Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14)

 PARPT_MOUSE             Reviewed;         657 AA.
Q8C1B2; Q3UD50; Q8C032;
25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
01-MAR-2003, sequence version 1.
23-MAY-2018, entry version 110.
RecName: Full=TCDD-inducible poly [ADP-ribose] polymerase;
EC=2.4.2.30;
AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 14;
Short=ARTD14;
Name=Tiparp;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INDUCTION, AND TISSUE
SPECIFICITY.
PubMed=11716501; DOI=10.1006/bbrc.2001.5987;
Ma Q., Baldwin K.T., Renzelli A.J., McDaniel A., Dong L.;
"TCDD-inducible poly(ADP-ribose) polymerase: a novel response to
2,3,7,8-tetrachlorodibenzo-p-dioxin.";
Biochem. Biophys. Res. Commun. 289:499-506(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J; TISSUE=Bone marrow, Olfactory bulb, and Skin;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J; TISSUE=Eye;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[4]
INDUCTION.
PubMed=12147270; DOI=10.1016/S0003-9861(02)00339-9;
Ma Q.;
"Induction and superinduction of 2,3,7,8-tetrachlorodibenzo-rho-
dioxin-inducible poly(ADP-ribose) polymerase: role of the aryl
hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator
transcription activation domains and a labile transcription
repressor.";
Arch. Biochem. Biophys. 404:309-316(2002).
-!- FUNCTION: Poly [ADP-ribose] polymerase using NAD(+) as a substrate
to transfer ADP-ribose onto glutamic acid residues of a protein
acceptor; repeated rounds of ADP-ribosylation leads to the
formation of poly(ADPribose) chains on the protein, thereby
altering the function of the target protein. May play a role in
the adaptive response to chemical exposure (TCDD) and thereby
mediates certain effects of the chemicals.
{ECO:0000269|PubMed:11716501}.
-!- CATALYTIC ACTIVITY: NAD(+) + (ADP-D-ribosyl)(n)-acceptor =
nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
{ECO:0000255|PROSITE-ProRule:PRU00397}.
-!- TISSUE SPECIFICITY: Ubiquitously expressed.
{ECO:0000269|PubMed:11716501}.
-!- INDUCTION: By 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which is
a by-product of industrial processes and an important
environmental contaminant. This induction is concentration and
time-dependent and is mediated through an aryl hydrocarbon
receptor (AhR) and aryl hydrocarbon receptor nuclear translocation
(Arnt) signal transduction. Superinduced by cycloheximide and by
inhibitors of the 26S proteasome. {ECO:0000269|PubMed:11716501,
ECO:0000269|PubMed:12147270}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AK028529; BAC25994.1; -; mRNA.
EMBL; AK032453; BAC27876.1; -; mRNA.
EMBL; AK150248; BAE29412.1; -; mRNA.
EMBL; AK162094; BAE36720.1; -; mRNA.
EMBL; BC068173; AAH68173.1; -; mRNA.
CCDS; CCDS17388.1; -.
RefSeq; NP_849223.2; NM_178892.5.
UniGene; Mm.246398; -.
ProteinModelPortal; Q8C1B2; -.
SMR; Q8C1B2; -.
STRING; 10090.ENSMUSP00000048051; -.
iPTMnet; Q8C1B2; -.
PhosphoSitePlus; Q8C1B2; -.
PaxDb; Q8C1B2; -.
PRIDE; Q8C1B2; -.
Ensembl; ENSMUST00000047906; ENSMUSP00000048051; ENSMUSG00000034640.
GeneID; 99929; -.
KEGG; mmu:99929; -.
UCSC; uc008pkr.1; mouse.
CTD; 25976; -.
MGI; MGI:2159210; Tiparp.
eggNOG; ENOG410IIZH; Eukaryota.
eggNOG; ENOG410YI58; LUCA.
GeneTree; ENSGT00760000119084; -.
HOGENOM; HOG000115453; -.
HOVERGEN; HBG082109; -.
InParanoid; Q8C1B2; -.
KO; K15259; -.
OMA; DDFSCQM; -.
OrthoDB; EOG091G14UY; -.
PhylomeDB; Q8C1B2; -.
TreeFam; TF328965; -.
ChiTaRS; Tiparp; mouse.
PRO; PR:Q8C1B2; -.
Proteomes; UP000000589; Chromosome 3.
Bgee; ENSMUSG00000034640; -.
CleanEx; MM_TIPARP; -.
ExpressionAtlas; Q8C1B2; baseline and differential.
Genevisible; Q8C1B2; MM.
GO; GO:0005634; C:nucleus; ISO:MGI.
GO; GO:0035326; F:enhancer binding; ISO:MGI.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:MGI.
GO; GO:0008209; P:androgen metabolic process; IMP:MGI.
GO; GO:0071407; P:cellular response to organic cyclic compound; ISO:MGI.
GO; GO:0008210; P:estrogen metabolic process; IMP:MGI.
GO; GO:0060325; P:face morphogenesis; IMP:MGI.
GO; GO:0008585; P:female gonad development; IMP:MGI.
GO; GO:0030097; P:hemopoiesis; IMP:MGI.
GO; GO:0001822; P:kidney development; IMP:MGI.
GO; GO:0010629; P:negative regulation of gene expression; ISO:MGI.
GO; GO:0006807; P:nitrogen compound metabolic process; IMP:MGI.
GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.
GO; GO:0045732; P:positive regulation of protein catabolic process; ISO:MGI.
GO; GO:0009791; P:post-embryonic development; IMP:MGI.
GO; GO:0006471; P:protein ADP-ribosylation; IDA:MGI.
GO; GO:0060021; P:roof of mouth development; IMP:MGI.
GO; GO:0048705; P:skeletal system morphogenesis; IMP:MGI.
GO; GO:0048745; P:smooth muscle tissue development; IMP:MGI.
GO; GO:0001570; P:vasculogenesis; IMP:MGI.
InterPro; IPR012317; Poly(ADP-ribose)pol_cat_dom.
InterPro; IPR004170; WWE-dom.
InterPro; IPR037197; WWE_dom_sf.
InterPro; IPR000571; Znf_CCCH.
Pfam; PF00644; PARP; 1.
SUPFAM; SSF117839; SSF117839; 1.
PROSITE; PS51059; PARP_CATALYTIC; 1.
PROSITE; PS50918; WWE; 1.
PROSITE; PS50103; ZF_C3H1; 1.
2: Evidence at transcript level;
Complete proteome; Glycosyltransferase; Metal-binding; NAD;
Reference proteome; Transferase; Zinc; Zinc-finger.
CHAIN 1 657 TCDD-inducible poly [ADP-ribose]
polymerase.
/FTId=PRO_0000247836.
DOMAIN 333 411 WWE. {ECO:0000255|PROSITE-
ProRule:PRU00248}.
DOMAIN 449 657 PARP catalytic. {ECO:0000255|PROSITE-
ProRule:PRU00397}.
ZN_FING 238 265 C3H1-type. {ECO:0000255|PROSITE-
ProRule:PRU00723}.
CONFLICT 521 521 R -> H (in Ref. 2; BAC27876).
{ECO:0000305}.
CONFLICT 620 620 D -> N (in Ref. 2; BAC27876).
{ECO:0000305}.
SEQUENCE 657 AA; 75901 MW; 332CB9721C7EBC33 CRC64;
MEVETTEPEP DCVVQPPSPS DDFSCQMRIS EKISPLKTCF KKKQEQKRLG TGTLRSLRPI
LNTLLESGSL DGVFRARDQN RDESSLHEHI VKKPLEINPS CPPAENSMPV LIPDGTNVEG
QLPEAHPSTD APEQGVPIQD HSFPPETISG TVADSTTGHF QTDLLHPVSG DVPTSPDCVD
KVMDYVPGAF QDNSFTIQYI LDTSDKLSTE LFQDKSEEAS LELVFELVNQ LQYHTHQENG
IEICMDFLQG TCIYGRDCLK HHTVLPYHWQ IKRTTTQKWQ SVSNDSQEHL ERFYCNPEND
RMRMKYGGQD FWADLNAMTV FETTEFDQLR RLSTPPCSNS NSIYHTFWKF FCRDHFGWRE
YPESVVRLIE EANSRGLKEV RFMMWNNHYI LHNSFFRREI KRRPLFRSCF ILIPYLQTLG
GVPTQASLPL EATSSQIICP DGVTSANFYP ETWVYMHPSQ DFIQVPVSAE DKSYRIIYNL
FHKTVPEFKY RILQILRVQN QFLWEKYKRK KEYMNRKMSG RDRIINERHL FHGTSQDVVD
GICKHNFDPR VCGKHATMFG QGSYFAKKAS YSHNFSKKSS KGVHFMFLAK VLTGRYTMGS
HGMRRPPPVN PGSVTSDLYD SCVDNFFEPQ IFVIFNDDQS YPYFVIQYEE VSNTVSI


Related products :

Catalog number Product name Quantity
EIAAB29933 Homo sapiens,Human,PARP7,PARP-7,Poly [ADP-ribose] polymerase 7,TCDD-inducible poly [ADP-ribose] polymerase,TIPARP
E3448h Human TCDD Inducible Poly ADP Ribose Polymerase EL 96T
PARPT_HUMAN Human ELISA Kit FOR TCDD-inducible poly [ADP-ribose] polymerase 96T
CSB-EL023567HU Human TCDD-inducible poly [ADP-ribose] polymerase(TIPARP) ELISA kit 96T
H4890 TCDD-inducible poly [ADP-ribose] polymerase (TIPARP), Human, ELISA Kit 96T
H4891 TCDD-inducible poly [ADP-ribose] polymerase (TIPARP), Mouse, ELISA Kit 96T
CSB-EL023567MO Mouse TCDD-inducible poly [ADP-ribose] polymerase(TIPARP) ELISA kit 96T
EIAAB29934 Mouse,Mus musculus,TCDD-inducible poly [ADP-ribose] polymerase,Tiparp
CSB-EL023567MO Mouse TCDD-inducible poly [ADP-ribose] polymerase(TIPARP) ELISA kit SpeciesMouse 96T
CSB-EL023567HU Human TCDD-inducible poly [ADP-ribose] polymerase(TIPARP) ELISA kit SpeciesHuman 96T
PARPT_MOUSE ELISA Kit FOR TCDD-inducible poly [ADP-ribose] polymerase; organism: Mouse; gene name: Tiparp 96T
TIPARP TIPARP Gene TCDD-inducible poly(ADP-ribose) polymerase
CSB-EL023567HU Human TCDD-inducible poly(ADP-ribose) polymerase (TIPARP) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL023567MO Mouse TCDD-inducible poly(ADP-ribose) polymerase (TIPARP) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
18-003-42430 Poly [ADP-ribose] polymerase 2 - EC 2.4.2.30; PARP-2; NAD(+) ADP-ribosyltransferase 2; Poly[ADP-ribose] synthetase 2; pADPRT-2; hPARP-2 Polyclonal 0.05 mg Aff Pur
18-003-42429 Poly [ADP-ribose] polymerase 1 - EC 2.4.2.30; PARP-1; ADPRT; NAD(+) ADP-ribosyltransferase 1; Poly[ADP-ribose] synthetase 1 Polyclonal 0.1 mg Protein A
EIAAB29924 ADPRT2,ADPRT-2,ADPRTL2,Homo sapiens,hPARP-2,Human,NAD(+) ADP-ribosyltransferase 2,pADPRT-2,PARP2,PARP-2,Poly [ADP-ribose] polymerase 2,Poly[ADP-ribose] synthase 2
EIAAB29923 Adprt2,ADPRT-2,Adprtl2,Aspartl2,Mouse,mPARP-2,Mus musculus,NAD(+) ADP-ribosyltransferase 2,pADPRT-2,Parp2,PARP-2,Poly [ADP-ribose] polymerase 2,Poly[ADP-ribose] synthase 2
EIAAB29925 ADPRT3,ADPRT-3,ADPRTL3,Homo sapiens,hPARP-3,Human,IRT1,NAD(+) ADP-ribosyltransferase 3,pADPRT-3,PARP3,PARP-3,Poly [ADP-ribose] polymerase 3,Poly[ADP-ribose] synthase 3
E0947h ELISA kit ADPRT,ADPRT 1,Homo sapiens,Human,NAD(+) ADP-ribosyltransferase 1,PARP1,PARP-1,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1,PPOL 96T
E0947h ELISA ADPRT,ADPRT 1,Homo sapiens,Human,NAD(+) ADP-ribosyltransferase 1,PARP1,PARP-1,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1,PPOL 96T
U0947h CLIA ADPRT,ADPRT 1,Homo sapiens,Human,NAD(+) ADP-ribosyltransferase 1,PARP1,PARP-1,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1,PPOL 96T
U0947m CLIA Adprp,Adprt,ADPRT 1,Adprt1,Mouse,msPARP,Mus musculus,NAD(+) ADP-ribosyltransferase 1,Parp1,PARP-1,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1 96T
E0947m ELISA kit Adprp,Adprt,ADPRT 1,Adprt1,Mouse,msPARP,Mus musculus,NAD(+) ADP-ribosyltransferase 1,Parp1,PARP-1,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1 96T
E0947m ELISA Adprp,Adprt,ADPRT 1,Adprt1,Mouse,msPARP,Mus musculus,NAD(+) ADP-ribosyltransferase 1,Parp1,PARP-1,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur