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SPG11, spatacsin vesicle trafficking associated

 F7B7P4_CALJA            Unreviewed;      2437 AA.
F7B7P4;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
27-JUL-2011, sequence version 1.
30-AUG-2017, entry version 27.
SubName: Full=SPG11, spatacsin vesicle trafficking associated {ECO:0000313|Ensembl:ENSCJAP00000004371};
Name=SPG11 {ECO:0000313|Ensembl:ENSCJAP00000004371};
Callithrix jacchus (White-tufted-ear marmoset).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000004371, ECO:0000313|Proteomes:UP000008225};
[1] {ECO:0000313|Ensembl:ENSCJAP00000004371, ECO:0000313|Proteomes:UP000008225}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSCJAP00000004371}
IDENTIFICATION.
Ensembl;
Submitted (JUN-2011) to UniProtKB.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSCJAP00000004371}.
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EMBL; ACFV01040877; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACFV01040878; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACFV01040879; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACFV01040880; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACFV01040881; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACFV01040882; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACFV01040883; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ACFV01040884; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9483.ENSCJAP00000004371; -.
Ensembl; ENSCJAT00000004607; ENSCJAP00000004371; ENSCJAG00000002382.
eggNOG; KOG1884; Eukaryota.
eggNOG; ENOG410XR4T; LUCA.
GeneTree; ENSGT00390000016791; -.
InParanoid; F7B7P4; -.
OMA; TCHMEGI; -.
OrthoDB; EOG091G008H; -.
TreeFam; TF325171; -.
Proteomes; UP000008225; Chromosome 10.
GO; GO:0030424; C:axon; IEA:Ensembl.
GO; GO:0031410; C:cytoplasmic vesicle; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0030425; C:dendrite; IEA:Ensembl.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0005765; C:lysosomal membrane; IEA:Ensembl.
GO; GO:0005730; C:nucleolus; IEA:Ensembl.
GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
GO; GO:0045202; C:synapse; IEA:Ensembl.
GO; GO:0008088; P:axo-dendritic transport; IEA:Ensembl.
GO; GO:0048675; P:axon extension; IEA:Ensembl.
GO; GO:0007268; P:chemical synaptic transmission; IEA:Ensembl.
GO; GO:0090389; P:phagosome-lysosome fusion involved in apoptotic cell clearance; IEA:Ensembl.
GO; GO:0048489; P:synaptic vesicle transport; IEA:Ensembl.
GO; GO:0090659; P:walking behavior; IEA:Ensembl.
InterPro; IPR028103; Spatacsin.
InterPro; IPR028107; Spatacsin_C_dom.
PANTHER; PTHR13650; PTHR13650; 1.
Pfam; PF14649; Spatacsin_C; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000008225};
Reference proteome {ECO:0000313|Proteomes:UP000008225}.
DOMAIN 2090 2381 Spatacsin_C. {ECO:0000259|Pfam:PF14649}.
SEQUENCE 2437 AA; 278445 MW; 595FFCAB78F403BF CRC64;
MAAEEEVASA AAARTAVMGQ VLPMLLVRVP AEAMGQLGSR AQLHTQQEVL GSLTAAGSLQ
VLSLAPGSQG AGRCCLEGPF WHFVWEDSRN SSIPTDKPKL LALGENYELL IYEFNLKDGR
CDATILYSCS GEALQKLIED QDISISLLSL RILSFCNNTS LLFINKCIVL HIIFPERDAA
IRVLNCFTLP LPMQAVDTII DTQLCKGVLF VLSSLGWICI LVVVDGTYVA HVDLALHEED
KCNEHQQEPA KIFTSLKVSQ DLDVLVILSS SNSAVALNLH LYFRQHPGHL LCERTLEDLP
IQGPKGMDED DPVSSAYNMK QTKFSFQIDR SWKAQLSSLN ETIKNSKLKV SCCVPWFRDI
LHLESPESGN HSTSVPSWAF IPQDIMHRQY HFPQKDRAKT SDPGRPWKIM HISEQEEPLG
LKCVSVTGFT ALFTWEVERM GCTVALWDLE THGMQCFSLG RKCIPIDSSG DQQLCFVLSE
NGLSLILFGL TQDEFINRLM IHGSASTVDT LCHLNGWGRC SIPIHALEAG IENRQLDTVD
FFLKSKENLF SPSSQSSVPD QFDHFSSHLY LKNVEELIPA LDLLCSAIRG SYSEPQSKHF
SEQLLNLTLS FLNKQIKELF IHTEELDEYL QRGVNILTSY INELRTFMIK FPWKLTDAID
EYDVHENVPK VKESSIWEKL SFEEVIANAI LNNKIPEAQT FFRMNSHSAQ NLEELIGIGL
NLVFENLKKN NIKEASELLK NMGFDVKDQL LKICFYTTDK NIRNFLVEIL KEKNYFSEKE
KRTIDFVHQV EKLYLGHFQE HMQIQSFPRY WINEQDFFTH KSVLDSFLKY DCQDEFNKQE
HRIVLNWALW WDQLTQESIL LPKISPEEYK SYSPEALWRY LTARHDWLNI ILWIGEFQTQ
HSYASLPQSK WPLLTVDVIN QNTCCNNYMR NEILDKLARN GVFLASELED FECFLLRLSR
IGGIIQDTLP VQNYKTKEGW DFHSQFILYC LEHSLQHLLY VYLDCYKLSP ENCPFLEKKE
LHEAHPWFEF LVQCRQVASN LTDPKLIFQA SLANAHILIP TNQASVSSML LEGHTLLALA
TTMYAPGGVS QVVQNEENEN CMKKVDPQLL KMALTPYPKL KTALFPQCTP PSVLPSDITL
YHLIQSLSPF DPSRLFGWQS ANTLAIGDAW SHLPHFSSPD LVNKYAIVER LNFAYYLHHG
RPSFAFGTFL VQELIKSKNP KQLIQQVGNE AYVLGLSSFH IPSTGAACVC FLELLGLDSL
KLRVDMKVAN IILSYKCRNE DAQYSFIRES VAEKLSKLAD GEKATTEELL VLLEEGTWNS
IQQQEIMRLS SESSSQWALV VQFCRLHNMK LSISYLKECA KANDWLQFII HSQLHNYHPA
EVKSLIQYFS PVVQDHLRLA FENLPSVPTS KMDSNQVCNK SPEELQGSKE EMTDLFGILL
QSSEEPDYWH WLLVEAVKQQ APILSVLASC LQDASAVSCL CVWIITSVED SVAAEAMGHI
QDSIEDHAWN LEDLSVIWRT LLTRQKSKTL IRGFQLFFKD SPLLLVIEMY ELCMFFKNYK
EAEAKLLEFQ RSLEMLNTGA TKVHPVIPAM WLEDQVCFLL KLMLQQCKTQ YELGKLLQLF
VEREHLFSDG PDVKKLYVLC QILKDTSIAI NLIIITSYSI ENFQHECRSI LERLQTDGQF
ALARRVAELA ELPVDNLVIE EITQEMQTLK RIEQWSLKQA RIDFWKKCHE NFQKNSISSK
AASSFFSAQA YVACEHPTGR SSIEECHLLL TLAGHWLAQE DPVPLDKLEE LEKQIWLCRI
TQHTLRRNQE ETEPRFSRQI STSGELSFDS LASEFSFSKL AALNTSKYLE LNGLPSKEAC
KNRLDWKEQE SLNFLIGRLL DDGCVHEASR VCQYFHFYNR DVTLVLHCRA LASGEASVED
LHPEIHALLQ SAELPEEEEP DVPLRRVHST SSLDSQKFVT LPSNDEVVTN LEVLTSKCLH
GKNYCRQVLC LYDLAKELGC SYTDVAAQDG EVMLREILAS QQPDRCRRAQ AFISTQGLKP
DTVAELVAEE VTQELLTPSQ GTGHKQMFGP TEESQTFLQL IALCQDRTLV GMKLLDKISS
VPHGELSCTT ELLILAHHCF TMTCHMEGII RVLQAARMLT DNHLAPSEEY GLVVRLLTGI
GRYNEMTYIF DLLHKKHYFE VLMRKKLDPS GTLKTALLNY IKRCRPGDSE KHNMIALCFS
MCREIGENHE AAARIQLKLI ESQPWEDSLK DGHQLKQLLL KALTLMLDAA ESYAKDSCVR
QAQHCQRLTK LITLQIHFLN TGQNTMLINL GRHKLMDCIL ALPQFYQASI VAEAYDFVPD
WAEILYQQVI LKGDFNYLEE FKQQRLLKSS IFEEISKKYK QHQPTDTVTE NLKKLLTYCE
DIYLYYKLAY EHKFYEIVNV LLKDPQTGCC LRDMLAG


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