Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)

 TNR21_MOUSE             Reviewed;         655 AA.
Q9EPU5; Q3UYG3; Q543Y9; Q91W77; Q91XH9;
27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
27-MAY-2002, sequence version 2.
22-NOV-2017, entry version 144.
RecName: Full=Tumor necrosis factor receptor superfamily member 21;
AltName: Full=Death receptor 6;
AltName: CD_antigen=CD358;
Flags: Precursor;
Name=Tnfrsf21; Synonyms=Dr6;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=C57BL/6J; TISSUE=Kidney;
Isogai D., Ichino M., Yoshinari M., Yamaura A., Kurokawa F.,
Minami M.;
"Mouse DR6: mouse homolog of human TNFR-related death receptor-6
(DR6).";
Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=BALB/cJ; TISSUE=Kidney;
Kim V., Machleidt T., Shi W.-X., Wang X., Cai Z.;
"Murine DR6: murine TNFR-related death receptor-6.";
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J; TISSUE=Brain cortex, and Medulla oblongata;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Kidney;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[5]
FUNCTION, DISRUPTION PHENOTYPE, AND TISSUE SPECIFICITY.
PubMed=11485735; DOI=10.1016/S1074-7613(01)00162-5;
Liu J., Na S., Glasebrook A., Fox N., Solenberg P.J., Zhang Q.,
Song H.Y., Yang D.D.;
"Enhanced CD4+ T cell proliferation and Th2 cytokine production in
DR6-deficient mice.";
Immunity 15:23-34(2001).
[6]
FUNCTION, DISRUPTION PHENOTYPE, AND TISSUE SPECIFICITY.
PubMed=11714751; DOI=10.1084/jem.194.10.1441;
Zhao H., Yan M., Wang H., Erickson S., Grewal I.S., Dixit V.M.;
"Impaired c-Jun amino terminal kinase activity and T cell
differentiation in death receptor 6-deficient mice.";
J. Exp. Med. 194:1441-1448(2001).
[7]
FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, AND TISSUE
SPECIFICITY.
PubMed=12515813; DOI=10.1084/jem.20020617;
Schmidt C.S., Liu J., Zhang T., Song H.Y., Sandusky G., Mintze K.,
Benschop R.J., Glasebrook A., Yang D.D., Na S.;
"Enhanced B cell expansion, survival, and humoral responses by
targeting death receptor 6.";
J. Exp. Med. 197:51-62(2003).
[8]
FUNCTION, TISSUE SPECIFICITY, AND INTERACTION WITH APP.
PubMed=19225519; DOI=10.1038/nature07767;
Nikolaev A., McLaughlin T., O'Leary D.D.M., Tessier-Lavigne M.;
"APP binds DR6 to trigger axon pruning and neuron death via distinct
caspases.";
Nature 457:981-989(2009).
[9]
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Brain;
PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
"A tissue-specific atlas of mouse protein phosphorylation and
expression.";
Cell 143:1174-1189(2010).
[10]
FUNCTION, AND DISRUPTION PHENOTYPE.
PubMed=21725297; DOI=10.1038/nm.2373;
Mi S., Lee X., Hu Y., Ji B., Shao Z., Yang W., Huang G., Walus L.,
Rhodes K., Gong B.J., Miller R.H., Pepinsky R.B.;
"Death receptor 6 negatively regulates oligodendrocyte survival,
maturation and myelination.";
Nat. Med. 17:816-821(2011).
[11]
FUNCTION, AND DISRUPTION PHENOTYPE.
PubMed=23559013; DOI=10.1038/cddis.2013.110;
Hu Y., Lee X., Shao Z., Apicco D., Huang G., Gong B.J., Pepinsky R.B.,
Mi S.;
"A DR6/p75(NTR) complex is responsible for beta-amyloid-induced
cortical neuron death.";
Cell Death Dis. 4:E579-E579(2013).
-!- FUNCTION: Promotes apoptosis, possibly via a pathway that involves
the activation of NF-kappa-B. Can also promote apoptosis mediated
by BAX and by the release of cytochrome c from the mitochondria
into the cytoplasm. Plays a role in neuronal apoptosis, including
apoptosis in response to amyloid peptides derived from APP, and is
required for both normal cell body death and axonal pruning.
Trophic-factor deprivation triggers the cleavage of surface APP by
beta-secretase to release sAPP-beta which is further cleaved to
release an N-terminal fragment of APP (N-APP). N-APP binds
TNFRSF21; this triggers caspase activation and degeneration of
both neuronal cell bodies (via caspase-3) and axons (via caspase-
6). Negatively regulates oligodendrocyte survival, maturation and
myelination. Plays a role in signaling cascades triggered by
stimulation of T-cell receptors, in the adaptive immune response
and in the regulation of T-cell differentiation and proliferation.
Negatively regulates T-cell responses and the release of cytokines
such as IL4, IL5, IL10, IL13 and IFNG by Th2 cells. Negatively
regulates the production of IgG, IgM and IgM in response to
antigens. May inhibit the activation of JNK in response to T-cell
stimulation. {ECO:0000269|PubMed:11485735,
ECO:0000269|PubMed:11714751, ECO:0000269|PubMed:12515813,
ECO:0000269|PubMed:19225519, ECO:0000269|PubMed:21725297,
ECO:0000269|PubMed:23559013}.
-!- SUBUNIT: Associates with TRADD. Interacts with NGFR (By
similarity). Interacts with N-APP. {ECO:0000250,
ECO:0000269|PubMed:19225519}.
-!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:12515813};
Single-pass type I membrane protein {ECO:0000269|PubMed:12515813}.
-!- TISSUE SPECIFICITY: Detected in spleen B-cells (at protein level).
Ubiquitous. Highly expressed in adult spleen, thymus, testis,
prostate, ovary, small intestine, colon, brain, lung and kidney,
and in fetal brain, liver and lung. Detected at lower levels in
adult peripheral blood leukocytes, lung, and in fetal muscle,
heart, kidney, small intestine and skin. Detected in T-cells, B-
cells and monocytes. In T-cells expression is highest in Th0
cells, intermediate in Th2 cells and lower in Th1 cells. Expressed
at low levels in proliferating progenitors in the spinal cord, but
is highly expressed by differentiating neurons within the spinal
cord and adjacent dorsal root ganglia. Expressed by developing
neurons as they differentiate and enter a pro-apoptotic state.
Expressed by both cell bodies and axons.
{ECO:0000269|PubMed:11485735, ECO:0000269|PubMed:11714751,
ECO:0000269|PubMed:12515813, ECO:0000269|PubMed:19225519}.
-!- DISRUPTION PHENOTYPE: No visible phenotype. Mice are born at the
expected Mendelian rate, are viable and fertile. Mutant mice
display an increased number of T-cells in the peripheral blood,
but only a minor increase of the number of T-cells in spleen and
thymus. T-cells from mutant mice show increased proliferative
responses to antigens and produce higher levels of IL4, IL5, IL10,
IL13 and IFNG. Mutant mice have normal serum levels of IgG and IgM
in the absence of antigen, but produce higher levels of IgG, IgM
and IgM in response to antigens. Likewise, B-cells from mutant
mice display increased proliferation and decreased apoptosis in
response to antigens. Mutant mice show increased levels of mature
oligodendrocytes, decreased levels of apoptotic oligodendrocytes
and increased myelination. Mutant mice are not susceptible to
neuronal apoptosis triggered by exposure to amyloid peptides
derived from APP. {ECO:0000269|PubMed:11485735,
ECO:0000269|PubMed:11714751, ECO:0000269|PubMed:12515813,
ECO:0000269|PubMed:21725297, ECO:0000269|PubMed:23559013}.
-!- CAUTION: It is uncertain whether Met-1 or Met-25 is the initiator.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AF322069; AAG38115.1; -; mRNA.
EMBL; AY043489; AAK74193.1; -; mRNA.
EMBL; AK043823; BAC31664.1; -; mRNA.
EMBL; AK134704; BAE22249.1; -; mRNA.
EMBL; BC016420; AAH16420.1; -; mRNA.
CCDS; CCDS28794.1; -.
RefSeq; NP_848704.1; NM_178589.3.
UniGene; Mm.200792; -.
PDB; 4YN0; X-ray; 2.20 A; A=42-220.
PDBsum; 4YN0; -.
ProteinModelPortal; Q9EPU5; -.
SMR; Q9EPU5; -.
DIP; DIP-59733N; -.
IntAct; Q9EPU5; 2.
STRING; 10090.ENSMUSP00000024708; -.
iPTMnet; Q9EPU5; -.
PhosphoSitePlus; Q9EPU5; -.
MaxQB; Q9EPU5; -.
PaxDb; Q9EPU5; -.
PRIDE; Q9EPU5; -.
Ensembl; ENSMUST00000024708; ENSMUSP00000024708; ENSMUSG00000023915.
GeneID; 94185; -.
KEGG; mmu:94185; -.
UCSC; uc008cov.1; mouse.
CTD; 27242; -.
MGI; MGI:2151075; Tnfrsf21.
eggNOG; ENOG410IHQ6; Eukaryota.
eggNOG; ENOG410YYKW; LUCA.
GeneTree; ENSGT00760000119204; -.
HOGENOM; HOG000136852; -.
HOVERGEN; HBG054218; -.
InParanoid; Q9EPU5; -.
KO; K05157; -.
OMA; LMEDTAQ; -.
OrthoDB; EOG091G03XW; -.
PhylomeDB; Q9EPU5; -.
TreeFam; TF331157; -.
ChiTaRS; Tnfrsf21; mouse.
PRO; PR:Q9EPU5; -.
Proteomes; UP000000589; Chromosome 17.
Bgee; ENSMUSG00000023915; -.
Genevisible; Q9EPU5; MM.
GO; GO:0030424; C:axon; IDA:UniProtKB.
GO; GO:0005887; C:integral component of plasma membrane; ISO:MGI.
GO; GO:0031226; C:intrinsic component of plasma membrane; IDA:UniProtKB.
GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; IBA:GO_Central.
GO; GO:0002250; P:adaptive immune response; IMP:UniProtKB.
GO; GO:0006915; P:apoptotic process; ISO:MGI.
GO; GO:0097190; P:apoptotic signaling pathway; IBA:GO_Central.
GO; GO:0001783; P:B cell apoptotic process; IMP:UniProtKB.
GO; GO:0071356; P:cellular response to tumor necrosis factor; ISO:MGI.
GO; GO:0006959; P:humoral immune response; IMP:UniProtKB.
GO; GO:0006954; P:inflammatory response; IBA:GO_Central.
GO; GO:0042552; P:myelination; IMP:UniProtKB.
GO; GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.
GO; GO:2001180; P:negative regulation of interleukin-10 secretion; IMP:UniProtKB.
GO; GO:2000666; P:negative regulation of interleukin-13 secretion; IMP:UniProtKB.
GO; GO:2000663; P:negative regulation of interleukin-5 secretion; IMP:UniProtKB.
GO; GO:0031642; P:negative regulation of myelination; ISO:MGI.
GO; GO:0042130; P:negative regulation of T cell proliferation; IMP:UniProtKB.
GO; GO:0051402; P:neuron apoptotic process; IMP:UniProtKB.
GO; GO:0097252; P:oligodendrocyte apoptotic process; IMP:UniProtKB.
GO; GO:0042981; P:regulation of apoptotic process; IBA:GO_Central.
GO; GO:0048713; P:regulation of oligodendrocyte differentiation; IMP:UniProtKB.
GO; GO:0032496; P:response to lipopolysaccharide; IBA:GO_Central.
GO; GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.
CDD; cd08778; Death_TNFRSF21; 1.
CDD; cd10583; TNFRSF21; 1.
InterPro; IPR011029; DEATH-like_dom_sf.
InterPro; IPR000488; Death_domain.
InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
InterPro; IPR022330; TNFR_21.
InterPro; IPR034037; TNFRSF21_death.
InterPro; IPR034034; TNFRSF21_N.
InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
Pfam; PF00531; Death; 1.
Pfam; PF00020; TNFR_c6; 2.
PRINTS; PR01971; TNFACTORR21.
SMART; SM00005; DEATH; 1.
SMART; SM01411; Ephrin_rec_like; 2.
SMART; SM00208; TNFR; 4.
SUPFAM; SSF47986; SSF47986; 1.
PROSITE; PS50017; DEATH_DOMAIN; 1.
PROSITE; PS00652; TNFR_NGFR_1; 1.
PROSITE; PS50050; TNFR_NGFR_2; 1.
1: Evidence at protein level;
3D-structure; Adaptive immunity; Apoptosis; Cell membrane;
Complete proteome; Disulfide bond; Glycoprotein; Immunity;
Lipoprotein; Membrane; Palmitate; Receptor; Reference proteome;
Repeat; Signal; Transmembrane; Transmembrane helix.
SIGNAL 1 41 {ECO:0000255}.
CHAIN 42 655 Tumor necrosis factor receptor
superfamily member 21.
/FTId=PRO_0000034603.
TOPO_DOM 42 349 Extracellular. {ECO:0000255}.
TRANSMEM 350 370 Helical. {ECO:0000255}.
TOPO_DOM 371 655 Cytoplasmic. {ECO:0000255}.
REPEAT 50 88 TNFR-Cys 1.
REPEAT 90 131 TNFR-Cys 2.
REPEAT 133 167 TNFR-Cys 3.
REPEAT 170 211 TNFR-Cys 4.
DOMAIN 415 498 Death. {ECO:0000255|PROSITE-
ProRule:PRU00064}.
LIPID 368 368 S-palmitoyl cysteine. {ECO:0000250}.
CARBOHYD 82 82 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 141 141 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 252 252 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 257 257 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 278 278 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 289 289 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 67 80 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 70 88 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 91 106 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 109 123 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 113 131 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 133 144 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 150 168 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 171 186 {ECO:0000255|PROSITE-ProRule:PRU00206}.
DISULFID 192 211 {ECO:0000255|PROSITE-ProRule:PRU00206}.
CONFLICT 93 93 A -> T (in Ref. 3; BAE22249).
{ECO:0000305}.
CONFLICT 352 352 W -> L (in Ref. 1; AAG38115).
{ECO:0000305}.
CONFLICT 523 523 M -> I (in Ref. 4; AAH16420).
{ECO:0000305}.
STRAND 53 57 {ECO:0000244|PDB:4YN0}.
TURN 59 61 {ECO:0000244|PDB:4YN0}.
STRAND 64 68 {ECO:0000244|PDB:4YN0}.
STRAND 74 78 {ECO:0000244|PDB:4YN0}.
STRAND 82 84 {ECO:0000244|PDB:4YN0}.
STRAND 87 90 {ECO:0000244|PDB:4YN0}.
STRAND 118 121 {ECO:0000244|PDB:4YN0}.
STRAND 130 132 {ECO:0000244|PDB:4YN0}.
STRAND 137 140 {ECO:0000244|PDB:4YN0}.
STRAND 143 146 {ECO:0000244|PDB:4YN0}.
STRAND 154 158 {ECO:0000244|PDB:4YN0}.
STRAND 162 164 {ECO:0000244|PDB:4YN0}.
STRAND 167 170 {ECO:0000244|PDB:4YN0}.
STRAND 181 183 {ECO:0000244|PDB:4YN0}.
HELIX 193 195 {ECO:0000244|PDB:4YN0}.
STRAND 198 201 {ECO:0000244|PDB:4YN0}.
STRAND 205 207 {ECO:0000244|PDB:4YN0}.
STRAND 210 212 {ECO:0000244|PDB:4YN0}.
SEQUENCE 655 AA; 71983 MW; 5EC7C51C7C99EFF7 CRC64;
MGTRASSITA LASCSRTAGQ VGATMVAGSL LLLGFLSTIT AQPEQKTLSL PGTYRHVDRT
TGQVLTCDKC PAGTYVSEHC TNMSLRVCSS CPAGTFTRHE NGIERCHDCS QPCPWPMIER
LPCAALTDRE CICPPGMYQS NGTCAPHTVC PVGWGVRKKG TENEDVRCKQ CARGTFSDVP
SSVMKCKAHT DCLGQNLEVV KPGTKETDNV CGMRLFFSST NPPSSGTVTF SHPEHMESHD
VPSSTYEPQG MNSTDSNSTA SVRTKVPSGI EEGTVPDNTS STSGKEGTNR TLPNPPQVTH
QQAPHHRHIL KLLPSSMEAT GEKSSTAIKA PKRGHPRQNA HKHFDINEHL PWMIVLFLLL
VLVLIVVCSI RKSSRTLKKG PRQDPSAIVE KAGLKKSLTP TQNREKWIYY RNGHGIDILK
LVAAQVGSQW KDIYQFLCNA SEREVAAFSN GYTADHERAY AALQHWTIRG PEASLAQLIS
ALRQHRRNDV VEKIRGLMED TTQLETDKLA LPMSPSPLSP SPMPSPNVKL ENSTLLTVEP
SPLDKNKCFF VDESEPLLRC DSTSSGSSAL SRNGSFITKE KKDTVLRQVR LDPCDLQPIF
DDMLHILNPE ELRVIEEIPQ AEDKLDRLFE IIGVKSQEAS QTLLDSVYSH LPDLL


Related products :

Catalog number Product name Quantity
18-661-15036 Tumor necrosis factor receptor superfamily member 10B - Death receptor 5; TNF-related apoptosis-inducing ligand receptor 2; TRAIL receptor 2; TRAIL-R2; CD262 antigen Polyclonal 0.1 mg
18-661-15019 Tumor necrosis factor receptor superfamily member 10A - Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD261 antigen Polyclonal 0.1 mg
18-001-30087 Tumor necrosis factor receptor superfamily member 10B - Death receptor 5; TNF-related apoptosis-inducing ligand receptor 2; TRAIL receptor 2; TRAIL-R2; CD262 antigen Polyclonal 0.1 mg
18-003-42886 Tumor necrosis factor receptor superfamily member 10A - Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD261 antigen Polyclonal 0.1 mg Protein A
U0131h CLIA Homo sapiens,Human,p55,p60,TNFAR,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
E0131h ELISA Homo sapiens,Human,p55,p60,TNFAR,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
U0132h CLIA Homo sapiens,Human,p75,p80 TNF-alpha receptor,TNFBR,TNFR2,TNF-R2,TNF-RII,TNFR-II,TNFRSF1B,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis fact 96T
E0131h ELISA kit Homo sapiens,Human,p55,p60,TNFAR,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor typ 96T
E0132h ELISA Homo sapiens,Human,p75,p80 TNF-alpha receptor,TNFBR,TNFR2,TNF-R2,TNF-RII,TNFR-II,TNFRSF1B,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis fac 96T
EIAAB43343 Death receptor 6,Dr6,Mouse,Mus musculus,Tnfrsf21,Tumor necrosis factor receptor superfamily member 21
E0131b ELISA Bos taurus,Bovine,p55,p60,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
U0131b CLIA Bos taurus,Bovine,p55,p60,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
E0131b ELISA kit Bos taurus,Bovine,p55,p60,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
E0132r ELISA p75,p80 TNF-alpha receptor,Rat,Rattus norvegicus,Tnfr2,TNF-R2,TNF-RII,TNFR-II,Tnfrsf1b,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor 96T
U0132r CLIA p75,p80 TNF-alpha receptor,Rat,Rattus norvegicus,Tnfr2,TNF-R2,TNF-RII,TNFR-II,Tnfrsf1b,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor 96T
EIAAB43687 Death receptor 5,Dr5,Killer,MK,Mouse,Mus musculus,Tnfrsf10b,Tumor necrosis factor receptor superfamily member 10B
15-288-21065 Tumor necrosis factor receptor superfamily member 3 - Lymphotoxin-beta receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor C receptor Polyclonal 0.05 mg
15-288-21065 Tumor necrosis factor receptor superfamily member 3 - Lymphotoxin-beta receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor C receptor Polyclonal 0.1 mg
E0132r ELISA kit p75,p80 TNF-alpha receptor,Rat,Rattus norvegicus,Tnfr2,TNF-R2,TNF-RII,TNFR-II,Tnfrsf1b,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis f 96T
EIAAB43344 Death receptor 6,DR6,Homo sapiens,Human,TNFRSF21,Tumor necrosis factor receptor superfamily member 21,UNQ437_PRO868
E0131p ELISA kit p55,p60,Pig,Sus scrofa,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
E0131p ELISA p55,p60,Pig,Sus scrofa,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
U0131p CLIA p55,p60,Pig,Sus scrofa,TNFR1,TNF-R1,TNF-RI,TNFR-I,TNFRSF1A,Tumor necrosis factor receptor 1,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I 96T
18-661-15037 Tumor necrosis factor receptor superfamily member 10D - Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death doma 0.1 mg
EIAAB43686 APO2,Death receptor 4,DR4,Homo sapiens,Human,TNF-related apoptosis-inducing ligand receptor 1,TNFRSF10A,TRAIL receptor 1,TRAILR1,TRAIL-R1,Tumor necrosis factor receptor superfamily member 10A


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur