Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Serine/arginine repetitive matrix protein 4 (Neural-specific serine/arginine repetitive splicing factor of 100 kDa) (Neural-specific SR-related protein of 100 kDa) (nSR100)

 SRRM4_MOUSE             Reviewed;         608 AA.
Q8BKA3; Q8R1S5; Q9CW37;
04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
01-MAR-2003, sequence version 1.
28-FEB-2018, entry version 100.
RecName: Full=Serine/arginine repetitive matrix protein 4;
AltName: Full=Neural-specific serine/arginine repetitive splicing factor of 100 kDa;
Short=Neural-specific SR-related protein of 100 kDa;
Short=nSR100;
Name=Srrm4;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
STRAIN=C57BL/6J; TISSUE=Cerebellum, and Eye;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
STRAIN=C57BL/6J, and FVB/N; TISSUE=Brain, and Liver;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[3]
FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, RNA-BINDING, AND
PHOSPHORYLATION.
PubMed=19737518; DOI=10.1016/j.cell.2009.06.012;
Calarco J.A., Superina S., O'Hanlon D., Gabut M., Raj B., Pan Q.,
Skalska U., Clarke L., Gelinas D., van der Kooy D., Zhen M.,
Ciruna B., Blencowe B.J.;
"Regulation of vertebrate nervous system alternative splicing and
development by an SR-related protein.";
Cell 138:898-910(2009).
-!- FUNCTION: Splicing factor specifically required for neural cell
differentiation. Acts in conjunction with nPTB/PTBP2 by binding
directly to its regulated target transcripts and promotes neural-
specific exon inclusion in many genes that function in neural cell
differentiation. Required to promote the inclusion of neural-
specific exon 10 in nPTB/PTBP2, leading to increased expression of
neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16
in DAAM1 in neuron extracts. {ECO:0000269|PubMed:19737518}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19737518}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1;
IsoId=Q8BKA3-1; Sequence=Displayed;
Name=2;
IsoId=Q8BKA3-2; Sequence=VSP_029639;
-!- TISSUE SPECIFICITY: Specifically expressed in neuronal cells (at
protein level). Expressed in adult nervous system and sensory
organ tissues. {ECO:0000269|PubMed:19737518}.
-!- PTM: Phosphorylated. {ECO:0000269|PubMed:19737518}.
-!- SIMILARITY: Belongs to the nSR100 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AK005085; BAB23809.1; -; mRNA.
EMBL; AK053836; BAC35548.1; -; mRNA.
EMBL; BC024130; AAH24130.1; -; mRNA.
EMBL; BC056392; AAH56392.1; -; mRNA.
CCDS; CCDS19601.1; -. [Q8BKA3-1]
RefSeq; NP_081162.1; NM_026886.3. [Q8BKA3-1]
RefSeq; XP_006530519.1; XM_006530456.3. [Q8BKA3-1]
UniGene; Mm.146779; -.
ProteinModelPortal; Q8BKA3; -.
STRING; 10090.ENSMUSP00000075488; -.
iPTMnet; Q8BKA3; -.
PhosphoSitePlus; Q8BKA3; -.
PaxDb; Q8BKA3; -.
PRIDE; Q8BKA3; -.
Ensembl; ENSMUST00000076124; ENSMUSP00000075488; ENSMUSG00000063919. [Q8BKA3-1]
Ensembl; ENSMUST00000139425; ENSMUSP00000144367; ENSMUSG00000063919. [Q8BKA3-2]
GeneID; 68955; -.
KEGG; mmu:68955; -.
UCSC; uc008zfb.1; mouse. [Q8BKA3-2]
UCSC; uc008zfc.1; mouse. [Q8BKA3-1]
CTD; 84530; -.
MGI; MGI:1916205; Srrm4.
eggNOG; ENOG410IEGN; Eukaryota.
eggNOG; ENOG4112C96; LUCA.
GeneTree; ENSGT00730000111247; -.
HOGENOM; HOG000013098; -.
InParanoid; Q8BKA3; -.
OMA; CESRHRG; -.
OrthoDB; EOG091G0FNP; -.
PhylomeDB; Q8BKA3; -.
PRO; PR:Q8BKA3; -.
Proteomes; UP000000589; Chromosome 5.
Bgee; ENSMUSG00000063919; -.
CleanEx; MM_1500001A10RIK; -.
ExpressionAtlas; Q8BKA3; baseline and differential.
Genevisible; Q8BKA3; MM.
GO; GO:0005634; C:nucleus; IDA:UniProtKB.
GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
GO; GO:0030154; P:cell differentiation; IMP:UniProtKB.
GO; GO:0006397; P:mRNA processing; IDA:UniProtKB.
GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:MGI.
GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
GO; GO:0007605; P:sensory perception of sound; IMP:MGI.
InterPro; IPR029360; SRRM_C.
Pfam; PF15230; SRRM_C; 1.
1: Evidence at protein level;
Alternative splicing; Complete proteome; Differentiation;
mRNA processing; mRNA splicing; Nucleus; Phosphoprotein;
Reference proteome; RNA-binding.
CHAIN 1 608 Serine/arginine repetitive matrix protein
4.
/FTId=PRO_0000311912.
COMPBIAS 109 171 Lys-rich.
COMPBIAS 123 605 Ser-rich.
COMPBIAS 404 593 Arg-rich.
VAR_SEQ 1 488 Missing (in isoform 2).
{ECO:0000303|PubMed:15489334}.
/FTId=VSP_029639.
SEQUENCE 608 AA; 67860 MW; 16DBEF71B68C301C CRC64;
MASLQQGEKQ LFEKFWKGTF KAVATPRPES IIVASITARK PMPRTEPQSS LLLPDQDGPS
EKLGQHLAPE ALGTNSWGRE KACRELDPAR AHSASQDRDP TPPPSSRGKK KKKKSTRKKR
RRSPSYSPSP VKKKKKKSSK KHKRHRSFSK KRRHSSCSPK SKRREEKRHK KQSRSRKSHR
HRHHRCPSRS QSSELRSPSC ESRHRGRSPE EGRKSRRTHS RRCSKNHCKV SPDARSSHLP
SQPLPRLGFL SARGVITGSG SAADLFSKSA SPLAATRGRS QEYDSGNDTS SPPSTQTSSA
RSRGQEKGSP GGDLSKSRDL NCGNTSDSGN SFTTSSPQNK GAVLETVSPA CRSRESRGFQ
SPCLQCAEVK KSSLVPSTAR SSPIKECSRS SSYTSTRSSS PSSRSPNPRA SPRYTRSRST
SSEKRSYSRS PSYSSKSGKR SPPSRSSRSR RSPSYSRYSP SRERDLKYGE KEPQPRERAR
RRRRSYSPMR KRRRDSPSHL EARRITSARK RPIPYYRPSP SSSSSLSSAS SWYSSSSSSS
SSSSRSPSRS YSRSRSPSRS HSSRSQTRSR TRTSRSSSSR SLSLGSRSRS RNRSLSYSSA
ESYASTRR


Related products :

Catalog number Product name Quantity
EIAAB39948 Mouse,Mus musculus,Neural-specific serine_arginine repetitive splicing factor of 100 kDa,Neural-specific SR-related protein of 100 kDa,nSR100,Serine_arginine repetitive matrix protein 4,Srrm4
EIAAB39947 Homo sapiens,Human,KIAA1853,Medulloblastoma antigen MU-MB-2.76,Neural-specific serine_arginine repetitive splicing factor of 100 kDa,Neural-specific SR-related protein of 100 kDa,nSR100,Serine_arginin
EIAAB39953 FUS-interacting serine-arginine-rich protein 1,Fusip1,Mouse,Mus musculus,Neural-salient serine_arginine-rich protein,Neural-specific SR protein,Nssr,Serine_arginine-rich splicing factor 10,Sfrs13a,Spl
E12522p Mouse ELISA Kit FOR Serine per arginine repetitive matrix protein 3 96T
E1905h Human ELISA Kit FOR Serine per arginine repetitive matrix protein 4 96T
SRRM2_HUMAN Human ELISA Kit FOR Serine per arginine repetitive matrix protein 2 96T
SRRM4_MOUSE Mouse ELISA Kit FOR Serine per arginine repetitive matrix protein 4 96T
E1799r Human ELISA Kit FOR Serine per arginine repetitive matrix protein 5 96T
SRRM1_HUMAN Human ELISA Kit FOR Serine per arginine repetitive matrix protein 1 96T
G9767 Serine arginine repetitive matrix protein 4 (KIAA1853), Human, ELISA Kit 96T
G9766 Serine arginine repetitive matrix protein 2 (SRRM2), Mouse, ELISA Kit 96T
G9765 Serine arginine repetitive matrix protein 2 (SRRM2), Human, ELISA Kit 96T
G9762 Serine arginine repetitive matrix protein 1 (SRRM1), Chicken, ELISA Kit 96T
G9764 Serine arginine repetitive matrix protein 1 (SRRM1), Mouse, ELISA Kit 96T
G9763 Serine arginine repetitive matrix protein 1 (SRRM1), Human, ELISA Kit 96T
SRRM2_MOUSE ELISA Kit FOR Serine per arginine repetitive matrix protein 2; organism: Mouse; gene name: Srrm2 96T
SRRM3_MOUSE ELISA Kit FOR Serine per arginine repetitive matrix protein 3; organism: Mouse; gene name: Srrm3 96T
SRRM4_MOUSE ELISA Kit FOR Serine per arginine repetitive matrix protein 4; organism: Mouse; gene name: Srrm4 96T
SRRM1_MOUSE ELISA Kit FOR Serine per arginine repetitive matrix protein 1; organism: Mouse; gene name: Srrm1 96T
EIAAB39954 40 kDa SR-repressor protein,FUS-interacting serine-arginine-rich protein 1,FUSIP1,FUSIP2,Homo sapiens,Human,Serine_arginine-rich splicing factor 10,SFRS13A,Splicing factor SRp38,Splicing factor, argin
EIAAB39943 300 kDa nuclear matrix antigen,Homo sapiens,HSPC075,Human,KIAA0324,Ser_Arg-related nuclear matrix protein of 300 kDa,Serine_arginine repetitive matrix protein 2,Serine_arginine-rich splicing factor-re
EIAAB38025 Homo sapiens,Human,SCAF,SCAF1,Serine arginine-rich pre-mRNA splicing factor SR-A1,SFRS19,Splicing factor, arginine_serine-rich 19,SRA1,SR-A1,SR-related and CTD-associated factor 1,SR-related-CTD-assoc
18-003-43665 FUS-interacting serine-arginine-rich protein 1 - TLS-associated protein with Ser-Arg repeats; TLS-associated protein with SR repeats; TASR; TLS-associated serine-arginine protein; TLS-associated SR pr 0.05 mg Aff Pur
PR-774 ASF per SF2 (SFRS1 or SRp30a)His Splicing Factor, Arginine per Serine-rich 1, Pre-mRNA Splicing Factor human, recombinant, E. coli 10
PR-775 ASF per SF2 (SFRS1 or SRp30a)His Splicing Factor, Arginine per Serine-rich 1, Pre-mRNA Splicing Factor human, recombinant, Sf9 insect cells 5


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur