Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) (RNA-directed RNA polymerase) [Cleaved into: Replicase small subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 3.6.4.13) (126 kDa protein) (Methyltransferase/RNA helicase) (MT/HEL)]

 RDRP_TOML               Reviewed;        1616 AA.
P03587; O41352;
21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
01-DEC-2000, sequence version 2.
12-APR-2017, entry version 90.
RecName: Full=Replicase large subunit;
EC=2.1.1.-;
EC=2.7.7.-;
EC=2.7.7.48;
EC=3.6.4.13;
AltName: Full=183 kDa protein;
AltName: Full=RNA-directed RNA polymerase;
Contains:
RecName: Full=Replicase small subunit;
EC=2.1.1.-;
EC=2.7.7.-;
EC=3.6.4.13;
AltName: Full=126 kDa protein;
AltName: Full=Methyltransferase/RNA helicase;
Short=MT/HEL;
Tomato mosaic virus (strain L) (ToMV) (TMV strain tomato).
Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage;
Virgaviridae; Tobamovirus.
NCBI_TaxID=12252;
NCBI_TaxID=4151; Antirrhinum majus (Garden snapdragon).
NCBI_TaxID=4071; Capsicum (peppers).
NCBI_TaxID=46246; Delphinium.
NCBI_TaxID=4101; Petunia.
NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
NCBI_TaxID=13707; Tagetes (marigolds).
[1]
NUCLEOTIDE SEQUENCE [GENOMIC RNA].
PubMed=6549393;
Ohno T., Aoyagi M., Yamanashi Y., Saito H., Ikawa S., Meshi T.,
Okada Y.;
"Nucleotide sequence of the tobacco mosaic virus (tomato strain)
genome and comparison with the common strain genome.";
J. Biochem. 96:1915-1923(1984).
[2]
FUNCTION, AND MUTAGENESIS OF CYS-349.
PubMed=14512550; DOI=10.1128/JVI.77.20.11016-11026.2003;
Kubota K., Tsuda S., Tamai A., Meshi T.;
"Tomato mosaic virus replication protein suppresses virus-targeted
posttranscriptional gene silencing.";
J. Virol. 77:11016-11026(2003).
[3]
X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 666-1111, AND INTERACTION
WITH HOST PROTEINS TOM1 AND ARL8.
PubMed=22573863; DOI=10.1128/JVI.00118-12;
Nishikiori M., Sugiyama S., Xiang H., Niiyama M., Ishibashi K.,
Inoue T., Ishikawa M., Matsumura H., Katoh E.;
"Crystal structure of the superfamily 1 helicase from Tomato mosaic
virus.";
J. Virol. 86:7565-7576(2012).
-!- FUNCTION: Replicase large subunit: is an RNA-dependent RNA
polymerase active in viral RNA replication.
{ECO:0000269|PubMed:14512550}.
-!- FUNCTION: Replicase small subunit: is a methyltransferase active
in RNA capping and an RNA helicase. Methyltransferase displays a
cytoplasmic capping enzyme activity. This function is necessary
since all viral RNAs are synthesized in the cytoplasm, and host
capping enzymes are restricted to the nucleus. Helicase region
probably exhibits NTPase and RNA unwinding activities (Potential).
It also acts as a suppressor of RNA-mediated gene silencing, also
known as post-transcriptional gene silencing (PTGS), a mechanism
of plant viral defense that limits the accumulation of viral RNAs.
May mediate silencing suppression through either inhibition of
HEN1-mediated siRNA or siRNA demethylation (By similarity).
{ECO:0000250, ECO:0000305}.
-!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate
+ RNA(n+1). {ECO:0000255|PROSITE-ProRule:PRU00539}.
-!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
-!- SUBUNIT: Heterodimer of a large and a small subunit (By
similarity). May interact with the host proteins TOM1 and ARL8.
{ECO:0000250}.
-!- MISCELLANEOUS: This protein is translated as a fusion protein by
episodic readthrough of a termination codon. When readthrough of
the terminator codon TGA occurs between the codons for Gln-1116
and Gln-1118, this results in the addition of the RdRp region to
the replicase.
-!- SIMILARITY: Belongs to the ssRNA positive-strand viruses RNA-
directed RNA polymerase family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; X02144; CAA26085.1; -; Genomic_RNA.
EMBL; X02144; CAA26082.1; -; Genomic_RNA.
PIR; A04195; WMTM8T.
RefSeq; NP_078446.1; NC_002692.1.
RefSeq; NP_078447.1; NC_002692.1.
PDB; 3VKW; X-ray; 1.90 A; A=666-1111.
PDB; 3WRX; X-ray; 2.50 A; C/D=666-1116.
PDB; 3WRY; X-ray; 2.30 A; C/D=666-1116.
PDBsum; 3VKW; -.
PDBsum; 3WRX; -.
PDBsum; 3WRY; -.
SMR; P03587; -.
GeneID; 920838; -.
GeneID; 920841; -.
KEGG; vg:920838; -.
KEGG; vg:920841; -.
OrthoDB; VOG09000048; -.
Proteomes; UP000001451; Genome.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO; GO:0008174; F:mRNA methyltransferase activity; IEA:InterPro.
GO; GO:0003723; F:RNA binding; IEA:InterPro.
GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
GO; GO:0006396; P:RNA processing; IEA:InterPro.
GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
InterPro; IPR002588; Alphavirus-like_MT_dom.
InterPro; IPR027417; P-loop_NTPase.
InterPro; IPR007094; RNA-dir_pol_PSvirus.
InterPro; IPR001788; Tymovirus_RNA-dep_RNA_pol.
Pfam; PF00978; RdRP_2; 1.
Pfam; PF01443; Viral_helicase1; 1.
Pfam; PF01660; Vmethyltransf; 1.
SUPFAM; SSF52540; SSF52540; 1.
PROSITE; PS51743; ALPHAVIRUS_MT; 1.
PROSITE; PS51657; PSRV_HELICASE; 1.
PROSITE; PS50507; RDRP_SSRNA_POS; 1.
1: Evidence at protein level;
3D-structure; ATP-binding; Complete proteome; Helicase; Hydrolase;
Nucleotide-binding; Nucleotidyltransferase;
RNA suppression of termination; RNA-directed RNA polymerase;
Suppressor of RNA silencing; Transferase; Viral RNA replication.
CHAIN 1 1616 Replicase large subunit.
/FTId=PRO_0000041194.
CHAIN 1 1116 Replicase small subunit.
/FTId=PRO_0000041195.
DOMAIN 72 281 Alphavirus-like MT. {ECO:0000255|PROSITE-
ProRule:PRU01079}.
DOMAIN 801 963 (+)RNA virus helicase ATP-binding.
DOMAIN 964 1116 (+)RNA virus helicase C-terminal.
DOMAIN 1380 1493 RdRp catalytic. {ECO:0000255|PROSITE-
ProRule:PRU00539}.
NP_BIND 833 840 ATP. {ECO:0000255}.
REGION 50 458 Methyltransferase.
REGION 830 1085 Helicase.
MUTAGEN 349 349 C->A: Loss of RNA silencing suppression
activity. {ECO:0000269|PubMed:14512550}.
HELIX 672 675 {ECO:0000244|PDB:3WRY}.
HELIX 676 679 {ECO:0000244|PDB:3VKW}.
HELIX 684 687 {ECO:0000244|PDB:3VKW}.
HELIX 701 729 {ECO:0000244|PDB:3VKW}.
STRAND 730 732 {ECO:0000244|PDB:3VKW}.
STRAND 740 746 {ECO:0000244|PDB:3VKW}.
TURN 747 750 {ECO:0000244|PDB:3VKW}.
STRAND 751 754 {ECO:0000244|PDB:3VKW}.
STRAND 756 758 {ECO:0000244|PDB:3VKW}.
STRAND 762 768 {ECO:0000244|PDB:3VKW}.
STRAND 773 777 {ECO:0000244|PDB:3VKW}.
STRAND 782 784 {ECO:0000244|PDB:3VKW}.
STRAND 791 797 {ECO:0000244|PDB:3VKW}.
HELIX 798 800 {ECO:0000244|PDB:3VKW}.
HELIX 804 813 {ECO:0000244|PDB:3VKW}.
STRAND 817 819 {ECO:0000244|PDB:3WRY}.
STRAND 826 833 {ECO:0000244|PDB:3VKW}.
HELIX 839 846 {ECO:0000244|PDB:3VKW}.
TURN 849 851 {ECO:0000244|PDB:3VKW}.
STRAND 853 857 {ECO:0000244|PDB:3VKW}.
HELIX 859 869 {ECO:0000244|PDB:3VKW}.
TURN 870 872 {ECO:0000244|PDB:3VKW}.
TURN 879 881 {ECO:0000244|PDB:3VKW}.
STRAND 882 884 {ECO:0000244|PDB:3VKW}.
HELIX 885 890 {ECO:0000244|PDB:3VKW}.
TURN 891 893 {ECO:0000244|PDB:3VKW}.
STRAND 894 896 {ECO:0000244|PDB:3WRY}.
STRAND 901 905 {ECO:0000244|PDB:3VKW}.
HELIX 908 910 {ECO:0000244|PDB:3VKW}.
HELIX 913 922 {ECO:0000244|PDB:3VKW}.
STRAND 926 932 {ECO:0000244|PDB:3VKW}.
HELIX 950 953 {ECO:0000244|PDB:3VKW}.
STRAND 958 963 {ECO:0000244|PDB:3VKW}.
STRAND 965 968 {ECO:0000244|PDB:3VKW}.
HELIX 971 978 {ECO:0000244|PDB:3VKW}.
STRAND 981 983 {ECO:0000244|PDB:3VKW}.
STRAND 995 999 {ECO:0000244|PDB:3VKW}.
HELIX 1003 1005 {ECO:0000244|PDB:3VKW}.
TURN 1008 1010 {ECO:0000244|PDB:3VKW}.
STRAND 1015 1021 {ECO:0000244|PDB:3VKW}.
HELIX 1022 1029 {ECO:0000244|PDB:3VKW}.
TURN 1030 1032 {ECO:0000244|PDB:3VKW}.
STRAND 1034 1038 {ECO:0000244|PDB:3WRY}.
HELIX 1040 1042 {ECO:0000244|PDB:3VKW}.
STRAND 1047 1054 {ECO:0000244|PDB:3VKW}.
HELIX 1068 1074 {ECO:0000244|PDB:3VKW}.
STRAND 1075 1087 {ECO:0000244|PDB:3VKW}.
HELIX 1090 1100 {ECO:0000244|PDB:3VKW}.
HELIX 1103 1107 {ECO:0000244|PDB:3VKW}.
SEQUENCE 1616 AA; 183567 MW; A8EC8929B5CF7CAF CRC64;
MAYTQTATSS ALLETVRGNN TLVNDLAKRR LYDTAVDEFN ARDRRPKVNF SKVVSEEQTL
IATKAYPEFQ ITFYNTQNAV HSLAGGLRSL ELEYLMMQIP YGSLTYDIGG NFASHLFKGR
AYVHCCMPNL DVRDIMRHEG QKDSIELYLS RLERGNKHVP NFQKEAFDRY AEMPNEVVCH
DTFQTCRHSQ ECYTGRVYAI ALHSIYDIPA DEFGAALLRK NVHVCYAAFH FSENLLLEDS
HVNLDEINAC FQRDGDRLTF SFASESTLNY SHSYSNILKY VCKTYFPASN REVYMKEFLV
TRVNTWFCKF SRIDTFLLYK GVAHKGVDSE QFYKAMEDAW HYKKTLAMCN SERILLEDSS
SVNYWFPKMR DMVIVPLFDI SLETSKRTRK EVLVSKDFVY TVLNHIRTYQ AKALTYSNVL
SFVESIRSRV IINGVTARSE WDVDKSLLQS LSMTFFLHTK LAVLKDDLLI SKFALGPKTV
SQHVWDEISL AFGNAFPSIK ERLINRKLIK ITENALEIRV PDLYVTFHDR LVSEYKMSVD
MPVLDIRKKM EETEEMYNAL SELSVLKNSD KFDVDVFSQM CQSLEVDPMT AAKVIVAVMS
NESGLTLTFE QPTEANVALA LQDSEKASDG ALVVTSRDVE EPSIKGSMAR GELQLAGLSG
DVPESSYTRS EEIESLEQFH MATASSLIHK QMCSIVYTGP LKVQQMKNFI DSLVASLSAA
VSNLVKILKD TAAIDLETRQ KFGVLDVASK RWLVKPSAKN HAWGVVETHA RKYHVALLEH
DEFGIITCDN WRRVAVSSES VVYSDMAKLR TLRRLLKDGE PHVSSAKVVL VDGVPGCGKT
KEILSRVNFE EDLILVPGRQ AAEMIRRRAN ASGIIVATKD NVRTVDSFLM NYGKGARCQF
KRLFIDEGLM LHTGCVNFLV EMSLCDIAYV YGDTQQIPYI NRVTGFPYPA HFAKLEVDEV
ETRRTTLRCP ADVTHFLNQR YEGHVMCTSS EKKSVSQEMV SGAASINPVS KPLKGKILTF
TQSDKEALLS RGYADVHTVH EVQGETYADV SLVRLTPTPV SIIARDSPHV LVSLSRHTKS
LKYYTVVMDP LVSIIRDLER VSSYLLDMYK VDAGTQXQLQ VDSVFKNFNL FVAAPKTGDI
SDMQFYYDKC LPGNSTLLNN YDAVTMKLTD ISLNVKDCIL DMSKSVAAPK DVKPTLIPMV
RTAAEMPRQT GLLENLVAMI KRNFNSPELS GVVDIENTAS LVVDKFFDSY LLKEKRKPNK
NFSLFSRESL NRWIAKQEQV TIGQLADFDF VDLPAVDQYR HMIKAQPKQK LDLSIQTEYP
ALQTIVYHSK KINAIFGPLF SELTRQLLDS IDSSRFLFFT RKTPAQIEDF FGDLDSHVPM
DVLELDVSKY DKSQNEFHCA VEYEIWRRLG LEDFLAEVWK QGHRKTTLKD YTAGIKTCLW
YQRKSGDVTT FIGNTVIIAS CLASMLPMEK LIKGAFCGDD SLLYFPKGCE YPDIQQAANL
MWNFEAKLFK KQYGYFCGRY VIHHDRGCIV YYDPLKLISK LGAKHIKDWD HLEEFRRSLC
DVAESLNNCA YYTQLDDAVG EVHKTAPPGS FVYKSLVKYL SDKVLFRSLF LDGSSC


Related products :

Catalog number Product name Quantity
10-663-45516 Measles Virus Large structural Protein RNA Polymerase - Protein L; Transcriptase; Replicase N_A 0.5 mg
10-663-45516 Measles Virus Large structural Protein RNA Polymerase - Protein L; Transcriptase; Replicase N_A 0.1 mg
10-663-45516 Measles Virus Large structural Protein RNA Polymerase - Protein L; Transcriptase; Replicase N_A 1 mg
10-663-45518 Measles Virus Large Polymerase (MEVLP-29) - Protein L; Transcriptase; Replicase N_A 0.5 mg
10-663-45518 Measles Virus Large Polymerase (MEVLP-29) - Protein L; Transcriptase; Replicase N_A 1 mg
10-663-45518 Measles Virus Large Polymerase (MEVLP-29) - Protein L; Transcriptase; Replicase N_A 0.1 mg
EIAAB35820 BN51,BN51T,DNA-directed RNA polymerase III subunit D,DNA-directed RNA polymerase III subunit RPC4,Homo sapiens,Human,POLR3D,Protein BN51,RNA polymerase III 47 kDa subunit,RNA polymerase III subunit C4
EIAAB35784 DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,Homo sapiens,Human,POLR2,POLR2A,RNA polymerase II subunit B1,RNA-di
EIAAB35736 A190,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Homo sapiens,Human,POLR1A,RNA polymerase I 194 kDa subunit,RNA pol
EIAAB35785 DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,Mouse,Mus musculus,Polr2a,RNA polymerase II subunit B1,Rpii215,Rpo2
EIAAB35833 DNA-directed RNA polymerase III subunit H,DNA-directed RNA polymerase III subunit RPC8,Homo sapiens,Human,KIAA1665,POLR3H,RNA polymerase III subunit 22.9 kDa subunit,RNA polymerase III subunit C8,RPC2
EIAAB35737 DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Mouse,Mus musculus,Polr1a,RNA polymerase I 194 kDa subunit,RNA polymera
EIAAB35808 DNA-directed RNA polymerase III largest subunit,DNA-directed RNA polymerase III subunit A,DNA-directed RNA polymerase III subunit RPC1,Homo sapiens,Human,POLR3A,RNA polymerase III 155 kDa subunit,RNA
EIAAB35735 A194,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,DNA-directed RNA polymerase I subunit RPA1,Polr1a,Rat,Rattus norvegicus,RNA polymerase I 194 kDa subunit,RNA
EIAAB35809 DNA-directed RNA polymerase III subunit K,DNA-directed RNA polymerase III subunit RPC10,Homo sapiens,hRPC11,HsC11p,Human,My010,POLR3K,RNA polymerase III 12.5 kDa subunit,RNA polymerase III subunit C10
EIAAB35812 C128,DNA-directed RNA polymerase III 127.6 kDa polypeptide,DNA-directed RNA polymerase III subunit B,DNA-directed RNA polymerase III subunit RPC2,Homo sapiens,Human,POLR3B,RNA polymerase III subunit C
EIAAB35792 DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,DNA-directed RNA polymerase II subunit RPB2,Homo sapiens,Human,POLR2B,RNA polymerase II subunit 2,RNA polyme
EIAAB35794 A-152E5.7,DNA-directed RNA polymerase II 33 kDa polypeptide,DNA-directed RNA polymerase II subunit C,DNA-directed RNA polymerase II subunit RPB3,Homo sapiens,Human,POLR2C,RNA polymerase II subunit 3,R
EIAAB35787 DNA-directed RNA polymerase II subunit J-1,DNA-directed RNA polymerase II subunit RPB11-a,Homo sapiens,Human,POLR2J,POLR2J1,RNA polymerase II 13.3 kDa subunit,RNA polymerase II subunit B11-a,RPB11a
EIAAB35832 Bos taurus,Bovine,DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide,DNA-directed RNA polymerase III subunit H,DNA-directed RNA polymerase III subunit RPC8,POLR3H,RNA polymerase III subunit
EIAAB35793 DNA-directed RNA polymerase II 33 kDa polypeptide,DNA-directed RNA polymerase II subunit C,DNA-directed RNA polymerase II subunit RPB3,Mouse,Mus musculus,Polr2c,RNA polymerase II subunit 3,RNA polymer
EIAAB35791 DNA-directed RNA polymerase II 140 kDa polypeptide,DNA-directed RNA polymerase II subunit B,DNA-directed RNA polymerase II subunit RPB2,Mouse,Mus musculus,Polr2b,RNA polymerase II subunit 2,RNA polyme
EIAAB35813 C128,DNA-directed RNA polymerase III 127.6 kDa polypeptide,DNA-directed RNA polymerase III subunit B,DNA-directed RNA polymerase III subunit RPC2,Mouse,Mus musculus,Polr3b,RNA polymerase III subunit C
EIAAB35827 DNA-directed RNA polymerase III subunit G,DNA-directed RNA polymerase III subunit RPC7,Homo sapiens,Human,POLR3G,RNA polymerase III 32 kDa subunit,RNA polymerase III subunit C7,RPC32
EIAAB35815 DNA-directed RNA polymerase III subunit C,DNA-directed RNA polymerase III subunit RPC3,Homo sapiens,Human,POLR3C,RNA polymerase III 62 kDa subunit,RNA polymerase III subunit C3,RPC62


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur