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Tumor necrosis factor superfamily member 12

 S4S352_ELADA            Unreviewed;       248 AA.
S4S352;
16-OCT-2013, integrated into UniProtKB/TrEMBL.
16-OCT-2013, sequence version 1.
10-MAY-2017, entry version 13.
SubName: Full=Tumor necrosis factor superfamily member 12 {ECO:0000313|EMBL:AEG64805.1};
Name=Tweak {ECO:0000313|EMBL:AEG64805.1};
Elaphurus davidianus (Pere David's deer).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Cervidae; Cervinae; Elaphurus.
NCBI_TaxID=43332 {ECO:0000313|EMBL:AEG64805.1};
[1] {ECO:0000313|EMBL:AEG64805.1}
NUCLEOTIDE SEQUENCE.
Han Y.Y., Chen Y.Q., Liu H.Y.;
"Molecular characterization of the Pere David's deer cytokine TWEAK
and its receptor, Fn14.";
Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
-!- SIMILARITY: Belongs to the tumor necrosis factor family.
{ECO:0000256|SAAS:SAAS00758062}.
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EMBL; JF747147; AEG64805.1; -; mRNA.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
GO; GO:0006955; P:immune response; IEA:InterPro.
Gene3D; 2.60.120.40; -; 1.
InterPro; IPR006052; TNF_dom.
InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
Pfam; PF00229; TNF; 1.
SMART; SM00207; TNF; 1.
SUPFAM; SSF49842; SSF49842; 1.
PROSITE; PS50049; TNF_2; 1.
2: Evidence at transcript level;
Membrane {ECO:0000256|SAM:Phobius};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 20 44 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 107 247 TNF_2. {ECO:0000259|PROSITE:PS50049}.
SEQUENCE 248 AA; 27159 MW; 194590C2DCE239CC CRC64;
MASRRIQSRR ERRGEPGTAL LAPLVLGLGL VLACLGLLLA VVSLGSRASL FAQEPSQRDL
VAEEDPDPLD LNPQPEESQD AVPFLKLVRP RRNASKGRKP RACRAVAAHY EVHPQPGQDG
AQAGVDGTVS GWEEAKINSS NPLRYDCQTG QFMVTLAGLY YLYCQVHFDE GKAVYLKLDL
LVDDTLALRC LEEFSATAAS SPGPQLRLCQ VSGLLRLRRG SSLRIRTLPQ TQLKAAPFLT
YLGLFQVH


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