Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase)

 GPT_CRIGR               Reviewed;         408 AA.
P24140;
01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
01-MAR-1992, sequence version 1.
12-SEP-2018, entry version 83.
RecName: Full=UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase;
EC=2.7.8.15;
AltName: Full=GlcNAc-1-P transferase;
Short=G1PT;
Short=GPT;
AltName: Full=N-acetylglucosamine-1-phosphate transferase;
Name=DPAGT1; Synonyms=DPAGT2, GNPTA, GTR2;
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Cricetidae; Cricetinae; Cricetulus.
NCBI_TaxID=10029;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Ovary;
PubMed=1700792;
Scocca J.R., Krag S.S.;
"Sequence of a cDNA that specifies the uridine diphosphate N-acetyl-D-
glucosamine:dolichol phosphate N-acetylglucosamine-1-phosphate
transferase from Chinese hamster ovary cells.";
J. Biol. Chem. 265:20621-20626(1990).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
PubMed=7772861; DOI=10.1093/glycob/5.1.129;
Scocca J.R., Zou J., Krag S.S.;
"Genomic organization and expression of hamster UDP-N-
acetylglucosamine:dolichyl phosphate N-acetylglucosaminyl phosphoryl
transferase.";
Glycobiology 5:129-136(1995).
-!- FUNCTION: Catalyzes the initial step of dolichol-linked
oligosaccharide biosynthesis in N-linked protein glycosylation
pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier
lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-
dolichol. {ECO:0000250|UniProtKB:Q9H3H5}.
-!- CATALYTIC ACTIVITY: UDP-N-acetyl-D-glucosamine + dolichyl
phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.
-!- COFACTOR:
Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
Evidence={ECO:0000250|UniProtKB:Q9H3H5};
-!- ACTIVITY REGULATION: Activated by mannosylphosphoryldolichol and
phospholipids such as phosphatidylglycerol and
phosphatidylcholine. Inhibited by natural nucleoside antibiotic
tunicamycin, which acts as a structural analog and competitor of
UDP-GlcNAc. {ECO:0000250|UniProtKB:Q9H3H5}.
-!- PATHWAY: Protein modification; protein glycosylation.
-!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:Q9H3H5}.
-!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
{ECO:0000250|UniProtKB:Q9H3H5}; Multi-pass membrane protein
{ECO:0000250|UniProtKB:Q9H3H5}.
-!- SIMILARITY: Belongs to the glycosyltransferase 4 family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; M36899; AAA37027.1; -; mRNA.
EMBL; U15161; AAA51872.1; -; Genomic_DNA.
EMBL; U09453; AAA85220.1; -; Genomic_DNA.
RefSeq; NP_001230970.1; NM_001244041.1.
SMR; P24140; -.
PRIDE; P24140; -.
GeneID; 100689054; -.
KEGG; cge:100689054; -.
CTD; 1798; -.
HOVERGEN; HBG000846; -.
KO; K01001; -.
UniPathway; UPA00378; -.
GO; GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.
GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IDA:UniProtKB.
GO; GO:0016021; C:integral component of membrane; IDA:UniProtKB.
GO; GO:0008963; F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity; IEA:InterPro.
GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
GO; GO:0003975; F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity; IMP:UniProtKB.
GO; GO:0003976; F:UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; IEA:Ensembl.
GO; GO:0019408; P:dolichol biosynthetic process; IMP:UniProtKB.
GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.
GO; GO:0051259; P:protein complex oligomerization; IDA:UniProtKB.
CDD; cd06855; GT_GPT_euk; 1.
InterPro; IPR000715; Glycosyl_transferase_4.
InterPro; IPR033895; GPT.
PANTHER; PTHR10571; PTHR10571; 1.
Pfam; PF00953; Glycos_transf_4; 1.
2: Evidence at transcript level;
Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Magnesium;
Membrane; Transferase; Transmembrane; Transmembrane helix.
CHAIN 1 408 UDP-N-acetylglucosamine--dolichyl-
phosphate N-
acetylglucosaminephosphotransferase.
/FTId=PRO_0000108760.
TOPO_DOM 1 10 Lumenal. {ECO:0000305}.
TRANSMEM 11 38 Helical; Name=Helix 1.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 39 58 Cytoplasmic. {ECO:0000305}.
TRANSMEM 59 78 Helical; Name=Helix 2.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 79 91 Lumenal. {ECO:0000305}.
TRANSMEM 92 118 Helical; Name=Helix 3.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 119 121 Cytoplasmic. {ECO:0000305}.
TRANSMEM 122 143 Helical; Name=Helix 4.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 144 166 Lumenal. {ECO:0000305}.
TRANSMEM 167 186 Helical; Name=Helix 5.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 187 192 Cytoplasmic. {ECO:0000305}.
TRANSMEM 193 213 Helical; Name=Helix 6.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 214 218 Lumenal. {ECO:0000305}.
TRANSMEM 219 242 Helical; Name=Helix 7.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 243 250 Cytoplasmic. {ECO:0000305}.
TRANSMEM 251 269 Helical; Name=Helix 8.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 270 271 Lumenal. {ECO:0000305}.
TRANSMEM 272 293 Helical; Name=Helix 9.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 294 375 Cytoplasmic. {ECO:0000305}.
TRANSMEM 376 400 Helical; Name=Helix 10.
{ECO:0000250|UniProtKB:Q9H3H5}.
TOPO_DOM 401 408 Lumenal. {ECO:0000305}.
MOTIF 67 79 Dolichol recognition.
MOTIF 222 234 Dolichol recognition.
BINDING 46 46 Inhibitor; via amide nitrogen.
{ECO:0000250|UniProtKB:Q9H3H5}.
BINDING 119 119 Inhibitor.
{ECO:0000250|UniProtKB:Q9H3H5}.
BINDING 185 185 Inhibitor.
{ECO:0000250|UniProtKB:Q9H3H5}.
BINDING 252 252 Inhibitor.
{ECO:0000250|UniProtKB:Q9H3H5}.
BINDING 303 303 Inhibitor.
{ECO:0000250|UniProtKB:Q9H3H5}.
CARBOHYD 146 146 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
SEQUENCE 408 AA; 46250 MW; CB0FF5946C07BEF3 CRC64;
MWAFPELPLP LLVNLFGSLL GFVATVTLIP AFRSHFIAAR LCGQDLNKLS RQQIPESQGV
ICGAVFLIIL FCFIPFPFLN CFVEEQCKAF PHHEFVALIG ALLAICCMIF LGFADDVLNL
RWRHKLLLPT AASLPLLMVY FTNFGNTTIV VPKPFRWILG LHLDLGILYY VYMGLLAVFC
TNAINILAGI NGLEAGQSLV ISASIIVFNL VELEGDYRDD HVFSLYFMIP FFFTTLGLLY
HNWYPSQVFV GDTFCYFAGM TFAVVGILGH FSKTMLLFFI PQVFNFLYSL PQLLHAIPCP
RHRIPRLNPK TGKLEMSYSK FKTKNLSFLG TFILKVAERL QLVTVHRGES EDGAFTECNN
MTLINLLLKI FGPIHERNLT LLLLLLQILS SAVTFSIRYQ LVRLFYDV


Related products :

Catalog number Product name Quantity
DPCR1 DPAGT1 Gene dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
CSB-EL007121MO Mouse dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (DPAGT1) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
CSB-EL007121HU Human dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (DPAGT1) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL007121BO Bovine dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (DPAGT1) ELISA kit, Species Bovine, Sample Type serum, plasma 96T
CSB-EL016315PI Pig O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine polypeptide-N-acetylglucosaminyl transferase) (OGT) ELISA kit, Species Pig, Sample Type serum, plasma 96T
CSB-EL016315RA Rat O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine polypeptide-N-acetylglucosaminyl transferase) (OGT) ELISA kit, Species Rat, Sample Type serum, plasma 96T
OIP5 OGT Gene O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine polypeptide-N-acetylglucosaminyl transferase)
CSB-EL016315HU Human O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine polypeptide-N-acetylglucosaminyl transferase) (OGT) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL016315MO Mouse O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine polypeptide-N-acetylglucosaminyl transferase) (OGT) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
CSB-EL016315RB Rabbit O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine polypeptide-N-acetylglucosaminyl transferase) (OGT) ELISA kit, Species Rabbit, Sample Type serum, plasma 96T
GPT_MOUSE Mouse ELISA Kit FOR UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 96T
EIAAB28728 O-GlcNAc transferase subunit p110,OGT,O-linked N-acetylglucosamine transferase 110 kDa subunit,Oryctolagus cuniculus,Rabbit,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa sub
CSB-EL007121BO Bovine UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit 96T
CSB-EL007121MO Mouse UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit 96T
I0600 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1), Mouse, ELISA Kit 96T
CSB-EL007121HU Human UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit 96T
I0598 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1), Bovine, ELISA Kit 96T
I0599 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1), Human, ELISA Kit 96T
CSB-EL007121MO Mouse UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit SpeciesMouse 96T
CSB-EL007121HU Human UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit SpeciesHuman 96T
CSB-EL007121BO Bovine UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit SpeciesBovine 96T
EIAAB28725 Homo sapiens,Human,O-GlcNAc transferase subunit p110,OGT,O-linked N-acetylglucosamine transferase 110 kDa subunit,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
EIAAB28729 Mouse,Mus musculus,O-GlcNAc transferase subunit p110,Ogt,O-linked N-acetylglucosamine transferase 110 kDa subunit,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
EIAAB28727 O-GlcNAc transferase subunit p110,Ogt,O-linked N-acetylglucosamine transferase 110 kDa subunit,Rat,Rattus norvegicus,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
CSB-PA016315GA01HU Rabbit anti-human O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) polyclonal Antibody Primary antibody Host:Rabbit IgG 150ul


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur