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T-lymphocyte activation antigen CD86 (Fragment)

 D3Z363_MOUSE            Unreviewed;       135 AA.
D3Z363;
20-APR-2010, integrated into UniProtKB/TrEMBL.
20-APR-2010, sequence version 1.
12-SEP-2018, entry version 53.
SubName: Full=T-lymphocyte activation antigen CD86 {ECO:0000313|Ensembl:ENSMUSP00000117756};
Flags: Fragment;
Name=Cd86 {ECO:0000313|Ensembl:ENSMUSP00000117756,
ECO:0000313|MGI:MGI:101773};
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000117756, ECO:0000313|Proteomes:UP000000589};
[1] {ECO:0000313|Ensembl:ENSMUSP00000117756, ECO:0000313|Proteomes:UP000000589}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000117756,
ECO:0000313|Proteomes:UP000000589};
PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
Lindblad-Toh K., Eichler E.E., Ponting C.P.;
"Lineage-specific biology revealed by a finished genome assembly of
the mouse.";
PLoS Biol. 7:E1000112-E1000112(2009).
[2] {ECO:0000313|Ensembl:ENSMUSP00000117756}
IDENTIFICATION.
STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000117756};
Ensembl;
Submitted (MAY-2011) to UniProtKB.
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EMBL; AC117662; -; NOT_ANNOTATED_CDS; Genomic_DNA.
SMR; D3Z363; -.
MaxQB; D3Z363; -.
PeptideAtlas; D3Z363; -.
PRIDE; D3Z363; -.
Ensembl; ENSMUST00000135280; ENSMUSP00000117756; ENSMUSG00000022901.
MGI; MGI:101773; Cd86.
eggNOG; ENOG410IYP1; Eukaryota.
eggNOG; ENOG410ZD66; LUCA.
GeneTree; ENSGT00720000108819; -.
Proteomes; UP000000589; Chromosome 16.
Bgee; ENSMUSG00000022901; Expressed in 98 organ(s), highest expression level in spleen.
ExpressionAtlas; D3Z363; baseline and differential.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:Ensembl.
GO; GO:0042113; P:B cell activation; IEA:Ensembl.
GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
GO; GO:0034138; P:toll-like receptor 3 signaling pathway; IEA:Ensembl.
CDD; cd16087; IgV_CD86; 1.
Gene3D; 2.60.40.10; -; 1.
InterPro; IPR037677; CD86_IgV.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR013106; Ig_V-set.
Pfam; PF07686; V-set; 1.
SMART; SM00406; IGv; 1.
SUPFAM; SSF48726; SSF48726; 1.
PROSITE; PS50835; IG_LIKE; 1.
1: Evidence at protein level;
Complete proteome {ECO:0000313|Proteomes:UP000000589};
Proteomics identification {ECO:0000213|MaxQB:D3Z363,
ECO:0000213|PeptideAtlas:D3Z363};
Reference proteome {ECO:0000313|Proteomes:UP000000589}.
DOMAIN 43 133 Ig-like. {ECO:0000259|PROSITE:PS50835}.
NON_TER 135 135 {ECO:0000313|Ensembl:ENSMUSP00000117756}.
SEQUENCE 135 AA; 15337 MW; 0CE11F34DE5C6849 CRC64;
MYVIKTCATC TMGLAILIFV TVLLISDAVS VETQAYFNGT AYLPCPFTKA QNISLSELVV
FWQDQQKLVL YEHYLGTEKL DSVNAKYLGR TSFDRNNWTL RLHNVQIKDM GSYDCFIQKK
PPTGSIILQQ TLTEL


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