Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Sodium/potassium/calcium exchanger 4 (Na( )/K( )/Ca(2 )-exchange protein 4) (Solute carrier family 24 member 4)

 NCKX4_HUMAN             Reviewed;         622 AA.
Q8NFF2; B4DHE7; B9ZVY2; Q8N8U6; Q8NCX1; Q8NFF0; Q8NFF1;
26-SEP-2003, integrated into UniProtKB/Swiss-Prot.
27-JUL-2011, sequence version 2.
22-NOV-2017, entry version 141.
RecName: Full=Sodium/potassium/calcium exchanger 4;
AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 4;
AltName: Full=Solute carrier family 24 member 4;
Flags: Precursor;
Name=SLC24A4 {ECO:0000312|HGNC:HGNC:10978}; Synonyms=NCKX4;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), AND NUCLEOTIDE SEQUENCE [MRNA]
OF 10-622 (ISOFORMS 1 AND 3).
PubMed=12379639; DOI=10.1074/jbc.M210011200;
Li X.-F., Kraev A.S., Lytton J.;
"Molecular cloning of a fourth member of the potassium-dependent
sodium-calcium exchanger gene family, NCKX4.";
J. Biol. Chem. 277:48410-48417(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), AND NUCLEOTIDE
SEQUENCE [LARGE SCALE MRNA] OF 1-474 (ISOFORM 4).
TISSUE=Brain;
PubMed=14702039; DOI=10.1038/ng1285;
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human
cDNAs.";
Nat. Genet. 36:40-45(2004).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=12508121; DOI=10.1038/nature01348;
Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
Quetier F., Waterston R., Hood L., Weissenbach J.;
"The DNA sequence and analysis of human chromosome 14.";
Nature 421:601-607(2003).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 10-622 (ISOFORM 1).
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 294-622 (ISOFORM 1).
TISSUE=Testis;
PubMed=17974005; DOI=10.1186/1471-2164-8-399;
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U.,
Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H.,
Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K.,
Ottenwaelder B., Poustka A., Wiemann S., Schupp I.;
"The full-ORF clone resource of the German cDNA consortium.";
BMC Genomics 8:399-399(2007).
[7]
INVOLVEMENT IN SHEP6, AND POLYMORPHISM.
PubMed=17952075; DOI=10.1038/ng.2007.13;
Sulem P., Gudbjartsson D.F., Stacey S.N., Helgason A., Rafnar T.,
Magnusson K.P., Manolescu A., Karason A., Palsson A., Thorleifsson G.,
Jakobsdottir M., Steinberg S., Palsson S., Jonasson F.,
Sigurgeirsson B., Thorisdottir K., Ragnarsson R.,
Benediktsdottir K.R., Aben K.K., Kiemeney L.A., Olafsson J.H.,
Gulcher J., Kong A., Thorsteinsdottir U., Stefansson K.;
"Genetic determinants of hair, eye and skin pigmentation in
Europeans.";
Nat. Genet. 39:1443-1452(2007).
[8]
INVOLVEMENT IN AI2A5, AND VARIANT AI2A5 CYS-499.
PubMed=23375655; DOI=10.1016/j.ajhg.2013.01.003;
Parry D.A., Poulter J.A., Logan C.V., Brookes S.J., Jafri H.,
Ferguson C.H., Anwari B.M., Rashid Y., Zhao H., Johnson C.A.,
Inglehearn C.F., Mighell A.J.;
"Identification of mutations in SLC24A4, encoding a potassium-
dependent sodium/calcium exchanger, as a cause of amelogenesis
imperfecta.";
Am. J. Hum. Genet. 92:307-312(2013).
[9]
INVOLVEMENT IN AI2A5, AND VARIANT AI2A5 VAL-146.
PubMed=24621671; DOI=10.1177/0022034514527971;
Wang S., Choi M., Richardson A.S., Reid B.M., Seymen F., Yildirim M.,
Tuna E., Gencay K., Simmer J.P., Hu J.C.;
"STIM1 and SLC24A4 are critical for enamel maturation.";
J. Dent. Res. 93:94S-100S(2014).
-!- FUNCTION: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Controls the rapid response termination and proper regulation of
adaptation in olfactory sensory neurons (OSNs) which subsequently
influences how odor information is encoded and perceived. May play
a role in calcium transport during amelogenesis (By similarity).
{ECO:0000250|UniProtKB:Q8CGQ8}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8CGQ8}.
Cell membrane {ECO:0000250|UniProtKB:Q8CGQ8}; Multi-pass membrane
protein {ECO:0000250|UniProtKB:Q8CGQ8}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=4;
Name=1;
IsoId=Q8NFF2-1; Sequence=Displayed;
Name=2;
IsoId=Q8NFF2-2; Sequence=VSP_008369;
Name=3;
IsoId=Q8NFF2-3; Sequence=VSP_008372;
Name=4;
IsoId=Q8NFF2-4; Sequence=VSP_008370, VSP_008371;
Note=No experimental confirmation available.;
-!- TISSUE SPECIFICITY: Expressed abundantly in all regions of the
brain, aorta, lung and thymus. Expressed at lower levels in the
stomach and intestine.
-!- POLYMORPHISM: Genetic variants in SLC24A4 define the skin/hair/eye
pigmentation variation locus 6 (SHEP6) [MIM:210750]. Hair, eye and
skin pigmentation are among the most visible examples of human
phenotypic variation, with a broad normal range that is subject to
substantial geographic stratification. In the case of skin,
individuals tend to have lighter pigmentation with increasing
distance from the equator. By contrast, the majority of variation
in human eye and hair color is found among individuals of European
ancestry, with most other human populations fixed for brown eyes
and black hair. {ECO:0000269|PubMed:17952075}.
-!- DISEASE: Amelogenesis imperfecta, hypomaturation type, 2A5 (AI2A5)
[MIM:615887]: A defect of enamel formation. The disorder involves
both primary and secondary dentitions. The teeth have a shiny agar
jelly appearance and the enamel is softer than normal. Brown
pigment is present in middle layers of enamel.
{ECO:0000269|PubMed:23375655, ECO:0000269|PubMed:24621671}.
Note=The disease is caused by mutations affecting the gene
represented in this entry.
-!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC
2.A.19) family. SLC24A subfamily. {ECO:0000305}.
-!- CAUTION: It is uncertain whether Met-1 or Met-18 is the initiator.
{ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=AAH69653.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Sequence=AAM76070.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Sequence=AAM76071.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Sequence=BAC04715.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};
Sequence=CAD38903.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AF520704; AAM76070.1; ALT_INIT; mRNA.
EMBL; AF520705; AAM76071.1; ALT_INIT; mRNA.
EMBL; AF520706; AAM76072.1; -; mRNA.
EMBL; AK096171; BAC04715.1; ALT_SEQ; mRNA.
EMBL; AK295059; BAG58108.1; -; mRNA.
EMBL; AL118559; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH471061; EAW81485.1; -; Genomic_DNA.
EMBL; BC069653; AAH69653.1; ALT_INIT; mRNA.
EMBL; AL834225; CAD38903.1; ALT_INIT; mRNA.
CCDS; CCDS45155.2; -. [Q8NFF2-3]
CCDS; CCDS45156.1; -. [Q8NFF2-2]
CCDS; CCDS9903.2; -. [Q8NFF2-1]
RefSeq; NP_705932.2; NM_153646.3. [Q8NFF2-1]
RefSeq; NP_705933.2; NM_153647.3. [Q8NFF2-3]
RefSeq; NP_705934.1; NM_153648.3. [Q8NFF2-2]
RefSeq; XP_011534743.1; XM_011536441.2.
RefSeq; XP_011534744.1; XM_011536442.2.
UniGene; Hs.385530; -.
ProteinModelPortal; Q8NFF2; -.
SMR; Q8NFF2; -.
STRING; 9606.ENSP00000431840; -.
TCDB; 2.A.19.4.5; the ca(2+):cation antiporter (caca) family.
iPTMnet; Q8NFF2; -.
PhosphoSitePlus; Q8NFF2; -.
BioMuta; SLC24A4; -.
DMDM; 341941166; -.
EPD; Q8NFF2; -.
PaxDb; Q8NFF2; -.
PeptideAtlas; Q8NFF2; -.
PRIDE; Q8NFF2; -.
Ensembl; ENST00000393265; ENSP00000376948; ENSG00000140090. [Q8NFF2-2]
Ensembl; ENST00000531433; ENSP00000433302; ENSG00000140090. [Q8NFF2-3]
Ensembl; ENST00000532405; ENSP00000431840; ENSG00000140090. [Q8NFF2-1]
GeneID; 123041; -.
KEGG; hsa:123041; -.
UCSC; uc001yai.4; human. [Q8NFF2-1]
CTD; 123041; -.
DisGeNET; 123041; -.
EuPathDB; HostDB:ENSG00000140090.17; -.
GeneCards; SLC24A4; -.
