Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Ras-like protein 1

 RAS1_DROVI              Reviewed;         189 AA.
B4LY29;
10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
23-SEP-2008, sequence version 1.
23-MAY-2018, entry version 65.
RecName: Full=Ras-like protein 1 {ECO:0000250|UniProtKB:P08646};
Flags: Precursor;
Name=Ras85D {ECO:0000250|UniProtKB:P08646};
Synonyms=Ras1 {ECO:0000312|FlyBase:FBgn0085906}; ORFNames=GJ23844;
Drosophila virilis (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila.
NCBI_TaxID=7244;
[1] {ECO:0000312|EMBL:EDW66895.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Tucson 15010-1051.87 {ECO:0000312|EMBL:EDW66895.1};
PubMed=17994087; DOI=10.1038/nature06341;
Drosophila 12 genomes consortium;
"Evolution of genes and genomes on the Drosophila phylogeny.";
Nature 450:203-218(2007).
-!- FUNCTION: Ras proteins bind GDP/GTP and possess intrinsic GTPase
activity. Plays a role in eye development by regulating cell
growth, survival of postmitotic ommatidial cells and
differentiation of photoreceptor cells. During larval development,
mediates Ptth/tor signaling leading to the production of ecdysone,
an hormone required for the initiation of metamorphosis.
{ECO:0000250|UniProtKB:P01112, ECO:0000250|UniProtKB:P08646}.
-!- ENZYME REGULATION: Alternates between an inactive form bound to
GDP and an active form bound to GTP. Activated by a guanine
nucleotide-exchange factor (GEF) and inactivated by a GTPase-
activating protein (GAP).
-!- SUBCELLULAR LOCATION: Cell membrane
{ECO:0000250|UniProtKB:P08646}; Lipid-anchor
{ECO:0000250|UniProtKB:P08646}; Cytoplasmic side
{ECO:0000250|UniProtKB:P08646}.
-!- SIMILARITY: Belongs to the small GTPase superfamily. Ras family.
{ECO:0000255}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; CH940650; EDW66895.1; -; Genomic_DNA.
RefSeq; XP_002053375.1; XM_002053339.2.
RefSeq; XP_015027424.1; XM_015171938.1.
ProteinModelPortal; B4LY29; -.
SMR; B4LY29; -.
STRING; 7244.FBpp0238261; -.
PRIDE; B4LY29; -.
EnsemblMetazoa; FBtr0239769; FBpp0238261; FBgn0085906.
EnsemblMetazoa; FBtr0435777; FBpp0392722; FBgn0085906.
GeneID; 6629799; -.
KEGG; dvi:Dvir_GJ23844; -.
FlyBase; FBgn0085906; Dvir\Ras1.
eggNOG; KOG0395; Eukaryota.
eggNOG; COG1100; LUCA.
InParanoid; B4LY29; -.
KO; K07827; -.
OMA; QSWAVNM; -.
OrthoDB; EOG091G0UAU; -.
PhylomeDB; B4LY29; -.
ChiTaRS; Ras85D; fly.
Proteomes; UP000008792; Unassembled WGS sequence.
Bgee; FBgn0085906; -.
GO; GO:0005622; C:intracellular; IEA:GOC.
GO; GO:0016020; C:membrane; ISS:UniProtKB.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO; GO:0003924; F:GTPase activity; IEA:EnsemblMetazoa.
GO; GO:0007298; P:border follicle cell migration; IEA:EnsemblMetazoa.
GO; GO:0001709; P:cell fate determination; IEA:EnsemblMetazoa.
GO; GO:0009267; P:cellular response to starvation; IEA:EnsemblMetazoa.
GO; GO:0030381; P:chorion-containing eggshell pattern formation; IEA:EnsemblMetazoa.
GO; GO:0048749; P:compound eye development; IEA:EnsemblMetazoa.
GO; GO:0051607; P:defense response to virus; IEA:EnsemblMetazoa.
GO; GO:0008340; P:determination of adult lifespan; IEA:EnsemblMetazoa.
GO; GO:0007395; P:dorsal closure, spreading of leading edge cells; IEA:EnsemblMetazoa.
GO; GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IEA:EnsemblMetazoa.
GO; GO:0007455; P:eye-antennal disc morphogenesis; IEA:EnsemblMetazoa.
GO; GO:0007369; P:gastrulation; IEA:EnsemblMetazoa.
GO; GO:0035099; P:hemocyte migration; IEA:EnsemblMetazoa.
GO; GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IEA:EnsemblMetazoa.
GO; GO:0002168; P:instar larval development; IEA:EnsemblMetazoa.
GO; GO:0036335; P:intestinal stem cell homeostasis; IEA:EnsemblMetazoa.
GO; GO:0072002; P:Malpighian tubule development; IEA:EnsemblMetazoa.
GO; GO:0000165; P:MAPK cascade; IEA:EnsemblMetazoa.
GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:EnsemblMetazoa.
GO; GO:0046673; P:negative regulation of compound eye retinal cell programmed cell death; IEA:EnsemblMetazoa.
GO; GO:0010629; P:negative regulation of gene expression; IEA:EnsemblMetazoa.
GO; GO:0016242; P:negative regulation of macroautophagy; IEA:EnsemblMetazoa.
GO; GO:0007309; P:oocyte axis specification; IEA:EnsemblMetazoa.
GO; GO:0007422; P:peripheral nervous system development; IEA:EnsemblMetazoa.
GO; GO:0008594; P:photoreceptor cell morphogenesis; IEA:EnsemblMetazoa.
GO; GO:0045793; P:positive regulation of cell size; IEA:EnsemblMetazoa.
GO; GO:0035208; P:positive regulation of hemocyte proliferation; IEA:EnsemblMetazoa.
GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:EnsemblMetazoa.
GO; GO:0046534; P:positive regulation of photoreceptor cell differentiation; IEA:EnsemblMetazoa.
GO; GO:0006606; P:protein import into nucleus; IEA:EnsemblMetazoa.
GO; GO:0007265; P:Ras protein signal transduction; IEA:EnsemblMetazoa.
GO; GO:0045610; P:regulation of hemocyte differentiation; IEA:EnsemblMetazoa.
GO; GO:0040014; P:regulation of multicellular organism growth; IEA:EnsemblMetazoa.
GO; GO:0048865; P:stem cell fate commitment; IEA:EnsemblMetazoa.
GO; GO:0072089; P:stem cell proliferation; IEA:EnsemblMetazoa.
GO; GO:0038202; P:TORC1 signaling; IEA:EnsemblMetazoa.
GO; GO:0060438; P:trachea development; IEA:EnsemblMetazoa.
GO; GO:0007426; P:tracheal outgrowth, open tracheal system; IEA:EnsemblMetazoa.
InterPro; IPR027417; P-loop_NTPase.
InterPro; IPR005225; Small_GTP-bd_dom.
InterPro; IPR001806; Small_GTPase.
InterPro; IPR020849; Small_GTPase_Ras-type.
PANTHER; PTHR24070; PTHR24070; 1.
Pfam; PF00071; Ras; 1.
SUPFAM; SSF52540; SSF52540; 1.
TIGRFAMs; TIGR00231; small_GTP; 1.
PROSITE; PS51421; RAS; 1.
3: Inferred from homology;
Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane;
Methylation; Nucleotide-binding; Prenylation; Reference proteome.
CHAIN 1 186 Ras-like protein 1.
{ECO:0000250|UniProtKB:P08646}.
/FTId=PRO_0000363718.
PROPEP 187 189 Removed in mature form.
{ECO:0000250|UniProtKB:P08646}.
/FTId=PRO_0000363719.
NP_BIND 10 17 GTP. {ECO:0000250|UniProtKB:P01112}.
NP_BIND 57 61 GTP. {ECO:0000250|UniProtKB:P01112}.
NP_BIND 116 119 GTP. {ECO:0000250|UniProtKB:P01112}.
MOTIF 32 40 Effector region.
MOD_RES 186 186 Cysteine methyl ester.
{ECO:0000250|UniProtKB:P08646}.
LIPID 186 186 S-geranylgeranyl cysteine.
{ECO:0000250|UniProtKB:P08646}.
SEQUENCE 189 AA; 21550 MW; 14048F4FEAD7CCCD CRC64;
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG
QEEYSAMRDQ YMRTGEGFLL VFAVNSAKSF EDIGTYREQI KRVKDAEEVP MVLVGNKCDL
ASWNVQNEQA REVAKQYGIP YIETSAKTRM GVDDAFYTLV REIRKDKDNK GRKGRKTNKP
NRRFKCKML


Related products :

Catalog number Product name Quantity
PAH-G1-2 Protein Arrays containing 234 Human Protein for simultaneous detection of Protein function, including Protein-protein interaction, Protein modification, antibody specificity, auto-antibody and small m 1 glass slide with 2 sub-arrays
29-844 RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the 0.1 mg
29-850 The protein contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions.The protein encoded by this 0.1 mg
EIAAB10617 DCN1-like protein 1,DCUN1 domain-containing protein 1,Dcun1d1,Dcun1l1,Defective in cullin neddylation protein 1-like protein 1,Mouse,Mus musculus,Rp42,Tes3,Testis-specific protein 3
EIAAB44668 Dap12,DNAX-activation protein 12,Karap,KAR-associated protein,Killer-activating receptor-associated protein,Mouse,Mus musculus,TYRO protein tyrosine kinase-binding protein,Tyrobp
EIAAB44667 DAP12,DNAX-activation protein 12,Homo sapiens,Human,KARAP,KAR-associated protein,Killer-activating receptor-associated protein,TYRO protein tyrosine kinase-binding protein,TYROBP
18-003-43520 HSPB1-associated protein 1 - 27 KdA heat shock protein-associated protein 1; Protein associated with small stress protein 1 Polyclonal 0.05 mg Aff Pur
EIAAB25665 AML1T1,CBFA2T1,CDR,Cyclin-D-related protein,Eight twenty one protein,ETO,Homo sapiens,Human,MTG8,Protein CBFA2T1,Protein ETO,Protein MTG8,RUNX1T1,Zinc finger MYND domain-containing protein 2,ZMYND2
EIAAB46018 C6orf55,Dopamine-responsive gene 1 protein,DRG-1,Homo sapiens,HSPC228,Human,LIP5,LYST-interacting protein 5,My012,SBP1,SKD1-binding protein 1,Vacuolar protein sorting-associated protein VTA1 homolog,V
18-003-43690 Guanine nucleotide-binding protein subunit beta-like protein 1 - G protein subunit beta-like protein 1; WD40 repeat-containing protein deleted in VCFS; Protein WDVCF; WD repeat-containing protein 14; 0.1 mg Protein A
EIAAB32247 ADP-ribosylation factor-like protein 6-interacting protein 5,Aip-5,ARL-6-interacting protein 5,ARL6IP5,Cytoskeleton-related vitamin A-responsive protein,Dermal papilla-derived protein 11,DERP11,Glutam
E1773h ELISA kit G-CSF-induced gene 1 protein,GIG1,GIG-1 protein,GMP-17,Granule membrane protein of 17 kDa,Homo sapiens,Human,Natural killer cell protein 7,NKG7,p15-TIA-1,Protein NKG7 96T
U1773h CLIA G-CSF-induced gene 1 protein,GIG1,GIG-1 protein,GMP-17,Granule membrane protein of 17 kDa,Homo sapiens,Human,Natural killer cell protein 7,NKG7,p15-TIA-1,Protein NKG7 96T
E1773h ELISA G-CSF-induced gene 1 protein,GIG1,GIG-1 protein,GMP-17,Granule membrane protein of 17 kDa,Homo sapiens,Human,Natural killer cell protein 7,NKG7,p15-TIA-1,Protein NKG7 96T
EIAAB31034 Androgen receptor-interacting protein 3,ARIP3,DAB2-interacting protein,DIP,E3 SUMO-protein ligase PIAS2,Homo sapiens,Human,Miz1,Msx-interacting zinc finger protein,PIAS2,PIAS-NY protein,PIASX,Protein
EIAAB29586 Mouse,Mus musculus,p53-induced gene 11 protein,Pig11,Tp53i11,Transformation related protein 53 inducible protein 11,Trp53i11,Tumor protein p53-inducible protein 11
EIAAB43486 Mouse,Mus musculus,Protein TAP1,Protein TRUSS,Rabex-5_Rin2-interacting protein,Short transient receptor potential channel 4-associated protein,TNF-receptor ubiquitous scaffolding_signaling protein,Trp
10-663-45493 Heat Shock Protein 22kD (HSP22) Human - HspB8; Alpha crystallin C chain; Small stress protein-like protein HSP22; E2-induced gene 1 protein; Protein kinase H11 N_A 0.002 mg
10-663-45493 Heat Shock Protein 22kD (HSP22) Human - HspB8; Alpha crystallin C chain; Small stress protein-like protein HSP22; E2-induced gene 1 protein; Protein kinase H11 N_A 0.01 mg
10-663-45493 Heat Shock Protein 22kD (HSP22) Human - HspB8; Alpha crystallin C chain; Small stress protein-like protein HSP22; E2-induced gene 1 protein; Protein kinase H11 N_A 0.1 mg
EIAAB43485 C20orf188,Homo sapiens,Human,Protein TAP1,Protein TRUSS,Short transient receptor potential channel 4-associated protein,TNF-receptor ubiquitous scaffolding_signaling protein,Trp4-associated protein,TR
EIAAB33912 E3 ubiquitin-protein ligase RBBP6,Mouse,Mus musculus,P2pr,p53-associated cellular protein of testis,Pact,Proliferation potential-related protein,Protein P2P-R,Rbbp6,Retinoblastoma-binding protein 6
EIAAB38162 Homo sapiens,Human,MAP,Merlin-associated protein,RabGAPLP,RABGAPLP,Rab-GTPase-activating protein-like protein,RUN and TBC1 domain-containing protein 3,RUTBC3,SGSM3,Small G protein signaling modulator
EIAAB29908 Cap1,Contraception-associated protein 1,Fertility protein SP22,Park7,Parkinson disease protein 7 homolog,Protein CAP1,Protein DJ-1,Rat,Rattus norvegicus
EIAAB31031 DDXBP1,DEAD_H box-binding protein 1,E3 SUMO-protein ligase PIAS1,GBP,Gu-binding protein,Homo sapiens,Human,PIAS1,Protein inhibitor of activated STAT protein 1,RNA helicase II-binding protein


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur