Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) (D-glutamic acid-adding enzyme) (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase)

 F7XVN9_MIDMI            Unreviewed;       461 AA.
F7XVN9;
21-SEP-2011, integrated into UniProtKB/TrEMBL.
21-SEP-2011, sequence version 1.
27-SEP-2017, entry version 46.
RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase {ECO:0000256|HAMAP-Rule:MF_00639, ECO:0000256|SAAS:SAAS00382177};
EC=6.3.2.9 {ECO:0000256|HAMAP-Rule:MF_00639, ECO:0000256|SAAS:SAAS00382044};
AltName: Full=D-glutamic acid-adding enzyme {ECO:0000256|HAMAP-Rule:MF_00639};
AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase {ECO:0000256|HAMAP-Rule:MF_00639};
Name=mraY {ECO:0000313|EMBL:AEI88738.1};
Synonyms=murD {ECO:0000256|HAMAP-Rule:MF_00639};
OrderedLocusNames=midi_00431 {ECO:0000313|EMBL:AEI88738.1};
Midichloria mitochondrii (strain IricVA).
Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
Candidatus Midichloriaceae; Candidatus Midichloria.
NCBI_TaxID=696127 {ECO:0000313|EMBL:AEI88738.1, ECO:0000313|Proteomes:UP000006639};
[1] {ECO:0000313|EMBL:AEI88738.1, ECO:0000313|Proteomes:UP000006639}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=IricVA {ECO:0000313|EMBL:AEI88738.1,
ECO:0000313|Proteomes:UP000006639};
PubMed=21690562; DOI=10.1093/molbev/msr159;
Sassera D., Lo N., Epis S., D'Auria G., Montagna M., Comandatore F.,
Horner D., Pereto J., Luciano A.M., Franciosi F., Ferri E., Crotti E.,
Bazzocchi C., Daffonchio D., Sacchi L., Moya A., Latorre A., Bandi C.;
"Phylogenomic evidence for the presence of a flagellum and cbb3
oxidase in the free-living mitochondrial ancestor.";
Mol. Biol. Evol. 28:3285-3296(2011).
-!- FUNCTION: Cell wall formation. Catalyzes the addition of glutamate
to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
{ECO:0000256|HAMAP-Rule:MF_00639, ECO:0000256|SAAS:SAAS00382010}.
-!- CATALYTIC ACTIVITY: ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine
+ D-glutamate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-
alanyl-D-glutamate. {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00382107}.
-!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
{ECO:0000256|HAMAP-Rule:MF_00639, ECO:0000256|SAAS:SAAS00382165}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084461}.
-!- SIMILARITY: Belongs to the MurCDEF family. {ECO:0000256|HAMAP-
Rule:MF_00639, ECO:0000256|SAAS:SAAS00569906}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; CP002130; AEI88738.1; -; Genomic_DNA.
RefSeq; WP_013950950.1; NC_015722.1.
STRING; 696127.midi_00431; -.
EnsemblBacteria; AEI88738; AEI88738; midi_00431.
KEGG; mmn:midi_00431; -.
eggNOG; ENOG4105DMZ; Bacteria.
eggNOG; COG0771; LUCA.
KO; K01925; -.
OMA; LWVDDSK; -.
OrthoDB; POG091H002Z; -.
UniPathway; UPA00219; -.
Proteomes; UP000006639; Chromosome.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
GO; GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:InterPro.
GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO; GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:UniProtKB-UniRule.
GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniRule.
GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
Gene3D; 3.40.1190.10; -; 1.
HAMAP; MF_00639; MurD; 1.
InterPro; IPR018109; Folylpolyglutamate_synth_CS.
InterPro; IPR004101; Mur_ligase_C.
InterPro; IPR013221; Mur_ligase_cen.
InterPro; IPR005762; UDP-N-AcMur-Glu_ligase.
Pfam; PF08245; Mur_ligase_M; 1.
SUPFAM; SSF53244; SSF53244; 1.
SUPFAM; SSF53623; SSF53623; 1.
TIGRFAMs; TIGR01087; murD; 1.
PROSITE; PS01011; FOLYLPOLYGLU_SYNT_1; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084371};
Cell cycle {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084380};
Cell division {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084380};
Cell shape {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084414};
Cell wall biogenesis/degradation {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00459111};
Complete proteome {ECO:0000313|Proteomes:UP000006639};
Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084399};
Ligase {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084447};
Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084371};
Peptidoglycan synthesis {ECO:0000256|HAMAP-Rule:MF_00639,
ECO:0000256|SAAS:SAAS00084414};
Reference proteome {ECO:0000313|Proteomes:UP000006639};
Transferase {ECO:0000313|EMBL:AEI88738.1}.
DOMAIN 123 301 Mur_ligase_M. {ECO:0000259|Pfam:PF08245}.
NP_BIND 125 131 ATP. {ECO:0000256|HAMAP-Rule:MF_00639}.
SEQUENCE 461 AA; 51473 MW; FAD986D198BDB17E CRC64;
MIKFDNYSDR LIGILGLAKS GKAAINSFIE RGAQIVAWDD NEKILEQVRE EFSNQSKSLL
FASPAEEKIW RRADAFLVSP GIPMYYPTWH PLYKVAHGQG IPLYCDIEFL YQKTNKNVGF
IGITGTNGKS TTTALINHVL RSVKIKTEIG GNIGTPVLEL EELNSGFYVL EVSSFQLDLL
EKTRFNIAVC LTITPDHLDK HGTFKRYVEA KQQMFNNQEK GDLAIISTDS YINNQIMSEV
IARKRAKVIP ISRTEQIEGG VSVISGVLYD NYKSKKRYNV PDINSLIGEH NGENMAAAFT
ACIGVGVKPE EVIAAFKTYK SLPHRMDLFH RFNGINFIND SKATNADSTY WALKNFDNVY
WIAGGICKDS GIKLLKPFFE KINHAYLIGD AAEGFAAILA ESNVPYTIAT TLVNAISIIK
AQNIENGNVL LSPACASLDQ WKNYEERGNA FMKLVKEKWP G


Related products :

Catalog number Product name Quantity
U0162b CLIA Bos taurus,Bovine,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS 96T
E0162b ELISA Bos taurus,Bovine,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS 96T
U0162p CLIA GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Pig,Sus scrofa 96T
E0162p ELISA kit GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Pig,Sus scrofa 96T
E0162b ELISA kit Bos taurus,Bovine,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS 96T
E0162p ELISA GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Pig,Sus scrofa 96T
E0162r ELISA kit Glns,Glul,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Rat,Rattus norvegicus 96T
E0162r ELISA Glns,Glul,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Rat,Rattus norvegicus 96T
E0162m ELISA kit Glns,Glul,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Mouse,Mus musculus 96T
E0162m ELISA Glns,Glul,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Mouse,Mus musculus 96T
U0162r CLIA Glns,Glul,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Rat,Rattus norvegicus 96T
U0162m CLIA Glns,Glul,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Mouse,Mus musculus 96T
26-904 Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit a 0.05 mg
E0162h ELISA kit GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Homo sapiens,Human 96T
U0162h CLIA GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Homo sapiens,Human 96T
E0162h ELISA GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,Homo sapiens,Human 96T
18-783-77681 RABBIT ANTI HUMAN GLUTAMATE DECARBOXYLASE - GLUTAMATE DEHYDROGENASE; EC 4.1.1.15; Glutamate decarboxylase 67 kDa isoform; GAD-67; 67 kDa glutamic acid decarboxylase Polyclonal 0.05 ml
E0162c ELISA kit Chicken,Gallus gallus,GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,p42 96T
E0162c ELISA Chicken,Gallus gallus,GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,p42 96T
U0162c CLIA Chicken,Gallus gallus,GLNS,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS,p42 96T
U0162c CLIA Canis familiaris,Canis lupus familiaris,Dog,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS 96T
E0162c ELISA kit Canis familiaris,Canis lupus familiaris,Dog,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS 96T
E0162c ELISA Canis familiaris,Canis lupus familiaris,Dog,GLUL,Glutamate decarboxylase,Glutamate--ammonia ligase,Glutamine synthetase,GS 96T
E1258h ELISA 67 kDa glutamic acid decarboxylase,GAD,GAD1,GAD67,GAD-67,Glutamate decarboxylase 1,Glutamate decarboxylase 67 kDa isoform,Homo sapiens,Human 96T
U1258h CLIA 67 kDa glutamic acid decarboxylase,GAD,GAD1,GAD67,GAD-67,Glutamate decarboxylase 1,Glutamate decarboxylase 67 kDa isoform,Homo sapiens,Human 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur