Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Reverse rubrerythrin-2 (revRbr 2) (NADH peroxidase) (NPXase) (Npx) (EC 1.11.1.1) (Rubperoxin 2) (Rpr 2)

 RRBR2_CLOAB             Reviewed;         181 AA.
Q97D83;
08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
01-OCT-2001, sequence version 1.
28-FEB-2018, entry version 99.
RecName: Full=Reverse rubrerythrin-2;
Short=revRbr 2;
AltName: Full=NADH peroxidase;
Short=NPXase;
Short=Npx;
EC=1.11.1.1;
AltName: Full=Rubperoxin 2;
Short=Rpr 2;
Name=rbr3B; Synonyms=hsp21, rpr2; OrderedLocusNames=CA_C3597;
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG
5710 / VKM B-1787).
Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
Clostridium.
NCBI_TaxID=272562;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q.,
Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I.,
Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P.,
Daly M.J., Bennett G.N., Koonin E.V., Smith D.R.;
"Genome sequence and comparative analysis of the solvent-producing
bacterium Clostridium acetobutylicum.";
J. Bacteriol. 183:4823-4838(2001).
[2]
PROTEIN SEQUENCE OF 1-20, GENE NAME, AND INDUCTION BY HEAT; AIR AND
H(2)O(2).
STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
PubMed=15336429; DOI=10.1111/j.1574-6968.2004.tb09763.x;
May A., Hillmann F., Riebe O., Fischer R.J., Bahl H.;
"A rubrerythrin-like oxidative stress protein of Clostridium
acetobutylicum is encoded by a duplicated gene and identical to the
heat shock protein Hsp21.";
FEMS Microbiol. Lett. 238:249-254(2004).
[3]
IDENTIFICATION BY MASS SPECTROMETRY, AND INDUCTION BY O(2).
STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
PubMed=15280011; DOI=10.1016/j.febslet.2004.06.047;
Kawasaki S., Ishikura J., Watamura Y., Niimura Y.;
"Identification of O2-induced peptides in an obligatory anaerobe,
Clostridium acetobutylicum.";
FEBS Lett. 571:21-25(2004).
[4]
INDUCTION BY VARIOUS ENVIRONMENTAL STRESS CONDITIONS.
STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
PubMed=16463182; DOI=10.1007/s00203-006-0091-y;
Hillmann F., Fischer R.J., Bahl H.;
"The rubrerythrin-like protein Hsp21 of Clostridium acetobutylicum is
a general stress protein.";
Arch. Microbiol. 185:270-276(2006).
[5]
REPRESSION BY PERR.
STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
PubMed=18430081; DOI=10.1111/j.1365-2958.2008.06192.x;
Hillmann F., Fischer R.J., Saint-Prix F., Girbal L., Bahl H.;
"PerR acts as a switch for oxygen tolerance in the strict anaerobe
Clostridium acetobutylicum.";
Mol. Microbiol. 68:848-860(2008).
[6]
INDUCTION BY O(2), AND REPRESSION BY PERR.
STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
PubMed=19648241; DOI=10.1128/JB.00351-09;
Hillmann F., Doring C., Riebe O., Ehrenreich A., Fischer R.J.,
Bahl H.;
"The role of PerR in O2-affected gene expression of Clostridium
acetobutylicum.";
J. Bacteriol. 191:6082-6093(2009).
[7]
FUNCTION, CATALYTIC ACTIVITY, COFACTOR, ENZYME REGULATION, ROLE IN
OXIDATIVE STRESS RESISTANCE, AND SUBUNIT.
STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
PubMed=19118342; DOI=10.1099/mic.0.022756-0;
Riebe O., Fischer R.J., Wampler D.A., Kurtz D.M. Jr., Bahl H.;
"Pathway for H2O2 and O2 detoxification in Clostridium
acetobutylicum.";
Microbiology 155:16-24(2009).
-!- FUNCTION: Functions as the terminal component of an NADH
peroxidase (NADH:H(2)O(2) oxidoreductase) when using
NADH:rubredoxin oxidoreductase (NROR) as the electron transport
intermediary from NADH to revRbr 2. Plays an important role in the
oxidative stress defense system in C.acetobutylicum, an obligate
anaerobic bacterium. Also exhibits NADH oxidase (NADH:O(2)
oxidoreductase) activity in vitro, which is 100-fold lesser than
that of FprA1/2 using the same electron transfer components.
Therefore, its predominant function is most likely as a scavenger
of its preferred substrate, H(2)O(2).
{ECO:0000269|PubMed:19118342}.
-!- CATALYTIC ACTIVITY: NADH + H(2)O(2) = NAD(+) + 2 H(2)O.
{ECO:0000269|PubMed:19118342}.
-!- COFACTOR:
Name=Fe(3+); Xref=ChEBI:CHEBI:29034;
Evidence={ECO:0000269|PubMed:19118342};
Note=Binds 3 Fe(3+) ions per subunit.
{ECO:0000269|PubMed:19118342};
-!- ENZYME REGULATION: Rubredoxin (Rd) increases the NADH consumption
rate by serving as an intermediary electron-transfer shuttle
between NROR and revRbr. {ECO:0000269|PubMed:19118342}.
-!- SUBUNIT: Homotetramer. {ECO:0000269|PubMed:19118342}.
-!- INDUCTION: Up-regulated by heat and oxidative stress (exposure to
air, O(2) and H(2)O(2)) (at mRNA and protein levels). Various
other environmental stress conditions such as an increase of the
pH of the growth medium from 4.5 to 6.2, addition of the salt NaCl
or of the solvent butanol, and lowering the incubation temperature
also result in transiently increased transcript levels. Is also
expressed under non-stressful conditions. Repressed by PerR.
{ECO:0000269|PubMed:15280011, ECO:0000269|PubMed:15336429,
ECO:0000269|PubMed:16463182, ECO:0000269|PubMed:18430081,
ECO:0000269|PubMed:19648241}.
-!- MISCELLANEOUS: This protein has been named "reverse" rubrerythrin
(revRbr) because the order of the two functional domains is
reversed compared to "classical" rubrerythrins: the rubredoxin-
like FeS4 domain is located at the N-terminus and the ferritin-
like diiron domain at the C-terminus.
-!- MISCELLANEOUS: A revRbr-overexpressing strain of C.acetobutylicum
shows greatly increased tolerance to H(2)O(2) and O(2) exposure.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AE001437; AAK81520.1; -; Genomic_DNA.
PIR; E97341; E97341.
RefSeq; NP_350180.1; NC_003030.1.
RefSeq; WP_010966860.1; NC_003030.1.
ProteinModelPortal; Q97D83; -.
SMR; Q97D83; -.
STRING; 272562.CA_C3597; -.
DNASU; 1119779; -.
EnsemblBacteria; AAK81520; AAK81520; CA_C3597.
GeneID; 1119779; -.
KEGG; cac:CA_C3597; -.
PATRIC; fig|272562.8.peg.3786; -.
eggNOG; ENOG4105KY8; Bacteria.
eggNOG; COG1592; LUCA.
HOGENOM; HOG000153104; -.
OMA; EKNWADE; -.
BRENDA; 1.11.1.1; 1452.
Proteomes; UP000000814; Chromosome.
GO; GO:0009055; F:electron transfer activity; IDA:UniProtKB.
GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
GO; GO:0016692; F:NADH peroxidase activity; IDA:UniProtKB.
GO; GO:0071469; P:cellular response to alkaline pH; IDA:UniProtKB.
GO; GO:0070417; P:cellular response to cold; IDA:UniProtKB.
GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
GO; GO:0071453; P:cellular response to oxygen levels; IDA:UniProtKB.
GO; GO:0071472; P:cellular response to salt stress; IDA:UniProtKB.
GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:UniProtKB.
Gene3D; 1.20.1260.10; -; 1.
InterPro; IPR012347; Ferritin-like.
InterPro; IPR009040; Ferritin-like_diiron.
InterPro; IPR009078; Ferritin-like_SF.
InterPro; IPR024934; Rubredoxin-like_dom.
InterPro; IPR003251; Rubrerythrin.
Pfam; PF02915; Rubrerythrin; 1.
SUPFAM; SSF47240; SSF47240; 1.
PROSITE; PS50905; FERRITIN_LIKE; 1.
PROSITE; PS50903; RUBREDOXIN_LIKE; 1.
1: Evidence at protein level;
Complete proteome; Detoxification; Direct protein sequencing;
Electron transport; Iron; Metal-binding; NAD; Oxidoreductase;
Peroxidase; Reference proteome; Stress response; Transport.
CHAIN 1 181 Reverse rubrerythrin-2.
/FTId=PRO_0000405535.
DOMAIN 1 35 Rubredoxin-like. {ECO:0000255|PROSITE-
ProRule:PRU00241}.
DOMAIN 52 181 Ferritin-like diiron.
{ECO:0000255|PROSITE-ProRule:PRU00085}.
METAL 6 6 Iron 1. {ECO:0000250}.
METAL 9 9 Iron 1. {ECO:0000250}.
METAL 22 22 Iron 1. {ECO:0000250}.
METAL 25 25 Iron 1. {ECO:0000250}.
METAL 69 69 Iron 2. {ECO:0000250}.
METAL 102 102 Iron 2. {ECO:0000250}.
METAL 102 102 Iron 3. {ECO:0000250}.
METAL 132 132 Iron 3. {ECO:0000250}.
METAL 165 165 Iron 2. {ECO:0000250}.
METAL 165 165 Iron 3. {ECO:0000250}.
METAL 168 168 Iron 3. {ECO:0000250}.
SEQUENCE 181 AA; 20107 MW; 181DCC858E7F8C93 CRC64;
MKKFKCVVCG YIYTGEDAPE KCPVCGAGKD KFVEVKDEGE GWADEHKIGI AKGVDKEVLE
GLRANFTGEC TEVGMYLAMA RQADREGYPE VAEAYKRIAF EEAEHASKFA ELLGEVVVAD
TKTNLQMRVD AEKGACEGKK ELATLAKKLN YDAIHDTVHE MCKDEARHGS AFRGLLNRYF
K


Related products :

Catalog number Product name Quantity
'AP21350AF-N NADH peroxidase IgG antibody Ab host: Rabbit 10 mg
'AP21350BT-N NADH peroxidase IgG antibody Ab host: Rabbit 1 ml
NE107/7S rabbit IgG against Streptococcus faecalis NADH peroxidase 10 mg
AP21350BT-N NADH peroxidase Rabbit IgG antibody Ab Biotin 1 ml
YNNE1077S NADH Peroxidase, Rabbit anti_S. faecalis 10 mg.
'AP21350BT-N NADH peroxidase antibody Isotype IgG Host Rabbit 1 ml
YNNE107Bio NADH Peroxidase, Rabbit anti_S. faecalis, Biotin 1 ml.
'AP21350AF-N NADH peroxidase antibody Isotype IgG Host Rabbit 10 mg
AP21350AF-N NADH peroxidase Rabbit IgG antibody Ab Azide Free 10 mg
NE107/Bio rabbit IgG against Streptococcus faecalis NADH peroxidase, conjugated with Biotin 1 ml
orb22422 Rat Peroxidase-Anti-Peroxidase Polyclonal Soluble rat peroxidase-anti-peroxidase immune complex. Peroxidase staining of unlabelled rat IgG antibodies. 0.25 ml
orb21114 NADH Peroxidase antibody Polyclonal Antibody Host: Rabbit 10mg
orb21115 NADH Peroxidase antibody Polyclonal Antibodies Primary antibodies 1 ml
orb21115 NADH Peroxidase antibody Polyclonal Antibody Host: Rabbit 1ml
orb21114 NADH Peroxidase antibody Polyclonal Antibodies Primary antibodies 10 mg
orb21309 Sheep Peroxidase-Anti-Peroxidase Polyclonal Soluble sheep peroxidase-anti-peroxidase immune complex. Peroxidase staining of unlabelled sheep IgG antibodies. 1 ml
orb22294 Rabbit Peroxidase-Anti-Peroxidase Polyclonal Soluble rabbit peroxidase-anti-peroxidase immune complex. Peroxidase staining of unlabelled Rabbit IgG antibodies. 1 ml
orb22146 Goat Peroxidase-Anti-Peroxidase Polyclonal Soluble goat peroxidase-anti-peroxidase immune complex. Peroxidase staining of unlabelled goat IgG antibodies. 1 ml
EIAAB26818 Bos taurus,Bovine,NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial,NADH dehydrogenase subunit II,NADH-ubiquinone oxidoreductase 24 kDa subunit,NDUFV2
EIAAB26811 CI-51kD,Complex I-51kD,Homo sapiens,Human,NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial,NADH dehydrogenase flavoprotein 1,NADH-ubiquinone oxidoreductase 51 kDa subunit,NDUFV1,UQOR1
EIAAB28147 Mouse,Mtnd5,mt-Nd5,Mus musculus,NADH dehydrogenase subunit 5,NADH-ubiquinone oxidoreductase chain 5,Nd5
201-20-3704 NDUFS3{NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)}rabbit.pAb 0.2ml
EIAAB28103 MTND1,MT-ND1,NADH dehydrogenase subunit 1,NADH1,NADH-ubiquinone oxidoreductase chain 1,ND1,Pig,Sus scrofa
201-20-3707 NDUFS7{NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)}rabbit.pAb 0.2ml
EIAAB28100 Mouse,Mtnd1,mt-Nd1,Mus musculus,NADH dehydrogenase subunit 1,NADH-ubiquinone oxidoreductase chain 1,Nd1


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur