembl.
 GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
 GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IEA:Ensembl.
 GO; GO:0071459; P:protein localization to chromosome, centromeric region; IEA:Ensembl.
 GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
 GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
 GO; GO:0071922; P:regulation of cohesin loading; IEA:Ensembl.
 GO; GO:0043550; P:regulation of lipid kinase activity; IEA:Ensembl.
 GO; GO:0031134; P:sister chromatid biorientation; IEA:Ensembl.
 GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
 GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
 GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
 InterPro; IPR013763; Cyclin-like.
 InterPro; IPR036915; Cyclin-like_sf.
 InterPro; IPR033057; RB1.
 InterPro; IPR002720; RB_A.
 InterPro; IPR002719; RB_B.
 InterPro; IPR015030; RB_C.
 InterPro; IPR028309; RB_fam.
 InterPro; IPR024599; RB_N.
 PANTHER; PTHR13742; PTHR13742; 1.
 PANTHER; PTHR13742:SF17; PTHR13742:SF17; 1.
 Pfam; PF11934; DUF3452; 1.
 Pfam; PF01858; RB_A; 1.
 Pfam; PF01857; RB_B; 1.
 Pfam; PF08934; Rb_C; 1.
 SMART; SM00385; CYCLIN; 1.
 SMART; SM01367; DUF3452; 1.
 SMART; SM01368; RB_A; 1.
 SMART; SM01369; Rb_C; 1.
 SUPFAM; SSF47954; SSF47954; 2.
 4: Predicted;
 Complete proteome {ECO:0000313|Proteomes:UP000007754};
 Reference proteome {ECO:0000313|Proteomes:UP000007754}.
 DOMAIN       21    173       DUF3452. {ECO:0000259|SMART:SM01367}.
 DOMAIN      319    521       RB_A. {ECO:0000259|SMART:SM01368}.
 DOMAIN      608    709       CYCLIN. {ECO:0000259|SMART:SM00385}.
 DOMAIN      716    866       Rb_C. {ECO:0000259|SMART:SM01369}.
 SEQUENCE   866 AA;  99226 MW;  58956262CBB26CE6 CRC64;
 CDALKVSESV RERAWKTYES LSAADGALAC NTKKKETWGV CIFIVAIDLD EVTFTFTELL
 KSINMSVCTF FQFLKEVDVN MDTVSTKVDS TVSRLKKKYD VLFALYHKFE RTCGLIYLEQ
 PSSEISAELS SILVLKNYWI TFLLAKGKVL QVEDDLVISF QLLLCVLDYF IKLSPPAMLK
 EPYKSSVSAV TVNGSARTPR RGQNRSSRTA KQLDTDTKII EILCKEHDCN LDEVKNVYFT
 SFIPFLNSAS ILASNGLPEV EVILKQYDEL YVKNKDIDAR LFLNHDETLQ PDVRACSQLE
 RTPVKNNPDE EINIILPQTP VRAAMNNIQQ LIMILNSATD KPSDTLIKYF NNCTVNPKDS
 ILKRVESFDH IFKKKFAEAV GQGWAETGSQ RYKLGVRLYY RVMESMLKSE EERLSVQNFS
 KLLNDNIFHT SLLACALEVV MATYGRNASQ SDNTSAETDL SFPWILNVFD LKAFDFYKVI
 ESFIRAEPSL TREMIKHLEH CEHRIMESLA WQSGSPLFDR IKESKEREGQ TDQPEPTSTP
 NMPFQHNHTA ADLYLSPVKS PKKKASGPPL SATSPPDAQP AVTPQTQKVQ KSTSLSLFYK
 KVYLLAYRRL HTLFLHLLSE HPELEPLIWT LFQHTLQNEY ELMRDRHLDQ IMMCSMYGIC
 KVKNVDLQFK MIVSAYKELC NTNQETFKRV LIREEKYDSI IVFYNLVFMQ KLKTNILQYA
 SSRPPTLSPI PHIPRSPYQF SNSPRRVPAG NNIYISPLKS PYKFSDGFQS PTKMTPRSRI
 LVSIGESFGT YEKFQKINQM MCNSEYQLKR CAEAGAAAPK PLKRLRFDIE GTDEADGSKH
 LPQESKFQQK LAERTSTRTR MQKQKL

Related products :