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Spectinomycin tetracycline efflux pump

 A0A0M7MIL3_9BURK        Unreviewed;       485 AA.
A0A0M7MIL3;
09-DEC-2015, integrated into UniProtKB/TrEMBL.
09-DEC-2015, sequence version 1.
25-OCT-2017, entry version 9.
SubName: Full=Spectinomycin tetracycline efflux pump {ECO:0000313|EMBL:CUJ78092.1};
Name=stp_6 {ECO:0000313|EMBL:CUJ78092.1};
ORFNames=ERS370000_06163 {ECO:0000313|EMBL:CUJ78092.1};
Achromobacter sp.
Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
Alcaligenaceae; Achromobacter.
NCBI_TaxID=134375 {ECO:0000313|EMBL:CUJ78092.1, ECO:0000313|Proteomes:UP000044098};
[1] {ECO:0000313|EMBL:CUJ78092.1, ECO:0000313|Proteomes:UP000044098}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=2789STDY5608625 {ECO:0000313|EMBL:CUJ78092.1,
ECO:0000313|Proteomes:UP000044098};
Jackson K.R., Lunt B.L., Fisher J.N.B., Gardner A.V., Bailey M.E.,
Deus L.M., Earl A.S., Gibby P.D., Hartmann K.A., Liu J.E., Manci A.M.,
Nielsen D.A., Solomon M.B., Breakwell D.P., Burnett S.H., Grose J.H.;
Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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EMBL; CYTK01000019; CUJ78092.1; -; Genomic_DNA.
EnsemblBacteria; CUJ78092; CUJ78092; ERS370000_06163.
Proteomes; UP000044098; Unassembled WGS sequence.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005215; F:transporter activity; IEA:InterPro.
GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
CDD; cd06174; MFS; 1.
InterPro; IPR011701; MFS.
InterPro; IPR020846; MFS_dom.
InterPro; IPR036259; MFS_trans_sf.
InterPro; IPR005829; Sugar_transporter_CS.
Pfam; PF07690; MFS_1; 1.
SUPFAM; SSF103473; SSF103473; 3.
PROSITE; PS50850; MFS; 1.
PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000044098};
Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 21 {ECO:0000256|SAM:SignalP}.
CHAIN 22 485 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5005815495.
TRANSMEM 31 54 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 66 89 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 95 113 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 125 147 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 153 172 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 184 204 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 216 234 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 254 276 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 288 309 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 316 334 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 346 368 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 453 474 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 1 477 MFS. {ECO:0000259|PROSITE:PS50850}.
SEQUENCE 485 AA; 49794 MW; 729D27884EFF3078 CRC64;
MLAVCTAALI LPLSFSGGAI ATPAIGRDLG GHAQALGWIT NAFMLSFGSL LMAAGTLADA
YGRKRLFVAG VALFALVSVA LAFAPTVAWL DGLRALQGAG AAAALAGGSA SLAHACPGPA
RTRAFGLLGA SFGAGLALGP MLAGLLIDSL GWRSVFLSSA AVGAMALAVA LPRMQESRDP
QAGPLDWAGS LTFTGALALL TWGILEMPAA RGASALAWRL LAAAALCLLA FVAIERRVRR
PMLDLTLLRY PRFVGVQMLP VATCYCYVVL LVLLPIRFIG IEGRSEASAG LAMAALSAPL
LFMPAVAVWT MRWMSAGRSC ALGLLAAALG LYWLSRIGVE HAPQAALWPM LLIGAGTGLP
WGLMDGLSMS VAPPERAGMA AGIFSTTRVA GEGIALASVN ALLTFLIAHR LGADPGAAAQ
YLAAGDMAQA LVHQPGAAPA LLRQAYDDAF RQLLHALIAI TLACAAVVAL FLDAPRSQTL
QARMP


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