Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Triacylglycerol lipase SDP1 (EC 3.1.1.3) (Protein SUGAR-DEPENDENT 1)

 SDP1_ARATH              Reviewed;         825 AA.
Q9LZA6; Q56WV8;
05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
05-DEC-2018, entry version 105.
RecName: Full=Triacylglycerol lipase SDP1;
EC=3.1.1.3;
AltName: Full=Protein SUGAR-DEPENDENT 1;
Name=SDP1; OrderedLocusNames=At5g04040; ORFNames=F8F6.10, F8F6.250;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=11130714; DOI=10.1038/35048507;
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K.,
Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S.,
Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T.,
Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M.,
Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R.,
Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J.,
Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M.,
Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M.,
Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P.,
Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C.,
Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N.,
Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J.,
Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S.,
Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W.,
Ramsperger U., Wedler H., Balke K., Wedler E., Peters S.,
van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R.,
Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S.,
Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W.,
Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H.,
Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.;
"Sequence and analysis of chromosome 5 of the plant Arabidopsis
thaliana.";
Nature 408:823-826(2000).
[2]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
PubMed=27862469; DOI=10.1111/tpj.13415;
Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
Town C.D.;
"Araport11: a complete reannotation of the Arabidopsis thaliana
reference genome.";
Plant J. 89:789-804(2017).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
PubMed=14593172; DOI=10.1126/science.1088305;
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis
genome.";
Science 302:842-846(2003).
[4]
NUCLEOTIDE SEQUENCE [MRNA] OF 451-825.
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J.,
Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
[5]
FUNCTION, CATALYTIC ACTIVITY, DISRUPTION PHENOTYPE, MUTAGENESIS OF
GLY-241; GLU-438 AND PRO-456, ACTIVITY REGULATION, DEVELOPMENTAL
STAGE, AND SUBCELLULAR LOCATION.
PubMed=16473965; DOI=10.1105/tpc.105.040543;
Eastmond P.J.;
"SUGAR-DEPENDENT1 encodes a patatin domain triacylglycerol lipase that
initiates storage oil breakdown in germinating Arabidopsis seeds.";
Plant Cell 18:665-675(2006).
[6]
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=19376835; DOI=10.1104/pp.109.138677;
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
Grossmann J., Gruissem W., Baginsky S.;
"Large-scale Arabidopsis phosphoproteome profiling reveals novel
chloroplast kinase substrates and phosphorylation networks.";
Plant Physiol. 150:889-903(2009).
[7]
FUNCTION.
PubMed=19136267; DOI=10.1016/j.plaphy.2008.12.005;
Quettier A.L., Eastmond P.J.;
"Storage oil hydrolysis during early seedling growth.";
Plant Physiol. Biochem. 47:485-490(2009).
-!- FUNCTION: Involved in the release of fatty acids from the oil body
in germinating seedlings. Could hydrolyze triacylglycerols and
diacylglycerols but not monoacylglycerols, phospholipids,
galactolipids or cholesterol esters. {ECO:0000269|PubMed:16473965,
ECO:0000269|PubMed:19136267}.
-!- CATALYTIC ACTIVITY:
Reaction=a triacylglycerol + H2O = a diacylglycerol + a fatty acid
+ H(+); Xref=Rhea:RHEA:12044, ChEBI:CHEBI:15377,
ChEBI:CHEBI:15378, ChEBI:CHEBI:17855, ChEBI:CHEBI:18035,
ChEBI:CHEBI:28868; EC=3.1.1.3;
Evidence={ECO:0000269|PubMed:16473965};
-!- ACTIVITY REGULATION: Inhibited by diethyl-p-nitrophenyl phosphate,
diisopropyl fluorophosphate and [E]-6-[bromoethylene]-3-[1-
naphthalenyl]-2H-tetrahydropyran-2-one.
{ECO:0000269|PubMed:16473965}.
-!- BIOPHYSICOCHEMICAL PROPERTIES:
pH dependence:
Broad optimum pH around 8.0.;
-!- SUBCELLULAR LOCATION: Lipid droplet {ECO:0000269|PubMed:16473965}.
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Note=Associates with the oil body membrane.
-!- DEVELOPMENTAL STAGE: Transcript levels increase at the beginning
of seed maturation and remain high until seed desiccation is
completed. High levels early in seed imbibition, but decline as
the seed germinates. {ECO:0000269|PubMed:16473965}.
-!- DISRUPTION PHENOTYPE: Not impaired in germination, but much slower
rate of postgerminative growth. {ECO:0000269|PubMed:16473965}.
-!- MISCELLANEOUS: Transcript levels do not correlate positively with
enzyme activity, suggesting a post-transcriptional regulation.
-!- SEQUENCE CAUTION:
Sequence=BAD94338.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AL162873; CAB85524.1; -; Genomic_DNA.
EMBL; CP002688; AED90687.1; -; Genomic_DNA.
EMBL; CP002688; ANM71199.1; -; Genomic_DNA.
EMBL; AY136470; AAM97135.1; -; mRNA.
EMBL; AK221922; BAD94338.1; ALT_INIT; mRNA.
PIR; T48431; T48431.
RefSeq; NP_001332745.1; NM_001342744.1.
RefSeq; NP_196024.1; NM_120486.7.
UniGene; At.24923; -.
ProteinModelPortal; Q9LZA6; -.
STRING; 3702.AT5G04040.1; -.
iPTMnet; Q9LZA6; -.
PaxDb; Q9LZA6; -.
PRIDE; Q9LZA6; -.
EnsemblPlants; AT5G04040.1; AT5G04040.1; AT5G04040.
EnsemblPlants; AT5G04040.2; AT5G04040.2; AT5G04040.
GeneID; 830283; -.
Gramene; AT5G04040.1; AT5G04040.1; AT5G04040.
Gramene; AT5G04040.2; AT5G04040.2; AT5G04040.
KEGG; ath:AT5G04040; -.
Araport; AT5G04040; -.
TAIR; locus:2150645; AT5G04040.
eggNOG; KOG2214; Eukaryota.
eggNOG; COG1752; LUCA.
HOGENOM; HOG000238293; -.
InParanoid; Q9LZA6; -.
KO; K14674; -.
OMA; CFHVGVV; -.
OrthoDB; EOG093603C0; -.
PhylomeDB; Q9LZA6; -.
BioCyc; ARA:AT5G04040-MONOMER; -.
BioCyc; MetaCyc:AT5G04040-MONOMER; -.
PRO; PR:Q9LZA6; -.
Proteomes; UP000006548; Chromosome 5.
ExpressionAtlas; Q9LZA6; baseline and differential.
Genevisible; Q9LZA6; AT.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0012511; C:monolayer-surrounded lipid storage body; IDA:TAIR.
GO; GO:0004806; F:triglyceride lipase activity; IDA:TAIR.
GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
GO; GO:0019433; P:triglyceride catabolic process; IMP:CACAO.
GO; GO:0006641; P:triglyceride metabolic process; IGI:TAIR.
InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
InterPro; IPR002641; PNPLA_dom.
InterPro; IPR021771; Triacylglycerol_lipase.
Pfam; PF11815; DUF3336; 1.
Pfam; PF01734; Patatin; 1.
SUPFAM; SSF52151; SSF52151; 1.
PROSITE; PS51635; PNPLA; 1.
1: Evidence at protein level;
Complete proteome; Glycerol metabolism; Glycoprotein; Hydrolase;
Lipid degradation; Lipid droplet; Lipid metabolism; Membrane;
Reference proteome; Transmembrane; Transmembrane helix.
CHAIN 1 825 Triacylglycerol lipase SDP1.
/FTId=PRO_0000398610.
TRANSMEM 231 248 Helical. {ECO:0000255}.
TRANSMEM 260 276 Helical. {ECO:0000255}.
DOMAIN 232 437 PNPLA. {ECO:0000255|PROSITE-
ProRule:PRU01161}.
MOTIF 263 267 GXSXG. {ECO:0000255|PROSITE-
ProRule:PRU01161}.
ACT_SITE 265 265 Nucleophile. {ECO:0000255|PROSITE-
ProRule:PRU01161}.
ACT_SITE 424 424 Proton acceptor. {ECO:0000255|PROSITE-
ProRule:PRU01161}.
CARBOHYD 129 129 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 327 327 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 331 331 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 601 601 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 616 616 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 637 637 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 800 800 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
MUTAGEN 241 241 G->D: In sdp1-3; loss of activity.
{ECO:0000269|PubMed:16473965}.
MUTAGEN 438 438 E->K: In sdp1-1; loss of activity.
{ECO:0000269|PubMed:16473965}.
MUTAGEN 456 456 P->S: In sdp1-2; loss of activity.
{ECO:0000269|PubMed:16473965}.
SEQUENCE 825 AA; 92092 MW; A80717BD5971F144 CRC64;
MDISNEASVD PFSIGPSSIM GRTIAFRVLF CRSMSQLRRD LFRFLLHWFL RFKLTVSPFV
SWFHPRNPQG ILAVVTIIAF VLKRYTNVKI KAEMAYRRKF WRNMMRTALT YEEWAHAAKM
LEKETPKMNE SDLYDEELVK NKLQELRHRR QEGSLRDIMF CMRADLVRNL GNMCNSELHK
GRLQVPRHIK EYIDEVSTQL RMVCNSDSEE LSLEEKLSFM HETRHAFGRT ALLLSGGASL
GAFHVGVVRT LVEHKLLPRI IAGSSVGSII CAVVASRSWP ELQSFFENSL HSLQFFDQLG
GVFSIVKRVM TQGALHDIRQ LQCMLRNLTS NLTFQEAYDM TGRILGITVC SPRKHEPPRC
LNYLTSPHVV IWSAVTASCA FPGLFEAQEL MAKDRSGEIV PYHPPFNLDP EVGTKSSSGR
RWRDGSLEVD LPMMQLKELF NVNHFIVSQA NPHIAPLLRL KDLVRAYGGR FAAKLAHLVE
MEVKHRCNQV LELGFPLGGL AKLFAQEWEG DVTVVMPATL AQYSKIIQNP THVELQKAAN
QGRRCTWEKL SAIKSNCGIE LALDDSVAIL NHMRRLKKSA ERAATATSSS HHGLASTTRF
NASRRIPSWN VLARENSTGS LDDLVTDNNL HASSGRNLSD SETESVELSS WTRTGGPLMR
TASANKFIDF VQSLDIDIAL VRGFSSSPNS PAVPPGGSFT PSPRSIAAHS DIESNSNSNN
LGTSTSSITV TEGDLLQPER TSNGFVLNVV KRENLGMPSI GNQNTELPES VQLDIPEKEM
DCSSVSEHEE DDNDNEEEHN GSSLVTVSSE DSGLQEPVSG SVIDA


Related products :

Catalog number Product name Quantity
30-475 PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The protein, which appears to be membrane bound, may be involved in the balance of energy usage_storage in ad 0.05 mg
U0769h CLIA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Homo sapiens,HTGL,Human,Lipase member C,LIPC 96T
E0769h ELISA kit Hepatic lipase,Hepatic triacylglycerol lipase,HL,Homo sapiens,HTGL,Human,Lipase member C,LIPC 96T
E0769h ELISA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Homo sapiens,HTGL,Human,Lipase member C,LIPC 96T
E0769Rb ELISA kit Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,LIPC,Oryctolagus cuniculus,Rabbit 96T
E0769Rb ELISA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,LIPC,Oryctolagus cuniculus,Rabbit 96T
U0769Rb CLIA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,LIPC,Oryctolagus cuniculus,Rabbit 96T
E0769m ELISA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Hpl,Lipase member C,Lipc,Mouse,Mus musculus 96T
U0769r CLIA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,Lipc,Rat,Rattus norvegicus 96T
E0769m ELISA kit Hepatic lipase,Hepatic triacylglycerol lipase,HL,Hpl,Lipase member C,Lipc,Mouse,Mus musculus 96T
U0769b CLIA Bos taurus,Bovine,Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,LIPC 96T
E0769b ELISA Bos taurus,Bovine,Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,LIPC 96T
E0769r ELISA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,Lipc,Rat,Rattus norvegicus 96T
E0769b ELISA kit Bos taurus,Bovine,Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,LIPC 96T
U0769m CLIA Hepatic lipase,Hepatic triacylglycerol lipase,HL,Hpl,Lipase member C,Lipc,Mouse,Mus musculus 96T
E0769r ELISA kit Hepatic lipase,Hepatic triacylglycerol lipase,HL,Lipase member C,Lipc,Rat,Rattus norvegicus 96T
E1453h ELISA kit Homo sapiens,Human,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL 96T
U1453h CLIA Homo sapiens,Human,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL 96T
E1453h ELISA Homo sapiens,Human,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL 96T
E1453Rb ELISA Oryctolagus cuniculus,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL,Rabbit 96T
E1453Rb ELISA kit Oryctolagus cuniculus,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL,Rabbit 96T
U1453Rb CLIA Oryctolagus cuniculus,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL,Rabbit 96T
524 LIPASE (TRIACYLGLYCEROL LIPASE), SERUM 1
E1453m ELISA Mouse,Mus musculus,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,Pnlip,PTL 96T
E1453r ELISA Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,Pnlip,Rat,Rattus norvegicus 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur