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Sperm associated antigen 9

 R4GBD4_ANOCA            Unreviewed;      1339 AA.
R4GBD4;
26-JUN-2013, integrated into UniProtKB/TrEMBL.
26-JUN-2013, sequence version 1.
12-SEP-2018, entry version 34.
SubName: Full=Sperm associated antigen 9 {ECO:0000313|Ensembl:ENSACAP00000022607};
Name=SPAG9 {ECO:0000313|Ensembl:ENSACAP00000022607};
Anolis carolinensis (Green anole) (American chameleon).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
Toxicofera; Iguania; Dactyloidae; Anolis.
NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000022607, ECO:0000313|Proteomes:UP000001646};
[1] {ECO:0000313|Ensembl:ENSACAP00000022607, ECO:0000313|Proteomes:UP000001646}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000022607};
The Genome Sequencing Platform;
Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
Lander E.S., Lindblad-Toh K.;
"The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSACAP00000022607}
IDENTIFICATION.
Ensembl;
Submitted (MAY-2013) to UniProtKB.
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Ensembl; ENSACAT00000030024; ENSACAP00000022607; ENSACAG00000001705.
eggNOG; KOG2077; Eukaryota.
eggNOG; ENOG410XQ19; LUCA.
GeneTree; ENSGT00670000097546; -.
OrthoDB; EOG091G016S; -.
Proteomes; UP000001646; Chromosome 2.
Bgee; ENSACAG00000001705; Expressed in 4 organ(s), highest expression level in brain.
ExpressionAtlas; R4GBD4; baseline.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0005815; C:microtubule organizing center; IEA:Ensembl.
GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
GO; GO:0008432; F:JUN kinase binding; IBA:GO_Central.
GO; GO:0019894; F:kinesin binding; IBA:GO_Central.
GO; GO:0005078; F:MAP-kinase scaffold activity; IBA:GO_Central.
GO; GO:0048273; F:mitogen-activated protein kinase p38 binding; IEA:Ensembl.
GO; GO:0030159; F:receptor signaling complex scaffold activity; IBA:GO_Central.
GO; GO:0007257; P:activation of JUN kinase activity; IBA:GO_Central.
GO; GO:0090074; P:negative regulation of protein homodimerization activity; IEA:Ensembl.
GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Ensembl.
GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
Gene3D; 2.130.10.10; -; 1.
InterPro; IPR032486; JIP_LZII.
InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
InterPro; IPR034743; RH1.
InterPro; IPR034744; RH2.
InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
InterPro; IPR036322; WD40_repeat_dom_sf.
Pfam; PF16471; JIP_LZII; 1.
Pfam; PF09744; Jnk-SapK_ap_N; 1.
SUPFAM; SSF50978; SSF50978; 1.
PROSITE; PS51776; RH1; 1.
PROSITE; PS51777; RH2; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000001646};
Reference proteome {ECO:0000313|Proteomes:UP000001646}.
DOMAIN 8 96 RH1. {ECO:0000259|PROSITE:PS51776}.
DOMAIN 503 607 RH2. {ECO:0000259|PROSITE:PS51777}.
COILED 76 163 {ECO:0000256|SAM:Coils}.
COILED 434 496 {ECO:0000256|SAM:Coils}.
COILED 511 531 {ECO:0000256|SAM:Coils}.
COILED 732 759 {ECO:0000256|SAM:Coils}.
SEQUENCE 1339 AA; 148002 MW; 380D06877937DD04 CRC64;
MELADGVVYQ EDPGGPGPAM MSERVSGLAG SIYREFERLI GRYDEEVVAE LMPLVVAVLE
NLDSVCAHSQ ETSVELELLR DDNEQLLTQY EREKALRKQA EEKFIEFEDS QEQEKKDLQI
RVETLESQTR QLELKAKNYA DQISRLEERE AELKKEYNAL HSRHTEMIHN YMEHLERAKL
HQLTGGDQVE PVMHTRVSPM PTVVRTLNRK EPPISLGIFP LPPGDAILTP DTQRGTVDTP
GSDTWKYREI SQPRSRTSLK DEISDVSQAG SKSTTPILTA ASDVLAPAES LQNEDKEGLV
KNSETENKNL DVSKNIEVQV AQETRSVSIG SNENEDKSEV QAIIESTPEL HIDKDLSGYK
GSSTPTKGIE NIAFDRNTES VFEELSSAGS GLIGDVDEGA DLLGEYSGMG REVENLILEN
TQLLETKHAL NVVKDDLIAK VDELNCEKDV LKGELEAVKL AKQKLEEKNK ELEEELRKAR
AEAEEARQKA KEDDDSDIPT AQRKRFTRVE MARVLMERNQ YKERLMELQE AVRWTEMIRA
SRENPAMQEK KRTSLWQFFS RLFSSSGTAA KKPEPPVNVK YNAPTSHITP SVKKRSSTLS
QLPSDKSKAF DFLSEESEAS LASRREQKRE QYRQVKAHVQ KEDGRVQAFG WSLPQKYKQA
VNGSGQSDNK MKNLPVPVYL RPLDEKDTSM KLWCAVGVNL SGGKTRDGGS VVGASVFYSD
VATVDAESNK QRSASQSSLD RLDQELKDQQ KELKNQEELS SLVWICTSTH SATKVIVVDA
NQPGNILDSF IVCNSHVLCI ASVPGALETD YPTGEEGSQE TDSGVVDKSS LCSSMNSSSS
AETDSLLGGI TVVGCTAEGI TGHSAPHSAN GASPEANKQP DVEAETDAVD ENVQTAEEAT
EATENAGSGE EVADVAQTGV YTEHVFTDPL GVQDTVEGSP AFQPSNETDL YKDVAVLPNE
QDLVREEAQK MSSLLPTMWL GAQNGCLYVH SSVAQWRKCV HAIKLKDSIL SIVHVKGIVL
VALADGTLAI FHRGVDGQWD LTNYHLLDLG RPHHSIRCMT VVHDKVWCGY RNKIYVVQPK
AMKIEKSFDA HPRKESQVRQ LAWVGDGVWV SIRLDSTLRL YHAHTYQHLQ DVDIEPYVSK
MLGTGKLGFS FVRITALMVS CNRLWVGTGN GVIISIPLTE TVILHQGRLL GLRANKAAAS
SGNRPGSVIR VYGDENSDKV TPGTFIPYCS MAHAQLCFHG HRDAVKFFVA VPGQVTCPQM
GGGPELINDK TTLSTQESNS QTSFKSMLVI SGGEGYIDFR MGDEAGESEL LGETLQLEPS
VAKAERSHLI VWQVMCGSE


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