HGNC; HGNC:10978; SLC24A4.
MalaCards; SLC24A4; -.
MIM; 210750; phenotype.
MIM; 609840; gene.
MIM; 615887; phenotype.
neXtProt; NX_Q8NFF2; -.
OpenTargets; ENSG00000140090; -.
Orphanet; 100032; Hypocalcified amelogenesis imperfecta.
Orphanet; 100033; Hypomaturation amelogenesis imperfecta.
PharmGKB; PA35854; -.
eggNOG; KOG1307; Eukaryota.
eggNOG; ENOG410Y9YY; LUCA.
GeneTree; ENSGT00760000119209; -.
HOVERGEN; HBG054881; -.
InParanoid; Q8NFF2; -.
KO; K13752; -.
OMA; WRNRKLM; -.
OrthoDB; EOG091G0M5C; -.
PhylomeDB; Q8NFF2; -.
TreeFam; TF318759; -.
Reactome; R-HSA-425561; Sodium/Calcium exchangers.
Reactome; R-HSA-5619055; Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI).
GenomeRNAi; 123041; -.
PRO; PR:Q8NFF2; -.
Proteomes; UP000005640; Chromosome 14.
Bgee; ENSG00000140090; -.
CleanEx; HS_SLC24A4; -.
ExpressionAtlas; Q8NFF2; baseline and differential.
Genevisible; Q8NFF2; HS.
GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0016020; C:membrane; ISS:UniProtKB.
GO; GO:0005886; C:plasma membrane; TAS:Reactome.
GO; GO:0005262; F:calcium channel activity; IBA:GO_Central.
GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
GO; GO:0008273; F:calcium, potassium:sodium antiporter activity; IBA:GO_Central.
GO; GO:0030955; F:potassium ion binding; IBA:GO_Central.
GO; GO:0031402; F:sodium ion binding; IBA:GO_Central.
GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO; GO:0097186; P:amelogenesis; ISS:UniProtKB.
GO; GO:0006874; P:cellular calcium ion homeostasis; IBA:GO_Central.
GO; GO:0006811; P:ion transport; TAS:Reactome.
GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
GO; GO:0007608; P:sensory perception of smell; ISS:UniProtKB.
InterPro; IPR004481; K/Na/Ca-exchanger.
InterPro; IPR004837; NaCa_Exmemb.
InterPro; IPR030232; SLC24A4.
PANTHER; PTHR10846; PTHR10846; 1.
PANTHER; PTHR10846:SF21; PTHR10846:SF21; 1.
Pfam; PF01699; Na_Ca_ex; 2.
TIGRFAMs; TIGR00367; TIGR00367; 1.
1: Evidence at protein level;
Alternative splicing; Amelogenesis imperfecta; Antiport; Calcium;
Calcium transport; Cell membrane; Complete proteome; Cytoplasm;
Disease mutation; Glycoprotein; Ion transport; Membrane; Olfaction;
Polymorphism; Potassium; Potassium transport; Reference proteome;
Repeat; Sensory transduction; Signal; Sodium; Sodium transport;
Symport; Transmembrane; Transmembrane helix; Transport.
SIGNAL 1 38 {ECO:0000255}.
CHAIN 39 622 Sodium/potassium/calcium exchanger 4.
/FTId=PRO_0000019373.
TOPO_DOM 39 97 Extracellular. {ECO:0000305}.
TRANSMEM 98 118 Helical. {ECO:0000255}.
TOPO_DOM 119 142 Cytoplasmic. {ECO:0000305}.
TRANSMEM 143 163 Helical. {ECO:0000255}.
TOPO_DOM 164 172 Extracellular. {ECO:0000305}.
TRANSMEM 173 193 Helical. {ECO:0000255}.
TOPO_DOM 194 200 Cytoplasmic. {ECO:0000305}.
TRANSMEM 201 221 Helical. {ECO:0000255}.
TOPO_DOM 222 224 Extracellular. {ECO:0000305}.
TRANSMEM 225 245 Helical. {ECO:0000255}.
TOPO_DOM 246 457 Cytoplasmic. {ECO:0000305}.
TRANSMEM 458 478 Helical. {ECO:0000255}.
TOPO_DOM 479 479 Extracellular. {ECO:0000305}.
TRANSMEM 480 500 Helical. {ECO:0000255}.
TOPO_DOM 501 526 Cytoplasmic. {ECO:0000305}.
TRANSMEM 527 547 Helical. {ECO:0000255}.
TOPO_DOM 548 557 Extracellular. {ECO:0000305}.
