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UTX (Ubiquitously transcribed TPR on X) homolog

 A0A131MBT2_CAEEL        Unreviewed;      1146 AA.
A0A131MBT2;
11-MAY-2016, integrated into UniProtKB/TrEMBL.
11-MAY-2016, sequence version 1.
22-NOV-2017, entry version 15.
SubName: Full=UTX (Ubiquitously transcribed TPR on X) homolog {ECO:0000313|EMBL:CZR14611.1};
Name=utx-1 {ECO:0000313|EMBL:CZR14611.1,
ECO:0000313|WormBase:D2021.1a};
ORFNames=CELE_D2021.1 {ECO:0000313|EMBL:CZR14611.1},
D2021.1 {ECO:0000313|WormBase:D2021.1a};
Caenorhabditis elegans.
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
NCBI_TaxID=6239 {ECO:0000313|EMBL:CZR14611.1};
[1] {ECO:0000313|EMBL:CZR14611.1, ECO:0000313|Proteomes:UP000001940}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2 {ECO:0000313|EMBL:CZR14611.1,
ECO:0000313|Proteomes:UP000001940};
PubMed=9851916; DOI=https://doi.org/10.1126/science.282.5396.2012;
The C. elegans sequencing consortium;
Sulson J.E., Waterston R.;
"Genome sequence of the nematode C. elegans: a platform for
investigating biology.";
Science 282:2012-2018(1998).
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EMBL; BX284606; CZR14611.1; -; Genomic_DNA.
RefSeq; NP_001309685.1; NM_001322626.1.
SMR; A0A131MBT2; -.
STRING; 6239.D2021.1; -.
GeneID; 181110; -.
KEGG; cel:CELE_D2021.1; -.
CTD; 181110; -.
WormBase; D2021.1a; CE51475; WBGene00017046; utx-1.
KO; K11447; -.
Proteomes; UP000001940; Chromosome X.
ExpressionAtlas; A0A131MBT2; baseline and differential.
GO; GO:0044666; C:MLL3/4 complex; IDA:WormBase.
GO; GO:0071557; P:histone H3-K27 demethylation; IMP:WormBase.
Gene3D; 1.25.40.10; -; 4.
InterPro; IPR003347; JmjC_dom.
InterPro; IPR013026; TPR-contain_dom.
InterPro; IPR011990; TPR-like_helical_dom_sf.
InterPro; IPR019734; TPR_repeat.
Pfam; PF02373; JmjC; 1.
SMART; SM00558; JmjC; 1.
SMART; SM00028; TPR; 5.
SUPFAM; SSF48452; SSF48452; 3.
PROSITE; PS51184; JMJC; 1.
PROSITE; PS50005; TPR; 4.
PROSITE; PS50293; TPR_REGION; 2.
1: Evidence at protein level;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000001940};
Proteomics identification {ECO:0000213|EPD:A0A131MBT2,
ECO:0000213|PeptideAtlas:A0A131MBT2};
Reference proteome {ECO:0000313|Proteomes:UP000001940};
TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
DOMAIN 101 209 TPR_REGION.
{ECO:0000259|PROSITE:PS50293}.
REPEAT 139 172 TPR. {ECO:0000256|PROSITE-
ProRule:PRU00339}.
REPEAT 176 209 TPR. {ECO:0000256|PROSITE-
ProRule:PRU00339}.
DOMAIN 354 421 TPR_REGION.
{ECO:0000259|PROSITE:PS50293}.
REPEAT 354 387 TPR. {ECO:0000256|PROSITE-
ProRule:PRU00339}.
REPEAT 388 421 TPR. {ECO:0000256|PROSITE-
ProRule:PRU00339}.
DOMAIN 841 1004 JmjC. {ECO:0000259|PROSITE:PS51184}.
COILED 224 248 {ECO:0000256|SAM:Coils}.
SEQUENCE 1146 AA; 131754 MW; 010CD4FC70F38451 CRC64;
MNTVSLLTPP MDESEPLPEE RHPGNFKKWL ELPLLTNYEL ERIRTLSSLS FDEFHVQNPA
DLTYQVRLFF AKARQYLVRY VDEMKSIYKT HKYKTIERRI FYGLAKQCHV VLLANDWTGA
LELYQEVLSH HPDLFSHDPS MYFGLGLVYL HFKQWKPAIE AFTRLLYSFP TGMIALQAKV
RLGVCYMELE DYNRCINLFK LAVNDSDESV FMPKFTIKYN IALSHENNDE LEIAESEYEN
LITELTQHIS FLQSKSNVDQ QQVDLLISVK AACLRQIGWI SYRRSYKDDA NRLDHLKKAQ
ENLISAHDTD PRDGQSYYYL GRVYGEHEPS VSGQVAHDAF VNYRFSIDKK EQNADTWCSI
GALYQRQNQP IDALQAFICA IELNSTHSAA WTDLGELYEK NAQYQDALEC FKNAMLNNPV
APEPIKARVQ FLEKELSMPV PARPSNHASS STFETVIPSL KEAYEQPIPL ELRNRQDAAY
ADREAQYDNA FWDLWEDFRT MEHEKPEDME WDVTYPRPME DLEIQVMQLL RANEPALVKA
EREVLECLET SEAVFKAKVI EYVIPEAVRE MPRVTEEMIQ NLRDHGHLLE SPRCYSFPFL
PKISFNDLPD SFSLLSELYV SMDISAQEIM QMVHRRTQPN STYLPVFEEF AKLPEPPRGP
VKPIVTDEDV RTALERSEKH PLILKTPILT VDNRKEAQSL ELQRFLDGST ISCIRGLTGC
LRLDLSLFST KAVAEIDGNQ EIEIRTQYQL PPETNCDHAS QQTWQCVSDP SYTTVNKYAE
YQSESFKHTL KGEAEKIKKN VGGTRGPSPK RMKLYKRASS PPKHLKSIKY GTNIDLSDDT
KWGKQINELS KLPAFCRLIA GSNMLSHLGH QVHGMNTVKL FMKVPGCRTP AHQDSNHMAS
ININIGPGDC EWFAVPYEYW GKMHKLCEKN GVDLLTGTFW PIIDDLLDAG IPVHRFTQKA
GDMVYVSGGA IHWVQASGWC NNISWNVAPL NFQQLSISLL SYEYNKLRRF KSEVPMQLMC
WQVAKNVKFT NQLIYNTCKG VLIRSLAFLR MVADYIVSQK KTIKAHTRTS GEQSHFCMTC
ECEVFCILFV KDIGGKFTVF CVYCAKSQGI EGFIALQQFS FTDLYSIYDN MKYIPAANNN
KMSFTA


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