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SEC24 homolog B, COPII coat complex component

 E1BPR4_BOVIN            Unreviewed;      1247 AA.
E1BPR4;
02-NOV-2010, integrated into UniProtKB/TrEMBL.
02-NOV-2010, sequence version 1.
12-SEP-2018, entry version 48.
SubName: Full=SEC24 homolog B, COPII coat complex component {ECO:0000313|Ensembl:ENSBTAP00000045766};
Name=SEC24B {ECO:0000313|Ensembl:ENSBTAP00000045766,
ECO:0000313|VGNC:VGNC:34414};
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000045766, ECO:0000313|Proteomes:UP000009136};
[1] {ECO:0000313|Ensembl:ENSBTAP00000045766, ECO:0000313|Proteomes:UP000009136}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000045766,
ECO:0000313|Proteomes:UP000009136};
PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42;
Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C.,
Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S.,
Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.;
"A whole-genome assembly of the domestic cow, Bos taurus.";
Genome Biol. 10:R42.01-R42.10(2009).
[2] {ECO:0000313|Ensembl:ENSBTAP00000045766}
IDENTIFICATION.
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000045766};
Ensembl;
Submitted (MAR-2016) to UniProtKB.
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EMBL; DAAA02016542; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02016543; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; DAAA02016544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9913.ENSBTAP00000045766; -.
PaxDb; E1BPR4; -.
PRIDE; E1BPR4; -.
Ensembl; ENSBTAT00000048781; ENSBTAP00000045766; ENSBTAG00000010945.
VGNC; VGNC:34414; SEC24B.
eggNOG; KOG1985; Eukaryota.
eggNOG; COG5028; LUCA.
GeneTree; ENSGT00590000082962; -.
InParanoid; E1BPR4; -.
OMA; NILPMTP; -.
OrthoDB; EOG091G011M; -.
TreeFam; TF354244; -.
Reactome; R-BTA-204005; COPII-mediated vesicle transport.
Reactome; R-BTA-2132295; MHC class II antigen presentation.
Reactome; R-BTA-5694530; Cargo concentration in the ER.
Reactome; R-BTA-983170; Antigen Presentation: Folding, assembly and peptide loading of class I MHC.
Proteomes; UP000009136; Chromosome 6.
Bgee; ENSBTAG00000010945; Expressed in 10 organ(s), highest expression level in testis.
GO; GO:0030127; C:COPII vesicle coat; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0000139; C:Golgi membrane; IEA:GOC.
GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
GO; GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Ensembl.
GO; GO:0090110; P:cargo loading into COPII-coated vesicle; IEA:Ensembl.
GO; GO:0021747; P:cochlear nucleus development; IEA:Ensembl.
GO; GO:0060982; P:coronary artery morphogenesis; IEA:Ensembl.
GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
GO; GO:0061156; P:pulmonary artery morphogenesis; IEA:Ensembl.
GO; GO:1901301; P:regulation of cargo loading into COPII-coated vesicle; IEA:Ensembl.
GO; GO:0090178; P:regulation of establishment of planar polarity involved in neural tube closure; IEA:Ensembl.
Gene3D; 3.40.20.10; -; 1.
Gene3D; 3.40.50.410; -; 1.
InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
InterPro; IPR007123; Gelsolin-like_dom.
InterPro; IPR036180; Gelsolin-like_dom_sf.
InterPro; IPR006900; Sec23/24_helical_dom.
InterPro; IPR036175; Sec23/24_helical_dom_sf.
InterPro; IPR006896; Sec23/24_trunk_dom.
InterPro; IPR012990; Sec23_24_beta_S.
InterPro; IPR036465; vWFA_dom_sf.
InterPro; IPR006895; Znf_Sec23_Sec24.
InterPro; IPR036174; Znf_Sec23_Sec24_sf.
Pfam; PF00626; Gelsolin; 1.
Pfam; PF08033; Sec23_BS; 1.
Pfam; PF04815; Sec23_helical; 1.
Pfam; PF04811; Sec23_trunk; 1.
Pfam; PF04810; zf-Sec23_Sec24; 1.
SUPFAM; SSF53300; SSF53300; 1.
SUPFAM; SSF81811; SSF81811; 1.
SUPFAM; SSF82754; SSF82754; 1.
SUPFAM; SSF82919; SSF82919; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000009136};
Protein transport {ECO:0000256|SAAS:SAAS00748918};
Reference proteome {ECO:0000313|Proteomes:UP000009136};
Transport {ECO:0000256|SAAS:SAAS00748918}.
DOMAIN 580 616 zf-Sec23_Sec24.
{ECO:0000259|Pfam:PF04810}.
DOMAIN 653 892 Sec23_trunk. {ECO:0000259|Pfam:PF04811}.
DOMAIN 897 981 Sec23_BS. {ECO:0000259|Pfam:PF08033}.
DOMAIN 992 1092 Sec23_helical.
{ECO:0000259|Pfam:PF04815}.
DOMAIN 1119 1192 Gelsolin-like.
{ECO:0000259|Pfam:PF00626}.
SEQUENCE 1247 AA; 135399 MW; A8EE61E4A49A4C7E CRC64;
MSAPAGSPHP AASARIPPKL GGAAASGAAA PAGPGPGPHQ QNGPAQNQMQ VPSEYGLPPQ
NYIVPSGHYS QGPGKMTSLP LQSQSGDYYS GLYTVPTQNV ATPNTASQQA GAQQMYGRAP
PAPHAVGSTP GSFQGASSSA SHLHTSASQP YSSFVNHYNS PATYSASSSV ASQGFPSTCG
HYALSTVSNA AYPSISYPSL PAGDPYGQQM FTSQNAPAVR PIRDNSFSGQ NTAVSHPSPL
PPPPSRQYHQ QQSLSGYSTF SWSAPGLPST QDNLIRNHTS LATASNPTNT VMQNVQPPKS
SPVVSTVVSG ASSTRMPPAA NRPVEPVASV TQPSELLQQK GMQYGEYVNN QASSAPTPLS
STSDDEEEEE EDEEAGVDSS STTSSASPMP NSYDALEGGS YPDVLSSSAS SPAPDPAPDP
APAPAPAAPQ PSKMPKPFGY GYPTLQPGYQ NATAPLNSGG PPSSPVYSGF QQYAQYPGMN
QLSSSLGGLN LQSSSQPESL RPVNLTQERN ILPMTPVWAP VPNLNLDLKK LNCSPDSFRC
TLTNIPQTQA LLNKAKLPLG LLLHPFRDLT QLPVITSNTI VRCRSCRTYI NPFVSFIDQR
RWKCNLCYRV NDVPEEFMYN PLTRSYGEPH KRPEVQNSTV EFIASSDYML RPPQPAVYLF
VLDVSHNAVE AGYLTILCQS LLENLDKLPG DSRTRIGFVT FDSTIHFYNL QEGLSQPQML
IVSDIDDVFL PTPDSLLVNL YESKELIKDL LNALPNMFTN TRETHSALGP ALQAAFKLMS
PTGGRVSLFQ TQLPSLGAGL LQSREDPNQR SSTKVVQHLG PATDFYKKLA LDCSGQQTAV
DLFLLSSQYS DLASLACMSK YSAGCIYYYP SFHYTHNPSQ AEKLQKDLKR YLTRKIGFEA
VMRIRCTKGL SMHTFHGNFF VRSTDLLSLA NINPDAGFAV QLSIEESLTD TSLVCFQTAL
LYTSSKGERR IRVHTLCLPV VSSLADVYAG VDVQAAICLL ANMAVDRSIS SSLSDARDAL
VNAVVDSLSA YGSTVSNVQH SGLIAPSSLK LFPLYVLALL KQKAFRTGTS TRLDDRVYAM
CQIKCQPLVH LMKMIHPNLY RIDRLTDEGA IHVNDRVVPQ PPLQKLSAEK LTREGPAFML
DDFEVFYIWI GKSCDNNFIE DVLGYPDFAS IPQKMTHLPE LDTLSSERAR SFITWLRDSR
PLSPVLHVVK DESPAKTEFF QHLIEDRTEA AFSYYEFLLH VQQQICK


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