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Tetraspanin

 M3W8H4_FELCA            Unreviewed;       215 AA.
M3W8H4;
01-MAY-2013, integrated into UniProtKB/TrEMBL.
01-MAY-2013, sequence version 1.
30-AUG-2017, entry version 33.
RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
Name=CD53 {ECO:0000313|Ensembl:ENSFCAP00000007263};
Felis catus (Cat) (Felis silvestris catus).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
Felinae; Felis.
NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000007263, ECO:0000313|Proteomes:UP000011712};
[1] {ECO:0000313|Ensembl:ENSFCAP00000007263, ECO:0000313|Proteomes:UP000011712}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000007263,
ECO:0000313|Proteomes:UP000011712};
PubMed=17975172; DOI=10.1101/gr.6380007;
Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
"Initial sequence and comparative analysis of the cat genome.";
Genome Res. 17:1675-1689(2007).
[2] {ECO:0000313|Ensembl:ENSFCAP00000007263}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000007263};
Hillier L.W., Warren W., Obrien S., Wilson R.K.;
"Sequence assembly of the Felis catus genome version 6.2.";
Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|Ensembl:ENSFCAP00000007263}
IDENTIFICATION.
STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000007263};
Ensembl;
Submitted (MAR-2013) to UniProtKB.
-!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU361218};
Multi-pass membrane protein {ECO:0000256|RuleBase:RU361218}.
-!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
{ECO:0000256|RuleBase:RU361218, ECO:0000256|SAAS:SAAS00545671}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSFCAP00000007263}.
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EMBL; AANG02141608; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_003990480.1; XM_003990431.3.
STRING; 9685.ENSFCAP00000007263; -.
Ensembl; ENSFCAT00000007846; ENSFCAP00000007263; ENSFCAG00000007844.
GeneID; 101084381; -.
KEGG; fca:101084381; -.
CTD; 963; -.
eggNOG; KOG3882; Eukaryota.
eggNOG; ENOG4111IRY; LUCA.
GeneTree; ENSGT00880000137858; -.
InParanoid; M3W8H4; -.
KO; K06489; -.
OMA; VCVIQVL; -.
OrthoDB; EOG091G0CQO; -.
Proteomes; UP000011712; Chromosome C1.
Bgee; ENSFCAG00000007844; -.
GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0001772; C:immunological synapse; IEA:Ensembl.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
GO; GO:1901741; P:positive regulation of myoblast fusion; IEA:Ensembl.
Gene3D; 1.10.1450.10; -; 1.
InterPro; IPR000301; Tetraspanin.
InterPro; IPR018499; Tetraspanin/Peripherin.
InterPro; IPR018503; Tetraspanin_CS.
InterPro; IPR008952; Tetraspanin_EC2.
Pfam; PF00335; Tetraspannin; 1.
PIRSF; PIRSF002419; Tetraspanin; 1.
PRINTS; PR00259; TMFOUR.
SUPFAM; SSF48652; SSF48652; 1.
PROSITE; PS00421; TM4_1; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000011712};
Membrane {ECO:0000256|RuleBase:RU361218,
ECO:0000256|SAAS:SAAS00028005};
Reference proteome {ECO:0000313|Proteomes:UP000011712};
Transmembrane {ECO:0000256|RuleBase:RU361218,
ECO:0000256|SAAS:SAAS00028005};
Transmembrane helix {ECO:0000256|RuleBase:RU361218,
ECO:0000256|SAAS:SAAS00028005}.
TRANSMEM 12 36 Helical. {ECO:0000256|RuleBase:RU361218}.
TRANSMEM 42 65 Helical. {ECO:0000256|RuleBase:RU361218}.
TRANSMEM 77 102 Helical. {ECO:0000256|RuleBase:RU361218}.
TRANSMEM 178 202 Helical. {ECO:0000256|RuleBase:RU361218}.
SEQUENCE 215 AA; 23944 MW; C008B4339074F532 CRC64;
MGMSGLKLLK YVLFFFNLLF WFCGCCILGF GIYFLIHNNL WLLPFLPLGN VLVIVGSIIM
VVAFLGCMGS IKENKCLLMS FFILLLIILL AEVTLAILLF VYEQKLNKYV SESLTTSIQK
YSSDNSTREM WDSIQSLLQC CGVNGTSDWN GHPPASCPQG PQVQGCYAKA KQWFHSNFLH
VGIITICVCV IQVLGMSFAL TLNCQIDKTS QALGL


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