TRANSMEM 558 578 Helical. {ECO:0000255}.
TOPO_DOM 579 586 Cytoplasmic. {ECO:0000305}.
TRANSMEM 587 607 Helical. {ECO:0000255}.
TOPO_DOM 608 622 Extracellular. {ECO:0000305}.
REPEAT 139 179 Alpha-1.
REPEAT 495 526 Alpha-2.
COMPBIAS 395 406 Poly-Pro.
CARBOHYD 69 69 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 76 76 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
VAR_SEQ 1 109 Missing (in isoform 4).
{ECO:0000303|PubMed:14702039}.
/FTId=VSP_008370.
VAR_SEQ 1 64 Missing (in isoform 2).
{ECO:0000303|PubMed:12379639}.
/FTId=VSP_008369.
VAR_SEQ 172 210 Missing (in isoform 4).
{ECO:0000303|PubMed:14702039}.
/FTId=VSP_008371.
VAR_SEQ 275 293 Missing (in isoform 3).
{ECO:0000303|PubMed:12379639,
ECO:0000303|PubMed:14702039}.
/FTId=VSP_008372.
VARIANT 146 146 A -> V (in AI2A5; autosomal recessive;
dbSNP:rs587777537).
{ECO:0000269|PubMed:24621671}.
/FTId=VAR_071475.
VARIANT 499 499 S -> C (in AI2A5; autosomal recessive;
dbSNP:rs587777536).
{ECO:0000269|PubMed:23375655}.
/FTId=VAR_070183.
VARIANT 613 613 V -> I (in dbSNP:rs4900130).
/FTId=VAR_042664.
CONFLICT 444 444 C -> S (in Ref. 2; BAC04715).
{ECO:0000305}.
CONFLICT 560 560 Y -> H (in Ref. 2; BAG58108).
{ECO:0000305}.
SEQUENCE 622 AA; 69042 MW; 00D69370E55EE388 CRC64;
MALRGTLRPL KVRRRREMLP QQVGFVCAVL ALVCCASGLF GSLGHKTASA SKRVLPDTWR
NRKLMAPVNG TQTAKNCTDP AIHEFPTDLF SNKERQHGAV LLHILGALYM FYALAIVCDD
FFVPSLEKIC ERLHLSEDVA GATFMAAGSS TPELFASVIG VFITHGDVGV GTIVGSAVFN
ILCIIGVCGL FAGQVVRLTW WAVCRDSVYY TISVIVLIVF IYDEQIVWWE GLVLIILYVF
YILIMKYNVK MQAFFTVKQK SIANGNPVNS ELEAGNDFYD GSYDDPSVPL LGQVKEKPQY
GKNPVVMVDE IMSSSPPKFT FPEAGLRIMI TNKFGPRTRL RMASRIIINE RQRLINSANG
VSSKPLQNGR HENIENGNVP VENPEDPQQN QEQQPPPQPP PPEPEPVEAD FLSPFSVPEA
RGDKVKWVFT WPLIFLLCVT IPNCSKPRWE KFFMVTFITA TLWIAVFSYI MVWLVTIIGY
TLGIPDVIMG ITFLAAGTSV PDCMASLIVA RQGLGDMAVS NTIGSNVFDI LVGLGVPWGL
QTMVVNYGST VKINSRGLVY SVVLLLGSVA LTVLGIHLNK WRLDRKLGVY VLVLYAIFLC
FSIMIEFNVF TFVNLPMCRE DD


Related products :

Catalog number Product name Quantity
E12412078 Rat Solute Carrier Family 8 (Sodium per calcium Exchanger), Member 1 (SLC8A1)ELISA Kit 1
EIAAB26540 Homo sapiens,Human,Na(+)_K(+)_Ca(2+)-exchange protein 2,NCKX2,Retinal cone Na-Ca+K exchanger,SLC24A2,Sodium_potassium_calcium exchanger 2,Solute carrier family 24 member 2
E1380130 Guinea pig Solute Carrier Family 8 (Sodium per calcium Exchanger), Member 1 (SLC8A1) ELISA Kit
E13832950 Chicken Solute Carrier Family 8 (Sodium per calcium Exchanger), Member 1 (SLC8A1)ELISA Kit
EIAAB26548 Mouse,Mus musculus,Na(+)_K(+)_Ca(2+)-exchange protein 5,Nckx5,Slc24a5,Sodium_potassium_calcium exchanger 5,Solute carrier family 24 member 5
EIAAB26550 Mouse,Mus musculus,Na(+)_K(+)_Ca(2+)-exchange protein 6,Nckx6,Slc24a6,Sodium_potassium_calcium exchanger 6,Solute carrier family 24 member 6
EIAAB26546 Homo sapiens,Human,Na(+)_K(+)_Ca(2+)-exchange protein 4,NCKX4,SLC24A4,Sodium_potassium_calcium exchanger 4,Solute carrier family 24 member 4
EIAAB26549 Homo sapiens,Human,JSX,Na(+)_K(+)_Ca(2+)-exchange protein 5,NCKX5,SLC24A5,Sodium_potassium_calcium exchanger 5,Solute carrier family 24 member 5
EIAAB26544 Homo sapiens,Human,Na(+)_K(+)_Ca(2+)-exchange protein 3,NCKX3,SLC24A3,Sodium_potassium_calcium exchanger 3,Solute carrier family 24 member 3
EIAAB26552 Na(+)_K(+)_Ca(2+)-exchange protein 6,Nckx6,Nclx,Rat,Rattus norvegicus,Slc24a6,Sodium_potassium_calcium exchanger 6,Solute carrier family 24 member 6
EIAAB26551 Homo sapiens,Human,Na(+)_K(+)_Ca(2+)-exchange protein 6,NCKX6,NCLX,SLC24A6,Sodium_potassium_calcium exchanger 6,Solute carrier family 24 member 6
EIAAB27170 Na(+)_H(+) exchange regulatory cofactor NHE-RF2,NHERF2,Oryctolagus cuniculus,PDZ domain-containing protein NHERF-2,Rabbit,SLC9A3R2,Sodium-hydrogen exchanger regulatory factor 2,Solute carrier family 9
EIAAB37102 Electroneutral Na+-driven Cl-HCO3 exchanger,Electroneutral sodium bicarbonate exchanger 1,Kiaa0739,k-NBC3,Mouse,Mus musculus,Slc4a8,Solute carrier family 4 member 8
EIAAB37103 Electroneutral Na+-driven Cl-HCO3 exchanger,Electroneutral sodium bicarbonate exchanger 1,k-NBC3,Ndcbe1,Rat,Rattus norvegicus,Slc4a8,Solute carrier family 4 member 8
GWB-FEFC12 Anti- SLC9A9 (solute carrier family 9 (sodium hydrogen exchanger). member 9) Antibody
EIAAB37165 Gm610,Mouse,Mus musculus,Na(+)_H(+) exchanger 10,NHE-10,Slc9a10,sNHE,Sodium_hydrogen exchanger 10,Solute carrier family 10 member 10,Sperm-specific Na(+)_H(+) exchanger
EIAAB37166 Homo sapiens,Human,Na(+)_H(+) exchanger 10,NHE-10,SLC9A10,sNHE,Sodium_hydrogen exchanger 10,Solute carrier family 9 member 10,Sperm-specific Na(+)_H(+) exchanger
EIAAB37088 Bos taurus,Bovine,SLC4A10,Sodium-driven chloride bicarbonate exchanger,Solute carrier family 4 member 10
EIAAB37086 Ncbe,Rat,Rattus norvegicus,Slc4a10,Sodium-driven chloride bicarbonate exchanger,Solute carrier family 4 member 10
EIAAB37104 Electroneutral Na(+)-driven Cl-HCO3 exchanger,Electroneutral sodium bicarbonate exchanger 1,Homo sapiens,Human,KIAA0739,k-NBC3,NBC,NBC3,NDCBE1,SLC4A8,Solute carrier family 4 member 8
GWB-AED125 Solute Carrier Family 9 (Sodium Hydrogen Exchanger) Member 9 (SLC9A9) Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
GWB-C757EC Solute Carrier Family 9 (Sodium Hydrogen Exchanger) Member 3 Regulator 1 (SLC9A3R1) Mouse anti-Human Monoclonal (EBP-10) Antibo
EIAAB37087 Kiaa4136,Mouse,Mus musculus,Ncbe,Slc4a10,Sodium-driven chloride bicarbonate exchanger,Solute carrier family 4 member 10
EIAAB37085 Homo sapiens,Human,NCBE,SLC4A10,Sodium-driven chloride bicarbonate exchanger,Solute carrier family 4 member 10
EIAAB38595 Na(+)_H(+) exchanger 1,NHE1,NHE-1,Pig,SLC9A1,Sodium_hydrogen exchanger 1,Solute carrier family 9 member 1,Sus scrofa


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur