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Teicoplanin resistance associated membrane protein TcaB

 A0A073A969_9GAMM        Unreviewed;       402 AA.
A0A073A969;
01-OCT-2014, integrated into UniProtKB/TrEMBL.
01-OCT-2014, sequence version 1.
25-OCT-2017, entry version 11.
SubName: Full=Teicoplanin resistance associated membrane protein TcaB {ECO:0000313|EMBL:KEI35751.1};
Name=tcaB {ECO:0000313|EMBL:KEI35751.1};
ORFNames=FRA_29c03750 {ECO:0000313|EMBL:KEI35751.1};
Francisella sp. W12-1067.
Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
Francisellaceae; Francisella.
NCBI_TaxID=1385420 {ECO:0000313|EMBL:KEI35751.1, ECO:0000313|Proteomes:UP000027447};
[1] {ECO:0000313|EMBL:KEI35751.1, ECO:0000313|Proteomes:UP000027447}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=W12-1067 {ECO:0000313|EMBL:KEI35751.1,
ECO:0000313|Proteomes:UP000027447};
PubMed=24961323;
Rydzewski K., Schulz T., Brzuszkiewicz E., Holland G., Luck C.,
Fleischer J., Grunow R., Heuner K.;
"Genome sequence and phenotypic analysis of a first German Francisella
sp. isolate (W12-1067) not belonging to the species Francisella
tularensis.";
BMC Microbiol. 14:169-169(2014).
-!- CAUTION: The sequence shown here is derived from an
EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
preliminary data. {ECO:0000313|EMBL:KEI35751.1}.
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EMBL; AWHF01000026; KEI35751.1; -; Genomic_DNA.
RefSeq; WP_035719305.1; NZ_AWHF01000026.1.
EnsemblBacteria; KEI35751; KEI35751; FRA_29c03750.
PATRIC; fig|1385420.3.peg.373; -.
Proteomes; UP000027447; Unassembled WGS sequence.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005215; F:transporter activity; IEA:InterPro.
GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
CDD; cd06174; MFS; 1.
InterPro; IPR004812; Efflux_drug-R_Bcr/CmlA.
InterPro; IPR011701; MFS.
InterPro; IPR020846; MFS_dom.
InterPro; IPR036259; MFS_trans_sf.
Pfam; PF07690; MFS_1; 1.
SUPFAM; SSF103473; SSF103473; 1.
TIGRFAMs; TIGR00710; efflux_Bcr_CflA; 1.
PROSITE; PS50850; MFS; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000027447};
Membrane {ECO:0000256|SAM:Phobius};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 48 65 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 77 100 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 106 123 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 135 154 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 166 185 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 214 240 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 246 268 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 280 301 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 307 328 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 348 365 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 371 392 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 11 399 MFS. {ECO:0000259|PROSITE:PS50850}.
SEQUENCE 402 AA; 44287 MW; 2CB1BF173D6AFC4C CRC64;
MKYITRESKI FPIILALFAA LPPLAVNTYA PAISLIAQDF GVPDSQVLTT FATYFVGFSF
GMLFWGAISD KYGRKKIIII GSVIYILSTL LCSHSTSFTM LETLRFIQGL SDSVGGVIAF
SIARDCYKGT KLTNMVASIV IIMLIAPIVA PIIGTVFTNL TGTWQSTFYF LTFYGVIILI
AALLIEETLE PKNRQISILK IAPSYFQHLT NPGFMLATIA GGSTFAALLI YISSSAIIYL
EQYSTGSILY CIYYGICAIA SILANLLIKK HSHKIKDIKY TYYSIAVLAV SCTALAIFNY
LNIDNAFIYT IVMFILCATV AFICTILYSF SINQVDHNFG TANSISNFIK NMIAASGSFI
VSYYHGRDLI LASPIVQLGF IGITILILFI IYKMNIDSKI ND


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