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Sperm associated antigen 9

 J9P381_CANLF            Unreviewed;      1328 AA.
J9P381;
31-OCT-2012, integrated into UniProtKB/TrEMBL.
31-OCT-2012, sequence version 1.
28-MAR-2018, entry version 28.
SubName: Full=Sperm associated antigen 9 {ECO:0000313|Ensembl:ENSCAFP00000040010};
Name=SPAG9 {ECO:0000313|Ensembl:ENSCAFP00000040010,
ECO:0000313|VGNC:VGNC:46699};
Canis lupus familiaris (Dog) (Canis familiaris).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
Canis.
NCBI_TaxID=9615 {ECO:0000313|Ensembl:ENSCAFP00000040010, ECO:0000313|Proteomes:UP000002254};
[1] {ECO:0000313|Ensembl:ENSCAFP00000040010, ECO:0000313|Proteomes:UP000002254}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000040010,
ECO:0000313|Proteomes:UP000002254};
PubMed=16341006; DOI=10.1038/nature04338;
Broad Sequencing Platform;
Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B.,
Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C.,
Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A.,
Ponting C.P., Galibert F., Smith D.R., deJong P.J., Kirkness E.F.,
Alvarez P., Biagi T., Brockman W., Butler J., Chin C.-W., Cook A.,
Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M.,
Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L.,
Koepfli K.-P., Parker H.G., Pollinger J.P., Searle S.M.J.,
Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A.,
Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P.,
Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L.,
Bachantsang P., Barry A., Bayul T., Benamara M., Berlin A.,
Bessette D., Blitshteyn B., Bloom T., Blye J., Boguslavskiy L.,
Bonnet C., Boukhgalter B., Brown A., Cahill P., Calixte N.,
Camarata J., Cheshatsang Y., Chu J., Citroen M., Collymore A.,
Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., Dhargay N.,
Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N.,
Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S.,
Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K.,
Foley C., Franke A., Friedrich D., Gage D., Garber M., Gearin G.,
Giannoukos G., Goode T., Goyette A., Graham J., Grandbois E.,
Gyaltsen K., Hafez N., Hagopian D., Hagos B., Hall J., Healy C.,
Hegarty R., Honan T., Horn A., Houde N., Hughes L., Hunnicutt L.,
Husby M., Jester B., Jones C., Kamat A., Kanga B., Kells C.,
Khazanovich D., Kieu A.C., Kisner P., Kumar M., Lance K., Landers T.,
Lara M., Lee W., Leger J.-P., Lennon N., Leuper L., LeVine S., Liu J.,
Liu X., Lokyitsang Y., Lokyitsang T., Lui A., Macdonald J., Major J.,
Marabella R., Maru K., Matthews C., McDonough S., Mehta T.,
Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., Miller K.,
Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., Naylor J.,
Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N.,
Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K.,
Osman S., Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F.,
Priest M., Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C.,
Rege F., Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S.,
Sharpe T., Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J.,
Smith C., Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S.,
Stone C., Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S.,
Thoulutsang D., Thoulutsang Y., Topham K., Topping I., Tsamla T.,
Vassiliev H., Venkataraman V., Vo A., Wangchuk T., Wangdi T.,
Weiand M., Wilkinson J., Wilson A., Yadav S., Yang S., Yang X.,
Young G., Yu Q., Zainoun J., Zembek L., Zimmer A., Lander E.S.;
"Genome sequence, comparative analysis and haplotype structure of the
domestic dog.";
Nature 438:803-819(2005).
[2] {ECO:0000313|Ensembl:ENSCAFP00000040010}
IDENTIFICATION.
STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000040010};
Ensembl;
Submitted (SEP-2012) to UniProtKB.
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EMBL; AAEX03006542; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AAEX03006543; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9615.ENSCAFP00000040010; -.
PaxDb; J9P381; -.
Ensembl; ENSCAFT00000044365; ENSCAFP00000040010; ENSCAFG00000017265.
VGNC; VGNC:46699; SPAG9.
eggNOG; KOG2077; Eukaryota.
eggNOG; ENOG410XQ19; LUCA.
GeneTree; ENSGT00670000097546; -.
InParanoid; J9P381; -.
OMA; RENPAMQ; -.
OrthoDB; EOG091G016S; -.
Reactome; R-CFA-375170; CDO in myogenesis.
Proteomes; UP000002254; Chromosome 9.
Bgee; ENSCAFG00000017265; -.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0005815; C:microtubule organizing center; IEA:Ensembl.
GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
GO; GO:0008432; F:JUN kinase binding; IBA:GO_Central.
GO; GO:0019894; F:kinesin binding; IBA:GO_Central.
GO; GO:0005078; F:MAP-kinase scaffold activity; IBA:GO_Central.
GO; GO:0048273; F:mitogen-activated protein kinase p38 binding; IEA:Ensembl.
GO; GO:0030159; F:receptor signaling complex scaffold activity; IBA:GO_Central.
GO; GO:0007257; P:activation of JUN kinase activity; IBA:GO_Central.
GO; GO:0090074; P:negative regulation of protein homodimerization activity; IEA:Ensembl.
GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Ensembl.
GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
Gene3D; 2.130.10.10; -; 1.
InterPro; IPR032486; JIP_LZII.
InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
InterPro; IPR034743; RH1.
InterPro; IPR034744; RH2.
InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
InterPro; IPR036322; WD40_repeat_dom_sf.
Pfam; PF16471; JIP_LZII; 1.
Pfam; PF09744; Jnk-SapK_ap_N; 1.
SUPFAM; SSF50978; SSF50978; 1.
PROSITE; PS51776; RH1; 1.
PROSITE; PS51777; RH2; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000002254};
Reference proteome {ECO:0000313|Proteomes:UP000002254}.
DOMAIN 7 95 RH1. {ECO:0000259|PROSITE:PS51776}.
DOMAIN 486 557 RH2. {ECO:0000259|PROSITE:PS51777}.
COILED 75 102 {ECO:0000256|SAM:Coils}.
COILED 107 162 {ECO:0000256|SAM:Coils}.
COILED 417 479 {ECO:0000256|SAM:Coils}.
COILED 494 514 {ECO:0000256|SAM:Coils}.
COILED 713 740 {ECO:0000256|SAM:Coils}.
SEQUENCE 1328 AA; 146751 MW; 76CE0AC20FBCC72C CRC64;
MELEDGVVYQ EEPGGSGAVM SERVSGLAGS IYREFERLIG RYDEEVVKEL MPLVVALLEN
LDSVFAQDQE HQVELELLRD DNEQLITQYE REKALRKHAE EKFIEFEDSQ EQEKKDLQTR
VESLESQTRQ LELKAKNYAD QISRLEEREA ELKKEYNALH QRHTEMIHNY MEHLERTKLH
QLSGSDQLES TAHSRIRKER PISLGIFPLP AGDGLLTPDT QKGGETPGSE QWKFQELSQP
RSHTSLKDEL SDVSQGGSKA TTPASTAASD VATIPTDTPL KEDNEGFVKV ADTPNKSEIS
KHIEVQVAQE TRNVSTGSAE NEEKSEVQAI IESTPELDMD KDLSGYKGSS TPTKGIENKA
FDRNTESLFE ELSSAGSGLI GDVDEGADLL GMGREVENLI LENTQLLETK HALNVVKNDL
IAKVDELTCE KDVLQGELEA VKQAKLKLEE KNKELEEELR KARAEAEDAR QKAKDDDDSD
IPTAQRKRFT RVEMARVLME RNQYKERLME LQEAVRWTEM IRASRENPAM QEKKRSSIWQ
FFSRLFSSSS NTTKKPEPPV NLKYNAPTSH VTPSVKKRSS TLSQLPGDKS KAFDFLSEET
EASLASRREQ KREQYRQVKA HVQKEDGRVQ AFGWSLPQKY KQVTNGQGEN KMKNLPVPVY
LRPLDEKDTS MKLWCAVGVN LSGGKTRDGG SVVGASVFYK DVAGLDTEGS KQRSASQSSL
DKLDQELKEQ QKELKNQEEL SSLVWICTST HSATKVIIID AIQPGNILDS FTVCNSHVLC
IASVPGARET DYPAGEELSE SGQVDKASLC GSMTSNSSAE TDSLLGGITV VGCSTEGVTA
AATSPSTNGA SPVTENPPEK EENSEVDENI PTAEEATEAT EGNAGSAEDT VDTSQPGVYT
EHVFTDPLGV QIPEDLSPVY QSSNDSDAYK DQLSVLPNEQ DLVREEAQKM SSLLPTMWLG
AQNGCLYVHS SVAQWRKCLH SIKLKDSILS IVHVKGIVLV ALADGTLAIF HRGVDGQWDL
SNYHLLDLGR PHHSIRCMTV VHDKVWCGYR NKIYVVQPKA MKIEKSFDAH PRKESQVRQL
AWVGDGVWVS IRLDSTLRLY HAHTYQHLQD VDIEPYVSKM LGTGKLGFSF VRITALMVSC
NRLWVGTGNG VIISIPLTET NKTSGAPGNR PGSVIRVYGD ENSDKVTPGT FIPYCSMAHA
QLCFHGHQDA VKFFVAVPGQ VISPQSGSSG TDLTGDKAGP STQEPGSQTP LKSMLVISGG
EGYIDFRMGD EGGESELLGE DLPLEPSVAK AERSHLIVWG LDLVFIQQSN NNLPPSNMTA
RTVAICSG


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