Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Secreted frizzled-related protein 1 (sFRP-1)

 SFRP1_MOUSE             Reviewed;         314 AA.
Q8C4U3; O08861; Q505A2; Q8R1J4;
15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
27-JUL-2011, sequence version 3.
05-DEC-2018, entry version 139.
RecName: Full=Secreted frizzled-related protein 1;
Flags: Precursor;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
STRAIN=C57BL/6J; TISSUE=Embryonic eye;
PubMed=9096311; DOI=10.1073/pnas.94.7.2859;
Rattner A., Hsieh J.-C., Smallwood P.M., Gilbert D.J., Copeland N.G.,
Jenkins N.A., Nathans J.;
"A family of secreted proteins contains homology to the cysteine-rich
ligand-binding domain of frizzled receptors.";
Proc. Natl. Acad. Sci. U.S.A. 94:2859-2863(1997).
STRAIN=C57BL/6J, and FVB/N; TISSUE=Brain, and Colon;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
STRAIN=C57BL/6J; TISSUE=Cerebellum;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
PubMed=9739103; DOI=10.1016/S0925-4773(98)00072-0;
Leimeister C., Bach A., Gessler M.;
"Developmental expression patterns of mouse sFRP genes encoding
members of the secreted frizzled related protein family.";
Mech. Dev. 75:29-42(1998).
PubMed=10640709; DOI=10.1016/S0925-4773(99)00236-1;
Jaspard B., Couffinhal T., Dufourcq P., Moreau C., Duplaa C.;
"Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart
Mech. Dev. 90:263-267(2000).
PubMed=15306229; DOI=10.1016/j.cardiores.2004.05.006;
Ezan J., Leroux L., Barandon L., Dufourcq P., Jaspard B., Moreau C.,
Allieres C., Daret D., Couffinhal T., Duplaa C.;
"FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway,
controls vascular cell proliferation in vitro and in vivo.";
Cardiovasc. Res. 63:731-738(2004).
PubMed=19188438; DOI=10.1128/MCB.01274-08;
Kwon H.S., Lee H.S., Ji Y., Rubin J.S., Tomarev S.I.;
"Myocilin is a modulator of Wnt signaling.";
Mol. Cell. Biol. 29:2139-2154(2009).
-!- FUNCTION: Soluble frizzled-related proteins (sFRPS) function as
modulators of Wnt signaling through direct interaction with Wnts.
They have a role in regulating cell growth and differentiation in
specific cell types. SFRP1 decreases intracellular beta-catenin
levels (By similarity). Has antiproliferative effects on vascular
cells, in vitro and in vivo, and can induce, in vivo, an
angiogenic response. In vascular cell cycle, delays the G1 phase
and entry into the S phase. In kidney development, inhibits tubule
formation and bud growth in metanephroi (By similarity). Inhibits
WNT1/WNT4-mediated TCF-dependent transcription (By similarity).
{ECO:0000250, ECO:0000269|PubMed:15306229}.
-!- SUBUNIT: Interacts with WNT8, WNT1, WNT2, WNT4 and FRZD6 (By
similarity). Interacts with MYOC. {ECO:0000250,
ECO:0000269|PubMed:10640709, ECO:0000269|PubMed:19188438}.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Note=Cell membrane
or extracellular matrix-associated. Released by heparin-binding
(By similarity). {ECO:0000250}.
-!- TISSUE SPECIFICITY: Highly expressed in kidney and embryonic
heart. Also highly expressed in the eye, where it is principally
localized to the ciliary body and the lens epithelium. Weaker
expression in heart, lung and brain. In the brain, is expressed
exclusively in the choroid plexus. {ECO:0000269|PubMed:9096311}.
-!- DEVELOPMENTAL STAGE: In the developing kidney expressed at 13.5
dpc in the periphery of the metanophros and surrounding the uretic
and nephrogenic tubules. At 14.5 dpc, expression decreases in the
outer cortical cells and becomes visible in the tubular parts of
the nephron. From 15.5 dpc, highly expressed in the future loops
of Henle. In the developing CNS, expression located to the
forebrain and hindbrain. At 8.0 dpc, expressed in the future
forebrain and in the ventral portion of the presumptive hindbrain.
At 8.5 dpc, expression is maintained in these tissues with a
strong signal in rhombomere 4. Until 11.5 dpc, expression
continues in the hindbrain with additional expression at 9.5 dpc
and 10.5 dpc, in the nasal and epibranchial placodes. In the
forbrain, initial expression is found in the proencephalon of the
forebrain, and then strong expression in the telencephalic vesicle
up to 15.5 dpc. Expression is then found in specific cell
populations throughout the brain. In the developing eye,
expression, by 10.5 dpc, is confined to ectodermal cells overlying
the dorsal part of the optic cup. In later stages, expression
limited to the lens fiber cells and the future pigmented retina.
By 15.5 dpc, expression is confined to the anterior part of the
lens. During limb development, barely expressed until later
stages, when it is found in the distal part of the separating
phalanges. In other developing structures, expressed in nasal
placodes at 9.5 dpc, in medial nasal processes at E10.5 and then
in the anterior portion of the invaginating olfactory epithelium.
At 15.5 dpc, expressed on the basal side of the nasal epithelium.
Also expressed in developing teeth, with the highest levels at
15.5 dpc and 16.5 dpc in the mesenchyme and the dental epithelium
of the developing molars. As well, expressed in the ventral body
wall, in the mesenchyme derived adrenal cortex, the cochlear
epithelium and the branching epithelium of the salivary gland. In
the developing heart, weakly expressed from 8.5 dpc in the tubular
heart endocardium and myocardium. From 8.5 dpc to 12.5 dpc
expressed in cardiomyocytes. At 9.5 dpc, expression found in the
common ventricular and atrial chamber of the developing heart, in
the aortic sac and in the sinus venosus. High expression found
from 11.5 dpc-12.5 dpc, in the trabeculated wall of the
ventricular chamber together with the wall of the atrial chamber.
Expression also found in the muscular part of the interventricular
septum. From 9.5 dpc-11.5 dpc expression in the visceral yolk sac
confined to the inner lining endothelial cell layer. Expression in
the developing heart decreases after 14.5 dpc.
{ECO:0000269|PubMed:10640709, ECO:0000269|PubMed:9739103}.
-!- DOMAIN: The FZ domain is involved in binding with Wnt ligands.
-!- SIMILARITY: Belongs to the secreted frizzled-related protein
(sFRP) family. {ECO:0000305}.
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
EMBL; U88566; AAC53145.1; -; mRNA.
EMBL; BC024495; AAH24495.1; -; mRNA.
EMBL; BC094662; AAH94662.1; -; mRNA.
EMBL; AK081052; BAC38123.1; -; mRNA.
CCDS; CCDS22191.1; -.
RefSeq; NP_038862.2; NM_013834.3.
RefSeq; XP_011240430.1; XM_011242128.1.
UniGene; Mm.281691; -.
ProteinModelPortal; Q8C4U3; -.
SMR; Q8C4U3; -.
BioGrid; 203185; 7.
STRING; 10090.ENSMUSP00000033952; -.
ChEMBL; CHEMBL1075304; -.
MEROPS; I93.002; -.
iPTMnet; Q8C4U3; -.
PhosphoSitePlus; Q8C4U3; -.
MaxQB; Q8C4U3; -.
PaxDb; Q8C4U3; -.
PeptideAtlas; Q8C4U3; -.
PRIDE; Q8C4U3; -.
Ensembl; ENSMUST00000033952; ENSMUSP00000033952; ENSMUSG00000031548.
GeneID; 20377; -.
KEGG; mmu:20377; -.
UCSC; uc009lev.2; mouse.
CTD; 6422; -.
MGI; MGI:892014; Sfrp1.
eggNOG; KOG3577; Eukaryota.
GeneTree; ENSGT00940000159875; -.
HOGENOM; HOG000231058; -.
HOVERGEN; HBG052928; -.
InParanoid; Q8C4U3; -.
KO; K02166; -.
OrthoDB; EOG091G0F7I; -.
TreeFam; TF350133; -.
ChiTaRS; Sfrp1; mouse.
PRO; PR:Q8C4U3; -.
Proteomes; UP000000589; Chromosome 8.
Bgee; ENSMUSG00000031548; Expressed in 325 organ(s), highest expression level in epithelium of lens.
CleanEx; MM_SFRP1; -.
Genevisible; Q8C4U3; MM.
GO; GO:0009986; C:cell surface; ISO:MGI.
GO; GO:0062023; C:collagen-containing extracellular matrix; ISO:MGI.
GO; GO:0005829; C:cytosol; ISO:MGI.
GO; GO:0005615; C:extracellular space; HDA:BHF-UCL.
GO; GO:0005886; C:plasma membrane; ISO:MGI.
GO; GO:0004197; F:cysteine-type endopeptidase activity; ISO:MGI.
GO; GO:0008144; F:drug binding; ISO:MGI.
GO; GO:0005109; F:frizzled binding; ISO:MGI.
GO; GO:0008201; F:heparin binding; ISO:MGI.
GO; GO:0042802; F:identical protein binding; ISO:MGI.
GO; GO:0017147; F:Wnt-protein binding; ISO:MGI.
GO; GO:0030036; P:actin cytoskeleton organization; ISO:MGI.
GO; GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.
GO; GO:0060346; P:bone trabecula formation; IMP:MGI.
GO; GO:0060070; P:canonical Wnt signaling pathway; ISO:MGI.
GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
GO; GO:0071391; P:cellular response to estrogen stimulus; IDA:UniProtKB.
GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; ISO:MGI.
GO; GO:0071363; P:cellular response to growth factor stimulus; ISO:MGI.
GO; GO:0071504; P:cellular response to heparin; ISO:MGI.
GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
GO; GO:0071380; P:cellular response to prostaglandin E stimulus; IEA:Ensembl.
GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
GO; GO:0071356; P:cellular response to tumor necrosis factor; ISO:MGI.
GO; GO:0071305; P:cellular response to vitamin D; IEA:Ensembl.
GO; GO:0071481; P:cellular response to X-ray; IDA:UniProtKB.
GO; GO:0090246; P:convergent extension involved in somitogenesis; IGI:MGI.
GO; GO:0046546; P:development of primary male sexual characteristics; IGI:MGI.
GO; GO:0048546; P:digestive tract morphogenesis; IGI:MGI.
GO; GO:0071542; P:dopaminergic neuron differentiation; IDA:ParkinsonsUK-UCL.
GO; GO:0009950; P:dorsal/ventral axis specification; ISO:MGI.
GO; GO:0008585; P:female gonad development; IGI:MGI.
GO; GO:0002244; P:hematopoietic progenitor cell differentiation; ISO:MGI.
GO; GO:0060218; P:hematopoietic stem cell differentiation; ISO:MGI.
GO; GO:0030097; P:hemopoiesis; IMP:MGI.
GO; GO:0008584; P:male gonad development; IGI:MGI.
GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; ISO:MGI.
GO; GO:0043066; P:negative regulation of apoptotic process; ISO:MGI.
GO; GO:0045578; P:negative regulation of B cell differentiation; IMP:UniProtKB.
GO; GO:0030514; P:negative regulation of BMP signaling pathway; IGI:MGI.
GO; GO:0046851; P:negative regulation of bone remodeling; ISO:MGI.
GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
GO; GO:2000080; P:negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation; ISO:MGI.
GO; GO:0030308; P:negative regulation of cell growth; ISO:MGI.
GO; GO:0030336; P:negative regulation of cell migration; ISO:MGI.
GO; GO:0008285; P:negative regulation of cell proliferation; ISO:MGI.
GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISO:MGI.
GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; ISO:MGI.
GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; ISO:MGI.
GO; GO:0048147; P:negative regulation of fibroblast proliferation; ISO:MGI.
GO; GO:0010629; P:negative regulation of gene expression; IMP:MGI.
GO; GO:0046676; P:negative regulation of insulin secretion; ISO:MGI.
GO; GO:0043508; P:negative regulation of JUN kinase activity; IGI:MGI.
GO; GO:0030279; P:negative regulation of ossification; IMP:MGI.
GO; GO:0045668; P:negative regulation of osteoblast differentiation; IMP:MGI.
GO; GO:0033689; P:negative regulation of osteoblast proliferation; IMP:MGI.
GO; GO:0045671; P:negative regulation of osteoclast differentiation; IMP:MGI.
GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISO:MGI.
GO; GO:2000041; P:negative regulation of planar cell polarity pathway involved in axis elongation; IGI:MGI.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISO:MGI.
GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IGI:MGI.
GO; GO:2000054; P:negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; ISO:MGI.
GO; GO:0014034; P:neural crest cell fate commitment; IMP:MGI.
GO; GO:0001843; P:neural tube closure; IGI:MGI.
GO; GO:0021915; P:neural tube development; IGI:MGI.
GO; GO:0035567; P:non-canonical Wnt signaling pathway; IBA:GO_Central.
GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IGI:MGI.
GO; GO:0043065; P:positive regulation of apoptotic process; ISO:MGI.
GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISO:MGI.
GO; GO:0030307; P:positive regulation of cell growth; ISO:MGI.
GO; GO:0008284; P:positive regulation of cell proliferation; ISO:MGI.
GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISO:MGI.
GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:MGI.
GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; ISO:MGI.
GO; GO:0045600; P:positive regulation of fat cell differentiation; ISO:MGI.
GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; ISO:MGI.
GO; GO:2000052; P:positive regulation of non-canonical Wnt signaling pathway; ISO:MGI.
GO; GO:0045880; P:positive regulation of smoothened signaling pathway; ISO:MGI.
GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISO:MGI.
GO; GO:0030177; P:positive regulation of Wnt signaling pathway; ISO:MGI.
GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IMP:MGI.
GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IMP:MGI.
GO; GO:0010564; P:regulation of cell cycle process; ISO:MGI.
GO; GO:0090175; P:regulation of establishment of planar polarity; IGI:MGI.
GO; GO:1904956; P:regulation of midbrain dopaminergic neuron differentiation; IGI:ParkinsonsUK-UCL.
GO; GO:0010975; P:regulation of neuron projection development; IDA:ParkinsonsUK-UCL.
GO; GO:0030278; P:regulation of ossification; ISO:MGI.
GO; GO:0042493; P:response to drug; IDA:UniProtKB.
GO; GO:0014070; P:response to organic cyclic compound; ISO:MGI.
GO; GO:0035019; P:somatic stem cell population maintenance; IMP:MGI.
GO; GO:0001756; P:somitogenesis; IGI:MGI.
GO; GO:0044345; P:stromal-epithelial cell signaling involved in prostate gland development; IEP:UniProtKB.
GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISO:MGI.
GO; GO:0001657; P:ureteric bud development; IEP:UniProtKB.
GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IGI:MGI.
GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IDA:MGI.
Gene3D; 1.10.2000.10; -; 1.
InterPro; IPR015526; Frizzled/SFRP.
InterPro; IPR020067; Frizzled_dom.
InterPro; IPR036790; Frizzled_dom_sf.
InterPro; IPR001134; Netrin_domain.
InterPro; IPR018933; Netrin_module_non-TIMP.
InterPro; IPR026559; SFRP1.
InterPro; IPR008993; TIMP-like_OB-fold.
PANTHER; PTHR11309; PTHR11309; 1.
PANTHER; PTHR11309:SF87; PTHR11309:SF87; 1.
Pfam; PF01392; Fz; 1.
Pfam; PF01759; NTR; 1.
SMART; SM00643; C345C; 1.
SMART; SM00063; FRI; 1.
SUPFAM; SSF50242; SSF50242; 1.
SUPFAM; SSF63501; SSF63501; 1.
PROSITE; PS50038; FZ; 1.
PROSITE; PS50189; NTR; 1.
1: Evidence at protein level;
Complete proteome; Developmental protein; Differentiation;
Disulfide bond; Glycoprotein; Reference proteome; Secreted; Signal;
Wnt signaling pathway.
SIGNAL 1 31 {ECO:0000255}.
CHAIN 32 314 Secreted frizzled-related protein 1.
DOMAIN 53 169 FZ. {ECO:0000255|PROSITE-
DOMAIN 186 306 NTR. {ECO:0000255|PROSITE-
CARBOHYD 173 173 N-linked (GlcNAc...) asparagine.
DISULFID 58 121 {ECO:0000250}.
DISULFID 68 114 {ECO:0000250}.
DISULFID 105 140 {ECO:0000250}.
DISULFID 129 166 {ECO:0000250}.
DISULFID 133 157 {ECO:0000250}.
DISULFID 186 256 {ECO:0000250}.
DISULFID 189 258 {ECO:0000250}.
DISULFID 203 306 {ECO:0000250}.
CONFLICT 28 28 A -> S (in Ref. 2; AAH24495).
CONFLICT 245 245 R -> A (in Ref. 1; AAC53145).
SEQUENCE 314 AA; 35413 MW; 3D98A15127DFA421 CRC64;

Related products :

Catalog number Product name Quantity
EIAAB38042 Frizzled-related protein 1b,FRP1B,FRP-1b,Homo sapiens,Human,SARP3,SARP-3,Secreted apoptosis-related protein 3,Secreted frizzled-related protein 5,SFRP5,sFRP-5
18-003-43293 Secreted frizzled-related protein 1 - sFRP-1; Frizzled-related protein 1; FRP-1; Secreted apoptosis-related protein 2; SARP-2 Polyclonal 0.1 mg Protein A
18-001-30017 Secreted frizzled-related protein 5 - sFRP-5; Secreted apoptosis-related protein 3; SARP-3; Frizzled-related protein 1b; FRP-1b Polyclonal 0.1 mg
EIAAB38026 FRP,FRP1,FRP-1,Homo sapiens,Human,SARP2,SARP-2,Secreted apoptosis-related protein 2,Secreted frizzled-related protein 1,SFRP1,sFRP-1
EIAAB38032 FKSG12,FRP2,FRP-2,Homo sapiens,Human,SARP1,SARP-1,Secreted apoptosis-related protein 1,Secreted frizzled-related protein 2,SFRP2,sFRP-2,UNQ361_PRO697
EIAAB38036 FIZ,FRE,Frezzled,Fritz,Frizzled-related protein 1,FRP,FRZB,FRZB1,FrzB-1,Homo sapiens,Human,Secreted frizzled-related protein 3,SFRP3,sFRP-3
bs-1331P Peptides: sFRP-4(Secreted frizzled-related protein 4; Frizzled protein, human endometrium) Protein Length:12-25 amino acids. 200ug lyophilized
EIAAB38038 Fiz,Fre,Frezzled,Fritz,Frizzled-related protein 1,Frzb,Frzb1,FrzB-1,Mouse,Mus musculus,Secreted frizzled-related protein 3,Sfrp3,sFRP-3
EIAAB38031 Mouse,Mus musculus,Protein SDF5,Sarp1,SARP-1,Sdf5,Secreted apoptosis-related protein 1,Secreted frizzled-related protein 2,Sfrp2,sFRP-2
C640 Secreted Frizzled-Related Protein 2 sFRP-2 500
C640 Secreted Frizzled-Related Protein 2 sFRP-2 lmg
EIAAB38037 Bos taurus,Bovine,Frizzled-related protein 1,FRZB,FRZB1,FrzB-1,Secreted frizzled-related protein 3,SFRP3,sFRP-3
CC82 Human Secreted Frizzled-Related Protein 2 sFRP-2 50
C544 Human Secreted Frizzled-Related Protein 2 sFRP-2 l0
31-085 Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble m 0.1 mg
EIAAB38028 Mouse,Mus musculus,Secreted frizzled-related protein 1,Sfrp1,sFRP-1
EIAAB38029 Rat,Rattus norvegicus,Secreted frizzled-related protein 1,Sfrp1,sFRP-1
EIAAB38044 Bos taurus,Bovine,Secreted frizzled-related protein 5,SFRP5,sFRP-5
EIAAB38043 Mouse,Mus musculus,Secreted frizzled-related protein 5,Sfrp5,sFRP-5
C640 Recombinant Human Secreted Frizzled-Related Protein 2 per sFRP-2 per SARP1 (C-6His) 10ug
EIAAB38039 FRP-4,Mouse,Mus musculus,Secreted frizzled-related sequence protein 4,Sfrp4,sFRP-4
EIAAB38027 Bos taurus,Bovine,Frizzled in aorta protein,FRZA,FrzA protein,Secreted frizzled-related protein 1,SFRP1,sFRP-1
EIAAB38040 Ddc4,DDC-4 protein,Frp,Rat,Rattus norvegicus,Secreted frizzled-related protein 4,Sfrp4,sFRP-4
EIAAB38035 Chicken,Frizzled-related protein 1,FRZB,FrzB-1,Gallus gallus,Secreted frizzled-related protein 3,SFRP3,sFRP-3
EIAAB38041 Frizzled protein, human endometrium,FrpHE,FRPHE,Homo sapiens,Human,Secreted frizzled-related protein 4,SFRP4,sFRP-4


GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur

Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur



9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123

GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U

spain@gentaur.com | Gentaur | Gentaur

ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636

GENTAUR Poland Sp. z o.o.

ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556


Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur