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Sodium/potassium-transporting ATPase subunit beta

 H2PBM4_PONAB            Unreviewed;       265 AA.
H2PBM4;
21-MAR-2012, integrated into UniProtKB/TrEMBL.
09-JAN-2013, sequence version 2.
25-OCT-2017, entry version 36.
RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};
Name=ATP1B3 {ECO:0000313|Ensembl:ENSPPYP00000015848};
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Pongo.
NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000015848, ECO:0000313|Proteomes:UP000001595};
[1] {ECO:0000313|Ensembl:ENSPPYP00000015848, ECO:0000313|Proteomes:UP000001595}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Wilson R.K., Mardis E.;
"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSPPYP00000015848}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2012) to UniProtKB.
-!- FUNCTION: This is the non-catalytic component of the active
enzyme, which catalyzes the hydrolysis of ATP coupled with the
exchange of Na(+) and K(+) ions across the plasma membrane.
{ECO:0000256|RuleBase:RU362099}.
-!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362099}.
-!- SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta
family. {ECO:0000256|RuleBase:RU362099}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSPPYP00000015848}.
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EMBL; ABGA01120794; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01120795; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01120796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9601.ENSPPYP00000015848; -.
Ensembl; ENSPPYT00000016475; ENSPPYP00000015848; ENSPPYG00000014169.
eggNOG; KOG3927; Eukaryota.
eggNOG; ENOG411150A; LUCA.
GeneTree; ENSGT00550000074530; -.
InParanoid; H2PBM4; -.
OMA; SITINCE; -.
OrthoDB; EOG091G0DJ4; -.
TreeFam; TF314618; -.
Proteomes; UP000001595; Chromosome 3.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:Ensembl.
GO; GO:0001671; F:ATPase activator activity; IEA:Ensembl.
GO; GO:0051117; F:ATPase binding; IEA:Ensembl.
GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; IEA:Ensembl.
GO; GO:0030007; P:cellular potassium ion homeostasis; IEA:Ensembl.
GO; GO:0006883; P:cellular sodium ion homeostasis; IEA:Ensembl.
GO; GO:0086009; P:membrane repolarization; IEA:Ensembl.
GO; GO:1903288; P:positive regulation of potassium ion import; IEA:Ensembl.
GO; GO:1901018; P:positive regulation of potassium ion transmembrane transporter activity; IEA:Ensembl.
GO; GO:1903278; P:positive regulation of sodium ion export from cell; IEA:Ensembl.
GO; GO:0010107; P:potassium ion import; IEA:Ensembl.
GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
GO; GO:0036376; P:sodium ion export from cell; IEA:Ensembl.
InterPro; IPR000402; Na/K_ATPase_sub_beta.
PANTHER; PTHR11523; PTHR11523; 1.
Pfam; PF00287; Na_K-ATPase; 1.
TIGRFAMs; TIGR01107; Na_K_ATPase_bet; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000001595};
Ion transport {ECO:0000256|RuleBase:RU362099};
Membrane {ECO:0000256|RuleBase:RU362099};
Reference proteome {ECO:0000313|Proteomes:UP000001595};
Transmembrane {ECO:0000256|RuleBase:RU362099};
Transmembrane helix {ECO:0000256|RuleBase:RU362099};
Transport {ECO:0000256|RuleBase:RU362099}.
TRANSMEM 20 48 Helical. {ECO:0000256|RuleBase:RU362099}.
SEQUENCE 265 AA; 29777 MW; C6C5E129E0A8365D CRC64;
MLSEGDILFS SLLSSRSLFW PPGLILLFYL VFYGFLAALF SFTMWVMLQT LNDEVPKYRD
QIPSPGLMVF PKPVTALEYT FSRSDPTSYA GYIEDLKKFL KPYTLEEQKN LTVCPDGALF
EQKGPVYVAC QFPVSLLQAC SGMNDPDFGY SQGNPCILVK MNRIIGLKPE GVPRIDCVSK
NEDIPNVAVY PHNGMIDLKY FPYYGKKLHV GYLQPLVAVQ VSFAPNNTGK EVTIECKIDG
SANLKSQDDR DKFLGRVMFK ITARA


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