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SEC24 homolog B, COPII coat complex component

 F6YGU5_HORSE            Unreviewed;      1176 AA.
F6YGU5;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
27-JUL-2011, sequence version 1.
12-SEP-2018, entry version 41.
SubName: Full=SEC24 homolog B, COPII coat complex component {ECO:0000313|Ensembl:ENSECAP00000014374};
Name=SEC24B {ECO:0000313|VGNC:VGNC:22793};
Equus caballus (Horse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000014374, ECO:0000313|Proteomes:UP000002281};
[1] {ECO:0000313|Ensembl:ENSECAP00000014374, ECO:0000313|Proteomes:UP000002281}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000014374,
ECO:0000313|Proteomes:UP000002281};
PubMed=19892987; DOI=10.1126/science.1178158;
Broad Institute Genome Sequencing Platform;
Broad Institute Whole Genome Assembly Team;
Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H.,
Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N.,
Penedo M.C.T., Raison J.M., Sharpe T., Vogel J., Andersson L.,
Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J.,
Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J.,
Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R.,
Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F.,
Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L.,
Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M.,
White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
"Genome sequence, comparative analysis, and population genetics of the
domestic horse.";
Science 326:865-867(2009).
[2] {ECO:0000313|Ensembl:ENSECAP00000014374}
IDENTIFICATION.
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000014374};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
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STRING; 9796.ENSECAP00000014374; -.
PaxDb; F6YGU5; -.
Ensembl; ENSECAT00000017682; ENSECAP00000014374; ENSECAG00000016518.
VGNC; VGNC:22793; SEC24B.
eggNOG; KOG1985; Eukaryota.
eggNOG; COG5028; LUCA.
GeneTree; ENSGT00590000082962; -.
InParanoid; F6YGU5; -.
OMA; NILPMTP; -.
OrthoDB; EOG091G011M; -.
TreeFam; TF354244; -.
Proteomes; UP000002281; Chromosome 2.
Bgee; ENSECAG00000016518; Expressed in 3 organ(s), highest expression level in adult mammalian kidney.
GO; GO:0030127; C:COPII vesicle coat; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0000139; C:Golgi membrane; IEA:GOC.
GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
GO; GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Ensembl.
GO; GO:0090110; P:cargo loading into COPII-coated vesicle; IEA:Ensembl.
GO; GO:0021747; P:cochlear nucleus development; IEA:Ensembl.
GO; GO:0060982; P:coronary artery morphogenesis; IEA:Ensembl.
GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
GO; GO:0061156; P:pulmonary artery morphogenesis; IEA:Ensembl.
GO; GO:1901301; P:regulation of cargo loading into COPII-coated vesicle; IEA:Ensembl.
GO; GO:0090178; P:regulation of establishment of planar polarity involved in neural tube closure; IEA:Ensembl.
Gene3D; 3.40.20.10; -; 1.
Gene3D; 3.40.50.410; -; 1.
InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
InterPro; IPR007123; Gelsolin-like_dom.
InterPro; IPR036180; Gelsolin-like_dom_sf.
InterPro; IPR006900; Sec23/24_helical_dom.
InterPro; IPR036175; Sec23/24_helical_dom_sf.
InterPro; IPR006896; Sec23/24_trunk_dom.
InterPro; IPR012990; Sec23_24_beta_S.
InterPro; IPR036465; vWFA_dom_sf.
InterPro; IPR006895; Znf_Sec23_Sec24.
InterPro; IPR036174; Znf_Sec23_Sec24_sf.
Pfam; PF00626; Gelsolin; 1.
Pfam; PF08033; Sec23_BS; 1.
Pfam; PF04815; Sec23_helical; 1.
Pfam; PF04811; Sec23_trunk; 1.
Pfam; PF04810; zf-Sec23_Sec24; 1.
SUPFAM; SSF53300; SSF53300; 1.
SUPFAM; SSF81811; SSF81811; 1.
SUPFAM; SSF82754; SSF82754; 1.
SUPFAM; SSF82919; SSF82919; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000002281};
Protein transport {ECO:0000256|SAAS:SAAS00748918};
Reference proteome {ECO:0000313|Proteomes:UP000002281};
Transport {ECO:0000256|SAAS:SAAS00748918}.
DOMAIN 510 546 zf-Sec23_Sec24.
{ECO:0000259|Pfam:PF04810}.
DOMAIN 583 822 Sec23_trunk. {ECO:0000259|Pfam:PF04811}.
DOMAIN 827 911 Sec23_BS. {ECO:0000259|Pfam:PF08033}.
DOMAIN 922 1022 Sec23_helical.
{ECO:0000259|Pfam:PF04815}.
DOMAIN 1049 1121 Gelsolin-like.
{ECO:0000259|Pfam:PF00626}.
SEQUENCE 1176 AA; 127518 MW; 5D6AA3D54C893050 CRC64;
GPAQNQMQFP SGYGLHPQNY IAPSGHYAQG PGKMTSLPLD SQHGDYYSGL YTVPTQNVVT
PNTAGQQPGA QQMYGRVLPA PHMAGSALGS FPGATSSASH VHTSASVNHH NSPAVGAANS
SVASQGFPST CGHYAMSTVS NAAYPRVSYS SPPAGDPYGQ QMFTSQNAPP VRPIRDNSFS
GQNTAISHPS PLPPPPPQQY HQEQSLSGYS TLSWSASGLP STQDNLLRNH TGSLATANNN
PTSPVADSLS SSVMQNVQPP VSSPVVSTVL SGASSARTPA AACHPAEPAA SVTQPSELFQ
QKGVDSSSTT SSASPGPNSY DALEGGSYPD MLSSSASSPA PDPAPESDPT SAPAPAAAQP
SKVAKPFGYG YPALQPGYQN AAAPPGAGPP SASPVYSGFQ QYAQQYPGLN QLSSGLGGLS
LQSAPQPESL RPVNLTQDRN VLPVTPVWAP VPNLNLDLRK LNCSPDSFRC TLTSIPQTQA
LLNKAKLPLG LLLHPFRDLT QLPVITSNTI VRCRSCRTYI NPFVSFIDQR RWKCNLCYRV
NDVPEEFMYN PLTRSYGEPH KRPEVQNSTV EFIASSDYML RPPQPAVYLF VLDVSHNAVE
AGYLTILCQS LLENLDKLPG DSRTRIGFLT FDSTIHFYDL QEGLSQPQML IVSEIDDVFL
PTPDSLLVNL HESKELIKDL LNALPTMFTN TRETHSALGP ALQAAFKLMS PTGGRVSVFQ
TQLPSLGAGL LQSREDPNQR SSTKVVQHLG PATDFYKKLA LDCSGQQTAV DLFLLSSQYS
DLASLACMSK YSAGCIYYYP SFHCTHNPSQ AEKLQKDLRR YLTRKIGFEA VMRIRCTKGL
SMHTFHGNFF VRSTDLLSLA NINPDAGFAV QLSIEESLTD TSLVCFQTAL LYTSSKGERR
IRVHTLCLPV VSSLADVYAG VDVQAAICLL ANMAVDRSVS SSLSDARDAL VNAVVDSLSA
YGSTISNLQH SALIAPSSLK LFPLYVLALL KQKAFRTGTS TRLDDRVYAM CQIKCQPLVH
LMKMIHPNLY RIDRLTDEGA IHVNDRVVPQ PPLQKLSAEK LTREGAFLMD CGSVFYIWIG
KSCDNNFIED VLGCPNFASI PQKMTHLPEL DTLSSERARS FITWLRDNRP LSPVLHVVKD
ESPAKTEFFQ HLIEDRTEAA FSYYEFLLHI QQHICK


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