Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Spliceosome-associated protein 130 B (AtSAP130b) (SAP 130 B) (Pre-mRNA-splicing factor SF3b 130 kDa subunit B) (SF3b130 B)

 S130B_ARATH             Reviewed;        1214 AA.
P0DKL6; Q570A5; Q9LD60;
12-APR-2017, integrated into UniProtKB/Swiss-Prot.
12-APR-2017, sequence version 1.
22-NOV-2017, entry version 8.
RecName: Full=Spliceosome-associated protein 130 B {ECO:0000303|PubMed:21680607};
Short=AtSAP130b {ECO:0000303|PubMed:21680607};
Short=SAP 130 B {ECO:0000303|PubMed:21680607};
AltName: Full=Pre-mRNA-splicing factor SF3b 130 kDa subunit B {ECO:0000303|PubMed:15987817};
Short=SF3b130 B {ECO:0000303|PubMed:15987817};
Name=SAP130B {ECO:0000303|PubMed:21680607};
Synonyms=SF3b130 {ECO:0000303|PubMed:15987817};
OrderedLocusNames=At3g55220 {ECO:0000312|Araport:AT3G55220};
ORFNames=T26I12.100 {ECO:0000312|EMBL:CAB75756.1};
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=11130713; DOI=10.1038/35048706;
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M.,
Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B.,
Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P.,
De Simone V., Choisne N., Artiguenave F., Robert C., Brottier P.,
Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F.,
Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V.,
Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S.,
Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G.,
Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B.,
Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G.,
Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J.,
Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D.,
Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
Monfort A., Argiriou A., Flores M., Liguori R., Vitale D.,
Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W.,
Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J.,
Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P.,
Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S.,
Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V.,
Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C.,
Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E.,
Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y.,
Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A.,
Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence and analysis of chromosome 3 of the plant Arabidopsis
thaliana.";
Nature 408:820-822(2000).
[2]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
The Arabidopsis Information Portal (Araport);
Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1050-1214.
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J.,
Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
[4]
GENE FAMILY.
PubMed=15987817; DOI=10.1261/rna.2440305;
Lorkovic Z.J., Lehner R., Forstner C., Barta A.;
"Evolutionary conservation of minor U12-type spliceosome between
plants and humans.";
RNA 11:1095-1107(2005).
[5]
FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, GENE FAMILY, AND
NOMENCLATURE.
STRAIN=cv. Columbia;
PubMed=21680607; DOI=10.1093/pcp/pcr077;
Aki S., Nakai H., Aoyama T., Oka A., Tsuge T.;
"AtSAP130/AtSF3b-3 function is required for reproduction in
Arabidopsis thaliana.";
Plant Cell Physiol. 52:1330-1339(2011).
-!- FUNCTION: Subunit of the splicing factor SF3B required for 'A'
complex assembly formed by the stable binding of U2 snRNP to the
branchpoint sequence (BPS) in pre-mRNA. Sequence independent
binding of SF3A/SF3B complex upstream of the branch site is
essential, it may anchor U2 snRNP to the pre-mRNA. May also be
involved in the assembly of the 'E' complex. Belongs also to the
minor U12-dependent spliceosome, which is involved in the splicing
of rare class of nuclear pre-mRNA intron (By similarity). Required
for pollen and ovule development, especially during the transition
from microspore to the bicellular stage in pollen development.
Involved in the accumulation of QRT1 and QRT3 (PubMed:21680607).
{ECO:0000250|UniProtKB:Q15393, ECO:0000269|PubMed:21680607}.
-!- SUBUNIT: Identified in the spliceosome C complex. Component of the
U11/U12 snRNPs that are part of the U12-type spliceosome.
Component of splicing factor SF3B complex.
{ECO:0000250|UniProtKB:Q15393}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q15393}.
-!- TISSUE SPECIFICITY: Expressed in roots, leaves, inflorescence and,
to a lower extent, in siliques. {ECO:0000269|PubMed:21680607}.
-!- DISRUPTION PHENOTYPE: The double mutant sap130a sap130b displays a
slight reduction in the size of aerial organs and in the number of
lateral roots, and is impaired in reproduction due to a reduced
production of viable pollen and impaired female reproductive
organs. Defect in the transition from microspore to the bicellular
stage in pollen development. Reduced expression of QRT1 and QRT3.
{ECO:0000269|PubMed:21680607}.
-!- SIMILARITY: Belongs to the RSE1 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AL132954; CAB75756.1; -; Genomic_DNA.
EMBL; CP002686; AEE79354.1; -; Genomic_DNA.
EMBL; AK220805; BAD94072.1; -; mRNA.
PIR; T47659; T47659.
RefSeq; NP_001319757.1; NM_001339727.1.
RefSeq; NP_001327611.1; NM_001339728.1.
RefSeq; NP_567015.1; NM_115378.4.
RefSeq; NP_567016.1; NM_115380.3.
UniGene; At.28226; -.
UniGene; At.72270; -.
SMR; P0DKL6; -.
EnsemblPlants; AT3G55200.1; AT3G55200.1; AT3G55200.
EnsemblPlants; AT3G55200.2; AT3G55200.2; AT3G55200.
EnsemblPlants; AT3G55200.3; AT3G55200.3; AT3G55200.
EnsemblPlants; AT3G55220.1; AT3G55220.1; AT3G55220.
GeneID; 824686; -.
GeneID; 824688; -.
Gramene; AT3G55200.1; AT3G55200.1; AT3G55200.
Gramene; AT3G55200.2; AT3G55200.2; AT3G55200.
Gramene; AT3G55200.3; AT3G55200.3; AT3G55200.
Gramene; AT3G55220.1; AT3G55220.1; AT3G55220.
KEGG; ath:AT3G55200; -.
KEGG; ath:AT3G55220; -.
Araport; AT3G55220; -.
eggNOG; KOG1898; Eukaryota.
eggNOG; ENOG410XPFQ; LUCA.
HOGENOM; HOG000216677; -.
KO; K12830; -.
Reactome; R-ATH-72163; mRNA Splicing - Major Pathway.
Reactome; R-ATH-72165; mRNA Splicing - Minor Pathway.
PRO; PR:P0DKL6; -.
Proteomes; UP000006548; Chromosome 3.
ExpressionAtlas; P0DKL6; baseline and differential.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO; GO:0055046; P:microgametogenesis; IMP:UniProtKB.
GO; GO:0048481; P:plant ovule development; IMP:UniProtKB.
GO; GO:0009555; P:pollen development; IMP:UniProtKB.
GO; GO:0009846; P:pollen germination; IMP:UniProtKB.
Gene3D; 2.130.10.10; -; 2.
InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
InterPro; IPR011044; Quino_amine_DH_bsu.
InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
InterPro; IPR036322; WD40_repeat_dom_sf.
Pfam; PF03178; CPSF_A; 1.
SUPFAM; SSF50969; SSF50969; 3.
SUPFAM; SSF50978; SSF50978; 2.
2: Evidence at transcript level;
Complete proteome; Nucleus; Reference proteome.
CHAIN 1 1214 Spliceosome-associated protein 130 B.
/FTId=PRO_0000439507.
CONFLICT 1154 1154 C -> R (in Ref. 3; BAD94072).
{ECO:0000305}.
SEQUENCE 1214 AA; 134967 MW; F21E86C930D11FC9 CRC64;
MYLYSLTLQQ ATGIVCAING NFSGGKTQEI AVARGKILDL LRPDENGKIQ TIHSVEVFGA
IRSLAQFRLT GAQKDYIVVG SDSGRIVILE YNKEKNVFDK VHQETFGKSG CRRIVPGQYV
AVDPKGRAVM IGACEKQKLV YVLNRDTTAR LTISSPLEAH KSHTICYSLC GVDCGFDNPI
FAAIELDYSE ADQDPTGQAA SEAQKHLTFY ELDLGLNHVS RKWSNPVDNG ANMLVTVPGG
ADGPSGVLVC AENFVIYMNQ GHPDVRAVIP RRTDLPAERG VLVVSAAVHK QKTMFFFLIQ
TEYGDVFKVT LDHNGDHVSE LKVKYFDTIP VASSICVLKL GFLFSASEFG NHGLYQFQAI
GEEPDVESSS SNLMETEEGF QPVFFQPRRL KNLVRIDQVE SLMPLMDMKV LNIFEEETPQ
IFSLCGRGPR SSLRILRPGL AITEMAVSQL PGQPSAVWTV KKNVSDEFDA YIVVSFTNAT
LVLSIGEQVE EVNDSGFLDT TPSLAVSLIG DDSLMQVHPN GIRHIREDGR INEWRTPGKR
SIVKVGYNRL QVVIALSGGE LIYFEADMTG QLMEVEKHEM SGDVACLDIA PVPEGRKRSR
FLAVGSYDNT VRILSLDPDD CLQILSVQSV SSAPESLLFL EVQASIGGDD GADHPANLFL
NSGLQNGVLF RTVVDMVTGQ LSDSRSRFLG LKPPKLFSIS VRGRSAMLCL SSRPWLGYIH
RGHFHLTPLS YETLEFAAPF SSDQCAEGVV SVAGDALRIF MIDRLGETFN ETVVPLRYTP
RKFVLHPKRK LLVIIESDQG AFTAEEREAA RKECFEAGGV GENGNGNADQ MENGADDEDK
EDPLSDEQYG YPKAESEKWV SCIRVLDPKT ATTTCLLELQ DNEAAYSVCT VNFHDKEYGT
LLAVGTVKGM QFWPKKNLVA GFIHIYRFVE DGKSLELLHK TQVEGVPLAL CQFQGRLLAG
IGPVLRLYDL GKKRLLRKCE NKLFPNTIIS IQTYRDRIYV GDIQESFHYC KYRRDENQLY
IFADDCVPRW LTASHHVDFD TMAGADKFGN VYFVRLPQDL SEEIEEDPTG GKIKWEQGKL
NGAPNKVDEI VQFHVGDVVT CLQKASMIPG GSESIMYGTV MGSIGALHAF TSRDDVDFFS
HLEMHMRQEY PPLCGRDHMA YRSAYFPVKD VIDGDLCEQF PTLPMDLQRK IADELDRTPA
EILKKLEDAR NKII


Related products :

Catalog number Product name Quantity
EIAAB38003 Kiaa0017,Mouse,Mus musculus,Pre-mRNA-splicing factor SF3b 130 kDa subunit,SAP 130,SF3b130,Sf3b3,Spliceosome-associated protein 130,Splicing factor 3B subunit 3
EIAAB38005 Bos taurus,Bovine,Pre-mRNA-splicing factor SF3b 130 kDa subunit,SAP 130,SF3b130,SF3B3,Spliceosome-associated protein 130,Splicing factor 3B subunit 3
EIAAB38004 Homo sapiens,Human,KIAA0017,Pre-mRNA-splicing factor SF3b 130 kDa subunit,SAP 130,SAP130,SF3b130,SF3B3,Spliceosome-associated protein 130,Splicing factor 3B subunit 3,STAF130
EIAAB38001 Mouse,Mus musculus,Pre-mRNA-splicing factor SF3b 155 kDa subunit,SAP 155,Sap155,Sf3b1,SF3b155,Spliceosome-associated protein 155,Splicing factor 3B subunit 1
EIAAB38006 Homo sapiens,Human,Pre-mRNA-splicing factor SF3b 49 kDa subunit,SAP 49,SAP49,SF3B4,SF3b50,Spliceosome-associated protein 49,Splicing factor 3B subunit 4
EIAAB38000 Homo sapiens,Human,Pre-mRNA-splicing factor SF3b 155 kDa subunit,SAP 155,SAP155,SF3B1,SF3b155,Spliceosome-associated protein 155,Splicing factor 3B subunit 1
EIAAB38002 Homo sapiens,Human,Pre-mRNA-splicing factor SF3b 145 kDa subunit,SAP 145,SAP145,SF3b145,SF3b150,SF3B2,Spliceosome-associated protein 145,Splicing factor 3B subunit 2
18-003-43613 Splicing factor 3B subunit 4 - Spliceosome-associated protein 49; SAP 49; SF3b50; Pre-mRNA-splicing factor SF3b 49 kDa subunit Polyclonal 0.1 mg Protein A
18-003-43556 Splicing factor 3B subunit 1 - Spliceosome-associated protein 155; SAP 155; SF3b155; Pre-mRNA-splicing factor SF3b 155 kDa subunit Polyclonal 0.1 mg Protein A
18-003-44198 Splicing factor 3B subunit 4 - Spliceosome-associated protein 49; SAP 49; SF3b50; Pre-mRNA-splicing factor SF3b 49 kDa subunit Polyclonal 0.05 mg Aff Pur
18-003-43555 Splicing factor 3B subunit 1 - Spliceosome-associated protein 155; SAP 155; SF3b155; Pre-mRNA-splicing factor SF3b 155 kDa subunit Polyclonal 0.1 mg Protein A
18-003-44215 Splicing factor 3B subunit 1 - Spliceosome-associated protein 155; SAP 155; SF3b155; Pre-mRNA-splicing factor SF3b 155 kDa subunit Polyclonal 0.1 mg Protein A
EIAAB38009 Homo sapiens,Human,Pre-mRNA-splicing factor SF3b 10 kDa subunit,SF3B10,SF3b5,SF3B5,Splicing factor 3B subunit 5
EIAAB38010 Mouse,Mus musculus,Pre-mRNA-splicing factor SF3b 10 kDa subunit,Sf3b10,SF3b5,Sf3b5,Splicing factor 3B subunit 5
EIAAB38011 Bos taurus,Bovine,Pre-mRNA-splicing factor SF3b 10 kDa subunit,SF3b5,SF3B5,Splicing factor 3B subunit 5
29-346 SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds 0.1 mg
29-345 SFPQ is DNA- and RNA binding protein. It is essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. It binds 0.1 mg
EIAAB39962 Alternative-splicing factor 1,ASF,ASF-1,Homo sapiens,Human,OK_SW-cl.3,pre-mRNA-splicing factor SF2, P33 subunit,Serine_arginine-rich splicing factor 1,SF2,SF2P33,SFRS1,Splicing factor, arginine_serine
18-003-44211 Splicing factor. arginine_serine-rich 1 - pre-mRNA-splicing factor SF2. P33 subunit; Alternative-splicing factor 1; ASF-1 Polyclonal 0.05 mg Aff Pur
18-003-44212 Splicing factor. arginine_serine-rich 1 - pre-mRNA-splicing factor SF2. P33 subunit; Alternative-splicing factor 1; ASF-1 Polyclonal 0.1 mg Protein A
EIAAB37998 Mouse,Mus musculus,SAP 61,Sap61,Sf3a3,SF3a60,Spliceosome-associated protein 61,Splicing factor 3A subunit 3
EIAAB37996 Mouse,Mus musculus,SAP 62,Sap62,Sf3a2,SF3a66,Spliceosome-associated protein 62,Splicing factor 3A subunit 2
EIAAB37995 Homo sapiens,Human,SAP 62,SAP62,SF3A2,SF3a66,Spliceosome-associated protein 62,Splicing factor 3A subunit 2
EIAAB37999 Homo sapiens,Human,SAP 61,SAP61,SF3A3,SF3a60,Spliceosome-associated protein 61,Splicing factor 3A subunit 3
EIAAB37991 Homo sapiens,Human,SAP 114,SAP114,SF3A1,SF3a120,Spliceosome-associated protein 114,Splicing factor 3A subunit 1


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur