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Sperm associated antigen 9

 F6T9Q0_HORSE            Unreviewed;      1222 AA.
F6T9Q0;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
27-JUL-2011, sequence version 1.
05-DEC-2018, entry version 43.
SubName: Full=Sperm associated antigen 9 {ECO:0000313|Ensembl:ENSECAP00000013630};
Name=SPAG9 {ECO:0000313|VGNC:VGNC:23477};
Equus caballus (Horse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000013630, ECO:0000313|Proteomes:UP000002281};
[1] {ECO:0000313|Ensembl:ENSECAP00000013630, ECO:0000313|Proteomes:UP000002281}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000013630,
ECO:0000313|Proteomes:UP000002281};
PubMed=19892987; DOI=10.1126/science.1178158;
Broad Institute Genome Sequencing Platform;
Broad Institute Whole Genome Assembly Team;
Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H.,
Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N.,
Penedo M.C.T., Raison J.M., Sharpe T., Vogel J., Andersson L.,
Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J.,
Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J.,
Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R.,
Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F.,
Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L.,
Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M.,
White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
"Genome sequence, comparative analysis, and population genetics of the
domestic horse.";
Science 326:865-867(2009).
[2] {ECO:0000313|Ensembl:ENSECAP00000013630}
IDENTIFICATION.
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000013630};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
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STRING; 9796.ENSECAP00000013630; -.
PaxDb; F6T9Q0; -.
Ensembl; ENSECAT00000016848; ENSECAP00000013630; ENSECAG00000015256.
VGNC; VGNC:23477; SPAG9.
eggNOG; KOG2077; Eukaryota.
eggNOG; ENOG410XQ19; LUCA.
GeneTree; ENSGT00940000153496; -.
InParanoid; F6T9Q0; -.
OMA; HITPSVK; -.
OrthoDB; EOG091G016S; -.
TreeFam; TF313096; -.
Proteomes; UP000002281; Chromosome 11.
Bgee; ENSECAG00000015256; Expressed in 3 organ(s), highest expression level in prefrontal cortex.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0005815; C:microtubule organizing center; IEA:Ensembl.
GO; GO:0008432; F:JUN kinase binding; IBA:GO_Central.
GO; GO:0019894; F:kinesin binding; IBA:GO_Central.
GO; GO:0005078; F:MAP-kinase scaffold activity; IBA:GO_Central.
GO; GO:0030159; F:receptor signaling complex scaffold activity; IBA:GO_Central.
GO; GO:0007257; P:activation of JUN kinase activity; IBA:GO_Central.
GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Ensembl.
GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
Gene3D; 2.130.10.10; -; 1.
InterPro; IPR039911; JIP3/JIP4.
InterPro; IPR032486; JIP_LZII.
InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
InterPro; IPR034744; RH2.
InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
InterPro; IPR036322; WD40_repeat_dom_sf.
PANTHER; PTHR13886; PTHR13886; 1.
Pfam; PF16471; JIP_LZII; 1.
Pfam; PF09744; Jnk-SapK_ap_N; 1.
SUPFAM; SSF50978; SSF50978; 1.
PROSITE; PS51777; RH2; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000002281};
Reference proteome {ECO:0000313|Proteomes:UP000002281}.
DOMAIN 399 503 RH2. {ECO:0000259|PROSITE:PS51777}.
COILED 6 61 {ECO:0000256|SAM:Coils}.
COILED 330 392 {ECO:0000256|SAM:Coils}.
COILED 407 427 {ECO:0000256|SAM:Coils}.
COILED 626 653 {ECO:0000256|SAM:Coils}.
SEQUENCE 1222 AA; 134479 MW; F59763EA42F56E3D CRC64;
KFIEFEDSQE QEKKDLQTRV ESLESQTRQL ELKAKNYADQ ISRLEEREAE LKKEYNALHQ
RHTEMIHNYM EHLERTKLHQ LSGSDQLEST AHSRIRKERP ISLGIFPLPA GDGLLTPDTQ
KGGETPGSEQ WKFQELSQPR SHTSLKVNSS PESLKAVEQE DELSDVSQGG SKATTPASTA
ASDVAAIPAD TPLNEDGEGL VKAVDTPDKS EISKHIEVQV AQETRHVSTG SAENEEKSEV
QAIIESTPEL DMDKDLSGFK GSSTPTKGIE NKAFDRNTES LFEELSSAGS GLIGDVDEGA
DLLGMGREVE NLILENTQLL ETKNALNVVK NDLIAKVDEL TCEKDVLQGE LEAVKQAKLK
LEEKNRELEE ELRKARAEAE DARQKAKDDD DSDIPTAQRK RFTRVEMARV LMERNQYKER
LMELQEAVRW TEMIRASREN PAMQEKKRSS IWQFFSRLFS SSSNTAKKPE PPVNLKYNAP
TSHVTPSVKK RSSTLSQLPG DKSKAFDFLS EETEASLASR REQKREQYRQ VKAHVQKEDG
RVQAFGWSLP QKYKQVTNGQ GENKMKNLPV PVYLRPLDEK DTSMKLWCAV GVNLSGGKTR
DGGSVVGASV FYKDVAGLDA EGSKQRSASQ SSLDKLDQEL KEQQKELRNQ EELSSLVWIC
TSTHSATKVI IIDAVQPGNV LDSFTVCNSH VLCIASVPGA RETDYPAGEE LSESGQVDKA
SLCGSMTSTS SAETDSLLGG ITVVGCSTEG ATAAATSPST NGASPVMEKP PEKEAENSEV
DENVPTAEEA TEATEGNAGS AEDTVDISQT GVYTEHVFTD PLGVQIPEDL SPVYQSSNDS
DVYKDQIPVL PNEQDLVREE AQKMSSLLPT MWLGAQNGCL YVHSSVAQWR KCLHSIKLKD
SILSIVHVKG IVLVALADGT LAIFHRGVDG QWDLSNYHLL DLGRPHHSIR CMTVVHDKVW
CGYRNKIYVV QPKAMKIEAI KSFDAHPRKE SQVRQLAWVG DGVWVSIRLD STLRLYHAHT
YQHLQDVDIE PYVSKMLGTG KLGFSFVRIT ALMVSCNRLW VGTGNGVIIS IPLTETNKTS
GAPGNRPGSV IRVYGDENSD KVTPGTFIPY CSMAHAQLCF HGHRDAVKFF VAVPGQVVSP
QSGSSGTDLT GDKAGPSAQE PGSQTPLKSM LVISGGEGYI DFRMGDEGGE SELLGEDLPL
EPSVAKAERS HLIVWQVMYG SE


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