Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Transcription factor 23 (TCF-23) (Basic helix-loop-helix transcription factor OUT) (Ovary, uterus and testis protein)

 TCF23_MOUSE             Reviewed;         209 AA.
Q9JLR5;
15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
25-OCT-2017, entry version 109.
RecName: Full=Transcription factor 23;
Short=TCF-23;
AltName: Full=Basic helix-loop-helix transcription factor OUT;
AltName: Full=Ovary, uterus and testis protein;
Name=Tcf23; Synonyms=Out;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, SUBUNIT,
SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
STRAIN=ICR; TISSUE=Ovary;
PubMed=10652346; DOI=10.1074/jbc.275.5.3510;
Narumi O., Mori S., Boku S., Tsuji Y., Hashimoto N., Nishikawa S.,
Yokota Y.;
"OUT, a novel basic helix-loop-helix transcription factor with an Id-
like inhibitory activity.";
J. Biol. Chem. 275:3510-3521(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J; TISSUE=Ovary, and Uterus;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Brain;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
-!- FUNCTION: Inhibits E-box-mediated binding and transactivation of
bHLH factors. Inhibitory effect is similar to that of ID proteins.
Inhibits the formation of TCF3 and MYOD1 homodimers and
heterodimers. Lacks DNA binding activity. May be involved in the
regulation or modulation of smooth muscle contraction of the
uterus during pregnancy and particularly around the time of
delivery. Seems to play a role in the inhibition of myogenesis.
{ECO:0000269|PubMed:10652346}.
-!- SUBUNIT: Forms inactive heterodimeric complex with TCF3.
{ECO:0000269|PubMed:10652346}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-
ProRule:PRU00981, ECO:0000269|PubMed:10652346}.
-!- TISSUE SPECIFICITY: Highly expressed in the uterus (predominantly
in myometrium), ovary, and testis. Expression in the uterus is
higher in the diestrus phase than in the estrus phase and reaches
a maximum at 7.5 dpc. Expression declines towards the time of
delivery and returns to the non-pregnant level 4 days after
delivery. Low expression seen in lung, heart, intestine, and
spleen. {ECO:0000269|PubMed:10652346}.
-!- DOMAIN: Both the bHLH region and the C-terminal portion are
essential for inhibitory function.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AB059397; BAB69473.1; -; Genomic_DNA.
EMBL; AF142405; AAF31168.1; -; mRNA.
EMBL; AK030277; BAC26873.1; -; mRNA.
EMBL; AK030297; BAC26885.1; -; mRNA.
EMBL; BC119346; AAI19347.1; -; mRNA.
EMBL; BC120609; AAI20610.1; -; mRNA.
CCDS; CCDS19168.1; -.
RefSeq; NP_444315.1; NM_053085.2.
UniGene; Mm.57874; -.
ProteinModelPortal; Q9JLR5; -.
STRING; 10090.ENSMUSP00000006818; -.
iPTMnet; Q9JLR5; -.
PhosphoSitePlus; Q9JLR5; -.
PaxDb; Q9JLR5; -.
PRIDE; Q9JLR5; -.
Ensembl; ENSMUST00000006818; ENSMUSP00000006818; ENSMUSG00000006642.
GeneID; 69852; -.
KEGG; mmu:69852; -.
UCSC; uc008wws.1; mouse.
CTD; 150921; -.
MGI; MGI:1934960; Tcf23.
eggNOG; KOG4029; Eukaryota.
eggNOG; ENOG411227D; LUCA.
GeneTree; ENSGT00710000106684; -.
HOGENOM; HOG000154520; -.
HOVERGEN; HBG096612; -.
InParanoid; Q9JLR5; -.
OMA; RTRQDLW; -.
OrthoDB; EOG091G0MGD; -.
PhylomeDB; Q9JLR5; -.
TreeFam; TF350742; -.
PRO; PR:Q9JLR5; -.
Proteomes; UP000000589; Chromosome 5.
Bgee; ENSMUSG00000006642; -.
CleanEx; MM_TCF23; -.
Genevisible; Q9JLR5; MM.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
CDD; cd00083; HLH; 1.
Gene3D; 4.10.280.10; -; 1.
InterPro; IPR011598; bHLH_dom.
InterPro; IPR036638; HLH_DNA-bd_sf.
Pfam; PF00010; HLH; 1.
SMART; SM00353; HLH; 1.
SUPFAM; SSF47459; SSF47459; 1.
PROSITE; PS50888; BHLH; 1.
1: Evidence at protein level;
Complete proteome; Developmental protein; Differentiation; Myogenesis;
Nucleus; Reference proteome.
CHAIN 1 209 Transcription factor 23.
/FTId=PRO_0000315821.
DOMAIN 75 127 bHLH. {ECO:0000255|PROSITE-
ProRule:PRU00981}.
SEQUENCE 209 AA; 22895 MW; 611E3878DE92446A CRC64;
MSQEATEAPA MPGEGHGHNK AKARWLLGTD RKRSRINRTR QDLWEDTSWS NHRLSRATSA
PRGTRARGTA HGRSEASPEN AARERTRVKT LRQAFLALQA ALPAVPPDTK LSKLDVLVLA
TSYIAHLTRT LGHELPGPAW PPFVRGLRYL HPLKKWPMRS RLYAGGLGCS DLDSTTAITT
GQRCKDAELG SQDSVAAESL LTSPAFGNK


