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Sugar efflux transporter A

 SOTA_DICCH              Reviewed;         393 AA.
Q9S3K0;
01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
01-MAY-2000, sequence version 1.
25-OCT-2017, entry version 70.
RecName: Full=Sugar efflux transporter A;
Name=sotA;
Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia
chrysanthemi).
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
Pectobacteriaceae; Dickeya.
NCBI_TaxID=556;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
STRAIN=A350;
PubMed=10671456; DOI=10.1128/JB.182.5.1340-1345.2000;
Condemine G.;
"Characterization of SotA and SotB, two Erwinia chrysanthemi proteins
which modify isopropyl-beta-D-thiogalactopyranoside and lactose
induction of the Escherichia coli lac promoter.";
J. Bacteriol. 182:1340-1345(2000).
-!- FUNCTION: Involved in the efflux of sugars. The physiological role
may be the reduction of the intracellular concentration of toxic
sugars or sugar metabolites. Transports IPTG, lactose and
arabinose.
-!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-
pass membrane protein {ECO:0000305}.
-!- INDUCTION: Activated by cyclic AMP receptor protein (CRP).
-!- SIMILARITY: Belongs to the major facilitator superfamily. Set
transporter family. {ECO:0000305}.
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EMBL; AJ249180; CAB53452.1; -; Genomic_DNA.
ProteinModelPortal; Q9S3K0; -.
TCDB; 2.A.1.20.4; the major facilitator superfamily (mfs).
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0015542; F:sugar efflux transmembrane transporter activity; IEA:InterPro.
CDD; cd06174; MFS; 1.
InterPro; IPR011701; MFS.
InterPro; IPR020846; MFS_dom.
InterPro; IPR036259; MFS_trans_sf.
InterPro; IPR004750; Sugar_efflux.
PANTHER; PTHR23535:SF2; PTHR23535:SF2; 1.
Pfam; PF07690; MFS_1; 1.
SUPFAM; SSF103473; SSF103473; 1.
TIGRFAMs; TIGR00899; 2A0120; 1.
PROSITE; PS50850; MFS; 1.
1: Evidence at protein level;
Cell inner membrane; Cell membrane; Membrane; Sugar transport;
Transmembrane; Transmembrane helix; Transport.
CHAIN 1 393 Sugar efflux transporter A.
/FTId=PRO_0000209363.
TRANSMEM 22 42 Helical. {ECO:0000255}.
TRANSMEM 51 71 Helical. {ECO:0000255}.
TRANSMEM 82 102 Helical. {ECO:0000255}.
TRANSMEM 107 127 Helical. {ECO:0000255}.
TRANSMEM 152 172 Helical. {ECO:0000255}.
TRANSMEM 174 194 Helical. {ECO:0000255}.
TRANSMEM 219 239 Helical. {ECO:0000255}.
TRANSMEM 253 273 Helical. {ECO:0000255}.
TRANSMEM 287 307 Helical. {ECO:0000255}.
TRANSMEM 308 328 Helical. {ECO:0000255}.
TRANSMEM 344 364 Helical. {ECO:0000255}.
TRANSMEM 366 386 Helical. {ECO:0000255}.
SEQUENCE 393 AA; 42428 MW; 1A47A92FE586F701 CRC64;
MTISSARTAR RLPDLTSSAF LVIAFLTGIA GALQLPTLSL FLSTEVQVRP FMVGLFYTGS
AVIGIVVSQI LATYSDRQGD RKTLILQCCL LGALACLLYA WNRNYFVLLF IGVLLSSFGS
TANPQLFALA REHADRTGRG AAMFSSVMRA QISLSWVIGP PVAFALALGF GFPAMYLTAA
VVFVLCGLLV WLLLPSMPKT RVKSAATLES PRQNRRDTLL LFTACTLMWT CNGIYLINMP
LYLVNELRLP EKLAGVMMGT AAGLEIPVML LAGYLTSRLG KRLLMRLAVI AGLIFYTGLT
LLNGSWALLA LQLLNAIFIG ILAGMGMLYF QDLMPGQAGA ATTLFTNTTR VGWIISGSLA
GIVAEVWSYH AGFVIAIAML AGAAVCMWRI RDV


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