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SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1

 F1NW71_CHICK            Unreviewed;       510 AA.
F1NW71;
03-MAY-2011, integrated into UniProtKB/TrEMBL.
30-NOV-2016, sequence version 3.
30-AUG-2017, entry version 45.
SubName: Full=SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 {ECO:0000313|Ensembl:ENSGALP00000010101};
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000010101, ECO:0000313|Proteomes:UP000000539};
[1] {ECO:0000313|Ensembl:ENSGALP00000010101, ECO:0000313|Proteomes:UP000000539}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000010101,
ECO:0000313|Proteomes:UP000000539};
PubMed=15592404; DOI=10.1038/nature03154;
International Chicken Genome Sequencing Consortium;
Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C.,
Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E.,
Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W.,
Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A., Kremitzki C.,
Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E.,
Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J.,
Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M.,
Paton B., Smith J., Morrice D., Daniels L., Tempest H.G.,
Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V.,
Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J.,
van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J.,
Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H.,
Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S.,
Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J.,
Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H.,
Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C.,
Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C.,
Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P.,
King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S.,
Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S.,
Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S.,
Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z.,
Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J.,
Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z.,
Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J.,
Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G.,
Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D.,
Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G.,
Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A.,
Mardis E.R., Wilson R.K.;
"Sequence and comparative analysis of the chicken genome provide
unique perspectives on vertebrate evolution.";
Nature 432:695-716(2004).
[2] {ECO:0000313|Ensembl:ENSGALP00000010101}
IDENTIFICATION.
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000010101};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00500}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSGALP00000010101}.
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EMBL; AADN04000472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AADN04000548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AADN04000549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AADN04006213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AADN04010080; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AADN04015351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9031.ENSGALP00000010101; -.
PaxDb; F1NW71; -.
Ensembl; ENSGALT00000010115; ENSGALP00000010101; ENSGALG00000006258.
eggNOG; KOG3555; Eukaryota.
eggNOG; ENOG410Y6A8; LUCA.
GeneTree; ENSGT00510000046429; -.
InParanoid; F1NW71; -.
OrthoDB; EOG091G086I; -.
TreeFam; TF317779; -.
Proteomes; UP000000539; Chromosome 13.
Bgee; ENSGALG00000006258; -.
GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
GO; GO:0031594; C:neuromuscular junction; ISS:UniProtKB.
GO; GO:0033268; C:node of Ranvier; ISS:UniProtKB.
GO; GO:0005578; C:proteinaceous extracellular matrix; IEA:InterPro.
GO; GO:0016528; C:sarcoplasm; ISS:UniProtKB.
GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; ISS:UniProtKB.
GO; GO:0008191; F:metalloendopeptidase inhibitor activity; ISS:UniProtKB.
GO; GO:0021953; P:central nervous system neuron differentiation; ISS:UniProtKB.
GO; GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.
GO; GO:0010951; P:negative regulation of endopeptidase activity; ISS:UniProtKB.
GO; GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.
GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
GO; GO:0007165; P:signal transduction; IEA:InterPro.
Gene3D; 4.10.800.10; -; 1.
InterPro; IPR011992; EF-hand-dom_pair.
InterPro; IPR002350; Kazal_dom.
InterPro; IPR019577; SPARC/Testican_Ca-bd-dom.
InterPro; IPR000716; Thyroglobulin_1.
Pfam; PF07648; Kazal_2; 1.
Pfam; PF10591; SPARC_Ca_bdg; 1.
Pfam; PF00086; Thyroglobulin_1; 1.
SMART; SM00280; KAZAL; 1.
SMART; SM00211; TY; 1.
SUPFAM; SSF100895; SSF100895; 1.
SUPFAM; SSF47473; SSF47473; 1.
SUPFAM; SSF57610; SSF57610; 1.
PROSITE; PS51465; KAZAL_2; 1.
PROSITE; PS00484; THYROGLOBULIN_1_1; 1.
PROSITE; PS51162; THYROGLOBULIN_1_2; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000000539};
Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00500,
ECO:0000256|SAAS:SAAS00485231};
Reference proteome {ECO:0000313|Proteomes:UP000000539}.
DOMAIN 201 252 Kazal-like.
{ECO:0000259|PROSITE:PS51465}.
DOMAIN 381 447 Thyroglobulin type-1.
{ECO:0000259|PROSITE:PS51162}.
DISULFID 419 426 {ECO:0000256|PROSITE-ProRule:PRU00500}.
SEQUENCE 510 AA; 56343 MW; 2C726ECE62F8A882 CRC64;
MAPDLVCWHG PRARIRPHTP AAADGAWRGL LALPPAASPT AARAAAAARR RGEGGGGGEG
GGGGERSAVR QQRAEMSGVL VIAAWCFLQV ESRHPEIITG SSNHGNFLDN DKWLSTVSQY
DKDKYWNKFR DDDYVRNWNP NKPFDQALDP SKDPCLKVKC SPHKVCVTHD YETATCVSRK
QLVHSIRQKK GNLAQKHWAG PANMVKCKPC PTVHASPVCG SDGHTYTTKC KLEFHACTSG
KTITARCEGP CPCLPGPESP KHKTEKTACT DKELRSLASR LKDWFGALHE DANRVIKPTS
SETAQGRFDT SILPICKDSL GWMFNKLDMN YDLLLDPSEI SAIYLDKYEP CVKPLFNSCD
SFKDGKLSNN EWCYCFQKPG GLPCQNEMNR IQKLSRGKSL LGAFIPRCNE EGYYKATQCH
GSTGQCWCVD KYGNEIAGSR KQGTVSCEEE QETSGDFGSG GSVVLLDDLE EEPEATKKDK
EGKVKIHVRA ANEDDEDEDD DKDDEIGYIW


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