Related products :

Catalog number Product name Quantity
EIAAB41702 Basic helix-loop-helix transcription factor OUT,Mouse,Mus musculus,Out,Ovary, uterus and testis protein,Tcf23,TCF-23,Transcription factor 23
18-003-44006 Basic helix-loop-helix transcription factor OUT - Transcription factor 23; 11 days pregnant adult female ovary and uterus cDNA. RIKEN full-length enriched library. clone 5031411E05 product transcripti 0.1 mg Protein A
EIAAB37697 Basic helix-loop-helix transcription factor scleraxis,bHLHa41,BHLHA41,bHLHa48,Class A basic helix-loop-helix protein 41,Class A basic helix-loop-helix protein 48,Homo sapiens,Human,SCX,SCXA
EIAAB32965 bHLH transcription factor p48,bHLHa29,BHLHA29,Class A basic helix-loop-helix protein 29,Homo sapiens,Human,p48 DNA-binding subunit of transcription factor PTF1,Pancreas transcription factor 1 subunit
EIAAB42114 bHLHe34,BHLHE34,Class E basic helix-loop-helix protein 34,Homo sapiens,hTFEC-L,Human,TCFEC,TFEC,TFE-C,TFECL,Transcription factor EC,Transcription factor EC-like
28-090 USF1 encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich i 0.1 mg
EIAAB28828 bHLHb7,BHLHB7,bHLHe20,BHLHE20,Class B basic helix-loop-helix protein 7,Class E basic helix-loop-helix protein 20,Homo sapiens,Human,OLIG3,Oligo3,Oligodendrocyte transcription factor 3
EIAAB28821 bHLHb6,BHLHB6,bHLHe21,BHLHE21,Class B basic helix-loop-helix protein 6,Class E basic helix-loop-helix protein 21,Homo sapiens,Human,OLIG1,Oligo1,Oligodendrocyte transcription factor 1
EIAAB28826 bHLHb1,BHLHB1,bHLHe19,BHLHE19,Class B basic helix-loop-helix protein 1,Class E basic helix-loop-helix protein 19,Homo sapiens,Human,OLIG2,Oligo2,Oligodendrocyte transcription factor 2,PRKCBP2,Protein
25-061 ATOH1 belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47.This protein belongs to the basic helix-loop-helix (BHLH) 0.05 mg
EIAAB45451 bHLHb12,BHLHB12,Class B basic helix-loop-helix protein 12,FIP,FOS-interacting protein,Homo sapiens,Human,Major late transcription factor 2,Upstream stimulatory factor 2,Upstream transcription factor 2
28-587 Mouse ASCL2 is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It is the first transcription factor shown to play a critical part in the development of the mammalian tro 0.1 mg
27-413 PTF1A is a pancreas specific transcription factor. Mammalian studies have implicated important roles for the basic helix-loop-helix transcription factor PTF1A-p48 in the development of both exocrine a 0.1 mg
EIAAB28827 bHLHb7,Bhlhb7,Class B basic helix-loop-helix protein 7,Mouse,Mus musculus,Olig3,Oligo3,Oligodendrocyte transcription factor 3,Oligodendrocyte-specific bHLH transcription factor 3
E1384088 Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) ELISA Kit
HIF3A HIF1A Gene hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
E1381863 Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) ELISA Kit 1
201-20-2528 HIF1A{hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)}rabbit.pAb 0.2ml
CSB-EL010351HO Horse hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A) ELISA kit 96T
CSB-EL010351HO Horse hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A) ELISA kit, Species , Sample Type 96T
E6875h Human Basic Helix Loop Helix Transcription Factor 96T
EIAAB37695 Basic helix-loop-helix transcription factor scleraxis,Mouse,Mus musculus,Scx
CSB-EL020869HU Human Basic helix-loop-helix transcription factor scleraxis(SCXA) ELISA kit 96T
EIAAB45447 bHLHb11,BHLHB11,Class B basic helix-loop-helix protein 11,Homo sapiens,Human,Major late transcription factor 1,Upstream stimulatory factor 1,USF,USF1
31-157 TAL1 is a basic helix-loop-helix transcription factor with a critical role in the development of both blood and endothelium. 0.05 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur