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Stomach ghrelin (Fragment)

 B6SF63_MACEU            Unreviewed;        69 AA.
B6SF63;
16-DEC-2008, integrated into UniProtKB/TrEMBL.
16-DEC-2008, sequence version 1.
05-JUL-2017, entry version 36.
SubName: Full=Stomach ghrelin {ECO:0000313|EMBL:ACG50800.1};
Flags: Fragment;
Macropus eugenii (Tammar wallaby) (Notamacropus eugenii).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Metatheria; Diprotodontia; Macropodidae; Notamacropus.
NCBI_TaxID=9315 {ECO:0000313|EMBL:ACG50800.1};
[1] {ECO:0000313|EMBL:ACG50800.1}
NUCLEOTIDE SEQUENCE.
PubMed=19026714; DOI=10.1016/j.mce.2008.10.033;
Menzies B.R., Shaw G., Fletcher T.P., Renfree M.B.;
"Early onset of ghrelin production in a marsupial.";
Mol. Cell. Endocrinol. 299:266-273(2009).
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EMBL; EU883784; ACG50800.1; -; mRNA.
eggNOG; ENOG410IZYV; Eukaryota.
eggNOG; ENOG410ZG1B; LUCA.
HOGENOM; HOG000236303; -.
OrthoDB; EOG091G0YG0; -.
TreeFam; TF336219; -.
GO; GO:0030424; C:axon; IEA:Ensembl.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0005615; C:extracellular space; IEA:Ensembl.
GO; GO:0098794; C:postsynapse; IEA:GOC.
GO; GO:0016608; F:growth hormone-releasing hormone activity; IEA:InterPro.
GO; GO:0030296; F:protein tyrosine kinase activator activity; IEA:Ensembl.
GO; GO:0008154; P:actin polymerization or depolymerization; IEA:Ensembl.
GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
GO; GO:0046697; P:decidualization; IEA:Ensembl.
GO; GO:0016358; P:dendrite development; IEA:Ensembl.
GO; GO:0060079; P:excitatory postsynaptic potential; IEA:Ensembl.
GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
GO; GO:0042322; P:negative regulation of circadian sleep/wake cycle, REM sleep; IEA:Ensembl.
GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IEA:Ensembl.
GO; GO:2000506; P:negative regulation of energy homeostasis; IEA:Ensembl.
GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IEA:Ensembl.
GO; GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
GO; GO:0040013; P:negative regulation of locomotion; IEA:Ensembl.
GO; GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IEA:Ensembl.
GO; GO:0032100; P:positive regulation of appetite; IEA:Ensembl.
GO; GO:0046010; P:positive regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
GO; GO:0051461; P:positive regulation of corticotropin secretion; IEA:Ensembl.
GO; GO:0051464; P:positive regulation of cortisol secretion; IEA:Ensembl.
GO; GO:2000507; P:positive regulation of energy homeostasis; IEA:Ensembl.
GO; GO:0060124; P:positive regulation of growth hormone secretion; IEA:Ensembl.
GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
GO; GO:0009725; P:response to hormone; IEA:Ensembl.
InterPro; IPR006737; Motilin_assoc.
InterPro; IPR006738; Motilin_ghrelin.
InterPro; IPR005441; Preproghrelin.
PANTHER; PTHR14122; PTHR14122; 1.
Pfam; PF04643; Motilin_assoc; 1.
Pfam; PF04644; Motilin_ghrelin; 1.
2: Evidence at transcript level;
DOMAIN 1 26 Motilin_ghrelin.
{ECO:0000259|Pfam:PF04644}.
DOMAIN 33 69 Motilin_assoc.
{ECO:0000259|Pfam:PF04643}.
NON_TER 1 1 {ECO:0000313|EMBL:ACG50800.1}.
NON_TER 69 69 {ECO:0000313|EMBL:ACG50800.1}.
SEQUENCE 69 AA; 7742 MW; C9EDEF65CBD9375E CRC64;
GSSFLSPEHP KTQRKESKKP AKLQPRDVED TLSQPEGVEK GLEIQFNAPF DIGIKVAEAQ
YQQYGRALE


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