Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Receptor binding protein (RBP) (Gene product 18) (Gp18)

 RBP_BPLP2               Reviewed;         264 AA.
Q71AW2; Q1RNF7;
02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
05-JUL-2004, sequence version 1.
22-NOV-2017, entry version 82.
RecName: Full=Receptor binding protein {ECO:0000303|PubMed:20351260};
Short=RBP {ECO:0000303|PubMed:20351260};
AltName: Full=Gene product 18 {ECO:0000305};
Short=Gp18 {ECO:0000305};
Name=rbp {ECO:0000312|EMBL:AAQ10938.1};
Lactococcus phage p2 (Lactococcus lactis bacteriophage p2).
Viruses; dsDNA viruses, no RNA stage; Caudovirales; Siphoviridae;
Sk1virus.
NCBI_TaxID=254252;
NCBI_TaxID=1358; Lactococcus lactis.
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=15466519; DOI=10.1128/AEM.70.10.5818-5824.2004;
Dupont K., Vogensen F.K., Neve H., Bresciani J., Josephsen J.;
"Identification of the receptor-binding protein in 936-species
lactococcal bacteriophages.";
Appl. Environ. Microbiol. 70:5818-5824(2004).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=15752347; DOI=10.1111/j.1365-2672.2005.02548.x;
Dupont K., Vogensen F.K., Josephsen J.;
"Detection of lactococcal 936-species bacteriophages in whey by
magnetic capture hybridization PCR targeting a variable region of
receptor-binding protein genes.";
J. Appl. Microbiol. 98:1001-1009(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Tremblay D.M., Deveau H., Moineau S.;
"Complete genomic sequence of Lactococcus lactis phage p2.";
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000244|PDB:1ZRU}
X-RAY CRYSTALLOGRAPHY (1.73 ANGSTROMS), AND INTERACTION WITH HOST
PHOSPHOPOLYSACCHARIDES.
PubMed=16547026; DOI=10.1128/JB.188.7.2400-2410.2006;
Tremblay D.M., Tegoni M., Spinelli S., Campanacci V., Blangy S.,
Huyghe C., Desmyter A., Labrie S., Moineau S., Cambillau C.;
"Receptor-binding protein of Lactococcus lactis phages: identification
and characterization of the saccharide receptor-binding site.";
J. Bacteriol. 188:2400-2410(2006).
[5] {ECO:0000244|PDB:2BSD, ECO:0000244|PDB:2BSE}
X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).
PubMed=16327804; DOI=10.1038/nsmb1029;
Spinelli S., Desmyter A., Verrips C.T., de Haard H.J., Moineau S.,
Cambillau C.;
"Lactococcal bacteriophage p2 receptor-binding protein structure
suggests a common ancestor gene with bacterial and mammalian
viruses.";
Nat. Struct. Mol. Biol. 13:85-89(2006).
[6] {ECO:0000244|PDB:2WZP, ECO:0000244|PDB:2X53}
X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 2-264, SUBUNIT, SUBCELLULAR
LOCATION, INTERACTION WITH HOST PHOSPHOPOLYSACCHARIDES, AND FUNCTION.
PubMed=20351260; DOI=10.1073/pnas.1000232107;
Sciara G., Bebeacua C., Bron P., Tremblay D., Ortiz-Lombardia M.,
Lichiere J., van Heel M., Campanacci V., Moineau S., Cambillau C.;
"Structure of lactococcal phage p2 baseplate and its mechanism of
activation.";
Proc. Natl. Acad. Sci. U.S.A. 107:6852-6857(2010).
[7]
STRUCTURE BY ELECTRON MICROSCOPY (22 ANGSTROMS) OF THE TAIL, FUNCTION,
SUBUNIT, SUBCELLULAR LOCATION, DOMAIN, INTERACTION WITH HOST
PHOSPHOPOLYSACCHARIDES, AND INTERACTION WITH THE DISTAL TAIL PROTEIN.
PubMed=24027307; DOI=10.1128/JVI.02033-13;
Bebeacua C., Tremblay D., Farenc C., Chapot-Chartier M.P.,
Sadovskaya I., van Heel M., Veesler D., Moineau S., Cambillau C.;
"Structure, adsorption to host, and infection mechanism of virulent
lactococcal phage p2.";
J. Virol. 87:12302-12312(2013).
-!- FUNCTION: Binds to the host phosphopolysaccharides at the onset of
infection. Upon activation by calcium, the receptor binding
proteins change their conformation, presenting their binding sites
to the host, and a channel opens at the bottom of the baseplate
for DNA ejection. {ECO:0000269|PubMed:20351260,
ECO:0000269|PubMed:24027307}.
-!- SUBUNIT: Homotrimer; found as an assembly of 6 homotrimers
(PubMed:20351260, PubMed:24027307). Interacts with host
phosphopolysaccharides; this allows the virus to bind the external
cell wall layer (PubMed:16547026, PubMed:20351260,
PubMed:24027307). Interacts with the distal tail protein
(PubMed:24027307). {ECO:0000269|PubMed:20351260,
ECO:0000269|PubMed:24027307}.
-!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:20351260,
ECO:0000269|PubMed:24027307}. Note=Part of the baseplate.
{ECO:0000269|PubMed:20351260, ECO:0000269|PubMed:24027307}.
-!- DOMAIN: The C-terminus is involved in host receptor binding. Host-
recognition domains point upwards, towards the capsid.
{ECO:0000269|PubMed:24027307}.
-!- SIMILARITY: Belongs to the skunalikevirus receptor binding protein
family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AF539441; AAQ10938.1; -; Genomic_DNA.
EMBL; GQ979703; AAT81478.1; -; Genomic_DNA.
PDB; 1ZRU; X-ray; 1.73 A; A/B/C=1-264.
PDB; 2BSD; X-ray; 2.30 A; A/B/C=1-264.
PDB; 2BSE; X-ray; 2.70 A; A/B/C=1-264.
PDB; 2WZP; X-ray; 2.60 A; A/B/C/G/H/I=2-264.
PDB; 2X53; X-ray; 3.90 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R=2-264.
PDB; 3DA0; X-ray; 1.65 A; A/B/C=163-264.
PDB; 4V5I; X-ray; 5.46 A; AA/AB/AC/AD/AE/AF/AG/AH/AI/AJ/AK/AL/AM/AN/AO/AP/AQ/AR/BA/BB/BC/BD/BE/BF/BG/BH/BI/BJ/BK/BL=2-264.
PDBsum; 1ZRU; -.
PDBsum; 2BSD; -.
PDBsum; 2BSE; -.
PDBsum; 2WZP; -.
PDBsum; 2X53; -.
PDBsum; 3DA0; -.
PDBsum; 4V5I; -.
ProteinModelPortal; Q71AW2; -.
SMR; Q71AW2; -.
DIP; DIP-59525N; -.
IntAct; Q71AW2; 1.
EvolutionaryTrace; Q71AW2; -.
Proteomes; UP000002348; Genome.
GO; GO:0098025; C:virus tail, baseplate; IDA:UniProtKB.
GO; GO:0007155; P:cell adhesion; IEA:InterPro.
GO; GO:0098670; P:entry receptor-mediated virion attachment to host cell; IEA:UniProtKB-KW.
GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
GO; GO:0019062; P:virion attachment to host cell; IDA:UniProtKB.
InterPro; IPR008982; Adenovirus_pIV-like_att.
InterPro; IPR015027; Caudo_bapla_RBP.
Pfam; PF08931; Caudo_bapla_RBP; 1.
SUPFAM; SSF49835; SSF49835; 1.
1: Evidence at protein level;
3D-structure; Complete proteome; Host-virus interaction;
Viral attachment to host cell;
Viral attachment to host entry receptor; Viral baseplate protein;
Viral tail protein; Virion; Virus entry into host cell.
CHAIN 1 264 Receptor binding protein.
/FTId=PRO_0000438236.
REGION 164 264 Host receptor binding.
{ECO:0000269|PubMed:20351260}.
STRAND 3 5 {ECO:0000244|PDB:1ZRU}.
STRAND 7 9 {ECO:0000244|PDB:2WZP}.
HELIX 20 31 {ECO:0000244|PDB:1ZRU}.
STRAND 39 44 {ECO:0000244|PDB:1ZRU}.
STRAND 47 49 {ECO:0000244|PDB:2BSD}.
STRAND 50 62 {ECO:0000244|PDB:1ZRU}.
STRAND 65 75 {ECO:0000244|PDB:1ZRU}.
STRAND 80 88 {ECO:0000244|PDB:1ZRU}.
STRAND 97 104 {ECO:0000244|PDB:1ZRU}.
TURN 112 114 {ECO:0000244|PDB:1ZRU}.
STRAND 119 128 {ECO:0000244|PDB:1ZRU}.
STRAND 130 138 {ECO:0000244|PDB:1ZRU}.
STRAND 142 144 {ECO:0000244|PDB:1ZRU}.
STRAND 146 157 {ECO:0000244|PDB:1ZRU}.
STRAND 163 171 {ECO:0000244|PDB:3DA0}.
STRAND 174 181 {ECO:0000244|PDB:3DA0}.
TURN 182 184 {ECO:0000244|PDB:3DA0}.
STRAND 185 194 {ECO:0000244|PDB:3DA0}.
HELIX 210 212 {ECO:0000244|PDB:3DA0}.
STRAND 218 224 {ECO:0000244|PDB:3DA0}.
STRAND 230 235 {ECO:0000244|PDB:3DA0}.
STRAND 241 243 {ECO:0000244|PDB:3DA0}.
STRAND 253 262 {ECO:0000244|PDB:3DA0}.
SEQUENCE 264 AA; 28645 MW; 6D2F7356D7C34853 CRC64;
MTIKNFTFFS PNSTEFPVGS NNDGKLYMML TGMDYRTIRR KDWSSPLNTA LNVQYTNTSI
IAGGRYFELL NETVALKGDS VNYIHANIDL TQTANPVSLS AETANNSNGV DINNGSGVLK
VCFDIVTTSG TGVTSTKPIV QTSTLDSISV NDMTVSGSID VPVQTLTVEA GNGLQLQLTK
KNNDLVIVRF FGSVSNIQKG WNMSGTWVDR PFRPAAVQSL VGHFAGRDTS FHIDINPNGS
ITWWGANIDK TPIATRGNGS YFIK


Related products :

Catalog number Product name Quantity
U0449r CLIA Ebag9,Estrogen receptor-binding fragment-associated gene 9 protein,Rat,Rattus norvegicus,Receptor-binding cancer antigen expressed on SiSo cells 96T
E0449r ELISA kit Ebag9,Estrogen receptor-binding fragment-associated gene 9 protein,Rat,Rattus norvegicus,Receptor-binding cancer antigen expressed on SiSo cells 96T
E0449r ELISA Ebag9,Estrogen receptor-binding fragment-associated gene 9 protein,Rat,Rattus norvegicus,Receptor-binding cancer antigen expressed on SiSo cells 96T
27-386 ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding 0.1 mg
27-385 ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding 0.05 mg
DBNDD1 DBI Gene diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
SCH-MCA4750 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format S_N, Isotypes IgG1, Applications IF, 0.1 ml
MCA4750 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format S_N, Isotypes IgG1, Applications IF, 0.1 ml
MCA2084 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format S_N, Isotypes IgG2b, Applications C, 1 ml
SCH-MCA2084 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format S_N, Isotypes IgG2b, Applications C, 1 ml
7863-1004 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications 0.2 mg
SCH-7863-1004 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, Applications 0.2 mg
SCH-7863-2004 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format Purified, Isotypes IgG2a, Applications 0.2 ml
7863-2004 MOUSE ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Monoclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Mouse, Format Purified, Isotypes IgG2a, Applications 0.2 ml
30-430 METTL1 contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a con 0.1 mg
29-264 RBM9 is a RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding prot 0.05 mg
E0449m ELISA Cancer-associated surface antigen RCAS1,Ebag9,Estrogen receptor-binding fragment-associated gene 9 protein,Mouse,Mus musculus,Rcas1,Receptor-binding cancer antigen expressed on SiSo cells 96T
E0449m ELISA kit Cancer-associated surface antigen RCAS1,Ebag9,Estrogen receptor-binding fragment-associated gene 9 protein,Mouse,Mus musculus,Rcas1,Receptor-binding cancer antigen expressed on SiSo cells 96T
U0449m CLIA Cancer-associated surface antigen RCAS1,Ebag9,Estrogen receptor-binding fragment-associated gene 9 protein,Mouse,Mus musculus,Rcas1,Receptor-binding cancer antigen expressed on SiSo cells 96T
E0449h ELISA kit Cancer-associated surface antigen RCAS1,EBAG9,Estrogen receptor-binding fragment-associated gene 9 protein,Homo sapiens,Human,RCAS1,Receptor-binding cancer antigen expressed on SiSo cells 96T
U0449h CLIA Cancer-associated surface antigen RCAS1,EBAG9,Estrogen receptor-binding fragment-associated gene 9 protein,Homo sapiens,Human,RCAS1,Receptor-binding cancer antigen expressed on SiSo cells 96T
E0449h ELISA Cancer-associated surface antigen RCAS1,EBAG9,Estrogen receptor-binding fragment-associated gene 9 protein,Homo sapiens,Human,RCAS1,Receptor-binding cancer antigen expressed on SiSo cells 96T
SCH-7863-0504 RABBIT ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Polyclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Rabbit, Format Serum, Isotypes Polyclonal IgG, Appl 50 µl
7863-0504 RABBIT ANTI HUMAN PROTEIN GENE PRODUCT 9.5, Product Type Polyclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5, Target Species Human, Host Rabbit, Format Serum, Isotypes Polyclonal IgG, Appl 50 µl
AHP739 GOAT ANTI HUMAN PROTEIN GENE PRODUCT 9.5 (N_TERMINAL), Product Type Polyclonal Antibody, Specificity PROTEIN GENE PRODUCT 9.5 , Target Species Human, Host Goat, Format Serum, Isotypes Polyclonal 0.1 ml


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur