Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2)

 PON2_RAT                Reviewed;         354 AA.
Q6AXM8;
19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
13-SEP-2004, sequence version 1.
12-SEP-2018, entry version 99.
RecName: Full=Serum paraoxonase/arylesterase 2;
Short=PON 2;
EC=3.1.1.2;
EC=3.1.1.81;
AltName: Full=Aromatic esterase 2;
Short=A-esterase 2;
AltName: Full=Serum aryldialkylphosphatase 2;
Name=Pon2;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Lung;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
-!- FUNCTION: Capable of hydrolyzing lactones and a number of aromatic
carboxylic acid esters. {ECO:0000250}.
-!- CATALYTIC ACTIVITY: A phenyl acetate + H(2)O = a phenol + acetate.
-!- CATALYTIC ACTIVITY: An N-acyl-L-homoserine lactone + H(2)O = an N-
acyl-L-homoserine.
-!- COFACTOR:
Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250};
Note=Binds 2 calcium ions per subunit. {ECO:0000250};
-!- SUBUNIT: Homotrimer. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
protein {ECO:0000250}.
-!- PTM: Glycosylated. {ECO:0000250}.
-!- PTM: The signal sequence is not cleaved. {ECO:0000250}.
-!- SIMILARITY: Belongs to the paraoxonase family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; BC079462; AAH79462.1; -; mRNA.
RefSeq; NP_001013100.1; NM_001013082.1.
UniGene; Rn.1100; -.
ProteinModelPortal; Q6AXM8; -.
SMR; Q6AXM8; -.
STRING; 10116.ENSRNOP00000033943; -.
PaxDb; Q6AXM8; -.
PRIDE; Q6AXM8; -.
Ensembl; ENSRNOT00000036460; ENSRNOP00000033943; ENSRNOG00000009112.
GeneID; 296851; -.
KEGG; rno:296851; -.
UCSC; RGD:1309954; rat.
CTD; 5445; -.
RGD; 1309954; Pon2.
eggNOG; ENOG410IHDV; Eukaryota.
eggNOG; ENOG4111QK7; LUCA.
GeneTree; ENSGT00390000008932; -.
HOGENOM; HOG000252960; -.
HOVERGEN; HBG003604; -.
InParanoid; Q6AXM8; -.
KO; K01045; -.
OMA; PDNKYIY; -.
OrthoDB; EOG091G0AV9; -.
PhylomeDB; Q6AXM8; -.
TreeFam; TF322436; -.
Reactome; R-RNO-2142688; Synthesis of 5-eicosatetraenoic acids.
PRO; PR:Q6AXM8; -.
Proteomes; UP000002494; Chromosome 4.
Bgee; ENSRNOG00000009112; Expressed in 10 organ(s), highest expression level in lung.
Genevisible; Q6AXM8; RN.
GO; GO:0005576; C:extracellular region; IEA:InterPro.
GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:RGD.
GO; GO:0005764; C:lysosome; IDA:RGD.
GO; GO:0005739; C:mitochondrion; IDA:RGD.
GO; GO:0005634; C:nucleus; IDA:RGD.
GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
GO; GO:0102007; F:acyl-L-homoserine-lactone lactonohydrolase activity; IEA:UniProtKB-EC.
GO; GO:0004064; F:arylesterase activity; IBA:GO_Central.
GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0019439; P:aromatic compound catabolic process; IEA:Ensembl.
GO; GO:0006979; P:response to oxidative stress; IEP:RGD.
GO; GO:0009636; P:response to toxic substance; IBA:GO_Central.
Gene3D; 2.120.10.30; -; 1.
InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
InterPro; IPR002640; Arylesterase.
InterPro; IPR008364; Paraoxonase2.
Pfam; PF01731; Arylesterase; 1.
PRINTS; PR01785; PARAOXONASE.
PRINTS; PR01787; PARAOXONASE2.
2: Evidence at transcript level;
Calcium; Complete proteome; Disulfide bond; Glycoprotein; Hydrolase;
Membrane; Metal-binding; Reference proteome; Signal.
CHAIN 1 354 Serum paraoxonase/arylesterase 2.
/FTId=PRO_0000223289.
SIGNAL 1 ? Not cleaved. {ECO:0000255}.
ACT_SITE 114 114 Proton acceptor. {ECO:0000250}.
METAL 53 53 Calcium 1; catalytic. {ECO:0000250}.
METAL 54 54 Calcium 2. {ECO:0000250}.
METAL 116 116 Calcium 2; via carbonyl oxygen.
{ECO:0000250}.
METAL 167 167 Calcium 1; catalytic. {ECO:0000250}.
METAL 168 168 Calcium 2. {ECO:0000250}.
METAL 223 223 Calcium 1; catalytic. {ECO:0000250}.
METAL 268 268 Calcium 1; catalytic. {ECO:0000250}.
METAL 269 269 Calcium 1; catalytic. {ECO:0000250}.
CARBOHYD 254 254 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 269 269 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 323 323 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 42 352 {ECO:0000250}.
SEQUENCE 354 AA; 39617 MW; 69D77678C781859D CRC64;
MGRLVALSLL GIGLALLGER FLALRSRLKA SREVESVDLP NCRLIKGIET GAEDIDILPN
GLAFFSVGLK FPGLHSFAPD KPGGILMMDL KEEKPRALEL RVSWGFDLAS FNPHGISTFI
DDDDTVYLFV VNHPEFKNTV EIFKFQEEEN SLLHLKTIKH ELLPSVNDVI AVGPSHFYAT
NDHYFSDPFL KYLETYLNLR WANVVYYSPE EVKLVAEGFD SANGINISPD KKYVYVADIL
AHEIHVLEKQ PNMNLTQLKV LQLGTLVDNL SIDPSSGDIW VGCHPNGQKL FVYDPNHPPS
SEVLRIQNIL SEKPSVTTVY INNGSVLQGS SVATIYDRKL LVGTLYQRAL YCEL


Related products :

Catalog number Product name Quantity
10-663-45323 Paraoxonase-2 (PON2) Human - EC 3.1.1.2; EC 3.1.8.1; PON 2; Serum aryldialkylphosphatase 2; A-esterase 2; Aromatic esterase 2 N_A 1 mg
10-663-45323 Paraoxonase-2 (PON2) Human - EC 3.1.1.2; EC 3.1.8.1; PON 2; Serum aryldialkylphosphatase 2; A-esterase 2; Aromatic esterase 2 N_A 0.002 mg
10-663-45323 Paraoxonase-2 (PON2) Human - EC 3.1.1.2; EC 3.1.8.1; PON 2; Serum aryldialkylphosphatase 2; A-esterase 2; Aromatic esterase 2 N_A 0.01 mg
E0243h ELISA kit A-esterase 1,Aromatic esterase 1,Homo sapiens,Human,K-45,PON,PON 1,PON1,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
E0243h ELISA A-esterase 1,Aromatic esterase 1,Homo sapiens,Human,K-45,PON,PON 1,PON1,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
E0243Rb ELISA A-esterase 1,Aromatic esterase 1,Oryctolagus cuniculus,PON,PON 1,PON1,Rabbit,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
U0243h CLIA A-esterase 1,Aromatic esterase 1,Homo sapiens,Human,K-45,PON,PON 1,PON1,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
E0243Rb ELISA kit A-esterase 1,Aromatic esterase 1,Oryctolagus cuniculus,PON,PON 1,PON1,Rabbit,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
U0243Rb CLIA A-esterase 1,Aromatic esterase 1,Oryctolagus cuniculus,PON,PON 1,PON1,Rabbit,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
EIAAB31800 A-esterase 2,Aromatic esterase 2,Homo sapiens,Human,PON 2,PON2,Serum aryldialkylphosphatase 2,Serum paraoxonase_arylesterase 2
U0243m CLIA A-esterase 1,Aromatic esterase 1,Mouse,Mus musculus,Pon,PON 1,Pon1,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
E0243r ELISA kit A-esterase 1,Aromatic esterase 1,Pon,PON 1,Pon1,Rat,Rattus norvegicus,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
E0243m ELISA kit A-esterase 1,Aromatic esterase 1,Mouse,Mus musculus,Pon,PON 1,Pon1,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
E0243r ELISA A-esterase 1,Aromatic esterase 1,Pon,PON 1,Pon1,Rat,Rattus norvegicus,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
U0243r CLIA A-esterase 1,Aromatic esterase 1,Pon,PON 1,Pon1,Rat,Rattus norvegicus,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
E0243m ELISA A-esterase 1,Aromatic esterase 1,Mouse,Mus musculus,Pon,PON 1,Pon1,Serum aryldialkylphosphatase 1,Serum paraoxonase_arylesterase 1 96T
EIAAB31797 A-esterase 2,Aromatic esterase 2,Bos taurus,Bovine,PON 2,PON2,Serum aryldialkylphosphatase 2,Serum paraoxonase_arylesterase 2
EIAAB31798 A-esterase 2,Aromatic esterase 2,Mouse,Mus musculus,PON 2,Pon2,Serum aryldialkylphosphatase 2,Serum paraoxonase_arylesterase 2
EIAAB31799 A-esterase 2,Aromatic esterase 2,PON 2,Pon2,Rat,Rattus norvegicus,Serum aryldialkylphosphatase 2,Serum paraoxonase_arylesterase 2
EIAAB31802 A-esterase 2,Aromatic esterase 2,Chicken,Gallus gallus,PON 2,PON2,Serum aryldialkylphosphatase 2,Serum paraoxonase_arylesterase 2
EIAAB31801 A-esterase 2,Aromatic esterase 2,Canis familiaris,Canis lupus familiaris,Dog,PON 2,PON2,Serum aryldialkylphosphatase 2,Serum paraoxonase_arylesterase 2
orb21956 Goat Serum Against Human C1 Esterase Inhibitor Polyclonal Precipitating polyclonal goat antiserum to human C1 esterase inhibitor. C1 esterase inhibitor is a single chain acid glycoprotein with a molec 1 ml
ER265 Serum paraoxonase per arylesterase 1 Elisa Kit 96T
ER405 Serum paraoxonase per arylesterase 2 Elisa Kit 96T
EH1117 Serum paraoxonase per arylesterase 2 Elisa Kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur